Evgeny Rogaev

Summary

Affiliation: University of Massachusetts Medical School
Country: USA

Publications

  1. ncbi request reprint Dinucleotide repeat polymorphisms at the P1, HBE1 and MYH7 loci
    E I Rogaev
    National Research Center of Mental Health, Laboratory of Molecular Brain Genetics, Academy of Medical Sciences, Moscow, Russia
    Hum Mol Genet 1:285. 1992
  2. ncbi request reprint Linkage of polymorphic congenital cataract to the gamma-crystallin gene locus on human chromosome 2q33-35
    E I Rogaev
    Laboratory of Molecular Brain Genetics, Russian Academy of Medical Sciences, Moscow, Russia
    Hum Mol Genet 5:699-703. 1996
  3. ncbi request reprint MicroRNA in schizophrenia: genetic and expression analysis of miR-130b (22q11)
    O A Burmistrova
    Research Center of Mental Health, Russian Academy Medical Sciences, Moscow 113152, Russia
    Biochemistry (Mosc) 72:578-82. 2007
  4. ncbi request reprint Small RNAs in human brain development and disorders
    E I Rogaev
    Brudnick Neuropsychiatric Research Institute, Department of Psychiatry, University of Massachusetts Medical School, Worcester, MA 01604, USA
    Biochemistry (Mosc) 70:1404-7. 2005
  5. pmc Complete mitochondrial genome and phylogeny of Pleistocene mammoth Mammuthus primigenius
    Evgeny I Rogaev
    Brudnick Neuropsychiatric Research Institute, Department of Psychiatry, University of Massachusetts Medical School, Worcester, Massachusetts, USA
    PLoS Biol 4:e73. 2006
  6. doi request reprint Genotype analysis identifies the cause of the "royal disease"
    Evgeny I Rogaev
    University of Massachusetts Medical School, 303 Belmont Street, Worcester, MA 01604, USA
    Science 326:817. 2009
  7. pmc Gender-specific reduction of estrogen-sensitive small RNA, miR-30b, in subjects with schizophrenia
    Nikolaos Mellios
    Department of Psychiatry, Brudnick Neuropsychiatric Research Institute, Worcester, MA, USA
    Schizophr Bull 38:433-43. 2012
  8. pmc Epigenetics in the human brain
    Isaac Houston
    Brudnick Neuropsychiatric Research Institute, Department of Psychiatry, University of Massachusetts Medical School, Worcester, MA 01604, USA
    Neuropsychopharmacology 38:183-97. 2013
  9. pmc Role for glyoxalase I in Alzheimer's disease
    Feng Chen
    Division of Psychiatry Research, University of Zurich, August Forel Strasse 1, 8008 Zurich, Switzerland
    Proc Natl Acad Sci U S A 101:7687-92. 2004
  10. pmc Conversion and compensatory evolution of the gamma-crystallin genes and identification of a cataractogenic mutation that reverses the sequence of the human CRYGD gene to an ancestral state
    Olga V Plotnikova
    Laboratory of Molecular Brain Genetics, Research Center of Mental Health, Russian Academy of Medical Sciences, and Lomonosov Moscow State University, Moscow, Russia
    Am J Hum Genet 81:32-43. 2007

Research Grants

  1. Function of intramembrane aspartic protease
    Evgeny Rogaev; Fiscal Year: 2009
  2. Regulation of Presenilin Genes
    Evgeny Rogaev; Fiscal Year: 2007
  3. Molecular-Genetic Mechanisms for Early-Onset Obesity
    Evgeny Rogaev; Fiscal Year: 2006
  4. Function of intramembrane aspartic protease
    Evgeny I Rogaev; Fiscal Year: 2010

