Research Topics
| Malcolm RobinsonSummaryAffiliation: University of Oklahoma Health Sciences Center Country: USA Publications
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Detail Information
Publications
Review article: current perspectives on hypergastrinaemia and enterochromaffin-like-cell hyperplasiaM Robinson
University of Oklahoma College of Medicine, Oklahoma Foundation for Digestive Research, Oklahoma City, USA
Aliment Pharmacol Ther 13:5-10. 1999..Furthermore, neither animal nor human data obtained with rabeprazole suggest a significant risk for neoplastic changes secondary to hypergastrinaemia...
Proton pump inhibitors: update on their role in acid-related gastrointestinal diseasesM Robinson
University of Oklahoma College of Medicine, Oklahoma City, Oklahoma, USA
Int J Clin Pract 59:709-15. 2005..New data, in addition, highlight differences in PPI metabolism that may both affect efficacy and predispose patients to drug-drug interactions. PPI selection should involve the awareness of these issues...
Review article: pH, healing and symptom relief with rabeprazole treatment in acid-related disordersM Robinson
Oklahoma Foundation for Digestive Research, University of Oklahoma, Oklahoma City, OK 74104, USA
Aliment Pharmacol Ther 20:30-7. 2004....
Review article: the pharmacodynamics and pharmacokinetics of proton pump inhibitors--overview and clinical implicationsM Robinson
Oklahoma Foundation for Digestive Research, University of Oklahoma, Oklahoma City, OK 73104, USA
Aliment Pharmacol Ther 20:1-10. 2004..A brief overview presents the pharmacodynamics and pharmacokinetics of the proton pump inhibitors with particular attention paid to rabeprazole, one of the newer drugs in its class...
Clinical pharmacology of proton pump inhibitors: what the practising physician needs to knowMalcolm Robinson
Department of Medicine, Oklahoma Foundation for Digestive Research, University of Oklahoma College of Medicine, Oklahoma City, Oklahoma, USA
Drugs 63:2739-54. 2003..g. increased digoxin absorption or inability to absorb ketoconazole)...
Onset of symptom relief with rabeprazole: a community-based, open-label assessment of patients with erosive oesophagitisM Robinson
Oklahoma Foundation for Digestive Research, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104 5022, USA
Aliment Pharmacol Ther 16:445-54. 2002..In numerous clinical trials, proton pump inhibitors have demonstrated potent acid suppression and healing of erosive oesophagitis, as well as successful symptom relief for the entire spectrum of gastro-oesophageal reflux disease...
Dyspepsia: challenges in diagnosis and selection of treatmentM Robinson
University of Oklahoma College of Medicine, Oklahoma Foundation for Digestive Research, Oklahoma City 73104 5022, USA
Clin Ther 23:1130-44; discussion 1129. 2001..Despite considerable study, the pathophysiology of dyspepsia remains obscure. This and other factors have impeded development of precise and effective treatment strategies...
New-generation proton pump inhibitors: overcoming the limitations of early-generation agentsM Robinson
Department of Medicine, University of Oklahoma, Oklahoma City, USA
Eur J Gastroenterol Hepatol 13:S43-7. 2001..Unlike esomeprazole, the use of rabeprazole is not complicated by clinically significant drug-drug interactions of the type that have been reported for omeprazole and the wide range of medications metabolized by CYP 2C19...
Control of nocturnal gastric acidity: a role for low dose bedtime ranitidine to supplement daily omeprazoleMalcolm Robinson
Oklahoma Foundation for Digestive Research, University of Oklahoma, Health Sciences Center, Oklahoma City, USA
Dig Dis Sci 47:265-73. 2002....
Time esophageal pH < 4 overestimates the prevalence of pathologic esophageal reflux in subjects with gastroesophageal reflux disease treated with proton pump inhibitorsLauren B Gerson
Stanford University School of Medicine, Stanford, CA, USA
BMC Gastroenterol 8:15. 2008..A Stanford University study reported that in asymptomatic GERD patients who were being treated with a proton pump inhibitor (PPI), 50% had pathologic esophageal acid exposure...
Measurement of meal-stimulated gastric acid secretion by in vivo gastric autotitrationJerry D Gardner
Science for Organizations, Inc, Chatham, New Jersey 07928, USA
J Appl Physiol 92:427-34. 2002..72; P = 0.0001). Thus intragastric autotitration is a convenient, reproducible method for measuring gastric acid secretion after ingestion of a solid meal and offers several advantages over manual intragastric titration...
