Research Topics
| Mark S RobertsSummaryAffiliation: University of Pittsburgh Country: USA Publications
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Publications
Survival after liver transplantation in the United States: a disease-specific analysis of the UNOS databaseMark S Roberts
Section of Decision Sciences and Clinical Systems Modeling, Division of General Medicine, University of Pittsburgh School of Medicine, Center for Research on Health Care, Pittsburgh, PA 15213, USA
Liver Transpl 10:886-97. 2004..However, a significant portion of the difference in survival between diseases arises from differences in clinical characteristics at the time of transplantation...
Short-term mortality in acute pulmonary embolism: clot burden and signs of right heart dysfunction at CT pulmonary angiographyAlessandro Furlan
Department of Radiology, University of Pittsburgh Medical Center, 200 Lothrop St, Pittsburgh, PA 15213, USA
Radiology 265:283-93. 2012....
Cost-effectiveness of pneumococcal polysaccharide vaccine among healthcare workers during an influenza pandemicKenneth J Smith
Section of Decision Sciences and Clinical Systems Modeling, University of Pittsburgh, Pittsburgh, PA 15213, USA
Am J Manag Care 16:200-6. 2010..To assess the usefulness and cost-effectiveness of pneumococcal polysaccharide vaccine (PPV) among healthcare workers compared with nonuse of PPV during an influenza pandemic...
Age, revaccination, and tolerance effects on pneumococcal vaccination strategies in the elderly: a cost-effectiveness analysisKenneth J Smith
University of Pittsburgh, Pittsburgh, PA, USA
Vaccine 27:3159-64. 2009..Revaccination strategies for the elderly are less cost-effective, particularly when prior vaccination and vaccine tolerance are considered...
Economic evaluation of standing order programs for pneumococcal vaccination of hospitalized elderly patientsDonald B Middleton
Department of Family Medicine, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA 15232, USA
Infect Control Hosp Epidemiol 29:385-94. 2008..The purpose of this study was to estimate the cost-effectiveness of SOPs for pneumococcal polysaccharide vaccine (PPV) vaccination for patients 65 years of age or older in 2 types of hospital...
Development and validation of hospital "end-of-life" treatment intensity measuresAmber E Barnato
Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
Med Care 47:1098-105. 2009..Health care utilization among decedents is increasingly used as a measure of health care efficiency, but decedent-based measures may be biased estimates of care received by "dying" patients...
Cost-effectiveness of implementing the chronic care model for diabetes care in a military populationShihchen Kuo
Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
J Diabetes Sci Technol 5:501-13. 2011..The CCM was implemented at U.S. Air Force Wilford Hall Medical Center through the Diabetes Outreach Clinic (DOC) in 2006, but its cost-effectiveness in this setting is unknown...
Use of dynamic microsimulation to predict disease progression in patients with pneumonia-related sepsisGorkem Saka
Department of Industrial Engineering, University of Pittsburgh, 3700 Ohara St, 3700 Benedum Hall, Pittsburgh, PA 15261, USA
Crit Care 11:R65. 2007....
Is survival better at hospitals with higher "end-of-life" treatment intensity?Amber E Barnato
Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA
Med Care 48:125-32. 2010..Concern regarding wide variations in spending and intensive care unit use for patients at the end of life hinges on the assumption that such treatment offers little or no survival benefit...
Cost-effectiveness of alternative outpatient pelvic inflammatory disease treatment strategiesKenneth J Smith
Section of Decision Sciences and Clinical Systems Modeling, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
Sex Transm Dis 34:960-6. 2007..Effectiveness differences between outpatient pelvic inflammatory disease (PID) treatment regimens are uncertain, but significant differences in cost exist...
Cost-effectiveness of different screening strategies for osteoporosis in postmenopausal womenSmita Nayak
University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
Ann Intern Med 155:751-61. 2011..The best strategies to screen postmenopausal women for osteoporosis are not clear...
Quality of life utilities for pelvic inflammatory disease health statesKenneth J Smith
Section of Decision Sciences and Clinical Systems Modeling, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
Sex Transm Dis 35:307-11. 2008..Utilities for PID could have important implications on the cost-effectiveness of interventions to prevent and manage this disease...
Alternative strategies for adult pneumococcal polysaccharide vaccination: a cost-effectiveness analysisKenneth J Smith
Section of Decision Sciences and Clinical Systems Modeling, School of Medicine, University of Pittsburgh, Pittsburgh, PA, United States
Vaccine 26:1420-31. 2008..PPV at ages 50/65 may be clinically and, depending on cost-effectiveness criterion used, economically favored over present vaccination recommendations...
