DANIELLE ROBERTSON

Summary

Affiliation: University of Texas Southwestern Medical Center
Country: USA

Publications

  1. pmc The effects of silicone hydrogel lens wear on the corneal epithelium and risk for microbial keratitis
    Danielle M Robertson
    Department of Ophthalmology, The University of Texas Southwestern Medical Center, Dallas, TX 75390 9057, USA
    Eye Contact Lens 39:67-72. 2013
  2. pmc Hypoxia-induced downregulation of ΔNp63α in the corneal epithelium
    Danielle M Robertson
    Department of Ophthalmology, The University of Texas Southwestern Medical Center, Dallas, TX 75390 9057, USA
    Eye Contact Lens 38:214-21. 2012
  3. pmc Non-compliance with contact lens wear and care practices: a comparative analysis
    Danielle M Robertson
    The Department of Ophthalmology, UT Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, Texas 75390 9057, USA
    Optom Vis Sci 88:1402-8. 2011
  4. pmc Cellular distribution of the IGF-1R in corneal epithelial cells
    Danielle M Robertson
    Department of Ophthalmology, The University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390 9057, USA
    Exp Eye Res 94:179-86. 2012
  5. pmc A reconstituted telomerase-immortalized human corneal epithelium in vivo: a pilot study
    Danielle M Robertson
    Department of Ophthalmology, The University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390 9057, USA
    Curr Eye Res 36:706-12. 2011
  6. pmc Disruption of contact lens-associated Pseudomonas aeruginosa biofilms formed in the presence of neutrophils
    Danielle M Robertson
    Department of Ophthalmology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9057, USA
    Invest Ophthalmol Vis Sci 52:2844-50. 2011
  7. pmc C-terminal cleavage of DeltaNp63alpha is associated with TSA-induced apoptosis in immortalized corneal epithelial cells
    Danielle M Robertson
    Department of Ophthalmology, The University of Texas Southwestern Medical Center, Dallas, Texas 75390 9057, USA
    Invest Ophthalmol Vis Sci 51:3977-85. 2010
  8. pmc Characterization of DeltaNp63 isoforms in normal cornea and telomerase-immortalized human corneal epithelial cells
    Danielle M Robertson
    Department of Ophthalmology, The University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390 9057, USA
    Exp Eye Res 86:576-85. 2008
  9. doi request reprint The effect of nonpreserved care solutions on 12 months of daily and extended silicone hydrogel contact lens wear
    Danielle M Robertson
    Department of Ophthalmology, The University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA
    Invest Ophthalmol Vis Sci 49:7-15. 2008
  10. ncbi request reprint Bcl-2 and Bax regulation of corneal homeostasis in genetically altered mice
    Danielle M Robertson
    Department of Ophthalmology, The University of Texas Southwestern Medical Center, Dallas, TX 75390 9057, USA
    Eye Contact Lens 32:3-7. 2006

Research Grants

  1. The Role of BCL-2 in Corneal Epithelial Cell Shedding
    DANIELLE ROBERTSON; Fiscal Year: 2007
  2. P63/IGFBP3/BCL2 Control of Corneal Epithelial Homeostasis
    DANIELLE ROBERTSON; Fiscal Year: 2009
  3. P63/IGFBP3/BCL2 Control of Corneal Epithelial Homeostasis
    Danielle M Robertson; Fiscal Year: 2010

