Jennifer G Robinson

Summary

Affiliation: University of Iowa
Country: USA

Publications

  1. doi request reprint Meta-analysis of comparison of effectiveness of lowering apolipoprotein B versus low-density lipoprotein cholesterol and nonhigh-density lipoprotein cholesterol for cardiovascular risk reduction in randomized trials
    Jennifer G Robinson
    University of Iowa, Iowa City, IA, USA
    Am J Cardiol 110:1468-76. 2012
  2. ncbi request reprint Management of familial hypercholesterolemia: a review of the recommendations from the National Lipid Association Expert Panel on Familial Hypercholesterolemia
    Jennifer G Robinson
    Departments of Epidemilogy and Medicine, Prevention Intervention Center, College of Public Health, University of Iowa, Iowa City, Iowa, USA
    J Manag Care Pharm 19:139-49. 2013
  3. doi request reprint Counterpoint: Low-Density Lipoprotein Cholesterol Targets Are Not Needed in Lipid Treatment Guidelines
    Jennifer G Robinson
    From the Department of Epidemiology, College of Public Health, University of Iowa, Iowa City J G R and Department of Primary Care and Public Health, Imperial College London, London, United Kingdom K R
    Arterioscler Thromb Vasc Biol 36:586-90. 2016
  4. doi request reprint Atherosclerosis stabilization with PCSK-9 inhibition: An evolving concept for cardiovascular prevention
    Jennifer G Robinson
    University of Iowa, USA Electronic address
    Atherosclerosis 243:593-7. 2015
  5. doi request reprint Starting primary prevention earlier with statins
    Jennifer G Robinson
    Department of Epidemiology, University of Iowa, Iowa City, Iowa Department of Medicine, University of Iowa, Iowa City, Iowa Prevention Intervention Center, College of Public Health, University of Iowa, Iowa City, Iowa Electronic address
    Am J Cardiol 114:1437-42. 2014
  6. pmc Self-perceived physical health predicts cardiovascular disease incidence and death among postmenopausal women
    Nazmus Saquib
    Stanford Prevention Research Center, Department of Medicine, Stanford University, Stanford, CA, USA
    BMC Public Health 13:468. 2013
  7. pmc Efficacy and safety of alirocumab, a fully human PCSK9 monoclonal antibody, in high cardiovascular risk patients with poorly controlled hypercholesterolemia on maximally tolerated doses of statins: rationale and design of the ODYSSEY COMBO I and II trials
    Helen M Colhoun
    University of Dundee, Dundee, Scotland DD2 4BF, UK
    BMC Cardiovasc Disord 14:121. 2014
  8. doi request reprint Curing atherosclerosis should be the next major cardiovascular prevention goal
    Jennifer G Robinson
    Departments of Epidemiology and Medicine, University of Iowa, Iowa City, Iowa Electronic address
    J Am Coll Cardiol 63:2779-85. 2014
  9. pmc Should We Use PPAR Agonists to Reduce Cardiovascular Risk?
    Jennifer G Robinson
    Departments of Epidemiology and Medicine, University of Iowa, Iowa City, IA 52242, USA
    PPAR Res 2008:891425. 2008
  10. doi request reprint 2013 ACC/AHA cholesterol guideline for reducing cardiovascular risk: what is so controversial?
    Jennifer G Robinson
    Departments of Epidemiology and Medicine, University of Iowa, 145 N Riverside Drive S455 CPHB, Iowa City, IA, 52242, USA
    Curr Atheroscler Rep 16:413. 2014

Collaborators

Detail Information

Publications71

  1. doi request reprint Meta-analysis of comparison of effectiveness of lowering apolipoprotein B versus low-density lipoprotein cholesterol and nonhigh-density lipoprotein cholesterol for cardiovascular risk reduction in randomized trials
    Jennifer G Robinson
    University of Iowa, Iowa City, IA, USA
    Am J Cardiol 110:1468-76. 2012
    ..For statins, apoB decreases added information to LDL cholesterol and non-HDL cholesterol decreases for predicting coronary heart disease but not stroke or overall cardiovascular disease risk decrease...
  2. ncbi request reprint Management of familial hypercholesterolemia: a review of the recommendations from the National Lipid Association Expert Panel on Familial Hypercholesterolemia
    Jennifer G Robinson
    Departments of Epidemilogy and Medicine, Prevention Intervention Center, College of Public Health, University of Iowa, Iowa City, Iowa, USA
    J Manag Care Pharm 19:139-49. 2013
    ..Utilization of published guidelines and the recommendations from the National Lipid Association will help to optimize the management of patients with FH...
