Kevin Robertson

Summary

Affiliation: University of North Carolina
Country: USA

Publications

  1. pmc Second assessment of NeuroAIDS in Africa
    Kevin Robertson
    Department of Neurology, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, North Carolina 27599 7025, USA
    J Neurovirol 14:87-101. 2008
  2. pmc Neuropsychological assessment of HIV-infected populations in international settings
    Kevin Robertson
    Department of Neurology, University of North Carolina School of Medicine, Chapel Hill, NC, USA
    Neuropsychol Rev 19:232-49. 2009
  3. pmc Improved neuropsychological and neurological functioning across three antiretroviral regimens in diverse resource-limited settings: AIDS Clinical Trials Group study a5199, the International Neurological Study
    K Robertson
    University of North Carolina, Chapel Hill, 27599 7025, USA
    Clin Infect Dis 55:868-76. 2012
  4. pmc Better quality of life with neuropsychological improvement on HAART
    Thomas D Parsons
    AIDS Neurological Center, University of North Carolina, Chapel Hill, NC 27599 7025, USA
    Health Qual Life Outcomes 4:11. 2006
  5. pmc Depression symptoms and cognitive function among individuals with advanced HIV infection initiating HAART in Uganda
    Noeline Nakasujja
    Department of Public Health Sciences, Karolinska Institute, Stockholm, Sweden
    BMC Psychiatry 10:44. 2010
  6. pmc Interpreting cerebrospinal fluid pleocytosis in HIV in the era of potent antiretroviral therapy
    Christina M Marra
    Harborview Medical Center, University of Washington, Seattle, WA, USA
    BMC Infect Dis 7:37. 2007
  7. pmc Pattern of neuropsychological performance among HIV positive patients in Uganda
    Kevin R Robertson
    Department of Neurology, University of North Carolina School of Medicine, Chapel Hill, NC, USA
    BMC Neurol 7:8. 2007
  8. pmc NeuroAIDS in Africa
    Kevin Robertson
    Department of Neurology, University of North Carolina, Chapel Hill, North Carolina 27599 7025, USA
    J Neurovirol 16:189-202. 2010
  9. ncbi request reprint The prevalence and incidence of neurocognitive impairment in the HAART era
    Kevin R Robertson
    Department of Neurology, UNC, Chapel Hill, North Carolina 27599, USA
    AIDS 21:1915-21. 2007
  10. doi request reprint HIV, antiretroviral therapies, and the brain
    Kevin J Liner
    Department of Neurology, University of North Carolina, 170 Manning Drive, Chapel Hill, NC 27599 7025, USA
    Curr HIV/AIDS Rep 7:85-91. 2010