Cost-effectiveness analysis of efforts to reduce risk of type 2 diabetes and cardiovascular disease in southwestern Pennsylvania, 2005-2007Kenneth J Smith
University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
Prev Chronic Dis 7:A109. 2010..We assessed the cost-effectiveness of a community-based, modified Diabetes Prevention Program (DPP) designed to reduce risk factors for type 2 diabetes and cardiovascular disease...
Factors associated with osteoporosis screening and recommendations for osteoporosis screening in older adultsSmita Nayak
School of Medicine, Department of Medicine, Division of General Internal Medicine, Section of Decision Sciences and Clinical Systems Modeling, University of Pittsburgh, Pittsburgh, PA 15213, USA
J Gen Intern Med 24:585-91. 2009..Osteoporosis screening rates are low, and it is unclear which patient factors are associated with screening and physician recommendations for screening...
Time from sexually transmitted infection acquisition to pelvic inflammatory disease development: influence on the cost-effectiveness of different screening intervalsKenneth J Smith
School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA
Value Health 10:358-66. 2007..Nevertheless, the time from STI acquisition to PID development, possibly an important factor to consider in screening interval choice, is unknown and its influence on the effectiveness and cost-effectiveness of screening is unclear...
Impact of generic alendronate cost on the cost-effectiveness of osteoporosis screening and treatmentSmita Nayak
Section of Decision Sciences and Clinical Systems Modeling, Division of General Internal Medicine, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America
PLoS ONE 7:e32879. 2012..The objective of this study was to investigate the impact of alendronate cost on the cost-effectiveness of osteoporosis screening and treatment in postmenopausal women...
Using mechanistic models to simulate comparative effectiveness trials of therapy and to estimate long-term outcomes in HIV careMark S Roberts
Department of Health Policy and Management, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
Med Care 48:S90-5. 2010..Mechanistic models of HIV infection can be used to conduct virtual therapeutic trials with the goal of predicting outcomes, some of which are long-term and may not fall within the time frame of a typical therapeutic trial...
Inflammatory markers at hospital discharge predict subsequent mortality after pneumonia and sepsisSachin Yende
The Clinical Research, Investigation, and Systems Modeling of Acute Illness CRISMA Laboratory, Department of Critical Care Medicine, Graduate School of Pubic Health, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
Am J Respir Crit Care Med 177:1242-7. 2008..Survivors of hospitalization for community-acquired pneumonia (CAP) are at increased risk of cardiovascular events, repeat infections, and death in the following months but the cause is unknown...
Osteoporosis screening preferences of older adultsSmita Nayak
Department of Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA
J Clin Densitom 12:279-86. 2009..Many older individuals would prefer the "best" test for osteoporosis screening, and may be willing to travel or pay more to obtain a better test...
Cardiovascular disease risk prediction in type 1 diabetes: accounting for the differencesKristine Ruppert
Department of Epidemiology, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA, United States
Diabetes Res Clin Pract 78:234-7. 2007..005), non-HDLc (p=0.0005), WHR (p=0.003), and estimated glucose disposal rate (p=0.002) were associated. Risk factors not considered by the Framingham risk equation may account for the lack of fit and should be examined further...
Expectations of groups versus pairs of attendings and residents about phone communications and bedside evaluation of hospitalized patientsGary Tabas
Division of General Internal Medicine, Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15232, USA
Teach Learn Med 17:217-27. 2005..Residents covering attendings' patients must decide when to call the attending and when to evaluate patients at the bedside for new clinical events. Conflicts arise when residents and attendings disagree about these decisions...
Health utility ratings for a spectrum of alcohol-related health statesKevin L Kraemer
Center for Research on Health Care, Division of General Internal Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
Med Care 43:541-50. 2005..Preference-based utility ratings for health conditions are important components of cost-utility analyses and population burden of disease estimates. However, utility ratings for alcohol problems have not been determined...
The effect of pulmonary artery catheter use on costs and long-term outcomes of acute lung injuryGilles Clermont
Clinical Research, Investigation, and Systems Modeling of Acute Illness Center, Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
PLoS ONE 6:e22512. 2011..central venous catheter (CVC). We explored if use of the PAC in ALI is justified by a beneficial cost-effectiveness profile...
