Don Rockey

Summary

Affiliation: University of Texas Southwestern Medical Center
Country: USA

Publications

  1. ncbi request reprint Prospective comparison of air-contrast barium enema and colonoscopy in patients with fecal occult blood: a pilot study
    Don C Rockey
    Liver Center, Duke University Medical Center, Sands Building Room 334, Research Drive, Durham, NC 27710, USA
    Gastrointest Endosc 60:953-8. 2004
  2. doi request reprint Computed tomographic and magnetic resonance colonography: challenge for colonoscopy
    Don C Rockey
    Division of Digestive and Liver Diseases, University of Texas Southwestern Medical Center, Dallas, TX 75390 8887, USA
    Dig Dis 30:60-7. 2012
  3. pmc Preproendothelin-1 expression is negatively regulated by IFNγ during hepatic stellate cell activation
    Tianxia Li
    Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas 75390 8887, USA
    Am J Physiol Gastrointest Liver Physiol 302:G948-57. 2012
  4. pmc Serum proteomic analysis focused on fibrosis in patients with hepatitis C virus infection
    Ian R White
    Department of Disease and Biomarker Proteomics, GlaxoSmithKline Pharmaceuticals, Stevenage, UK
    J Transl Med 5:33. 2007
  5. ncbi request reprint Lower gastrointestinal bleeding
    Don C Rockey
    Department of Medicine, Division of Digestive and Liver Disease, University of Texas Southwestern Medical Center, Dallas, Texas 75390 8887, USA
    Gastroenterology 130:165-71. 2006
  6. ncbi request reprint Noninvasive measures of liver fibrosis
    Don C Rockey
    Department of Medicine, and the Division of Digestive and Liver Diseases, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
    Hepatology 43:S113-20. 2006
  7. ncbi request reprint Occult gastrointestinal bleeding
    Don C Rockey
    Division of Digestive and Liver Diseases, University of Texas Southwestern Medical Center, Dallas, 75390, USA
    Gastroenterol Clin North Am 34:699-718. 2005
  8. pmc Current and future anti-fibrotic therapies for chronic liver disease
    Don C Rockey
    Division of Digestive and Liver Diseases, Department of Internal Medicine, The University of Texas, Southwestern Medical Center, Dallas, TX 75390, USA
    Clin Liver Dis 12:939-62, xi. 2008
  9. doi request reprint Computed tomographic colonography
    Don C Rockey
    Division of Digestive and Liver Diseases, Southwestern Medical Center, University of Texas, Dallas, Texas 75390 8887, USA
    Curr Opin Gastroenterol 25:55-8. 2009
  10. ncbi request reprint Hepatic fibrosis, stellate cells, and portal hypertension
    Don C Rockey
    Division of Digestive and Liver Diseases, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390 8887, USA
    Clin Liver Dis 10:459-79, vii-viii. 2006

Collaborators

Detail Information

Publications66

  1. ncbi request reprint Prospective comparison of air-contrast barium enema and colonoscopy in patients with fecal occult blood: a pilot study
    Don C Rockey
    Liver Center, Duke University Medical Center, Sands Building Room 334, Research Drive, Durham, NC 27710, USA
    Gastrointest Endosc 60:953-8. 2004
    ..Thus, this study compared the sensitivity and the specificity of air-contrast barium enema and colonoscopy for detection of colonic lesions in patients with fecal occult blood...
  2. doi request reprint Computed tomographic and magnetic resonance colonography: challenge for colonoscopy
    Don C Rockey
    Division of Digestive and Liver Diseases, University of Texas Southwestern Medical Center, Dallas, TX 75390 8887, USA
    Dig Dis 30:60-7. 2012
    ..Computed tomographic (CT) and magnetic resonance (MR) colonography are new noninvasive techniques to examine the colon...
  3. pmc Preproendothelin-1 expression is negatively regulated by IFNγ during hepatic stellate cell activation
    Tianxia Li
    Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas 75390 8887, USA
    Am J Physiol Gastrointest Liver Physiol 302:G948-57. 2012
    ....