Collaborators

Detail Information

Publications10

  1. ncbi request reprint Dinucleotide repeat polymorphisms at the P1, HBE1 and MYH7 loci
    E I Rogaev
    National Research Center of Mental Health, Laboratory of Molecular Brain Genetics, Academy of Medical Sciences, Moscow, Russia
    Hum Mol Genet 1:285. 1992
  2. ncbi request reprint Linkage of polymorphic congenital cataract to the gamma-crystallin gene locus on human chromosome 2q33-35
    E I Rogaev
    Laboratory of Molecular Brain Genetics, Russian Academy of Medical Sciences, Moscow, Russia
    Hum Mol Genet 5:699-703. 1996
    ..This defect is characterised by complete penetrance but variable expression of the cataract phenotype. Our study also suggests that non-nuclear human cataracts might be caused by some abnormality in gamma-crystallin genes...
  3. ncbi request reprint MicroRNA in schizophrenia: genetic and expression analysis of miR-130b (22q11)
    O A Burmistrova
    Research Center of Mental Health, Russian Academy Medical Sciences, Moscow 113152, Russia
    Biochemistry (Mosc) 72:578-82. 2007
    ..The data demonstrated feasibility and perspective of convergent genetic and expression analysis of human microRNA genes in testing their role in human diseases...
  4. ncbi request reprint Small RNAs in human brain development and disorders
    E I Rogaev
    Brudnick Neuropsychiatric Research Institute, Department of Psychiatry, University of Massachusetts Medical School, Worcester, MA 01604, USA
    Biochemistry (Mosc) 70:1404-7. 2005
    ..The abundant expression of many regulatory small RNAs in human brain implies their biological role that must be tested by functional assays in neurons and by genetic and comparative expression profiling...
  5. pmc Complete mitochondrial genome and phylogeny of Pleistocene mammoth Mammuthus primigenius
    Evgeny I Rogaev
    Brudnick Neuropsychiatric Research Institute, Department of Psychiatry, University of Massachusetts Medical School, Worcester, Massachusetts, USA
    PLoS Biol 4:e73. 2006
    ..primigenius throughout the late Pleistocene...
  6. doi request reprint Genotype analysis identifies the cause of the "royal disease"
    Evgeny I Rogaev
    University of Massachusetts Medical School, 303 Belmont Street, Worcester, MA 01604, USA
    Science 326:817. 2009
    ..Thus, the royal disease is the severe form of hemophilia, also known as hemophilia B or Christmas disease...
  7. pmc Gender-specific reduction of estrogen-sensitive small RNA, miR-30b, in subjects with schizophrenia
    Nikolaos Mellios
    Department of Psychiatry, Brudnick Neuropsychiatric Research Institute, Worcester, MA, USA
    Schizophr Bull 38:433-43. 2012
    ..These preliminary findings point to the possibility that disease-related changes in the expression of small noncoding RNAs such as miR-30b in schizophrenia could be influenced by gender and potentially regulated by estrogen signaling...
  8. pmc Epigenetics in the human brain
    Isaac Houston
    Brudnick Neuropsychiatric Research Institute, Department of Psychiatry, University of Massachusetts Medical School, Worcester, MA 01604, USA
    Neuropsychopharmacology 38:183-97. 2013
    ....
  9. pmc Role for glyoxalase I in Alzheimer's disease
    Feng Chen
    Division of Psychiatry Research, University of Zurich, August Forel Strasse 1, 8008 Zurich, Switzerland
    Proc Natl Acad Sci U S A 101:7687-92. 2004
    ..Together, our data demonstrate the potential of transcriptomics applied to animal models of human diseases. They suggest a previously unidentified role for glyoxalase I in neurodegenerative disease...
  10. pmc Conversion and compensatory evolution of the gamma-crystallin genes and identification of a cataractogenic mutation that reverses the sequence of the human CRYGD gene to an ancestral state
    Olga V Plotnikova
    Laboratory of Molecular Brain Genetics, Research Center of Mental Health, Russian Academy of Medical Sciences, and Lomonosov Moscow State University, Moscow, Russia
    Am J Hum Genet 81:32-43. 2007
    ....

Research Grants11

  1. Function of intramembrane aspartic protease
    Evgeny Rogaev; Fiscal Year: 2009
    ..We plan to provide evidence for the essential role of this protein in CNS development and signaling in neurulation, which if disrupted, underlies anencephaly, a most common congenital brain defect in humans. ..
  2. Regulation of Presenilin Genes
    Evgeny Rogaev; Fiscal Year: 2007
    ..These studies will contribute to identification of molecular factors regulating the primary causes of AD, and ultimately, to the development of new strategies for prevention and rational therapy of Alzheimer's disease. ..
  3. Molecular-Genetic Mechanisms for Early-Onset Obesity
    Evgeny Rogaev; Fiscal Year: 2006
    ..abstract_text> ..
  4. Function of intramembrane aspartic protease
    Evgeny I Rogaev; Fiscal Year: 2010
    ..We plan to provide evidence for the essential role of this protein in CNS development and signaling in neurulation, which if disrupted, underlies anencephaly, a most common congenital brain defect in humans. ..