Detail Information

Publications20

  1. pmc The effects of silicone hydrogel lens wear on the corneal epithelium and risk for microbial keratitis
    Danielle M Robertson
    Department of Ophthalmology, The University of Texas Southwestern Medical Center, Dallas, TX 75390 9057, USA
    Eye Contact Lens 39:67-72. 2013
    ..In addition, new data supporting an interactive role for inflammation in facilitating PA adherence and internalization in the corneal epithelium will also be discussed...
  2. pmc Hypoxia-induced downregulation of ΔNp63α in the corneal epithelium
    Danielle M Robertson
    Department of Ophthalmology, The University of Texas Southwestern Medical Center, Dallas, TX 75390 9057, USA
    Eye Contact Lens 38:214-21. 2012
    ..The aim of this study was to establish a relationship between hypoxic stress and the expression of ΔNp63α in an established rabbit contact lens model and in cultured corneal epithelial cells...
  3. pmc Non-compliance with contact lens wear and care practices: a comparative analysis
    Danielle M Robertson
    The Department of Ophthalmology, UT Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, Texas 75390 9057, USA
    Optom Vis Sci 88:1402-8. 2011
    ..To compare the effects of existing patient awareness of lens-related complications and underlying risk factors on actual patient behavior during contact lens wear and care practices in two different clinical study populations...
  4. pmc Cellular distribution of the IGF-1R in corneal epithelial cells
    Danielle M Robertson
    Department of Ophthalmology, The University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390 9057, USA
    Exp Eye Res 94:179-86. 2012
    ..The identification of IGF-1R in the nucleus and complexed with E-cadherin suggests novel regulatory functions outside the canonical ligand-induced endocytosis signaling pathway...
  5. pmc A reconstituted telomerase-immortalized human corneal epithelium in vivo: a pilot study
    Danielle M Robertson
    Department of Ophthalmology, The University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390 9057, USA
    Curr Eye Res 36:706-12. 2011
    ..The purpose of this study was to assess the ability of a telomerase-immortalized human corneal epithelial cell line to generate a full thickness epithelium in vivo in athymic mice...
  6. pmc Disruption of contact lens-associated Pseudomonas aeruginosa biofilms formed in the presence of neutrophils
    Danielle M Robertson
    Department of Ophthalmology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9057, USA
    Invest Ophthalmol Vis Sci 52:2844-50. 2011
    ..Agents that target F-actin and DNA were tested as a therapeutic strategy for disrupting biofilms formed in the setting of neutrophils in vitro and for limiting the infectious bioburden in vivo...
  7. pmc C-terminal cleavage of DeltaNp63alpha is associated with TSA-induced apoptosis in immortalized corneal epithelial cells
    Danielle M Robertson
    Department of Ophthalmology, The University of Texas Southwestern Medical Center, Dallas, Texas 75390 9057, USA
    Invest Ophthalmol Vis Sci 51:3977-85. 2010
    ..In this study, the authors investigated a role for DeltaNp63 isoforms in caspase-mediated apoptosis in a telomerase-immortalized corneal epithelial cell line...
  8. pmc Characterization of DeltaNp63 isoforms in normal cornea and telomerase-immortalized human corneal epithelial cells
    Danielle M Robertson
    Department of Ophthalmology, The University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390 9057, USA
    Exp Eye Res 86:576-85. 2008
    ..Significantly, the localization of DeltaNp63 in central corneal epithelial cells with a loss of expression in superficial cells suggests that DeltaNp63 may play a role in mediating desquamative events at the ocular surface...
  9. doi request reprint The effect of nonpreserved care solutions on 12 months of daily and extended silicone hydrogel contact lens wear
    Danielle M Robertson
    Department of Ophthalmology, The University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA
    Invest Ophthalmol Vis Sci 49:7-15. 2008
    ..To determine the effects of nonpreserved care solutions on human corneal epithelium in long-term daily wear (DW) compared with overnight (extended) wear (EW) of hyper-oxygen-permeable silicone hydrogel contact lenses...
  10. ncbi request reprint Bcl-2 and Bax regulation of corneal homeostasis in genetically altered mice
    Danielle M Robertson
    Department of Ophthalmology, The University of Texas Southwestern Medical Center, Dallas, TX 75390 9057, USA