  4. pmc Serum proteomic analysis focused on fibrosis in patients with hepatitis C virus infection
    Ian R White
    Department of Disease and Biomarker Proteomics, GlaxoSmithKline Pharmaceuticals, Stevenage, UK
    J Transl Med 5:33. 2007
    ..To identify potential biomarkers of fibrosis, we compared serum protein expression profiles in patients with chronic hepatitis C (CHC) virus infection and fibrosis...
  5. ncbi request reprint Lower gastrointestinal bleeding
    Don C Rockey
    Department of Medicine, Division of Digestive and Liver Disease, University of Texas Southwestern Medical Center, Dallas, Texas 75390 8887, USA
    Gastroenterology 130:165-71. 2006
  6. ncbi request reprint Noninvasive measures of liver fibrosis
    Don C Rockey
    Department of Medicine, and the Division of Digestive and Liver Diseases, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
    Hepatology 43:S113-20. 2006
    ..The development of safe, inexpensive, and reliable noninvasive fibrosis measurement tools remains a research priority in clinical hepatology...
  7. ncbi request reprint Occult gastrointestinal bleeding
    Don C Rockey
    Division of Digestive and Liver Diseases, University of Texas Southwestern Medical Center, Dallas, 75390, USA
    Gastroenterol Clin North Am 34:699-718. 2005
    ..Both groups of patients are clinically challenging and require a focused and experienced team approach to diagnosis and therapy...
  8. pmc Current and future anti-fibrotic therapies for chronic liver disease
    Don C Rockey
    Division of Digestive and Liver Diseases, Department of Internal Medicine, The University of Texas, Southwestern Medical Center, Dallas, TX 75390, USA
    Clin Liver Dis 12:939-62, xi. 2008
    ..Preclinical studies have indicated several putative therapies that might abrogate fibrogenesis. This article emphasizes mechanisms underlying fibrogenesis and reviews available and future therapeutics...
  9. doi request reprint Computed tomographic colonography
    Don C Rockey
    Division of Digestive and Liver Diseases, Southwestern Medical Center, University of Texas, Dallas, Texas 75390 8887, USA
    Curr Opin Gastroenterol 25:55-8. 2009
    ..Computed tomographic colonography is a new and noninvasive method to evaluate the colon. The goal of this review is to discuss the latest data and define outstanding issues related to computed tomographic colonography...
  10. ncbi request reprint Hepatic fibrosis, stellate cells, and portal hypertension
    Don C Rockey
    Division of Digestive and Liver Diseases, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390 8887, USA
    Clin Liver Dis 10:459-79, vii-viii. 2006
    ..Given the central role of stellate cell activation in hepatic fibrogenesis (and portal hypertension), effective therapy for hepatic fibrogenesis is most likely will be directed at this event...
  11. doi request reprint Computed tomographic colonography: current perspectives and future directions
    Don C Rockey
    Division of Digestive and Liver Diseases, University of Texas Southwestern Medical Center, Dallas, Texas 75390 8887, USA
    Gastroenterology 137:7-14. 2009
    ..Although much about CT colonography has already been learned, more remains to be learned in the future...
  12. ncbi request reprint New therapies in hepatitis C virus and chronic liver disease: antifibrotics
    Don C Rockey
    Division of Digestive and Liver Diseases, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390 8887, USA
    Clin Liver Dis 10:881-900. 2006
    ..The aggregate data has not only helped lead to an understanding of the pathophysiologic basis of hepatic fibrogenesis, but it has also provided an important context with which to base novel antifibrotic therapy...
  13. doi request reprint Computed tomographic colonography: ready for prime time?
    Don C Rockey
    Division of Digestive and Liver Diseases, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390 8887, USA
    Gastroenterol Clin North Am 39:901-9. 2010
    ....
  14. doi request reprint Occult and obscure gastrointestinal bleeding: causes and clinical management
    Don C Rockey
    University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390 8887, USA
    Nat Rev Gastroenterol Hepatol 7:265-79. 2010
    ..In this Review the causes, diagnostic evaluation and treatment of occult and obscure gastrointestinal bleeding are discussed...
  15. pmc Causality assessment in drug-induced liver injury using a structured expert opinion process: comparison to the Roussel-Uclaf causality assessment method
    Don C Rockey
    Division of Digestive and Liver Diseases, University of Texas Southwestern Medical Center, Dallas, TX 75390 8887, USA
    Hepatology 51:2117-26. 2010
    ..42, P = 0.0001). Importantly, the RUCAM approach substantially shifted the causality likelihood toward lower probabilities in comparison with the DILIN expert opinion process...