  3. doi request reprint Counterpoint: Low-Density Lipoprotein Cholesterol Targets Are Not Needed in Lipid Treatment Guidelines
    Jennifer G Robinson
    From the Department of Epidemiology, College of Public Health, University of Iowa, Iowa City J G R and Department of Primary Care and Public Health, Imperial College London, London, United Kingdom K R
    Arterioscler Thromb Vasc Biol 36:586-90. 2016
    ..In the meantime, LDL-C thresholds rather than targets may aid in determining which patients might benefit from additional LDL-C-lowering therapy beyond statins. ..
  4. doi request reprint Atherosclerosis stabilization with PCSK-9 inhibition: An evolving concept for cardiovascular prevention
    Jennifer G Robinson
    University of Iowa, USA Electronic address
    Atherosclerosis 243:593-7. 2015
    ..The necessity of expensive lifetime treatment with PCSK-9 inhibitors could then be avoided in all but a small subset of patients who could benefit from longer treatment. ..
  5. doi request reprint Starting primary prevention earlier with statins
    Jennifer G Robinson
    Department of Epidemiology, University of Iowa, Iowa City, Iowa Department of Medicine, University of Iowa, Iowa City, Iowa Prevention Intervention Center, College of Public Health, University of Iowa, Iowa City, Iowa Electronic address
    Am J Cardiol 114:1437-42. 2014
    ..In conclusion, earlier initiation of statin therapy has the potential to have a large long-term impact on the heavy burden of cardiovascular disease in the aging populations. ..
  6. pmc Self-perceived physical health predicts cardiovascular disease incidence and death among postmenopausal women
    Nazmus Saquib
    Stanford Prevention Research Center, Department of Medicine, Stanford University, Stanford, CA, USA
    BMC Public Health 13:468. 2013
    ..Their relationships with CVD incidence are unclear. This study purpose was to test whether PCS and/or MCS were associated with CVD incidence and death...
  7. pmc Efficacy and safety of alirocumab, a fully human PCSK9 monoclonal antibody, in high cardiovascular risk patients with poorly controlled hypercholesterolemia on maximally tolerated doses of statins: rationale and design of the ODYSSEY COMBO I and II trials
    Helen M Colhoun
    University of Dundee, Dundee, Scotland DD2 4BF, UK
    BMC Cardiovasc Disord 14:121. 2014
    ..Alirocumab is a fully human monoclonal antibody to proprotein convertase subtilisin kexin type 9 (PCSK9) under investigation for treatment of hypercholesterolemia and reduction of cardiovascular events...
  8. doi request reprint Curing atherosclerosis should be the next major cardiovascular prevention goal
    Jennifer G Robinson
    Departments of Epidemiology and Medicine, University of Iowa, Iowa City, Iowa Electronic address
    J Am Coll Cardiol 63:2779-85. 2014
    ..Ultimately, this new paradigm will need to be evaluated in ASCVD outcomes trials. ..
  9. pmc Should We Use PPAR Agonists to Reduce Cardiovascular Risk?
    Jennifer G Robinson
    Departments of Epidemiology and Medicine, University of Iowa, Iowa City, IA 52242, USA
    PPAR Res 2008:891425. 2008
    ..It will be imperative to prove that future PPAR agonists not only prevent atherosclerotic events but also result in a net reduction on total cardiovascular events without significant noncardiovascular adverse effects with long-term use...
  10. doi request reprint 2013 ACC/AHA cholesterol guideline for reducing cardiovascular risk: what is so controversial?
    Jennifer G Robinson
    Departments of Epidemiology and Medicine, University of Iowa, 145 N Riverside Drive S455 CPHB, Iowa City, IA, 52242, USA
    Curr Atheroscler Rep 16:413. 2014
    ..Areas of controversy are discussed. ..
  11. doi request reprint Age, abdominal obesity, and baseline high-sensitivity C-reactive protein are associated with low-density lipoprotein cholesterol, non-high-density lipoprotein cholesterol, and apolipoprotein B responses to ezetimibe/simvastatin and atorvastatin in patient
    Jennifer G Robinson
    Department of Epidemiology and Medicine, Prevention Intervention Center, College of Public Health, University of Iowa College of Public Health, 105 River Street, S455 CPBH, Iowa City, IA 52242, USA
    J Clin Lipidol 7:292-303. 2013
    ..Treatment response to lipid-lowering therapy can vary in patients with the metabolic syndrome (MetS) due to various patient demographic and baseline characteristics...
  12. doi request reprint What is the role of advanced lipoprotein analysis in practice?
    Jennifer G Robinson
    Department of Epidemiology, University of Iowa, Iowa City, Iowa 52242, USA
    J Am Coll Cardiol 60:2607-15. 2012
    ..In contrast, a large body of evidence supports focusing on LDL cholesterol reduction and intensification of statin therapy to reduce cardiovascular risk...
