Kyle H Rohde
Affiliation: University of Central Florida
- Linking the transcriptional profiles and the physiological states of Mycobacterium tuberculosis during an extended intracellular infectionKyle H Rohde
Department of Microbiology and Immunology, Cornell University, Ithaca, New York, United States of America
PLoS Pathog 8:e1002769. 2012..The integration of molecular and cellular biology together with transcriptional profiling and systems analysis offers unique insights into the host-driven responses of intracellular pathogens such as M. tuberculosis...
- aprABC: a Mycobacterium tuberculosis complex-specific locus that modulates pH-driven adaptation to the macrophage phagosomeRobert B Abramovitch
Department of Microbiology and Immunology, Cornell University, Ithaca, NY 14583, USA
Mol Microbiol 80:678-94. 2011..We propose a model where phoPR senses the acidic pH of the phagosome and induces aprABC expression to fine-tune processes unique for intracellular adaptation of Mtb complex bacteria...
- Mycobacterium tuberculosis invasion of macrophages: linking bacterial gene expression to environmental cuesKyle H Rohde
Cornell University, College of Veterinary Medicine, Department of Microbiology and Immunology, Ithaca, NY 14853, USA
Cell Host Microbe 2:352-64. 2007..Finally, there are marked species-specific differences in the response of Mtb and M. bovis BCG to intraphagosomal cues...
- Transcriptional responses of Mycobacterium tuberculosis to lung surfactantUte Schwab
Department of Microbiology and Immunology, Cornell University College of Veterinary Medicine, Ithaca, NY 14853, USA
Microb Pathog 46:185-93. 2009....
- Mycobacterium tuberculosis wears what it eatsDavid G Russell
Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA
Cell Host Microbe 8:68-76. 2010..Understanding these environments, and the stresses that they place on M. tuberculosis, should provide insights invaluable for the development of new chemo- and immunotherapeutic strategies...