Detail Information

Publications36

  1. pmc Second assessment of NeuroAIDS in Africa
    Kevin Robertson
    Department of Neurology, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, North Carolina 27599 7025, USA
    J Neurovirol 14:87-101. 2008
    ..The conference presentations summarized here highlight the need for further research on neuroAIDS in Africa and methods for assessing HIV-related neurological disorders...
  2. pmc Neuropsychological assessment of HIV-infected populations in international settings
    Kevin Robertson
    Department of Neurology, University of North Carolina School of Medicine, Chapel Hill, NC, USA
    Neuropsychol Rev 19:232-49. 2009
    ....
  3. pmc Improved neuropsychological and neurological functioning across three antiretroviral regimens in diverse resource-limited settings: AIDS Clinical Trials Group study a5199, the International Neurological Study
    K Robertson
    University of North Carolina, Chapel Hill, 27599 7025, USA
    Clin Infect Dis 55:868-76. 2012
    ..AIDS Clinical Trials Group (ACTG) A5199 compared the neurological and neuropsychological (NP) effects of 3 antiretroviral regimens in participants infected with human immunodeficiency virus type 1 (HIV-1) in resource-limited settings...
  4. pmc Better quality of life with neuropsychological improvement on HAART
    Thomas D Parsons
    AIDS Neurological Center, University of North Carolina, Chapel Hill, NC 27599 7025, USA
    Health Qual Life Outcomes 4:11. 2006
    ..Cognitive impairment can dramatically impact functional ability and day-to-day productivity. We assessed the relationship of quality of life (QOL) and neuropsychological functioning with successful HAART treatment...
  5. pmc Depression symptoms and cognitive function among individuals with advanced HIV infection initiating HAART in Uganda
    Noeline Nakasujja
    Department of Public Health Sciences, Karolinska Institute, Stockholm, Sweden
    BMC Psychiatry 10:44. 2010
    ..Initiation of highly active antiretroviral therapy (HAART) may have an effect on the prevalence and the change over time of depression symptoms and cognitive impairment among HIV-positive individuals...
  6. pmc Interpreting cerebrospinal fluid pleocytosis in HIV in the era of potent antiretroviral therapy
    Christina M Marra
    Harborview Medical Center, University of Washington, Seattle, WA, USA
    BMC Infect Dis 7:37. 2007
    ....
  7. pmc Pattern of neuropsychological performance among HIV positive patients in Uganda
    Kevin R Robertson
    Department of Neurology, University of North Carolina School of Medicine, Chapel Hill, NC, USA
    BMC Neurol 7:8. 2007
    ..The purpose of the current study was to evaluate the pattern of neuropsychological performance in a sample of HIV positive patients in comparison to HIV negative control subjects in Uganda...
  8. pmc NeuroAIDS in Africa
    Kevin Robertson
    Department of Neurology, University of North Carolina, Chapel Hill, North Carolina 27599 7025, USA
    J Neurovirol 16:189-202. 2010
    ....
  9. ncbi request reprint The prevalence and incidence of neurocognitive impairment in the HAART era
    Kevin R Robertson
    Department of Neurology, UNC, Chapel Hill, North Carolina 27599, USA
    AIDS 21:1915-21. 2007
    ..The effects of HAART on neurological disease are less well understood. The aim of this study was to assess the prevalence and incidence of neurocognitive impairment in individuals who initiated HAART as part of an AIDS clinical trial...
  10. doi request reprint HIV, antiretroviral therapies, and the brain
    Kevin J Liner
    Department of Neurology, University of North Carolina, 170 Manning Drive, Chapel Hill, NC 27599 7025, USA
    Curr HIV/AIDS Rep 7:85-91. 2010
    ....
  11. ncbi request reprint Effects of antiretroviral therapy on cognitive impairment
    Kevin J Liner
    School of Medicine, University of North Carolina at Chapel Hill, 3114 Bioinformatics Building CB7025, Neurology, Chapel Hill, NC 27599 7025, USA
    Curr HIV/AIDS Rep 5:64-71. 2008
    ..When to start antiretrovirals for the maximum cognitive benefit remains to be determined...
  12. ncbi request reprint Assessment of neuroAIDS in the international setting
    Kevin R Robertson
    Neurology, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 7025, USA
    J Neuroimmune Pharmacol 2:105-11. 2007
    ..There are a number of barriers in the assessment of neurological and neurocognitive effects in resource limited settings and some of these will be addressed...
  13. pmc Neurocognitive effects of treatment interruption in stable HIV-positive patients in an observational cohort
    K R Robertson
    Department of Neurology, University of North Carolina, 2128 Physician Office Building, Chapel Hill, NC 27599 7025, USA
    Neurology 74:1260-6. 2010
    ..Prior studies have shown improved neurocognition with initiation of antiretroviral treatment (ART) in HIV. We hypothesized that stopping ART would be associated with poorer neurocognitive function...