  13. doi request reprint Achievement of specified low-density lipoprotein cholesterol, non-high-density lipoprotein cholesterol apolipoprotein B, and high-sensitivity C-reactive protein levels with ezetimibe/simvastatin or atorvastatin in metabolic syndrome patients with and with
    Jennifer G Robinson
    Departments of Epidemiology and Medicine, University of Iowa College of Public Health, Iowa City, IA 52242, USA
    J Clin Lipidol 5:474-82. 2011
    ..Metabolic syndrome (MetS) and atherosclerotic vascular disease (AVD) are associated with increased coronary heart disease risk...
  14. pmc Benefits associated with achieving optimal risk factor levels for the primary prevention of cardiovascular disease in older men
    Jennifer G Robinson
    Departments of Epidemiology and Medicine and Lipid Research Clinic, University of Iowa, 200 Hawkins Drive, SE 223 GH, Iowa City, IA 52242, USA
    J Clin Lipidol 6:58-65. 2012
    ..Most incident cardiovascular disease (CVD) occurs after patients reach the age of 65. The additive benefits of aggressive risk factor management with advancing age are not well established...
  15. doi request reprint Dalcetrapib: a review of Phase II data
    Jennifer G Robinson
    Lipid Research Clinic, University of Iowa, Iowa City, IA 52242, USA
    Expert Opin Investig Drugs 19:795-805. 2010
    ..Whether pharmacologically raising HDL-C per se with drug therapy will reduce cardiovascular events remains to be determined...
  16. doi request reprint Cardiovascular risk in women with non-specific chest pain (from the Women's Health Initiative Hormone Trials)
    Jennifer G Robinson
    Department of Epidemiology, University of Iowa, Iowa City, Iowa, USA
    Am J Cardiol 102:693-9. 2008
    ..In conclusion, a hospitalization for NSCP doubles the risk for a subsequent CAD event in postmenopausal women over the next 5 to 7 years and identifies them as candidates for aggressive risk factor treatment...
  17. ncbi request reprint Is a statin as part of a polypill the answer?
    Jennifer G Robinson
    Department of Epidemiology, Lipid Research Clinic, University of Iowa, Iowa City, IA 52242, USA
    Curr Atheroscler Rep 11:15-22. 2009
    ..Polypills in development hold great promise for reducing the global burden of cardiovascular disease...
  18. doi request reprint Meta-analysis of the relationship between non-high-density lipoprotein cholesterol reduction and coronary heart disease risk
    Jennifer G Robinson
    Lipid Research Clinic, University of Iowa, Iowa City, IA 52242, USA
    J Am Coll Cardiol 53:316-22. 2009
    ..To determine the relationship between non-high-density lipoprotein cholesterol (HDL-C) lowering and coronary heart disease (CHD) risk reduction for various lipid-modifying therapies...
  19. pmc Lack of association between 25(OH)D levels and incident type 2 diabetes in older women
    Jennifer G Robinson
    Department of Epidemiology, University of Iowa, Iowa City, Iowa, USA
    Diabetes Care 34:628-34. 2011
    ..To examine whether lower serum levels of serum 25-hydroxyvitamin (OH) D [25(OH)D] are associated with increased risk of developing type 2 diabetes...
  20. pmc Management of complex lipid abnormalities with a fixed dose combination of simvastatin and extended release niacin
    Jennifer G Robinson
    University of Iowa, Iowa City, IA, USA
    Vasc Health Risk Manag 5:31-43. 2009
    ..The safety profile of the combination appears to be similar to that of niacin and simvastatin used as monotherapies. Results of ongoing morbidity/mortality trials of ER niacin added to statin therapy are eagerly awaited...
  21. doi request reprint Lipid-altering efficacy and safety of ezetimibe/simvastatin versus atorvastatin in patients with hypercholesterolemia and the metabolic syndrome (from the VYMET study)
    Jennifer G Robinson
    University of Iowa College of Public Health, Iowa City, Iowa, USA
    Am J Cardiol 103:1694-702. 2009
    ..In conclusion, ezetimibe/simvastatin was more likely to result in lipid treatment end points than atorvastatin and was generally well tolerated at the doses compared in our patients...
  22. pmc Statin use and lipid levels in older adults: National Health and Nutrition Examination Survey, 2001 to 2006
    Jennifer G Robinson
    Department of Epidemiology and Medicine, University of Iowa, Iowa City, IA 52242, USA
    J Clin Lipidol 4:483-90. 2010
    ..Statins are the evidence-based drugs of choice for the prevention of cardiovascular disease (CVD)...