  16. ncbi request reprint Pharmacologic therapy for gastrointestinal bleeding due to portal hypertension and esophageal varices
    Don C Rockey
    Division of Digestive and Liver Diseases, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390 8887, USA
    Curr Gastroenterol Rep 8:7-13. 2006
    ..For primary and secondary prevention of esophageal variceal hemorrhage, beta-blockers remain the mainstay therapy...
  17. pmc Microsatellite instability among individuals of Hispanic origin with colorectal cancer
    Samir Gupta
    Division of Digestive and Liver Diseases, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas 75390 8887, USA
    Cancer 116:4965-72. 2010
    ....
  18. ncbi request reprint Lower gastrointestinal bleeding--management
    Bryan T Green
    Division of Gastroenterology, Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA
    Gastroenterol Clin North Am 34:665-78. 2005
    ..3, Table 2). In patients who have aggressive bleeding or recurrent bleeding, it is critical for the practitioner to judge when angiography and surgery are necessary...
  19. ncbi request reprint Endoscopic hemostasis using endoclip in early gastrointestinal hemorrhage after gastric bypass surgery
    Shou Jiang Tang
    Division of Digestive and Liver Diseases, Department of Internal Medicine, UT Southwestern Medical Center, Dallas, TX 75390 8887, USA
    Obes Surg 17:1261-7. 2007
    ..We conclude that therapeutic endoscopy can be performed safely for early bleeding after RYGBP. In patients with early bleeding after RYGBP, use of endoclips is mechanistically preferable to other options...
  20. doi request reprint Endoscopic variceal ligation--is there any benefit to placing more than six bands?
    Shou Jiang Tang
    Division of Digestive and Liver Diseases, University of Texas, Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390 9151, USA
    Nat Clin Pract Gastroenterol Hepatol 5:198-9. 2008
  21. pmc Screening for colorectal cancer in a safety-net health care system: access to care is critical and has implications for screening policy
    Samir Gupta
    Department of Internal Medicine, Division of Digestive and Liver Diseases, The University of Texas Southwestern Medical Center, Dallas, TX 75390 8887, USA
    Cancer Epidemiol Biomarkers Prev 18:2373-9. 2009
    ..Data on the number of individuals eligible for screening, and rates of screening, are necessary to assess national colorectal cancer screening efforts. Such data are sparse for safety-net health systems...
  22. doi request reprint Endoscopic hemostasis in nonvariceal upper gastrointestinal bleeding: comparison of physician practice in the East and the West
    Shou Jiang Tang
    Department of Gastroenterology, Hepatology and Endoscopy, Trinity Mother Frances Hospitals and Clinics, Tyler, TX 75702, USA
    Dig Dis Sci 54:2418-26. 2009
    ..there would be differences in practice patterns among different groups of endoscopists...
  23. doi request reprint Management of small polyps detected by screening CT colonography: patient and physician preferences
    Jessica P Shah
    Division of Digestive and Liver Diseases, University of Texas Southwestern Medical Center, Dallas, TX 75390 8887, USA
    Am J Med 122:687.e1-9. 2009
    ..Patient and physician behavior are influenced by personal beliefs and prior experience. Thus, we aimed to understand patient and physician preferences after finding polyps on CT colonography...
  24. pmc Variation of agreement in polyp size measurement between computed tomographic colonography and pathology assessment: clinical implications
    Samir Gupta
    Division of Digestive and Liver Diseases, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390 8887, USA
    Clin Gastroenterol Hepatol 6:220-7. 2008
    ..We hypothesized that size measurement by CT colonography varies substantially compared with measurement by other methods...
  25. ncbi request reprint Gastrointestinal endoscopic evaluation of premenopausal women with iron deficiency anemia
    Bryan T Green
    Department of Internal Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA
    J Clin Gastroenterol 38:104-9. 2004
    ..To evaluate whether the gastrointestinal tract could be a source of chronic blood loss in premenopausal women with iron deficiency anemia...
  26. pmc Causes, clinical features, and outcomes from a prospective study of drug-induced liver injury in the United States
    Naga Chalasani
    Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    Gastroenterology 135:1924-34, 1934.e1-4. 2008
    ..This report summarizes the causes, clinical features, and outcomes from the first 300 patients enrolled...
