Research Topics
Species | Michael J RockSummaryAffiliation: University of Wisconsin Country: USA Publications
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Detail Information
Publications
Newborn screening for cystic fibrosis in Wisconsin: nine-year experience with routine trypsinogen/DNA testingMichael J Rock
Department of Pediatrics and State Laboratory of Hygiene, University of Wisconsin, Madison, Wisconsin 53792, USA
J Pediatr 147:S73-7. 2005..To describe the development and follow-up confirmatory results of the routine cystic fibrosis (CF) newborn screening (NBS) program in Wisconsin...
Factors accounting for a missed diagnosis of cystic fibrosis after newborn screeningMichael J Rock
School of Medicine and Public Health, University of Wisconsin Madison, Madison, Wisconsin 53792, USA
Pediatr Pulmonol 46:1166-74. 2011....
Newborn screening for cystic fibrosisMichael J Rock
Division of Pediatric Pulmonology, University of Wisconsin Hospital and Clinics, 600 Highland Avenue, Room K4 946, Madison, WI 53792, USA
Clin Chest Med 28:297-305. 2007..Studies have demonstrated benefits of newborn screening in the areas of nutrition, cognitive function, pulmonary function, and survival...
Evidence on improved outcomes with early diagnosis of cystic fibrosis through neonatal screening: enough is enough!Philip M Farrell
Department of Pediatrics, Biostatistics Medical Informatics, Radiology, Nutritional Sciences, and the State Laboratory of Hygiene, University of Wisconsin, Madison, WI 53706 1532, USA
J Pediatr 147:S30-6. 2005..To generate and examine evidence in support of diagnosing cystic fibrosis (CF) early through newborn screening (NBS)...
Preventing early, prolonged vitamin E deficiency: an opportunity for better cognitive outcomes via early diagnosis through neonatal screeningRebecca L Koscik
Department of Biostatistics Medical Informatics, Nutritional Sciences, and Pediatrics, University of Wisconsin, Madison, WI 53792, USA
J Pediatr 147:S51-6. 2005..To evaluate whether early diagnosis of cystic fibrosis (CF) through newborn screening (NBS) and early vitamin E status are associated with cognitive function...
Bronchopulmonary disease in children with cystic fibrosis after early or delayed diagnosisPhilip M Farrell
Department of Pediatrics, University of Wisconsin Medical School, Madison, WI 53706 1532, USA
Am J Respir Crit Care Med 168:1100-8. 2003..Although CF neonatal screening provides a potential opportunity for better pulmonary outcomes, it appears that respiratory infections and pancreatic status are the dominant factors in pulmonary prognosis...
Quality of life of children with cystic fibrosisRebecca L Koscik
Department of Biostatistics and Medical Informatics, Madison, WI 53792, USA
J Pediatr 147:S64-8. 2005....
Regional differences in the evolution of lung disease in children with cystic fibrosisZhanhai Li
Department of Pediatrics, University of Wisconsin Madison, Madison, Wisconsin 53792 9988, USA
Pediatr Pulmonol 47:635-40. 2012..A variety of potential explanations such as aspiration episodes may be clinically relevant and provide insights regarding therapies...
Longitudinal development of mucoid Pseudomonas aeruginosa infection and lung disease progression in children with cystic fibrosisZhanhai Li
Department of Pediatrics, University of Wisconsin, Madison 53705-2221, USA
JAMA 293:581-8. 2005..Antibody titers, cough scores, and chest radiographs are early signs of nonmucoid P aeruginosa and especially mucoid P aeruginosa stages...
Newborn screening for cystic fibrosis: parents' preferences regarding counseling at the time of infants' sweat testAudrey Tluczek
School of Nursing, University of Wisconsin Madison, 600 Highland Ave, Madison, Wisconsin 53792, USA
J Genet Couns 15:277-91. 2006..Counseling that matched parents preferences reduced parents' distress while mismatched counseling tended to increase parents' worry about their infant...
Relationships among health-related quality of life, pulmonary health, and newborn screening for cystic fibrosisAudrey Tluczek
School of Nursing, University of Wisconsin, Madison, WI 53792, USA
Chest 140:170-7. 2011..The objective of this study was to examine relationships between pulmonary health and health-related quality of life (HRQOL) in patients with cystic fibrosis (CF) evaluated longitudinally in the Wisconsin Newborn Screening Project...