Economics of nerve block pain management after anterior cruciate ligament reconstruction: potential hospital cost savings via associated postanesthesia care unit bypass and same-day dischargeBrian A Williams
Same Day Surgical Services, University of Pittsburgh Medical Center, Pennsylvania 15203, USA
Anesthesiology 100:697-706. 2004..In this study, the authors examine the associations of nerve block analgesia for these patients and its associated reductions in PACU use, hospital admission, and hospital costs...
Cost-effectiveness of newer treatment strategies for influenzaKenneth J Smith
Section of Decision Sciences and Clinical Systems Modeling, Division of General Internal Medicine, and the Center for Research on Health Care, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
Am J Med 113:300-7. 2002..Recent advances in the diagnosis and treatment of influenza, such as rapid testing and neuraminidase inhibitor therapy, are available, but their place in clinical practice and their cost-effectiveness have not been determined...
Procuring organ donors as a health investment: how much should we be willing to spend?John Mendeloff
Graduate School of Public Health, Department of Health Policy and Management, University of Pittsburgh, Pittsburgh, PA 15260, USA
Transplantation 78:1704-10. 2004..Our objective was not only to see whether organ procurement is a "good" health investment, but also to clarify how much it is worth spending to obtain additional donors...
Long-term HIV/AIDS survival estimation in the highly active antiretroviral therapy eraJoseph T King
Section of Neurosurgery, Surgical Service Line, VA Pittsburgh Healthcare System, Pittsburgh, Pennsylvania, USA
Med Decis Making 23:9-20. 2003....
Differences in access to liver transplantation: disease severity, waiting time, and transplantation center volumeJawad Ahmad
Veterans Affairs Pittsburgh Healthcare System and University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
Ann Intern Med 146:707-13. 2007..Allocation based on MELD scores should ensure that sicker patients receive transplants first regardless of transplantation center volume...
Causal system modeling in chronic disease epidemiology: a proposalRoberta B Ness
Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA
Ann Epidemiol 17:564-8. 2007..In all of these ways, they have the capability to advance the science of epidemiology...
Hospitalization for pelvic inflammatory disease: a cost-effectiveness analysisKenneth J Smith
Section of Decision Sciences and Clinical Systems Modeling, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
Sex Transm Dis 34:108-12. 2007..Nulliparous women are frequently hospitalized for treatment of pelvic inflammatory disease (PID)...
Sequential medication strategies for postherpetic neuralgia: a cost-effectiveness analysisKenneth J Smith
Section of Decision Sciences and Clinical Systems Modeling, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
J Pain 8:396-404. 2007..This decision analysis-based synthesis of effectiveness and cost data found that recommended treatment algorithms are also economically reasonable...
The Effect of Race, Sex, and Insurance Status on Time-to-Listing Decisions for Liver TransplantationCindy L Bryce
Division of General Internal Medicine, Department of Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA
J Transplant 2010:467976. 2010..The early time period from diagnosis to listing for liver transplantation reveals unwanted variation related to demographics that jeopardizes overall fairness of organ allocation and needs to be further explored...
Virtual epidemic in a virtual city: simulating the spread of influenza in a US metropolitan areaBruce Y Lee
Section of Decision Sciences and Clinical Systems Modeling, University of Pittsburgh, Pittsburgh, PA 15213, USA
Transl Res 151:275-87. 2008..Our simulation may serve as a virtual laboratory to better understand the way different factors and interventions affect the spread of influenza...
Simulation and critical care modelingJennifer E Kreke
Department of Industrial Engineering, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
Curr Opin Crit Care 10:395-8. 2004..SUMMARY: Simulation models provide useful tools for organizing and analyzing the interactions between therapies, tradeoffs, and outcomes...
Cost-effectiveness of inhaled nitric oxide in the treatment of neonatal respiratory failure in the United StatesDerek C Angus
Clinical Research, Investigation, and Systems Modeling of Acute Illness CRISMA Laboratory, Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
Pediatrics 112:1351-60. 2003..Our objective was to estimate the cost-effectiveness ratio of iNO in this population...
Accuracy and reproducibility of blood clot burden quantification with pulmonary CT angiographyAlessandro Furlan
Department of Radiology, University of Pittsburgh Medical Center, PA 15213, USA
AJR Am J Roentgenol 196:516-23. 2011..The purpose of our study was to assess the accuracy and reproducibility of clot burden quantification with pulmonary CT angiography (CTA)...