  27. doi request reprint Noninvasive assessment of liver fibrosis and portal hypertension with transient elastography
    Don C Rockey
    Division of Digestive and Liver Diseases, University of Texas Southwestern Medical Center, Dallas, Texas, USA
    Gastroenterology 134:8-14. 2008
    ..To the extent that transient elastography is able to measure "liver stiffness," which is proportional to the degree of liver fibrosis, this technique holds great promise...
  28. ncbi request reprint Early colonoscopy for acute lower GI bleeding predicts shorter hospital stay: a retrospective study of experience in a single center
    Nathan Schmulewitz
    Gastroenterology Division, Duke Liver Center, Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA
    Gastrointest Endosc 58:841-6. 2003
    ..It is our hypothesis that clinical factors, such as comorbidity, hemodynamic instability, and timing of colonoscopy, are associated with hospital lengths of stay...
  29. ncbi request reprint Urgent colonoscopy for evaluation and management of acute lower gastrointestinal hemorrhage: a randomized controlled trial
    Bryan T Green
    Division of Gastroenterology, Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA
    Am J Gastroenterol 100:2395-402. 2005
    ..We hypothesized that early intervention in patients with lower gastrointestinal bleeding (LGIB) would improve outcomes and therefore conducted a prospective randomized study comparing urgent colonoscopy to standard care...
  30. doi request reprint Portal hypertensive gastropathy: a review
    Raul Cubillas
    Department of Internal Medicine, Division of Digestive and Liver Diseases, University of Texas Southwestern Medical Center, Dallas, TX, USA
    Liver Int 30:1094-102. 2010
    ..Further studies are needed to clarify the role of PHG in suspected chronic gastrointestinal bleeding...
  31. ncbi request reprint Adenovirus-mediated gene transfer to nonparenchymal cells in normal and injured liver
    Qing Yu
    Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA
    Am J Physiol Gastrointest Liver Physiol 282:G565-72. 2002
    ..This work implies that, to achieve comparable gene expression in the injured liver, higher adenoviral titers may be required, an important consideration as gene therapy in disease states is considered...
  32. ncbi request reprint Clinical utilization of digital rectal examination and fecal occult blood testing upon hospital admission
    Charles D Scales
    Division of Gastroenterology, Department of Medicine, Duke Clinical Research Institute, Duke University Medical Center, Durham, NC, USA
    J Clin Gastroenterol 40:913-8. 2006
    ..The objective of our investigation was to examine the clinical utilization of digital rectal examination (DRE) and fecal occult blood testing (FOBT) at hospital admission...
  33. pmc Divergent transforming growth factor-beta signaling in hepatic stellate cells after liver injury: functional effects on ECE-1 regulation
    Al Karim Khimji
    Department of Internal Medicine, UT Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390, USA
    Am J Pathol 173:716-27. 2008
    ..We speculate that TGF-beta signaling proceeds through differential signaling pathways depending on the mechanism of liver injury that leads to stellate cell activation...
  34. ncbi request reprint Gastrointestinal bleeding
    Don C Rockey
    Division of Digestive and Liver Diseases, University of Texas Southwestern Medical Center, Dallas, 75390 8887, USA
    Gastroenterol Clin North Am 34:581-8. 2005
    ....
  35. pmc Endothelin antagonism in portal hypertensive mice: implications for endothelin receptor-specific signaling in liver disease
    Hong Qiang Feng
    Division of Digestive and Liver Diseases, The University of Texas, Southwestern Medical Center, Dallas, TX 75390 8887, USA
    Am J Physiol Gastrointest Liver Physiol 297:G27-33. 2009
    ..The data imply a relationship between hepatic fibrogenesis or fibrosis and vasomotor responses...
  36. ncbi request reprint The effect of a low-carbohydrate, ketogenic diet on nonalcoholic fatty liver disease: a pilot study
    David Tendler
    Division of Gastroenterology, Department of Medicine, Duke University Health System, Durham, NC, USA
    Dig Dis Sci 52:589-93. 2007
    ..02) inflammatory grade (P=.02), and fibrosis (P=.07). Six months of a low-carbohydrate, ketogenic diet led to significant weight loss and histologic improvement of fatty liver disease. Further research is into this approach is warranted...
