ROBERT ROCK

Summary

Affiliation: University of Minnesota
Country: USA

Publications

  1. pmc CB2 receptor agonists protect human dopaminergic neurons against damage from HIV-1 gp120
    Shuxian Hu
    Center for Infectious Diseases and Microbiology Translational Research, Division of Infectious Diseases and International Medicine, Department of Medicine, University of Minnesota Medical School, Minneapolis, Minnesota, United States of America
    PLoS ONE 8:e77577. 2013
  2. ncbi request reprint Potentiation of HIV-1 expression in microglial cells by nicotine: involvement of transforming growth factor-beta 1
    R Bryan Rock
    Center for Infectious Diseases and Microbiology Translational Research, Division of Infectious Diseases and International Medicine, Department of Medicine, University of Minnesota Medical School, Minneapolis, MN 55455, USA
    J Neuroimmune Pharmacol 3:143-9. 2008
  3. pmc Central nervous system tuberculosis: pathogenesis and clinical aspects
    R Bryan Rock
    Center for Infectious Diseases and Microbiology Translational Research, and Department of Medicine, University of Minnesota Medical School, Minneapolis, Minnesota, USA
    Clin Microbiol Rev 21:243-61, table of contents. 2008
  4. ncbi request reprint Human neural precursor cells express functional kappa-opioid receptors
    Wen S Sheng
    The Center for Infectious Diseases and Microbiology Translational Research, Department of Medicine, University of Minnesota Medical School, Minneapolis, MN 55455, USA
    J Pharmacol Exp Ther 322:957-63. 2007
  5. ncbi request reprint Mycobacterium tuberculosis-induced cytokine and chemokine expression by human microglia and astrocytes: effects of dexamethasone
    R Bryan Rock
    Neuroimmunobiology and Host Defense Laboratory, Minneapolis Medical Research Foundation, MN 55455, USA
    J Infect Dis 192:2054-8. 2005
  6. pmc Extrapulmonary Tuberculosis among Somalis in Minnesota
    R Bryan Rock
    University of Minnesota Medical School, Minneapolis, Minnesota 55415, USA
    Emerg Infect Dis 12:1434-6. 2006
  7. ncbi request reprint WIN55,212-2-mediated inhibition of HIV-1 expression in microglial cells: involvement of cannabinoid receptors
    R Bryan Rock
    Center for Infectious Diseases and Microbiology Translational Research and Department of Medicine, University of Minnesota Medical School, Minneapolis, MN, USA
    J Neuroimmune Pharmacol 2:178-83. 2007
  8. ncbi request reprint Role of nitric oxide in defense of the central nervous system against Mycobacterium tuberculosis
    Michael R Olin
    Veterinary Population Medicine, Veterinary Teaching Hospital, University of Minnesota, St Paul, USA
    J Infect Dis 198:886-9. 2008

Collaborators

Detail Information

Publications9

  1. pmc CB2 receptor agonists protect human dopaminergic neurons against damage from HIV-1 gp120
    Shuxian Hu
    Center for Infectious Diseases and Microbiology Translational Research, Division of Infectious Diseases and International Medicine, Department of Medicine, University of Minnesota Medical School, Minneapolis, Minnesota, United States of America
    PLoS ONE 8:e77577. 2013
    ..These data suggest that synthetic cannabinoids are capable of protecting human dopaminergic neurons from gp120 in a variety of ways, acting principally through the CB2 receptors and microglia. ..
  2. ncbi request reprint Potentiation of HIV-1 expression in microglial cells by nicotine: involvement of transforming growth factor-beta 1
    R Bryan Rock
    Center for Infectious Diseases and Microbiology Translational Research, Division of Infectious Diseases and International Medicine, Department of Medicine, University of Minnesota Medical School, Minneapolis, MN 55455, USA
    J Neuroimmune Pharmacol 3:143-9. 2008
    ..We also found that nicotine robustly altered the gene expression profile of HIV-1-infected microglia and that the transforming growth factor-beta1 is involved in the enhanced expression of HIV-1 by nicotine...
  3. pmc Central nervous system tuberculosis: pathogenesis and clinical aspects
    R Bryan Rock
    Center for Infectious Diseases and Microbiology Translational Research, and Department of Medicine, University of Minnesota Medical School, Minneapolis, Minnesota, USA
    Clin Microbiol Rev 21:243-61, table of contents. 2008
    ..tuberculosis, to discuss certain epidemiological, clinical, diagnostic, and therapeutic aspects of CNS tuberculosis, and also to underscore the many unmet needs in this important field...
  4. ncbi request reprint Human neural precursor cells express functional kappa-opioid receptors
    Wen S Sheng
    The Center for Infectious Diseases and Microbiology Translational Research, Department of Medicine, University of Minnesota Medical School, Minneapolis, MN 55455, USA
    J Pharmacol Exp Ther 322:957-63. 2007
    ..Taken together, the results of this study suggest that activation of KORs alters functional properties of NPCs/NSCs that are relevant to human brain development and repair...
  5. ncbi request reprint Mycobacterium tuberculosis-induced cytokine and chemokine expression by human microglia and astrocytes: effects of dexamethasone
    R Bryan Rock
    Neuroimmunobiology and Host Defense Laboratory, Minneapolis Medical Research Foundation, MN 55455, USA
    J Infect Dis 192:2054-8. 2005
    ....
  6. pmc Extrapulmonary Tuberculosis among Somalis in Minnesota
    R Bryan Rock
    University of Minnesota Medical School, Minneapolis, Minnesota 55415, USA
    Emerg Infect Dis 12:1434-6. 2006
    ..The presence of these recent immigrants substantially affects the local epidemiology and clinical manifestation of tuberculosis...
  7. ncbi request reprint WIN55,212-2-mediated inhibition of HIV-1 expression in microglial cells: involvement of cannabinoid receptors
    R Bryan Rock
    Center for Infectious Diseases and Microbiology Translational Research and Department of Medicine, University of Minnesota Medical School, Minneapolis, MN, USA
    J Neuroimmune Pharmacol 2:178-83. 2007
    ....
  8. ncbi request reprint Role of nitric oxide in defense of the central nervous system against Mycobacterium tuberculosis
    Michael R Olin
    Veterinary Population Medicine, Veterinary Teaching Hospital, University of Minnesota, St Paul, USA
    J Infect Dis 198:886-9. 2008
    ..This study underscores the importance of nitric oxide in defense against TBM and suggests that iNOS(-/-) mice are an appropriate model for human TBM...

Research Grants5

  1. Nicotine in HIV-1 and Mycobacterium tuberculosis Neuropathogenesis
    ROBERT ROCK; Fiscal Year: 2007
    ..abstract_text> ..
  2. Protective Effects of Cannabinoids in HIV Neuropathogenesis
    ROBERT ROCK; Fiscal Year: 2009
    ....
  3. Protective Effects of Cannabinoids in HIV Neuropathogenesis
    ROBERT BRYAN ROCK; Fiscal Year: 2010
    ....