Gustavo C Roman

Summary

Affiliation: University of Texas Health Science Center
Country: USA

Publications

  1. ncbi request reprint Donepezil in vascular dementia: combined analysis of two large-scale clinical trials
    Gustavo C Roman
    Department of Medicine Neurology, University of Texas Health Science Center and Audie Murphy Veterans Hospital, San Antonio, Tex 78229 3900, USA
    Dement Geriatr Cogn Disord 20:338-44. 2005
  2. ncbi request reprint Donepezil in vascular dementia: a viewpoint by Gustavo C. Román
    Gustavo C Roman
    Department of Medicine, Division of Neurology, University of Texas Health Sciences Center at San Antonio, San Antonio, Texas, USA
    Drugs Aging 20:1137-8. 2003
  3. ncbi request reprint Vascular dementia prevention: a risk factor analysis
    Gustavo C Roman
    Department of Medicine Neurology, University of Texas Health Science Center at San Antonio, San Antonio, Tex 78229 3900, USA
    Cerebrovasc Dis 20:91-100. 2005
  4. ncbi request reprint Vascular depression: An archetypal neuropsychiatric disorder
    Gustavo C Roman
    Department of Medicine and Neurology, University of Texas Health Science Center at San Antonio, 6707 Democracy Boulevard Suite 202, MSC 5477, San Antonio, Texas, USA
    Biol Psychiatry 60:1306-8. 2006
  5. ncbi request reprint Vascular determinants of cholinergic deficits in Alzheimer disease and vascular dementia
    Gustavo C Roman
    University of Texas Health Science Center, 7703 Floyd Curl Drive, San Antonio, TX 78229 3900, USA
    Neurobiol Aging 27:1769-85. 2006
  6. ncbi request reprint A diagnostic dilemma: is "Alzheimer's dementia" Alzheimer's disease, vascular dementia, or both?
    Gustavo C Roman
    University of Texas Health Science Center at San Antonio and the Audie L Murphy Veterans Hospital, San Antonio, Texas, USA
    Lancet Neurol 3:141. 2004
  7. ncbi request reprint Donepezil: a clinical review of current and emerging indications
    Gustavo C Roman
    Medicine Neurology, Mail Code 7883, University of Texas HSC, 7703 Floyd Curl Drive, San Antonio, TX 78229 3900, USA
    Expert Opin Pharmacother 5:161-80. 2004
  8. ncbi request reprint Rivastigmine for subcortical vascular dementia
    Gustavo C Roman
    University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, Mail Code 7883, San Antonio, TX 78229 3900, USA
    Expert Rev Neurother 5:309-13. 2005
  9. ncbi request reprint Cholinergic dysfunction in vascular dementia
    Gustavo C Roman
    Department of Medicine Neurology, University of Texas Health Science Center at San Antonio, and the Audie Murphy Veterans Administration Hospital, San Antonio, TX 78232, USA
    Curr Psychiatry Rep 7:18-26. 2005
  10. ncbi request reprint Vascular cognitive disorder: a new diagnostic category updating vascular cognitive impairment and vascular dementia
    Gustavo C Roman
    Department of Medicine Neurology, University of Texas HSC at San Antonio and the Audie Murphy Veterans Administration Hospital, Mail Code 7883, 7703 Floyd Curl Drive, San Antonio, TX 78229 3900, USA
    J Neurol Sci 226:81-7. 2004