  23. doi request reprint Lipid-lowering therapy for the primary prevention of cardiovascular disease in the elderly: opportunities and challenges
    Jennifer G Robinson
    Lipid Research Clinic, Departments of Epidemiology and Medicine, University of Iowa, Iowa City, Iowa 52242, USA
    Drugs Aging 26:917-31. 2009
    ..With advancing age, the potential for benefit from cholesterol-lowering treatment needs to be weighed against the increasing risk of muscle and hepatic toxicity, as well as competing causes of morbidity and mortality...
  24. pmc Another treatment gap: restarting secondary prevention medications: the Women's Health Initiative
    Jennifer G Robinson
    Department of Medicine, University of Iowa, 200 Hawkins Drive SE 21C GH, Iowa City, IA 52242, USA
    J Clin Lipidol 4:36-45. 2010
    ..Women's long-term patterns of evidence-based preventive medication utilization following a coronary heart disease (CHD) diagnosis have not been sufficiently studied...
  25. pmc Atherosclerosis profile and incidence of cardiovascular events: a population-based survey
    Jennifer G Robinson
    Department of Medicine, University of Iowa, Iowa City, IA, USA
    BMC Cardiovasc Disord 9:46. 2009
    ..This study evaluated the characteristics of individuals with a diagnosis of atherosclerosis and estimated the incidence of CVD events to assist in the early identification of high-risk individuals...
  26. ncbi request reprint LDL reduction: how low should we go and is it safe?
    Jennifer G Robinson
    Lipid Research Clinic, 200 Hawkins Drive SE 226 GH, Iowa City, IA 52242, USA
    Curr Cardiol Rep 10:481-7. 2008
    ..To enhance patient outcomes, attention must be paid to characteristics that predict muscle and hepatic statin toxicity when considering using high-dose statin or combination statin therapy...
  27. pmc Omega-3 fatty acids and cognitive function in women
    Jennifer G Robinson
    Lipid Research Clinic, 200 Hawkins Drive, SE 226 GH, Iowa City, IA 52242, USA
    Womens Health (Lond Engl) 6:119-34. 2010
    ..Large, long-term trials in this area are needed...
  28. ncbi request reprint Antiatherosclerotic and antithrombotic effects of omega-3 fatty acids
    Jennifer G Robinson
    Department of Epidemiology, University of Iowa, Iowa City, Iowa 52242, USA
    Am J Cardiol 98:39i-49i. 2006
    ..Ongoing clinical trials may clarify the non-antiarrhythmic benefits of omega-3 fatty acid supplementation...
  29. ncbi request reprint Combination therapy with ezetimibe and simvastatin to achieve aggressive LDL reduction
    Jennifer G Robinson
    University of Iowa, Lipid Research Clinic, Departments of Epidemiology and Medicine, 200 Hawkins Drive, SE 226 GH, Iowa City, IA 52242, USA
    Expert Rev Cardiovasc Ther 4:461-76. 2006
    ..Ezetimibe 10 mg/simvastatin 80 mg lowers LDL by approximately 60% and has been demonstrated to be superior to the highest doses of atorvastatin and rosuvastatin for lowering LDL and raising high-density lipoprotein...
  30. ncbi request reprint Update on PPAR agonists: the clinical significance of FIELD and PROACTIVE
    Jennifer G Robinson
    Lipid Research Clinic, Department of Epidemiology and Medicine, University of Iowa, 200 Hawkins Drive SE, 226 GH, Iowa City, IA 52242, USA
    Curr Atheroscler Rep 9:64-71. 2007
    ..Further research is needed to determine the role of PPAR agonists in the prevention of cardiovascular disease...
  31. ncbi request reprint Elderly women diagnosed with nonspecific chest pain may be at increased cardiovascular risk
    Jennifer G Robinson
    Department of Epidemiology, University of Iowa, Iowa City, Iowa, USA
    J Womens Health (Larchmt) 15:1151-60. 2006
    ..Women are more likely than men to have nonspecific chest pain (NSCP) symptoms. The long-term outcomes in women discharged with a diagnosis of NSCP are unknown...
  32. ncbi request reprint Pleiotropic effects of statins: benefit beyond cholesterol reduction? A meta-regression analysis
    Jennifer G Robinson
    Department of Epidemiology, College of Public Health, University of Iowa, Iowa City, Iowa, USA
    J Am Coll Cardiol 46:1855-62. 2005
    ..This study sought to determine whether statins reduce coronary heart disease (CHD) risk more than other interventions that also primarily lower low-density lipoprotein cholesterol (LDL-C)...