  37. ncbi request reprint Standards for gastroenterologists for performing and interpreting diagnostic computed tomographic colonography
    Don C Rockey
    University of Texas Southwestern Medical Center, Division of Digestive and Liver Diseases, Dallas, Texas, USA
    Gastroenterology 133:1005-24. 2007
  38. doi request reprint Effect of the nitric oxide donor V-PYRRO/NO on portal pressure and sinusoidal dynamics in normal and cirrhotic mice
    Claire Edwards
    Department of Medicine, Duke University Medical Center, Durham, NC, USA
    Am J Physiol Gastrointest Liver Physiol 294:G1311-7. 2008
    ..As the potential of this or other similar compounds for treatment of portal hypertension is evaluated, effects on the systemic vasculature will also need to be considered...
  39. doi request reprint Using capsule endoscopy to identify GI tract lesions in cirrhotic patients with portal hypertension and chronic anemia
    Karen R Canlas
    Division of Gastroenterology and Hepatology, Duke University Medical Center, Durham, NC 27705, USA
    J Clin Gastroenterol 42:844-8. 2008
    ..We aimed to evaluate the ability of capsule endoscopy (CE) to detect small intestine (SI) lesions, especially SI varices, in patients with intrahepatic cirrhosis, portal hypertension (PHTN), and chronic anemia...
  40. doi request reprint Correlation of FIBROSpect II with histologic and morphometric evaluation of liver fibrosis in chronic hepatitis C
    Keyur Patel
    Division of Gastroenterology, Duke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina 27705, USA
    Clin Gastroenterol Hepatol 6:242-7. 2008
    ..We hypothesized that a noninvasive test of liver fibrosis can accurately stage liver fibrosis. We prospectively evaluated the FIBROSpect II (FSII) biomarker panel versus pathology assessment and a quantitative measure of fibrosis...
  41. ncbi request reprint Antifibrotic therapy in chronic liver disease
    Don C Rockey
    Department of Cell Biology, Duke University Medical Center, Durham, North Carolina, USA
    Clin Gastroenterol Hepatol 3:95-107. 2005
    ..This article emphasizes mechanisms underlying fibrogenesis, and reviews current antifibrotic therapies as well as potential future approaches...
  42. ncbi request reprint Acute HCV: the early bird catches the virus
    Andrew J Muir
    Gastroenterology 122:1176-7; discussion 1177-8. 2002
  43. ncbi request reprint Dose-dependent inhibition of hepatic fibrosis in mice by a TGF-beta soluble receptor: implications for antifibrotic therapy
    Yutaka Yata
    Liver Center and Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA
    Hepatology 35:1022-30. 2002
    ..Such findings have major translational implications for therapeutic strategies aimed at TGF-beta...
  44. ncbi request reprint Predictors of endoscopic and laboratory evaluation of iron deficiency anemia in hospitalized patients
    George N Ioannou
    Department of Medicine and Division of Gastroenterology, Veterans Affairs Puget Sound Health Care System, Seattle, WA, USA
    South Med J 100:976-84. 2007
    ..Many hospitalized anemic patients do not undergo appropriate evaluation. We hypothesized that specific clinical variables were likely to be important in triggering evaluation for iron deficiency anemia...
  45. ncbi request reprint Obscure gastrointestinal bleeding
    Sauyu Lin
    Division of Gastroenterology, Duke University Medical Center, Durham, NC, USA
    Gastroenterol Clin North Am 34:679-98. 2005
    ..Treatment for vascularectasias, the most common cause of obscure GI bleeding, is currently inadequate,and typically requires a combination of multiple management approaches...
  46. ncbi request reprint Virtual colonoscopy to screen for colorectal cancer
    Don C Rockey
    N Engl J Med 350:1148-50; author reply 1148-50. 2004
  47. ncbi request reprint Viral hepatitis C
    Alastair D Smith
    Lancet 363:661. 2004
  48. ncbi request reprint Acute gastrointestinal bleeding
    Bryan T Green
    Gastroenterology Division and Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA
    Semin Gastrointest Dis 14:44-65. 2003
    ..Surgery offers the opportunity for definitive therapy at the cost of higher morbidity. At this time, the approach to evaluation and management should be based on the specific clinical situation and available local expertise...