  14. pmc A multinational study of neurological performance in antiretroviral therapy-naïve HIV-1-infected persons in diverse resource-constrained settings
    Kevin Robertson
    University of North Carolina, Chapel Hill, NC 27599 7025, USA
    J Neurovirol 17:438-47. 2011
    ..Longitudinal follow-up after antiretroviral treatment initiation may help to define more broadly the role of HIV in these differences as well as the impact of treatment on performance...
  15. ncbi request reprint Timed Gait test: normative data for the assessment of the AIDS dementia complex
    Kevin R Robertson
    AIDS Neurological Center and Department of Neurology, School of Medicine, University of North Carolina at Chapel Hill, NC 27599 7025, USA
    J Clin Exp Neuropsychol 28:1053-64. 2006
    ..These normative data should prove useful in both recognition of ADC and treatment response. Given its minimal training requirements, the Timed Gait would have utility in resource limited settings...
  16. ncbi request reprint Thoughts of death and suicidal ideation in nonpsychiatric human immunodeficiency virus seropositive individuals
    Kevin Robertson
    AIDS Neurological Center, 3114 Bioinformatics, Departments of Neurology and Psychiatry, University North Carolina, School of Medicine, Chapel Hill, North Carolina 27599 7025, USA
    Death Stud 30:455-69. 2006
    ..Suicidal ideation did not increase with advancing disease. The high prevalence of suicidal ideation suggests inclusion of its assessment in HIV treatment regardless of stage...
  17. ncbi request reprint Assessment of neuroAIDS in Africa
    Kevin Robertson
    AIDS Neurological Center, 3114 Bioinformatics, Department of Neurology, University of North Carolina, School of Medicine, Chapel Hill, North Carolina 27599 7025, USA
    J Neurovirol 11:7-16. 2005
  18. ncbi request reprint The International HIV Dementia Scale: a new rapid screening test for HIV dementia
    Ned C Sacktor
    Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21224, USA
    AIDS 19:1367-74. 2005
    ..The objective of this study was to evaluate the sensitivity and specificity of a new screening test for HIV dementia, the International HIV Dementia Scale (IHDS) in cohorts from the US and Uganda...
  19. pmc Longitudinal neuropsychological test performance among HIV seropositive individuals in Uganda
    Ned Sacktor
    Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21224, USA
    J Neurovirol 19:48-56. 2013
    ..Possible reasons for this include practice effects among the no-ART group as well as improvements in their mood and overall quality of life...
  20. pmc Cross-sectional characterization of HIV-1 env compartmentalization in cerebrospinal fluid over the full disease course
    Patrick R Harrington
    Lineberger Comprehensive Cancer Center and UNC Center for AIDS Research, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, North Carolina 27599 7295, USA
    AIDS 23:907-15. 2009
    ....
  21. pmc Impact of combination antiretroviral therapy on cerebrospinal fluid HIV RNA and neurocognitive performance
    Christina M Marra
    Department of Neurology, University of Washington School of Medicine, Seattle, USA
    AIDS 23:1359-66. 2009
    ..To determine whether antiretroviral regimens with good central nervous system (CNS) penetration control HIV in cerebrospinal fluid (CSF) and improve cognition...
  22. ncbi request reprint HIV-associated cognitive impairment in sub-Saharan Africa--the potential effect of clade diversity
    Ned Sacktor
    Department of Neurology, Johns Hopkins University School of Medicine, Johns Hopkins Bayview Medical Center, Baltimore, MD 21224, USA
    Nat Clin Pract Neurol 3:436-43. 2007
    ..Further studies are needed to determine the true prevalence of HIV dementia in sub-Saharan Africa and to establish whether specific clade subtypes might influence the presentation of neurological complications...
  23. pmc Protein changes in CSF of HIV-infected patients: evidence for loss of neuroprotection
    Rick B Meeker
    Department of Neurology, University of North Carolina, CB 7025, 6113 Neuroscience Research Bldg, 115 Mason Farm Road, Chapel Hill, NC 27599, USA
    J Neurovirol 17:258-73. 2011
    ....
  24. ncbi request reprint Longitudinal characterization of depression and mood states beginning in primary HIV infection
    Jessica A Gold
    Department of Neurology, Yale University School of Medicine, 300 George Street, Room 8300C, New Haven, CT, USA
    AIDS Behav 18:1124-32. 2014
    ..Neither neuropsychological performance nor disease biomarkers correlated with depressed mood. Mood indices did not improve over time in the presence of ART. ..
  25. pmc Cerebrospinal fluid and neuroimaging biomarker abnormalities suggest early neurological injury in a subset of individuals during primary HIV infection
    Michael J Peluso
    Department of Neurology, Yale School of Medicine, New Haven, Connecticut, USA