  33. ncbi request reprint A "poly-portfolio" for secondary prevention: a strategy to reduce subsequent events by up to 97% over five years
    Jennifer G Robinson
    Department of Epidemiology, University of Iowa, Iowa City, Iowa, USA
    Am J Cardiol 95:373-8. 2005
    ..A secondary prevention polyportfolio holds great promise for reducing the burden of cardiovascular disease in the highest risk patients...
  34. ncbi request reprint Simvastatin: present and future perspectives
    Jennifer G Robinson
    Lipid Research Clinic, University of Iowa, Department of Epidemiology, Iowa City, IA 52242, USA
    Expert Opin Pharmacother 8:2159-27. 2007
    ..Coformulation of simvastatin with ezetimibe is now available, and coformulation with extended release niacin is under development...
  35. doi request reprint Models for describing relations among the various statin drugs, low-density lipoprotein cholesterol lowering, pleiotropic effects, and cardiovascular risk
    Jennifer G Robinson
    Department of Epidemiology, University of Iowa, Iowa City, IA, USA
    Am J Cardiol 101:1009-15. 2008
    ..The focus should remain on closing the treatment gap and improving adherence to therapies directed at lowering LDL cholesterol and non-high-density lipoprotein cholesterol to reduce the burden of cardiovascular disease...
  36. ncbi request reprint Is it time for a cardiovascular primary prevention trial in the elderly?
    Jennifer G Robinson
    Lipid Research Clinic, Department of Epidemiology, University of Iowa, Iowa City, IA 52242, USA
    Stroke 38:441-50. 2007
    ..However, few data are available for primary prevention of cardiovascular disease in those aged > or =70 years...
  37. ncbi request reprint How low to target LDL?
    Jennifer G Robinson
    Department of Epidemiology and Lipid Research Clinic, University of Iowa, IA 52242, USA
    Nat Clin Pract Endocrinol Metab 2:414-5. 2006
  38. doi request reprint Attitudes about health and health-related behaviors in patients with cardiovascular disease or at elevated risk for cardiovascular disease
    Jennifer G Robinson
    Department of Medicine, University of Iowa, Iowa City, IA, USA
    Prev Cardiol 12:136-43. 2009
    ..Frequent family doctor visits are an opportunity to improve the delivery of personalized health education and intervention programs...
  39. pmc Relationship of hypertension, blood pressure, and blood pressure control with white matter abnormalities in the Women's Health Initiative Memory Study (WHIMS)-MRI trial
    Lewis H Kuller
    Department of Epidemiology, University of Pittsburgh, Pittsburgh, PA 15213, USA
    J Clin Hypertens (Greenwich) 12:203-12. 2010
    ..The evidence to date supports tight control of BP levels, especially beginning at younger and middle age as a possible and perhaps only way to prevent dementia...
  40. pmc Lipoprotein particle concentrations may explain the absence of coronary protection in the women's health initiative hormone trials
    Judith Hsia
    Department of Medicine, George Washington University, Washington, DC, USA
    Arterioscler Thromb Vasc Biol 28:1666-71. 2008
    ..In an effort to explain this finding, we examined lipoprotein particle concentrations and their interactions with hormone therapy in a case-control substudy...
  41. doi request reprint Genetic Risk Score for Essential Hypertension and Risk of Preeclampsia
    Caitlin J Smith
    Department of Epidemiology, College of Public Health, University of Iowa, Iowa City, Iowa, USA
    Am J Hypertens 29:17-24. 2016
    ..Based on the hypertensive state that is characteristic of preeclampsia, we aimed to determine if established genetic risk scores (GRSs) for hypertension and blood pressure are associated with preeclampsia...
  42. pmc ω-3 fatty acids and domain-specific cognitive aging: secondary analyses of data from WHISCA
    Eric M Ammann
    From the Department of Epidemiology E M A, R W, R M C, J G R, College of Public Health, and Departments of Internal Medicine R W, J G R and Neurology N L D, College of Medicine, University of Iowa, Iowa City OmegaQuant Analytics J V P, W S H, Sioux Falls Department of Medicine W S H, Sanford School of Medicine, University of South Dakota, Vermillion and Department of Biostatistical Sciences M A E, Wake Forest School of Medicine, Winston Salem, NC
    Neurology 81:1484-91. 2013
    ..To test the hypothesis that higher levels of red blood cell (RBC) docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) have a protective association with domain-specific cognitive function in women aged 65 years and older...