Psychosocial risk associated with newborn screening for cystic fibrosis: parents' experience while awaiting the sweat-test appointmentAudrey Tluczek
Department of Psychiatry, University of Wisconsin, 6001 Research Park Blvd, Madison, WI 53719 1179, USA
Pediatrics 115:1692-703. 2005..The psychosocial effects on parents of infants with abnormal results in cystic fibrosis (CF) newborn screening (NBS) that uses genetic testing remain unclear...
Cognitive function of children with cystic fibrosis: deleterious effect of early malnutritionRebecca L Koscik
Department of Biostatistics/Medical Informatics, University of Wisconsin, Madison 53706-1532, USA
Pediatrics 113:1549-58. 2004....
Growth and pulmonary outcomes during the first 2 y of life of breastfed and formula-fed infants diagnosed with cystic fibrosis through the Wisconsin Routine Newborn Screening ProgramSarah A Jadin
Department of Nutritional Sciences, College of Agriculture and Life Sciences, University of Wisconsin, Madison, WI 53706, USA
Am J Clin Nutr 93:1038-47. 2011..The optimal feeding (breast milk, formula, or a combination) for infants with cystic fibrosis (CF) is unknown. Recommendations from the CF Foundation are based on limited data...
Longitudinal pulmonary status of cystic fibrosis children with meconium ileusZhanhai Li
Department of Pediatrics, University of Wisconsin, Madison, Wisconsin, USA
Pediatr Pulmonol 38:277-84. 2004..In conclusion, MI children have worse lung function and more obstructive lung disease than those without MI. Such abnormalities are accompanied by reduced lung volume. MI is a distinct CF phenotype with more severe pulmonary dysfunction...
The sensitivity of lung disease surrogates in detecting chest CT abnormalities in children with cystic fibrosisDon B Sanders
Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA
Pediatr Pulmonol 47:567-73. 2012..Quantitative chest radiography scores are useful in detecting mild lung disease, but whether they are sensitive to the presence of CT scan abnormalities has not been evaluated...
Comparing age of cystic fibrosis diagnosis and treatment initiation after newborn screening with two common strategiesDon B Sanders
Department of Pediatrics, University of Wisconsin, Madison, WI, United States
J Cyst Fibros 11:150-3. 2012..Newborn screening (NBS) for CF has become widespread, although there are multiple strategies. Little is known about outcomes such as age of diagnosis after different NBS methods...
Guidelines for diagnosis of cystic fibrosis in newborns through older adults: Cystic Fibrosis Foundation consensus reportPhilip M Farrell
Department of Pediatrics and Population Health Sciences, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA
J Pediatr 153:S4-S14. 2008..Their recommendations, presented herein, involve a combination of clinical presentation, laboratory testing, and genetics to confirm a diagnosis of CF...
Association between mucoid Pseudomonas infection and bronchiectasis in children with cystic fibrosisPhilip M Farrell
Department of Pediatrics, University of Wisconsin, Madison, Wis, USA
Radiology 252:534-43. 2009..To correlate the severity of bronchiectasis in children with cystic fibrosis with clinical and microbiologic variables in order to clarify risk factors for the development of irreversible lung disease...
Longitudinal evaluation of bronchopulmonary disease in children with cystic fibrosisPhilip M Farrell
Department of Pediatrics, University of Wisconsin, Madison, Wisconsin, USA
Pediatr Pulmonol 36:230-40. 2003..Our results also suggest that bronchiectasis and other radiographic evidence of chronic infection are apparent prior to airways obstruction in young CF patients...
Respiratory infections with Pseudomonas aeruginosa in children with cystic fibrosis: early detection by serology and assessment of risk factorsSusan E H West
Department of Pathobiological Sciences and School of Veterinary Medicine, University of Wisconsin, 1300 University Ave, Madison, WI 53706, USA
JAMA 287:2958-67. 2002..The longitudinal monitoring of P aeruginosa antibody titers, in concert with WCXR score, should facilitate diagnosis and treatment of P aeruginosa pulmonary infections in young children with CF...
Children with cystic fibrosis produce an immune response against exoenzyme S, a type III cytotoxin of Pseudomonas aeruginosaBruce Banwart
J Infect Dis 185:269-70. 2002
