Research Topics
Species | K RobienSummaryAffiliation: University of Minnesota Country: USA Publications
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Detail Information
Publications
Vitamin D intake and breast cancer risk in postmenopausal women: the Iowa Women's Health StudyKim Robien
Division of Epidemiology and Community Health, University of Minnesota School of Public Health, 1300 S Second St, Suite 300, Minneapolis, MN 55454, USA
Cancer Causes Control 18:775-82. 2007..Studies evaluating all sources of vitamin D, especially sun exposure, are needed to fully understand the association between vitamin D and breast cancer risk...
Methylenetetrahydrofolate reductase and thymidylate synthase genotypes and risk of acute graft-versus-host disease following hematopoietic cell transplantation for chronic myelogenous leukemiaKim Robien
Cancer Prevention Program, Public Health Division, University of Washington Cancer Center, Seattle, Washington, USA
Biol Blood Marrow Transplant 12:973-80. 2006..A direct trade-off between drug toxicity and drug efficacy may play a role. Alternatively, the systemic folate environment, regulated by host tissues, might influence donor T-cell growth and activity...
Folic acid supplementation during methotrexate immunosuppression is not associated with early toxicity, risk of acute graft-versus-host disease or relapse following hematopoietic transplantationK Robien
Cancer Prevention Program, Fred Hutchinson Cancer Research Center, Seattle, WA, USA
Bone Marrow Transplant 37:687-92. 2006..Our results suggest that concurrent folic acid supplementation does not change MTX effectiveness or toxicity in this patient population...
Whole grain intake, incident hip fracture and presumed frailty in the Iowa Women's Health StudyDavid R Jacobs
Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, 1300 South 2nd Street, Suite 300, Minneapolis, MN 55454, USA
Br J Nutr 104:1537-43. 2010..Whole grain intake may increase the ability to respond to a questionnaire and self-report hip fracture, and could reflect less undocumented frailty...
Quality of life in a prospective cohort of elderly women with and without cancerDeAnn Lazovich
Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, Minnesota 55419, USA
Cancer 115:4283-97. 2009..Quality of life (QOL) is an important issue for cancer survivors; few studies are able to consider elderly populations, address long-term survival (>or=5 years), examine different cancers, or include a valid noncancer comparison group...
Poor adherence to dietary guidelines among adult survivors of childhood acute lymphoblastic leukemiaKim Robien
Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, 1300 S Second St, 300 WBOB, Minneapolis, MN 55454, USA
J Pediatr Hematol Oncol 30:815-22. 2008....
Green tea intake, MTHFR/TYMS genotype and breast cancer risk: the Singapore Chinese Health StudyMaki Inoue
Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA
Carcinogenesis 29:1967-72. 2008..Our findings suggest that folate pathway inhibition may be one mechanism through which green tea protects against breast cancer in humans...
Dietary flavonoid intake and risk of cancer in postmenopausal women: the Iowa Women's Health StudyGretchen J Cutler
Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, MN 55454, USA
Int J Cancer 123:664-71. 2008..93, 95% CI: 0.86-1.00). This study provides further support for a beneficial effect of flavonoid intake on lung cancer risk, especially among current and past smokers...
Nutrients, food groups, dietary patterns, and risk of pancreatic cancer in postmenopausal womenMaki Inoue-Choi
Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, 1300 S Second Street, Suite 300, Minneapolis, MN 55454, USA
Cancer Epidemiol Biomarkers Prev 20:711-4. 2011..Identifying modifiable risk factors for pancreatic cancer is important because of its poor prognosis. Previous findings on diet are inconsistent...
Predictors of oral mucositis in patients receiving hematopoietic cell transplants for chronic myelogenous leukemiaKim Robien
Cancer Prevention Research Program, Fred Hutchinson Cancer Research Center, Seattle, WA 98109-1024, USA
J Clin Oncol 22:1268-75. 2004..Future studies should investigate whether multivitamin supplementation before HCT could reduce mucositis severity...
