Evgeny Rogaev

Summary

Affiliation: University of Massachusetts Medical School
Country: USA

Publications

  1. ncbi Small RNAs in human brain development and disorders
    E I Rogaev
    Brudnick Neuropsychiatric Research Institute, Department of Psychiatry, University of Massachusetts Medical School, Worcester, MA 01604, USA
    Biochemistry (Mosc) 70:1404-7. 2005
  2. ncbi Complete mitochondrial genome and phylogeny of Pleistocene mammoth Mammuthus primigenius
    Evgeny I Rogaev
    Brudnick Neuropsychiatric Research Institute, Department of Psychiatry, University of Massachusetts Medical School, Worcester, Massachusetts, USA
    PLoS Biol 4:e73. 2006
  3. ncbi Genotype analysis identifies the cause of the "royal disease"
    Evgeny I Rogaev
    University of Massachusetts Medical School, 303 Belmont Street, Worcester, MA 01604, USA
    Science 326:817. 2009
  4. ncbi Gender-specific reduction of estrogen-sensitive small RNA, miR-30b, in subjects with schizophrenia
    Nikolaos Mellios
    Department of Psychiatry, Brudnick Neuropsychiatric Research Institute, Worcester, MA, USA
    Schizophr Bull 38:433-43. 2012
  5. ncbi Epigenetics in the human brain
    Isaac Houston
    Brudnick Neuropsychiatric Research Institute, Department of Psychiatry, University of Massachusetts Medical School, Worcester, MA 01604, USA
    Neuropsychopharmacology 38:183-97. 2013
  6. ncbi Role for glyoxalase I in Alzheimer's disease
    Feng Chen
    Division of Psychiatry Research, , August Forel Strasse 1, 8008 Zurich, Switzerland
    Proc Natl Acad Sci U S A 101:7687-92. 2004
  7. ncbi Conversion and compensatory evolution of the gamma-crystallin genes and identification of a cataractogenic mutation that reverses the sequence of the human CRYGD gene to an ancestral state
    Olga V Plotnikova
    Laboratory of Molecular Brain Genetics, Research Center of Mental Health, Russian Academy of Medical Sciences, and Lomonosov Moscow State University, Moscow, Russia
    Am J Hum Genet 81:32-43. 2007

Research Grants

  1. Function of intramembrane aspartic protease
    Evgeny Rogaev; Fiscal Year: 2009
  2. Regulation of Presenilin Genes
    Evgeny Rogaev; Fiscal Year: 2007
  3. Molecular-Genetic Mechanisms for Early-Onset Obesity
    Evgeny Rogaev; Fiscal Year: 2006
  4. Function of intramembrane aspartic protease
    Evgeny I Rogaev; Fiscal Year: 2010

Collaborators

Detail Information

Publications7

  1. ncbi Small RNAs in human brain development and disorders
    E I Rogaev
    Brudnick Neuropsychiatric Research Institute, Department of Psychiatry, University of Massachusetts Medical School, Worcester, MA 01604, USA
    Biochemistry (Mosc) 70:1404-7. 2005
    ..The abundant expression of many regulatory small RNAs in human brain implies their biological role that must be tested by functional assays in neurons and by genetic and comparative expression profiling...
  2. ncbi Complete mitochondrial genome and phylogeny of Pleistocene mammoth Mammuthus primigenius
    Evgeny I Rogaev
    Brudnick Neuropsychiatric Research Institute, Department of Psychiatry, University of Massachusetts Medical School, Worcester, Massachusetts, USA
    PLoS Biol 4:e73. 2006
    ..primigenius throughout the late Pleistocene...
  3. ncbi Genotype analysis identifies the cause of the "royal disease"
    Evgeny I Rogaev
    University of Massachusetts Medical School, 303 Belmont Street, Worcester, MA 01604, USA
    Science 326:817. 2009
    ..Thus, the royal disease is the severe form of hemophilia, also known as hemophilia B or Christmas disease...
  4. ncbi Gender-specific reduction of estrogen-sensitive small RNA, miR-30b, in subjects with schizophrenia
    Nikolaos Mellios
    Department of Psychiatry, Brudnick Neuropsychiatric Research Institute, Worcester, MA, USA
    Schizophr Bull 38:433-43. 2012
    ..These preliminary findings point to the possibility that disease-related changes in the expression of small noncoding RNAs such as miR-30b in schizophrenia could be influenced by gender and potentially regulated by estrogen signaling...
  5. ncbi Epigenetics in the human brain
    Isaac Houston
    Brudnick Neuropsychiatric Research Institute, Department of Psychiatry, University of Massachusetts Medical School, Worcester, MA 01604, USA
    Neuropsychopharmacology 38:183-97. 2013
    ....
  6. ncbi Role for glyoxalase I in Alzheimer's disease
    Feng Chen
    Division of Psychiatry Research, , August Forel Strasse 1, 8008 Zurich, Switzerland
    Proc Natl Acad Sci U S A 101:7687-92. 2004
    ..Together, our data demonstrate the potential of transcriptomics applied to animal models of human diseases. They suggest a previously unidentified role for glyoxalase I in neurodegenerative disease...
  7. ncbi Conversion and compensatory evolution of the gamma-crystallin genes and identification of a cataractogenic mutation that reverses the sequence of the human CRYGD gene to an ancestral state
    Olga V Plotnikova
    Laboratory of Molecular Brain Genetics, Research Center of Mental Health, Russian Academy of Medical Sciences, and Lomonosov Moscow State University, Moscow, Russia
    Am J Hum Genet 81:32-43. 2007
    ....

Research Grants11

  1. Function of intramembrane aspartic protease
    Evgeny Rogaev; Fiscal Year: 2009
    ..We plan to provide evidence for the essential role of this protein in CNS development and signaling in neurulation, which if disrupted, underlies anencephaly, a most common congenital brain defect in humans. ..
  2. Regulation of Presenilin Genes
    Evgeny Rogaev; Fiscal Year: 2007
    ..These studies will contribute to identification of molecular factors regulating the primary causes of AD, and ultimately, to the development of new strategies for prevention and rational therapy of Alzheimer's disease. ..
  3. Molecular-Genetic Mechanisms for Early-Onset Obesity
    Evgeny Rogaev; Fiscal Year: 2006
    ..abstract_text> ..
  4. Function of intramembrane aspartic protease
    Evgeny I Rogaev; Fiscal Year: 2010
    ..We plan to provide evidence for the essential role of this protein in CNS development and signaling in neurulation, which if disrupted, underlies anencephaly, a most common congenital brain defect in humans. ..