    Eye Contact Lens 32:3-7. 2006
    ....
  11. pmc Insulin-like Growth Factor Binding Protein-3 expression in the human corneal epithelium
    Danielle M Robertson
    Department of Ophthalmology, The University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390 9057, USA
    Exp Eye Res 85:492-501. 2007
    ..The differential localization and effect(s) on apoptosis suggest that the effects of IGFBP3 are likely tissue compartment and receptor specific and may be regulated by glycosylation...
  12. ncbi request reprint Pseudomonas aeruginosa corneal binding after 24-hour orthokeratology lens wear
    Patrick M Ladage
    Department of Ophthalmology, University of Texas, Southwestern Medical Center at Dallas, Dallas, TX 75390 9057, USA
    Eye Contact Lens 30:173-8. 2004
    ..To examine the effect of short-term 24-hr orthokeratology lens (OKL) wear on Pseudomonas aeruginosa binding, epithelial surface cell morphology, epithelial sheet thickness, and stromal thickness in a rabbit model...
  13. ncbi request reprint The role of contact lens type, oxygen transmission, and care-related solutions in mediating epithelial homeostasis and pseudomonas binding to corneal cells: an overview
    Danielle M Robertson
    Department of Ophthalmology, The University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390 9057, USA
    Eye Contact Lens 33:394-8; discussion 399-400. 2007
    ..Significantly, hyper-oxygen-transmissible lenses in any wearing mode with non-preserved care solutions appear to offer the safest potential clinical choice for contact lens wear...
  14. ncbi request reprint Current concepts: contact lens related Pseudomonas keratitis
    Danielle M Robertson
    Department of Ophthalmology, University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Boulevard, Dallas, TX 75390 9057, USA
    Cont Lens Anterior Eye 30:94-107. 2007
    ..Non-toxic blockade of raft formation in vitro or in vivo effectively abrogates PA internalization and may represent a unique, new strategy to prevent or ameliorate lens-related PA microbial keratitis...
  15. pmc Castroviejo Lecture 2009: 40 years in search of the perfect contact lens
    H Dwight Cavanagh
    Department of Ophthalmology, University of Texas Southwestern Medical Center, Dallas, TX 75390 9057, USA
    Cornea 29:1075-85. 2010
    ....
  16. ncbi request reprint Characterization of growth and differentiation in a telomerase-immortalized human corneal epithelial cell line
    Danielle M Robertson
    Department of Ophthalmology, The University of Texas Southwestern Medical Center, Dallas, Texas, USA
    Invest Ophthalmol Vis Sci 46:470-8. 2005
    ..To develop and characterize a telomerase-immortalized human corneal epithelial cell line (hTCEpi) to serve as an in vitro model for studying the molecular mechanisms involved in regulating human corneal epithelial cell differentiation...
  17. ncbi request reprint Can postlens tear thickness be measured using three-dimensional in vivo confocal microscopy?
    W Matthew Petroll
    Department of Ophthalmology, University of Texas Southwestern Medical Center, Dallas, TX 75390 9057, USA
    Eye Contact Lens 29:S110-4; discussion S115-8, S192-4. 2003
    ..This study investigated the feasibility of using in vivo CMTF to measure postlens tear thickness (PLTT)...
  18. ncbi request reprint Pseudomonas aeruginosa keratitis in an atopic silicone hydrogel lens wearer with rosacea
    Danielle M Robertson
    Department of Ophthalmology, The University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390 9057, USA
    Eye Contact Lens 31:254-6. 2005
    ....
  19. ncbi request reprint Severe acanthamoeba keratitis after overnight orthokeratology
    Danielle M Robertson
    Department of Ophthalmology, The University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390 9057, USA
    Eye Contact Lens 33:121-3. 2007
    ..To document a clinical case of Acanthamoeba keratitis associated with orthokeratology overnight lens wear that resulted in severe, permanent vision loss...

Research Grants5

  1. The Role of BCL-2 in Corneal Epithelial Cell Shedding
    DANIELLE ROBERTSON; Fiscal Year: 2007
    ..4) That events leading to increased apoptosis such as UV light signal surface cell apoptosis through the phosphorylation of BCL-2. ..
  2. P63/IGFBP3/BCL2 Control of Corneal Epithelial Homeostasis
    DANIELLE ROBERTSON; Fiscal Year: 2009
    ....
  3. P63/IGFBP3/BCL2 Control of Corneal Epithelial Homeostasis
    Danielle M Robertson; Fiscal Year: 2010
    ....