Teaching medical decision modeling: a qualitative description of student errors and curriculum responsesKenneth J Smith
Section of Decision Sciences and Clinical Systems Modeling, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
Med Decis Making 26:583-8. 2006..Originally, the only assignment was an abstract and 10-minute presentation describing their solution, but now periodic homework monitors progress...
Preference-based quality of life measurement in patients with cervical spondylotic myelopathyJoseph T King
Section of Neurosurgery, Surgical Service Line, Veterans Affairs Pittsburgh Healthcare System, Pittsburgh, PA, USA
Spine (Phila Pa 1976) 29:1271-80. 2004..Prospective cross-sectional observational cohort study...
Quality of life assessment with the medical outcomes study short form-36 among patients with cervical spondylotic myelopathyJoseph T King
Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
Neurosurgery 52:113-20; discussion 121. 2003..We used Medical Outcomes Study Short Form-36 (SF-36), a generic quality of life outcome-assessment instrument, to assess the quality of life among patients with CSM...
Influence of alternative thresholds for initiating HIV treatment on quality-adjusted life expectancy: a decision modelR Scott Braithwaite
Yale University and Veterans Affairs Connecticut Healthcare System, West Haven, Connecticut 06516, USA
Ann Intern Med 148:178-85. 2008..The optimal threshold for initiating HIV treatment is unclear...
Potential value of regionalized intensive care for mechanically ventilated medical patientsJeremy M Kahn
Division of Pulmonary, Allergy, and Critical Care, University of Pennsylvania School of Medicine, 723 Blockley Hall, 423 Guardian Drive, Philadelphia, PA 19104, USA
Am J Respir Crit Care Med 177:285-91. 2008..Regionalization has been proposed as a method to improve outcomes for medical patients receiving mechanical ventilation in the intensive care unit...
What does the value of modern medicine say about the $50,000 per quality-adjusted life-year decision rule?R Scott Braithwaite
Department of Medicine, Section of General Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA
Med Care 46:349-56. 2008..However, many investigators have questioned the scientific basis of this rule, and it has not been updated...
Depressive symptoms and subsequent alcohol use and problems: a prospective study of medical inpatients with unhealthy alcohol useTibor P Palfai
Department of Psychology, College of Arts and Sciences, Boston University, 648 Beacon Street, Boston, Massachusetts 02215, USA
J Stud Alcohol Drugs 68:673-80. 2007..We sought to determine whether depressive symptoms assessed during hospitalization predicted alcohol use and alcohol-related problems during the subsequent year among medically ill patients...
A clinically based discrete-event simulation of end-stage liver disease and the organ allocation processSteven M Shechter
Department of Industrial Engineering, University of Pittsburgh, Pennsylvania, USA
Med Decis Making 25:199-209. 2005..CONCLUSION: The authors created a discrete-event simulation model that represents the biology of end-stage liver disease and the health care organization of transplantation in the United States...
Estimating the proportion of patients infected with HIV who will die of comorbid diseasesR Scott Braithwaite
VAMC New Haven and Yale University School of Medicine, New Haven, Conn, USA
Am J Med 118:890-8. 2005..Effective antiretroviral therapies have improved the prognosis for patients infected with the human immunodeficiency virus (HIV). We aimed to estimate the likelihood that HIV-infected patients would die of comorbid disease...
Cervical spondylotic myelopathy, depression, and anxiety: a cohort analysis of 89 patientsMichael R Stoffman
Department of Neurosurgery, Yale University, New Haven, Connecticut, USA
Neurosurgery 57:307-13; discussion 307-13. 2005....
Oral anticoagulation strategies after a first idiopathic venous thromboembolic eventDrahomir Aujesky
Division of General Internal Medicine, Department of Medicine, University of Pittsburgh, Pennsylvania, USA
Am J Med 118:625-35. 2005..We used decision analysis to evaluate clinical and economic outcomes of different anticoagulation strategies with warfarin...
Incorporating quality of evidence into decision analytic modelingR Scott Braithwaite
Yale University School of Medicine and Connecticut Veterans Affairs Healthcare System, New Haven, Connecticut 06516, USA
Ann Intern Med 146:133-41. 2007..We conclude that the results of decision modeling may vary dramatically depending on the stringency of the criteria for selecting evidence to use in the model...
The short form-12 and the measurement of health status in patients with cerebral aneurysms: performance, validity, and reliabilityJoseph T King
Section of Neurosurgery, Veterans Administration Connecticut Healthcare System, West Haven, Connecticut 06516, USA
J Neurosurg 102:489-94. 2005..The authors assessed the performance, validity, and reliability of the Short Form-12 (SF-12), a self-administered written survey instrument, to assess health status in patients with cerebral aneurysms...
