Research Topics

Oskar W Rokhlin


Affiliation: University of Iowa
Country: USA


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    Rokhlin O, Glover R, Taghiyev A, Guseva N, Seftor R, Shyshynova I, et al. Bisindolylmaleimide IX facilitates tumor necrosis factor receptor family-mediated cell death and acts as an inhibitor of transcription. J Biol Chem. 2002;277:33213-9 pubmed
    ..In summary, these results suggest that Bis IX potentiates TNF receptor family-mediated cell death in part as an inhibitor of transcription. ..
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    Rokhlin O, Guseva N, Taghiyev A, Glover R, Cohen M. KN-93 inhibits androgen receptor activity and induces cell death irrespective of p53 and Akt status in prostate cancer. Cancer Biol Ther. 2010;9:224-35 pubmed
    ..These data suggest that KN-93 could be used for novel therapeutic approaches when hormonal therapy has failed. ..