Methylenetetrahydrofolate reductase genotype affects risk of relapse after hematopoietic cell transplantation for chronic myelogenous leukemiaKim Robien
Cancer Prevention Program, Public Health Sciences Division and Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109 1024, USA
Clin Cancer Res 10:7592-8. 2004..We evaluated the association of these polymorphisms with risk of relapse and bcr-abl mRNA transcript detection among 336 Caucasian patients who underwent allogeneic hematopoietic cell transplantation for chronic myelogenous leukemia...
Vitamin D status among long-term survivors of hematopoietic cell transplantationK Robien
Division of Epidemiology and Community Health, University of Minnesota School of Public Health, Minneapolis, MN 55454, USA
Bone Marrow Transplant 46:1472-9. 2011..Total vitamin D intake was the strongest single predictor of 25(OH)D concentrations. These findings suggest that 400-600 IU vitamin D per day appears to be required to achieve optimal serum 25(OH)D concentrations following HCT...
Folate during antifolate chemotherapy: what we know... and do not knowKim Robien
Cancer Prevention Program, Fred Hutchinson Cancer Research Center, PO Box 19024, M4 B402 Seattle, Washington 98109 1024, USA
Nutr Clin Pract 20:411-22. 2005..Future research in this area should include evaluation of pretreatment folate status and dietary and supplemental folate intake before, during, and after treatment...
Coffee and caffeine intake and the risk of ovarian cancer: the Iowa Women's Health StudyNatalie A Lueth
Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, MN, USA
Cancer Causes Control 19:1365-72. 2008..Our results suggest that a component of coffee other than caffeine, or in combination with caffeine, may be associated with increased risk of ovarian cancer in postmenopausal women who drink five or more cups of coffee a day...
Pharmacogenetics of folate-related drug targets in cancer treatmentKim Robien
Fred Hutchinson Cancer Research Center, Cancer Prevention Program, 1100 Fairview Ave N, M4-B402, Seattle, WA 98109 1024, USA
Pharmacogenomics 6:673-89. 2005..Findings to date illustrate a potential for targeting therapy based on patients' genotypes, in order to improve outcomes and reduce toxicity. However, larger, well-designed studies are needed to confirm these early findings...
Microsomal epoxide hydrolase polymorphisms are not associated with colon cancer riskKim Robien
Cancer Prevention Program, Fred Hutchinson Cancer Research Center, P.O. Box 19024, M4-B402, Seattle, WA 98109-1024, USA
Cancer Epidemiol Biomarkers Prev 14:1350-2. 2005
Alcohol intake and pancreatic cancer risk: a pooled analysis of fourteen cohort studiesJeanine M Genkinger
Department of Oncology, Lombardi Cancer Center, Georgetown University Medical Center, Washington, DC, USA
Cancer Epidemiol Biomarkers Prev 18:765-76. 2009..Few risk factors have been implicated in pancreatic cancer etiology. Alcohol has been theorized to promote carcinogenesis. However, epidemiologic studies have reported inconsistent results relating alcohol intake to pancreatic cancer risk...
Cancer pharmacogenetics: polymorphisms, pathways and beyondCornelia M Ulrich
Cancer Prevention Research Program, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
Nat Rev Cancer 3:912-20. 2003
5,10-Methylenetetrahydrofolate reductase polymorphisms and leukemia risk: a HuGE minireviewKim Robien
Cancer Prevention Research Program, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
Am J Epidemiol 157:571-82. 2003..Further investigation into the association between MTHFR polymorphisms and the risk of leukemia is warranted. It should include larger sample sizes and other polymorphisms in folate metabolism and address interactions with folate status...
Pharmacogenetics and folate metabolism -- a promising directionCornelia M Ulrich
Cancer Prevention Research Program, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave N, MP 900, Seattle, WA 98109 1024, USA
Pharmacogenomics 3:299-313. 2002..Findings to date illustrate the potential for targeting therapy based on patients' genotypes with improved outcomes and reduced toxicity...