Deficiencies of cardiovascular risk prediction models for type 1 diabetesJanice C Zgibor
Department of Epidemiology, University of Pittsburgh Graduate School of Public Health, USA
Diabetes Care 29:1860-5. 2006..Future research should focus on determining the risk factors accounting for the lack of fit and developing prediction models specific to this high-risk group...
Cognitive functioning in patients with cerebral aneurysms measured with the mini mental state examination and the telephone interview for cognitive statusJoseph T King
Section of Neurosurgery, Veterans Affairs Connecticut Healthcare System, West Haven, Connecticut 06516, USA
Neurosurgery 59:803-10; discussion 810-1. 2006..MMSE and TICS scores are often dichotomized to classify patients as cognitively impaired or not. Frequently, after an initial MMSE face-to-face evaluation, the TICS is used for follow-up assessments by telephone...
Multimodal assessment after surgery for cervical spondylotic myelopathyJoseph T King
Section of Neurosurgery, Veterans Administration Connecticut Healthcare System, West Haven Connecticut 06516, USA
J Neurosurg Spine 2:526-34. 2005..In the present study the authors used three types of outcomes instruments to assess the results of CSM surgery...
Preference-based quality of life in patients with cerebral aneurysmsJoseph T King
Section of Neurosurgery, VA Connecticut Healthcare System 112 950 Campbell Ave, West Haven, CT 06516, USA
Stroke 36:303-9. 2005..An additional advantage of preference-based QOL values is that they can be incorporated into decision analyses and cost-effectiveness analyses...
Positive association between current health and health values for hypothetical disease statesJoseph T King
Section of Neurosurgery, Acute Care Service Line, Surgical Service 112, VA Connecticut Healthcare System, 950 Campbell Avenue, West Haven 06516, USA
Med Decis Making 24:367-78. 2004..Valuations of hypothetical health state scenarios can be affected by participant characteristics...
Health status versus utilities of patients with end-stage liver diseaseCindy L Bryce
Division of General Internal Medicine, Department of Medicine, University of Cincinnati, Cincinnati, OH, USA
Qual Life Res 13:773-82. 2004..For formal economic evaluations such as cost effectiveness analyses, only direct measures of utility can be used to quantify health states...
"Perfect health" versus "disease free": the impact of anchor point choice on the measurement of preferences and the calculation of disease-specific disutilitiesJoseph T King
Section of Neurosurgery, Surgical Service Line, Center for Health Equity Research and Promotion, VA Pittsburgh Healthcare System, USA
Med Decis Making 23:212-25. 2003....
Optimizing management and financial performance of the teaching ambulatory care clinicJames E Stahl
Received from the Departments of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Mass 02114, USA
J Gen Intern Med 18:266-74. 2003..To examine how to optimize teaching ambulatory care clinics performance with regard to access to care, access to teaching, and financial viability...
Impact of timing of initiation of dialysis on mortalitySrinivasan Beddhu
Renal Section, Salt Lake VA Healthcare System, Division of Nephrology and Hypertension, and Division of Clinical Epidemiology, University of Utah School of Medicine, Salt Lake City, Utah 84112, USA
J Am Soc Nephrol 14:2305-12. 2003..Furthermore, these data do not support earlier initiation of dialysis. Therefore, for patients without clinical indications for initiation of dialysis, the appropriate GFR level for initiation of dialysis is unknown...
Incorporating biological natural history in simulation models: empirical estimates of the progression of end-stage liver diseaseOguzhan Alagoz
Department of Industrial and Systems Engineering, University of Wisconsin, Madison, WI, USA
Med Decis Making 25:620-32. 2005..CONCLUSIONS: Cubic splines can be used to generate quantitative natural histories for individual patients with ESLD and may be useful for developing clinically robust microsimulation models of other diseases...
Validity and reliability of the Short Form-36 in cervical spondylotic myelopathyJoseph T King
Department of Neurological Surgery, Veteran s Administration Pittsburgh Healthcare System, Pennsylvania, USA
J Neurosurg 97:180-5. 2002..In this study the authors assessed the validity and reliability of the Medical Outcomes Study Short Form-36 (SF-36), a generic outcomes instrument, in a population of patients with cervical spondylotic myelopathy (CSM)...