  43. doi request reprint Effect of evolocumab or ezetimibe added to moderate- or high-intensity statin therapy on LDL-C lowering in patients with hypercholesterolemia: the LAPLACE-2 randomized clinical trial
    Jennifer G Robinson
    Department of Epidemiology, College of Public Health, University of Iowa, Iowa City2Department of Medicine, College of Public Health, University of Iowa, Iowa City
    JAMA 311:1870-82. 2014
    ..In phase 2 studies, evolocumab, a fully human monoclonal antibody to PCSK9, reduced LDL-C levels in patients receiving statin therapy...
  44. doi request reprint Lipid-lowering effects of ezetimibe and simvastatin in combination
    Nkechinyere Ijioma
    University of Iowa, Iowa City, IA, USA
    Expert Rev Cardiovasc Ther 9:131-45. 2011
    ..It also decreases C-reactive protein and exhibits some pleiotropic effects in a variety of patient populations. More data are needed to evaluate its effect on cardiovascular events/outcomes...
  45. pmc Omega-3 fatty acid biomarkers and subsequent depressive symptoms
    Jane E Persons
    Department of Epidemiology, College of Public Health, The University of Iowa, Iowa City, IA, USA
    Int J Geriatr Psychiatry 29:747-57. 2014
    ..We secondarily sought to characterize the association between dietary omega-3 fatty acid intake and depressive symptomatology...
  46. ncbi request reprint Evidence-based public health: an evolving concept
    Neal D Kohatsu
    Department of Epidemiology, College of Public Health, University of Iowa, Iowa City, Iowa 52242 1009, USA
    Am J Prev Med 27:417-21. 2004
    ..In this paper, we review the evolution of EBPH, propose a new definition for EBPH, and discuss developments that may support its further advancement...
  47. doi request reprint Longitudinal study of low serum LDL cholesterol and depressive symptom onset in postmenopause
    Jane E Persons
    The University of Iowa, Department of Epidemiology, 145 N Riverside Dr, Iowa City, IA 52246
    J Clin Psychiatry 77:212-20. 2016
    ..We secondarily assessed serum high-density lipoprotein (HDL-c), total cholesterol, and triglycerides...
  48. ncbi request reprint Comparison of effectiveness and safety of simvastatin in patients <75 versus > or =75 years of age with coronary, cerebral, or peripheral arterial disease
    Jennifer G Robinson
    Iowa Heart Center, Des Moines, Iowa City, Iowa 50314, USA
    Am J Cardiol 90:994-5. 2002
  49. pmc The cross-sectional relationship between body mass index, waist-hip ratio, and cognitive performance in postmenopausal women enrolled in the Women's Health Initiative
    Diana R Kerwin
    Division of Geriatrics, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA
    J Am Geriatr Soc 58:1427-32. 2010
    ..To determine whether body mass index (BMI) is independently associated with cognitive function in postmenopausal women and the relationship between body fat distribution as estimated by waist-hip ratio (WHR)...
  50. doi request reprint Insulin Resistance and Risk of Cardiovascular Disease in Postmenopausal Women: A Cohort Study From the Women's Health Initiative
    Michelle D Schmiegelow
    From the The Department of Health Research and Policy, Stanford University School of Medicine, Stanford, CA M D S, M A H Department of Cardiology, Gentofte University Hospital, Copenhagen, Denmark M D S The Department of Medicine, Stanford University School of Medicine, Stanford, CA H H, M L S, M A H Department of Epidemiology Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA R H M Department of Family and Preventive Medicine, University of California, San Diego M A Division of Cardiology, George Washington University School of Medicine and Health Sciences, Washington, DC L W M and Department of Epidemiology, College of Public Health, University of Iowa, Iowa City J G R
    Circ Cardiovasc Qual Outcomes 8:309-16. 2015
    ..Insulin resistance is associated with diabetes mellitus, but it is uncertain whether it improves cardiovascular disease (CVD) risk prediction beyond traditional cardiovascular risk factors...
  51. doi request reprint Genetic Predisposition to Dyslipidemia and Risk of Preeclampsia
    Cassandra N Spracklen
    Department of Epidemiology, University of Iowa College of Public Health, Iowa City, Iowa, USA Present address Department of Genetics, University of North Carolina Chapel Hill, Chapel Hill, North Carolina, USA
    Am J Hypertens 28:915-23. 2015
    ..We examined the association between the genetic predisposition to dyslipidemia and risk of preeclampsia using validated genetic markers of dyslipidemia...
  52. pmc Racial/Ethnic and gender gaps in the use of and adherence to evidence-based preventive therapies among elderly Medicare Part D beneficiaries after acute myocardial infarction
    Julie C Lauffenburger
    Division of Pharmaceutical Outcomes and Policy, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill J C L, C O, G F and Department of Epidemiology, College of Public Health, and Division of Cardiology, College of Medicine, University of Iowa, Iowa City J G R
    Circulation 129:754-63. 2014
    ....