  49. ncbi request reprint Therapy for primary prophylaxis of varices: and, the winner is...?
    Ala I Sharara
    American University of Beirut, and Duke University Medical Centers, Durham, NC, USA
    Hepatology 37:473-5; discussion 475-6. 2003
  50. ncbi request reprint Prospective evaluation of a clinical guideline for the diagnosis and management of iron deficiency anemia
    George N Ioannou
    Division of Gastroenterology, University of Washington and Health Services Research and Development, Puget Sound Veterans Affairs Health Care System, Seattle, Washington, USA
    Am J Med 113:281-7. 2002
    ..We examined the effect of introducing an evidence-based clinical guideline on the diagnosis and evaluation of iron deficiency anemia...
  51. ncbi request reprint Iron deficiency and gastrointestinal malignancy: a population-based cohort study
    George N Ioannou
    Department of Medicine and Division of Gastroenterology, University of Washington Medical Center, Seattle, Washington 98108, USA
    Am J Med 113:276-80. 2002
    ..We investigated whether iron deficiency, with or without anemia, is associated with an increased likelihood of gastrointestinal malignancy...
  52. ncbi request reprint Treatment of acute hepatitis C with interferon alfa-2b
    Andrew Muir
    N Engl J Med 346:1091-2. 2002
  53. pmc Leptin in hepatic fibrosis: evidence for increased collagen production in stellate cells and lean littermates of ob/ob mice
    Neeraj K Saxena
    Hepatology Section, University of Maryland School of Medicine, Baltimore, MD 21201 1595, USA
    Hepatology 35:762-71. 2002
    ..Up-regulation of leptin signaling in liver injury could contribute to enhanced fibrogenesis, particularly in states in which leptin levels are high...
  54. ncbi request reprint Diffuse colonic hemangiomatosis
    Brian M Dobozi
    Division of Gastroenterology, Duke University Medical Center, Durham, North Carolina, USA
    Gastrointest Endosc 60:799. 2004
  55. ncbi request reprint CT colonography: false-negative interpretations
    Taral Doshi
    Department of Radiology, University of Chicago, Chicago, IL 60637, USA
    Radiology 244:165-73. 2007
    ..To retrospectively evaluate if false-negative interpretations at computed tomographic (CT) colonography are due to observer error...
  56. ncbi request reprint Stellate cell/HCV interactions in hepatic fibrosis
    Don C Rockey
    Gastroenterology 129:2117-8. 2005
  57. ncbi request reprint Colonoscopic withdrawal times and adenoma detection
    Samir Gupta
    N Engl J Med 356:1174; author reply 1174. 2007
  58. ncbi request reprint Colon cancer screening, polyp size, and CT colonography: making sense of it all?
    Don C Rockey
    Gastroenterology 131:2006-9. 2006
  59. ncbi request reprint Hepatic fibrosis 2006: report of the Third AASLD Single Topic Conference
    Scott L Friedman
    Division of Liver Diseases, Mount Sinai School of Medicine, New York, NY 10029, USA
    Hepatology 45:242-9. 2007
    ....
  60. ncbi request reprint Prospective comparison of patient experience with colon imaging tests
    Hayden B Bosworth
    Center for Health Services Research in Primary Care, Durham VA Medical Center, Durham, NC, USA
    Am J Med 119:791-9. 2006
    ..We examined differences in patient experience with colon imaging tests and whether they varied with gender, age, and race...
  61. ncbi request reprint Regulation of peroxisome proliferator-activated receptor-gamma in liver fibrosis
    Liu Yang
    Department of Cell Biology, Duke University Medical Center, Durham, NC, USA
    Am J Physiol Gastrointest Liver Physiol 291:G902-11. 2006
    ..The data highlight a critical role for PPARgamma during in vivo fibrogenesis and emphasize the importance of the PPARgamma pathway in stellate cells during liver injury...
  62. ncbi request reprint A crucial role for GRK2 in regulation of endothelial cell nitric oxide synthase function in portal hypertension
    Songling Liu
    Department of Cell Biology, Duke University Medical Center, Durham, North Carolina 27710, USA
    Nat Med 11:952-8. 2005
    ..Thus, an important mechanism underlying impaired activity of eNOS in injured sinusoidal endothelial cells is defective phosphorylation of Akt caused by overexpression of GRK2 after injury...