    J Infect Dis 207:1703-12. 2013
    ..Cerebrospinal fluid (CSF) and neuroimaging abnormalities demonstrate neuronal injury during chronic AIDS, but data on these biomarkers during primary human immunodeficiency virus (HIV) infection is limited...
  26. ncbi request reprint HIV subtype is not associated with dementia among individuals with moderate and advanced immunosuppression in Kampala, Uganda
    Ned Sacktor
    Department of Neurology, Johns Hopkins Bayview Medical Center, 301 Building, Suite 2100, 4940 Eastern Ave, Baltimore, MD, 21224, USA
    Metab Brain Dis 29:261-8. 2014
    ..There was no association between HIV subtype and dementia among HIV+ individuals with moderate and advanced immunosuppression. Future studies should be performed to confirm these results...
  27. pmc Antiretroviral neurotoxicity
    Kevin Robertson
    Department of Neurology, University of North Carolina, Chapel Hill, NC 27599, USA
    J Neurovirol 18:388-99. 2012
    ..No additive effects were seen with combinations used clinically. These data provide initial evidence useful for the development of treatment strategies that might reduce the risk of antiretroviral neurotoxicity...
  28. pmc Increased human immunodeficiency virus type 1 (HIV-1) env compartmentalization in the presence of HIV-1-associated dementia
    Kimberly Ritola
    University of North Carolina at Chapel Hill, UNC Center for AIDS Research, Chapel Hill, NC 27599 7295, USA
    J Virol 79:10830-4. 2005
    ..Alternatively, HAD may be associated with a more pronounced state of immunosuppression that permits more extensive replication and independent evolution within the CNS compartment...
  29. ncbi request reprint Neurologic and neurodevelopmental manifestations of pediatric HIV/AIDS: a global perspective
    Annelies Van Rie
    Department of Epidemiology, School of Public Health, University of North Carolina at Chapel Hill, 2104F Mc Gavran Greenberg Hall, Chapel Hill, NC 27599 7435, USA
    Eur J Paediatr Neurol 11:1-9. 2007
    ..Neurotropic HIV-1 likely develops distinct genotypic characteristics in response to this unique environment. We reviewed the literature on pediatric neuroAIDS and identified gaps in the current knowledge...
  30. ncbi request reprint Editorial comment: déjà vu--neurologic complications of HIV infection in the expanding epidemic
    Richard W Price
    AIDS Read 15:144. 2005
  31. ncbi request reprint Clinical validation of the NeuroScreen
    Ronald J Ellis
    Department of Neurosciences, UCSD AntiViral Research Center and HIV Neurobehavioral Research Center, University of California, San Diego, California 92103, USA
    J Neurovirol 11:503-11. 2005
    ..However, because it yields substantial numbers of false positives and negatives, the NeuroScreen may be less useful in evaluating individual patients...
  32. ncbi request reprint Neurological complications of HIV infection and AIDS: current and future perspectives
    Paola Cinque
    Clinic of Infectious Diseases, San Raffaele Scientific Institute, Milano, Italy
    J Neurovirol 11:1-5. 2005
  33. ncbi request reprint Motor based assessment of neurocognitive functioning in resource-limited international settings
    Thomas D Parsons
    Center corrected for Creative Technologies, University of Southern California, Marina del Rey, CA 90292, USA
    J Clin Exp Neuropsychol 29:59-66. 2007
    ..Motor battery sensitivity to impairment diagnosis was 0.79 and specificity was 0.76. A motor battery may have broader utility to diagnose and monitor HIV related neurocognitive disorders in international settings...
  34. pmc HIV DNA and dementia in treatment-naïve HIV-1-infected individuals in Bangkok, Thailand
    Bruce Shiramizu
    Hawaii AIDS Clinical Research Program, University of Hawaii, Honolulu, HI, USA
    Int J Med Sci 4:13-8. 2007
    ..These results are consistent with a previous report among HAART-experienced subjects, thus further implicating HIV DNA in the pathogenesis of HAD...
  35. ncbi request reprint HIV suppression by HAART preserves cognitive function in advanced, immune-reconstituted AIDS patients
    J Allen McCutchan
    University of California San Diego, 150 West Washington Street, San Diego, CA 92103, USA
    AIDS 21:1109-17. 2007
    ..Epidemiological observations suggest that neuropsychological impairment might progress despite successful HAART therapy, but available prevalence estimates are based on populations that were selected for impairment...
  36. ncbi request reprint Assessment of human papillomavirus mRNA detection over time in cervical specimens collected in liquid based cytology medium
    Kate S Cuschieri
    Specialist Virology Centre, New Royal Infirmary of Edinburgh, 2nd Floor Microbiology, 51 Little France Crescent, Edinburgh EH16 4SA, UK
    J Virol Methods 124:211-5. 2005
    ..It is concluded that HPV RNA in routinely collected LBC specimens in PreservCyt can be detected for at least 14 days from sample collection...