  53. pmc Prevalent but moderate variation across small geographic regions in patient nonadherence to evidence-based preventive therapies in older adults after acute myocardial infarction
    Gang Fang
    Division of Pharmaceutical Outcomes and Policy, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC Department of Epidemiology, Division of Cardiology, College of Public Health, College of Medicine, University of Iowa, Iowa City, IA Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC
    Med Care 52:185-93. 2014
    ..It is unclear how prevalent patient adherence may be across small geographic areas and whether this geographic prevalence may vary...
  54. pmc Sleep duration, insomnia, and coronary heart disease among postmenopausal women in the Women's Health Initiative
    Megan Sands-Lincoln
    Department of Medicine, Center for Sleep and Circadian Neurobiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania 19104, USA
    J Womens Health (Larchmt) 22:477-86. 2013
    ..We sought to identify whether self-reported sleep duration and insomnia, based on a validated questionnaire, are associated with increased incident CHD and CVD among postmenopausal women...
  55. doi request reprint Association Between Preadmission Functional Status and Use and Effectiveness of Secondary Prevention Medications in Elderly Survivors of Acute Myocardial Infarction
    Elizabeth A Chrischilles
    Department of Epidemiology, College of Public Health, University of Iowa, Iowa City, Iowa
    J Am Geriatr Soc 64:526-35. 2016
    ..To determine whether function-related indicators (FRIs), derived from preadmission claims data, help explain the frequent practice of forgoing secondary prevention medications observed in Medicare...
  56. doi request reprint Embedding clinical interventions into observational studies
    Anne B Newman
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, A527 Crabtree Hall, 130 DeSoto Street, Pittsburgh, PA 15261, USA Electronic address
    Contemp Clin Trials 46:100-5. 2016
    ..Community engagement and stakeholder (including study participants) support are essential for these efforts to succeed. ..
  57. doi request reprint Nonstatin Low-Density Lipoprotein-Lowering Therapy and Cardiovascular Risk Reduction-Statement From ATVB Council
    Robert A Hegele
    From the Department of Medicine, Robarts Research Institute, Schulich School of Medicine, Western University, London, Ontario, Canada R A H Nemours Cardiac Center, A I duPont Hospital for Children, Wilmington, DE S S G Irving Institute for Clinical and Translational Research, Department of Medicine, Columbia University, New York, NY H N G Department of Medicine and Biochemistry, Atherogenomics Laboratory, University of Ottawa Heart Institute, Ottawa, Ontario, Canada R M Carbohydrate and Lipid Metabolism Research Unit, Faculty of Health Sciences, University of Witwatersrand, Johannesburg, South Africa F J R Department of Genetics D J R and Division of Translational Medicine and Human Genetics, Department of Medicine D J R, Perelman School of Medicine at the University of Pennsylvania, Philadelphia Department of Epidemiology and Medicine, University of Iowa, Iowa City J G R and Division of Cardiology, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA F K W
    Arterioscler Thromb Vasc Biol 35:2269-80. 2015
    ..As evidence for benefit in CVD prevention accumulates, we anticipate that clinical practice will shift toward more assertive LDL-lowering treatment, using both statins and nonstatins initiated earlier in appropriately selected patients. ..
  58. pmc Birth weight and subsequent risk of cancer
    Cassandra N Spracklen
    Department of Epidemiology, University of Iowa, 145 North Riverside Drive, S471 CPHB, Iowa City, IA 52242, United States
    Cancer Epidemiol 38:538-43. 2014
    ..We aimed to determine the association between self-reported birth weight and incident cancer in the Women's Health Initiative Observational Study cohort, a large multiethnic cohort of postmenopausal women...
  59. doi request reprint Calcium/vitamin D supplementation, serum 25-hydroxyvitamin D concentrations, and cholesterol profiles in the Women's Health Initiative calcium/vitamin D randomized trial
    Peter F Schnatz
    From the Departments of 1ObGyn and 2Internal Medicine, the Reading Hospital, Reading, PA Departments of 3ObGyn and 4Internal Medicine, Jefferson Medical College of Thomas Jefferson University, Philadelphia, PA 5Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 6Division of Endocrinology, Diabetes, and Metabolism, Department of Internal Medicine, The Ohio State University, Columbus, OH 7Center for Health Research NW, Kaiser Permanente, Portland, OR 8Departments of Epidemiology and Medicine, University of Iowa, Iowa City, IA 9Division of Preventive Medicine, School of Medicine, University of Alabama at Birmingham, Birmingham, AL 10Department of Preventive Medicine, University of Tennessee, Memphis, TN 11Division of Cardiology, Department of Internal Medicine, George Washington University School of Medicine and Health Sciences, Washington, DC 12Department of Epidemiology and Prevention, Wake Forest University, Winston Salem, NC 13Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital Harvard Medical School, Boston, MA and 14Sticht Center on Aging, Wake Forest University, Winston Salem, NC
    Menopause 21:823-33. 2014
    ..The objective of this study was to evaluate whether increased serum 25-hydroxyvitamin D3 (25OHD3) concentrations, in response to calcium/vitamin D (CaD) supplementation, are associated with improved lipids in postmenopausal women...