Detail Information

Publications15

  1. ncbi request reprint Donepezil in vascular dementia: combined analysis of two large-scale clinical trials
    Gustavo C Roman
    Department of Medicine Neurology, University of Texas Health Science Center and Audie Murphy Veterans Hospital, San Antonio, Tex 78229 3900, USA
    Dement Geriatr Cogn Disord 20:338-44. 2005
    ..There are currently no drugs approved to treat vascular dementia (VaD). The objective of this study was to determine if treatment with donepezil, an acetylcholinesterase inhibitor, may provide benefit for VaD patients...
  2. ncbi request reprint Donepezil in vascular dementia: a viewpoint by Gustavo C. Román
    Gustavo C Roman
    Department of Medicine, Division of Neurology, University of Texas Health Sciences Center at San Antonio, San Antonio, Texas, USA
    Drugs Aging 20:1137-8. 2003
  3. ncbi request reprint Vascular dementia prevention: a risk factor analysis
    Gustavo C Roman
    Department of Medicine Neurology, University of Texas Health Science Center at San Antonio, San Antonio, Tex 78229 3900, USA
    Cerebrovasc Dis 20:91-100. 2005
    ..Evidence from controlled clinical trials strongly suggests that control of vascular risk factors, in particular hypertension, could prevent the development of dementia...
  4. ncbi request reprint Vascular depression: An archetypal neuropsychiatric disorder
    Gustavo C Roman
    Department of Medicine and Neurology, University of Texas Health Science Center at San Antonio, 6707 Democracy Boulevard Suite 202, MSC 5477, San Antonio, Texas, USA
    Biol Psychiatry 60:1306-8. 2006
  5. ncbi request reprint Vascular determinants of cholinergic deficits in Alzheimer disease and vascular dementia
    Gustavo C Roman
    University of Texas Health Science Center, 7703 Floyd Curl Drive, San Antonio, TX 78229 3900, USA
    Neurobiol Aging 27:1769-85. 2006
    ..We postulate that vascular pathology likely plays a common role in initiating cholinergic neuronal abnormalities in VaD and AD...
  6. ncbi request reprint A diagnostic dilemma: is "Alzheimer's dementia" Alzheimer's disease, vascular dementia, or both?
    Gustavo C Roman
    University of Texas Health Science Center at San Antonio and the Audie L Murphy Veterans Hospital, San Antonio, Texas, USA
    Lancet Neurol 3:141. 2004
  7. ncbi request reprint Donepezil: a clinical review of current and emerging indications
    Gustavo C Roman
    Medicine Neurology, Mail Code 7883, University of Texas HSC, 7703 Floyd Curl Drive, San Antonio, TX 78229 3900, USA
    Expert Opin Pharmacother 5:161-80. 2004
    ....
  8. ncbi request reprint Rivastigmine for subcortical vascular dementia
    Gustavo C Roman
    University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, Mail Code 7883, San Antonio, TX 78229 3900, USA
    Expert Rev Neurother 5:309-13. 2005
    ..Rivastigmine appears to be a promising agent in vascular dementia but its effects remain to be established in double-blind, placebo-controlled clinical trials...
  9. ncbi request reprint Cholinergic dysfunction in vascular dementia
    Gustavo C Roman
    Department of Medicine Neurology, University of Texas Health Science Center at San Antonio, and the Audie Murphy Veterans Administration Hospital, San Antonio, TX 78232, USA
    Curr Psychiatry Rep 7:18-26. 2005
    ..Cholinergic stimulation produces increases in cortical cerebral blood flow that may be relevant to the therapeutic effect of ChEIs...
  10. ncbi request reprint Vascular cognitive disorder: a new diagnostic category updating vascular cognitive impairment and vascular dementia
    Gustavo C Roman
    Department of Medicine Neurology, University of Texas HSC at San Antonio and the Audie Murphy Veterans Administration Hospital, Mail Code 7883, 7703 Floyd Curl Drive, San Antonio, TX 78229 3900, USA
    J Neurol Sci 226:81-7. 2004
    ..It would include specific disease entities such as post-stroke VCI, post-stroke VaD, CADASIL, Binswanger disease, and AD plus CVD. This category explicitly excludes isolated cognitive dysfunctions such as those mentioned above...
  11. ncbi request reprint Brain hypoperfusion: a critical factor in vascular dementia
    Gustavo C Roman
    University of Texas Health Science Center at San Antonio and the Audie L Murphy Memorial Veterans Hospital, Geriatric Research Education and Clinical Center, San Antonio, USA
    Neurol Res 26:454-8. 2004
    ..Recognition of the susceptibility of elderly subjects to cerebral lesions induced by hypoperfusion should result in appropriate preventive measures and better treatment...
  12. ncbi request reprint Myelopathy in Sjögren's syndrome: role of nonsteroidal immunosuppressants
    Susan J Rogers
    University of Texas Health Sciences Center at San Antonio, San Antonio, Texas 78229 3900, USA
    Drugs 64:123-32. 2004
    ..This agent might be considered when all other treatment modalities have failed given the presumed importance of tumour necrosis factor in the pathogenesis of Sjögren's syndrome...
  13. ncbi request reprint Subcortical ischaemic vascular dementia
    Gustavo C Roman
    University of Texas at San Antonio and the Audie L Murphy Memorial Veterans Hospital, San Antonio, Texas 78284 7883, USA
    Lancet Neurol 1:426-36. 2002
    ..Treatment is symptomatic and prevention requires control of treatable risk factors...
  14. ncbi request reprint Vascular dementia may be the most common form of dementia in the elderly
    Gustavo C Roman
    University of Texas Health Sciences Center, 7703 Floyd Curl Dr, San Antonio, TX 78284 6200, USA
    J Neurol Sci 203:7-10. 2002
    ..In conclusion, VaD may be the most underdiagnosed and undertreated form of dementia in the elderly...
  15. ncbi request reprint Vascular dementia revisited: diagnosis, pathogenesis, treatment, and prevention
    Gustavo C Roman
    Department of Medicine Neurology, University of Texas Health Science Center, Audie L Murphy Memorial Veterans Hospital, 7703 Floyd Curl Drive, San Antonio, TX 78284 7883, USA
    Med Clin North Am 86:477-99. 2002
    ..Anticholinergic medications used for AD are also useful in VaD, and atypical antipsychotic agents and antidepressants (e.g., selective serotonin reuptake inhibitors) may be required in some patients...