A methodological framework for optimally reorganizing liver transplant regionsJames E Stahl
Department of Radiology and Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston 02114, USA
Med Decis Making 25:35-46. 2005..The United States is divided currently into 11 transplant regions, which vary in area and number of organ procurement organizations (OPOs). Region size affects organ travel time and organ viability at transplant...
Cost-effectiveness of low-molecular-weight heparin for treatment of pulmonary embolismDrahomir Aujesky
Division of General Internal Medicine, Department of Medicine, University of Pittsburgh, PA, USA
Chest 128:1601-10. 2005..Low-molecular-weight heparin (LMWH) appears to be safe and effective for treating pulmonary embolism (PE), but its cost-effectiveness has not been assessed...
Cost-effectiveness of head computed tomography in infants with possible inflicted traumatic brain injuryKristine A Campbell
Division of Safe and Healthy Families, Department of Pediatrics, University of Utah, 295 Chipeta Way, Box 581289, Salt Lake City, UT 84158, USA
Pediatrics 120:295-304. 2007..We undertook this study to estimate the cost-effectiveness of a policy of head computed tomography (CT) for inflicted traumatic brain injury in selected infants seen in an emergency department...
Estimating the rate of accumulating drug resistance mutations in the HIV genomeR Scott Braithwaite
Yale University School of Medicine Connecticut VA Healthcare System, 950 Campbell Avenue, West Haven, CT 06516, USA
Value Health 10:204-13. 2007..Our objective is to determine the accuracy with which mutation accumulation and other unmeasured parameters could be estimated during model calibration...
Brief intervention for medical inpatients with unhealthy alcohol use: a randomized, controlled trialRichard Saitz
Boston Medical Center and Boston University, Boston, Massachusetts 02118, USA
Ann Intern Med 146:167-76. 2007..The efficacy of brief intervention in reducing alcohol consumption is well established for selected outpatients but not for medical inpatients...
The value of medical spending in the United StatesR Scott Braithwaite
N Engl J Med 355:2492; author reply 2492. 2006
A framework for tailoring clinical guidelines to comorbidity at the point of careR Scott Braithwaite
Section of General Internal Medicine, Yale University School of Medicine, West Haven Veterans Affairs Connecticut Healthcare System, VACS 11 ACSL G, 950 Campbell Ave, West Haven, CT 06516, USA
Arch Intern Med 167:2361-5. 2007..Evidence is accumulating to suggest that clinical guidelines should be modified for patients with comorbidities, yet there is no quantitative and objective approach that considers benefits together with risks...
Increasing the efficiency of Monte Carlo cohort simulations with variance reduction techniquesSteven M Shechter
Department of Industrial Engineering, University of Pittsburgh, USA
Med Decis Making 26:550-3. 2006..However, most MC cohort simulations are well suited to the implementation of these techniques. The authors discuss the cost of implementation versus the benefit of reduced replications...
The cost-effectiveness of strategies to reduce mortality from an intentional release of aerosolized anthrax sporesR Scott Braithwaite
Section of General Internal Medicine, Yale University School of Medicine, 950 Campbell Avenue, West Haven, CT 06516, USA
Med Decis Making 26:182-93. 2006..Intentional exposures to aerosolized Bacillus anthracis spores have caused fatalities...
Willingness to pay for a quality-adjusted life year: implications for societal health care resource allocationJoseph T King
VA Connecticut Healthcare System, West Haven, CT, USA
Med Decis Making 25:667-77. 2005..Health-state preferences can be combined with willingness-to-pay (WTP) data to calculate WTP per quality-adjusted life year (QALY). The WTP/QALY ratios provide insight into societal valuations of expenditures for medical interventions...
Mental health, anxiety, and depression in patients with cerebral aneurysmsJoseph T King
Section of Neurosurgery, VA Connecticut Healthcare System, West Haven, Connecticut 06516, USA
J Neurosurg 103:636-41. 2005..Aneurysm disease and its treatment can have an adverse impact on mental health, yet the affects of cerebral aneurysms on general mental health, anxiety, and depression are poorly understood...
Adherence, virological and immunological outcomes for HIV-infected veterans starting combination antiretroviral therapiesR Scott Braithwaite
Section of General Internal Medicine, Department of Medicine, Yale University, 950 Campbell Avenue, West Haven, CT 06516, USA
AIDS 21:1579-89. 2007..We aimed to determine adherence, virological, and immunological outcomes one year after starting a first combination antiretroviral therapy (ART) regimen...