  60. doi request reprint A prospective study of the effect of hypertension and baseline blood pressure on cognitive decline and dementia in postmenopausal women: the Women's Health Initiative Memory Study
    Karen C Johnson
    Department of Preventive Medicine, University of Tennessee Health Science Center, Memphis, Tennesse 38163, USA
    J Am Geriatr Soc 56:1449-58. 2008
    ..To examine the relationship between baseline hypertension, blood pressure, and the development of cognitive decline in participants in the Women's Health Initiative Memory Study (WHIMS)...
  61. ncbi request reprint Atorvastatin in patients with type 2 diabetes mellitus undergoing dialysis
    Jennifer G Robinson
    N Engl J Med 353:1858-60; author reply 1858-60. 2005
  62. ncbi request reprint Identifying patients for aggressive cholesterol lowering: the risk curve concept
    Jennifer G Robinson
    Am J Cardiol 98:1405-8. 2006
    ....
  63. ncbi request reprint Statin pleiotropy: a popular concept but clinical significance unclear
    Jennifer G Robinson
    Cardiovasc Drugs Ther 21:81-3. 2007
  64. ncbi request reprint Safety of aggressive lipid management
    Michael H Davidson
    Radiant Research, Rush University Medical Center, Chicago, Illinois, USA
    J Am Coll Cardiol 49:1753-62. 2007
    ..In order to optimize patient outcomes, clinicians should be aware of specific patient characteristics, such as advancing age, gender, body mass index, or glomerular filtration rate, which predict muscle and hepatic statin toxicity...
  65. pmc Validity of diabetes self-reports in the Women's Health Initiative: comparison with medication inventories and fasting glucose measurements
    Karen L Margolis
    HealthPartners Research Foundation, Minneapolis, MN 55440 1524, USA
    Clin Trials 5:240-7. 2008
    ..Therefore, we studied whether self-report of prevalent and incident diabetes in Women's Health Initiative (WHI) participants was concordant with other diagnostic evidence of diabetes...
  66. ncbi request reprint Is it over for ezetimibe?
    Jennifer G Robinson
    Expert Rev Cardiovasc Ther 6:781-3. 2008
  67. pmc Enrollment in a brain magnetic resonance study: results from the Women's Health Initiative Memory Study Magnetic Resonance Imaging Study (WHIMS-MRI)
    Sarah A Jaramillo
    Division of Public Health Sciences, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, NC 27157, USA
    Acad Radiol 14:603-12. 2007
    ..We use data from a large MRI study to identify factors associated with differential enrollment and to examine potential biases this may produce in study results...
  68. doi request reprint Low-fat dietary pattern and risk of treated diabetes mellitus in postmenopausal women: the Women's Health Initiative randomized controlled dietary modification trial
    Lesley F Tinker
    Women s Health Initiative, Fred Hutchinson Cancer Research Center, PO Box 19024, Mail Stop M3 A410, Seattle, WA 98109, USA
    Arch Intern Med 168:1500-11. 2008
    ..This study was undertaken to assess the effects of a low-fat dietary pattern on incidence of treated diabetes among generally healthy postmenopausal women...
  69. ncbi request reprint Cholesterol management: targeting a lower low-density lipoprotein cholesterol concentration increases adult treatment panel-III goal attainment
    John R Crouse
    Wake Forest University School of Medicine, Winston Salem, North Carolina, USA
    Am J Cardiol 97:1667-9. 2006
  70. pmc Oophorectomy, hormone therapy, and subclinical coronary artery disease in women with hysterectomy: the Women's Health Initiative coronary artery calcium study
    Matthew A Allison
    University of California San Diego, La Jolla, CA, USA
    Menopause 15:639-47. 2008
    ..In this study, we aimed to determine the associations between coronary artery calcium (CAC) and hysterectomy, oophorectomy, and hormone therapy use with a focus on the duration of menopause for which there was no hormone therapy use...
  71. ncbi request reprint Lipid-lowering effects of statins: a comparative review
    Michael H Davidson
    Radiant Research, Chicago, IL, USA
    Expert Opin Pharmacother 7:1701-14. 2006
    ....