  63. ncbi request reprint Proton pump inhibitors in acute peptic ulcer bleeding
    Don C Rockey
    Gastroenterology 129:756-7. 2005
  64. ncbi request reprint Colon imaging: computed tomographic colonography
    Don C Rockey
    Duke University Medical Center, Durham, NC 27710, USA
    Clin Gastroenterol Hepatol 3:S37-41. 2005
    ..It is clear that CTC has great promise, but also that many questions about its use remain to be answered...
  65. ncbi request reprint De-novo cholangiocarcinoma in the setting of recurrent primary sclerosing cholangitis following liver transplant
    Michael A Heneghan
    Division of Gastroenterology, Duke University Medical Center, Durham, NC, USA
    Am J Transplant 3:634-8. 2003
    ..No viable tumor was identified in the explanted liver. This case establishes that long-term complications associated with PSC and biliary-enteric surgery such as CCA may become apparent in new grafts post-transplant...
  66. doi request reprint Managing anticoagulation and antiplatelet medications in GI endoscopy: a survey comparing the East and the West
    Sun Young Lee
    Department of Internal Medicine, Konkuk University School of Medicine, Seoul, Korea
    Gastrointest Endosc 67:1076-81. 2008
    ..Anticoagulation and antiplatelet medications may potentiate GI bleeding, and their use may lead to an increased need for a GI endoscopy. We hypothesized that there might be different practice patterns among international endoscopists...

Research Grants31

  1. PATHOGENESIS OF HEPATIC FIBROSIS AND PORTAL HYPERTENSION
    Don Rockey; Fiscal Year: 2004
    ..These studies have direct relevance to human liver disease and will lead to new approaches for the treatment of hepatic fibrosis and portal hypertension as well as other forms of fibrosing injury. ..
  2. Regulation of Stellate Cell Contractility
    Don Rockey; Fiscal Year: 2007
    ..Physiologic endpoints will be an important focus. The proposed studies will shed light on the molecular basis of stellate cell contractility and moreover have direct relevance to human liver disease. ..
  3. PATHOGENESIS OF HEPATIC FIBROSIS AND PORTAL HYPERTENSION
    Don Rockey; Fiscal Year: 2007
    ..These studies have direct relevance to human liver disease and will lead to new approaches for the treatment of hepatic fibrosis and portal hypertension as well as other forms of fibrosing injury. ..
  4. PATHOGENESIS OF HEPATIC FIBROSIS AND PORTAL HYPERTENSION
    Don Rockey; Fiscal Year: 2009
    ..These studies have direct relevance to human liver disease and will lead to new approaches for the treatment of hepatic fibrosis and portal hypertension as well as other forms of fibrosing injury. ..
  5. Nitric Oxide and the Cellular Pathogenesis of Portal Hypertension
    Don C Rockey; Fiscal Year: 2010
    ..This leads to intestinal bleeding and severe clinical consequences. This proposal aims to understand the cause of elevated resistance to blood flow and would shed light on potential treatments for this problem. ..
  6. PATHOGENESIS OF HEPATIC FIBROSIS AND PORTAL HYPERTENSION
    Don Rockey; Fiscal Year: 1999
    ..These studies have direct relevance to human liver disease and are likely to lead to new approaches for the treatment of portal hypertension, hepatic fibrosis and possibly other forms of fibrosing injury. ..
  7. PROSPECTIVE COMPARISON OF COLONIC IMAGING TEST
    Don Rockey; Fiscal Year: 2001
    ..The information gained from this study is expected to form the basis for national policy and decision making with reward to colonic imaging tests. ..
  8. Nitric Oxide and the Liver
    Don Rockey; Fiscal Year: 2003
    ..The dates of the entire AASLD scientific meeting are November 3rd to November 5th. The participants will be invited speakers and attendees of the annual 2002 AASLD meeting. ..
  9. PATHOGENESIS OF HEPATIC FIBROSIS AND PORTAL HYPERTENSION
    Don C Rockey; Fiscal Year: 2010
    ..These studies have direct relevance to human liver disease and will lead to new approaches for the treatment of hepatic fibrosis and portal hypertension as well as other forms of fibrosing injury. ..