Mark S Roberts

Summary

Affiliation: University of Pittsburgh
Country: USA

Publications

  1. ncbi request reprint Conceptualizing a model: a report of the ISPOR-SMDM Modeling Good Research Practices Task Force-2
    Mark Roberts
    Department of Health Policy and Management, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA 15213, USA
    Med Decis Making 32:678-89. 2012
  2. doi request reprint Conceptualizing a model: a report of the ISPOR-SMDM Modeling Good Research Practices Task Force--2
    Mark Roberts
    Department of Health Policy and Management, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA, USA
    Value Health 15:804-11. 2012
  3. doi request reprint Using mechanistic models to simulate comparative effectiveness trials of therapy and to estimate long-term outcomes in HIV care
    Mark S Roberts
    Department of Health Policy and Management, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
    Med Care 48:S90-5. 2010
  4. pmc Short-term mortality in acute pulmonary embolism: clot burden and signs of right heart dysfunction at CT pulmonary angiography
    Alessandro Furlan
    Department of Radiology, University of Pittsburgh Medical Center, 200 Lothrop St, Pittsburgh, PA 15213, USA
    Radiology 265:283-93. 2012
  5. pmc Cost-effectiveness of pneumococcal polysaccharide vaccine among healthcare workers during an influenza pandemic
    Kenneth J Smith
    Section of Decision Sciences and Clinical Systems Modeling, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Am J Manag Care 16:200-6. 2010
  6. pmc Development and validation of hospital "end-of-life" treatment intensity measures
    Amber E Barnato
    Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    Med Care 47:1098-105. 2009
  7. ncbi request reprint Quality of life utilities for pelvic inflammatory disease health states
    Kenneth J Smith
    Section of Decision Sciences and Clinical Systems Modeling, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
    Sex Transm Dis 35:307-11. 2008
  8. ncbi request reprint Cost-effectiveness of low-molecular-weight heparin for secondary prophylaxis of cancer-related venous thromboembolism
    Drahomir Aujesky
    Division of General Internal Medicine, Department of Medicine, University of Pittsburgh, Pennsylvania, USA
    Thromb Haemost 93:592-9. 2005
  9. ncbi request reprint A clinically based discrete-event simulation of end-stage liver disease and the organ allocation process
    Steven M Shechter
    Department of Industrial Engineering, University of Pittsburgh, Pennsylvania, USA
    Med Decis Making 25:199-209. 2005
  10. doi request reprint Economic evaluation of standing order programs for pneumococcal vaccination of hospitalized elderly patients
    Donald B Middleton
    Department of Family Medicine, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA 15232, USA
    Infect Control Hosp Epidemiol 29:385-94. 2008

Detail Information

Publications49

  1. ncbi request reprint Conceptualizing a model: a report of the ISPOR-SMDM Modeling Good Research Practices Task Force-2
    Mark Roberts
    Department of Health Policy and Management, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA 15213, USA
    Med Decis Making 32:678-89. 2012
    ....
  2. doi request reprint Conceptualizing a model: a report of the ISPOR-SMDM Modeling Good Research Practices Task Force--2
    Mark Roberts
    Department of Health Policy and Management, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA, USA
    Value Health 15:804-11. 2012
    ....
  3. doi request reprint Using mechanistic models to simulate comparative effectiveness trials of therapy and to estimate long-term outcomes in HIV care
    Mark S Roberts
    Department of Health Policy and Management, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
    Med Care 48:S90-5. 2010
    ..Mechanistic models of HIV infection can be used to conduct virtual therapeutic trials with the goal of predicting outcomes, some of which are long-term and may not fall within the time frame of a typical therapeutic trial...
  4. pmc Short-term mortality in acute pulmonary embolism: clot burden and signs of right heart dysfunction at CT pulmonary angiography
    Alessandro Furlan
    Department of Radiology, University of Pittsburgh Medical Center, 200 Lothrop St, Pittsburgh, PA 15213, USA
    Radiology 265:283-93. 2012
    ....
  5. pmc Cost-effectiveness of pneumococcal polysaccharide vaccine among healthcare workers during an influenza pandemic
    Kenneth J Smith
    Section of Decision Sciences and Clinical Systems Modeling, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Am J Manag Care 16:200-6. 2010
    ..To assess the usefulness and cost-effectiveness of pneumococcal polysaccharide vaccine (PPV) among healthcare workers compared with nonuse of PPV during an influenza pandemic...
  6. pmc Development and validation of hospital "end-of-life" treatment intensity measures
    Amber E Barnato
    Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    Med Care 47:1098-105. 2009
    ..Health care utilization among decedents is increasingly used as a measure of health care efficiency, but decedent-based measures may be biased estimates of care received by "dying" patients...
  7. ncbi request reprint Quality of life utilities for pelvic inflammatory disease health states
    Kenneth J Smith
    Section of Decision Sciences and Clinical Systems Modeling, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
    Sex Transm Dis 35:307-11. 2008
    ..Utilities for PID could have important implications on the cost-effectiveness of interventions to prevent and manage this disease...
  8. ncbi request reprint Cost-effectiveness of low-molecular-weight heparin for secondary prophylaxis of cancer-related venous thromboembolism
    Drahomir Aujesky
    Division of General Internal Medicine, Department of Medicine, University of Pittsburgh, Pennsylvania, USA
    Thromb Haemost 93:592-9. 2005
    ..However, because of the substantial pharmacy costs of extended low-molecular-weight heparin prophylaxis in the US, this treatment is relatively expensive compared with warfarin...
  9. ncbi request reprint A clinically based discrete-event simulation of end-stage liver disease and the organ allocation process
    Steven M Shechter
    Department of Industrial Engineering, University of Pittsburgh, Pennsylvania, USA
    Med Decis Making 25:199-209. 2005
    ..The objective of this article was to design a biologically based discrete-event simulation to test proposed changes in allocation policies...
  10. doi request reprint Economic evaluation of standing order programs for pneumococcal vaccination of hospitalized elderly patients
    Donald B Middleton
    Department of Family Medicine, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA 15232, USA
    Infect Control Hosp Epidemiol 29:385-94. 2008
    ..The purpose of this study was to estimate the cost-effectiveness of SOPs for pneumococcal polysaccharide vaccine (PPV) vaccination for patients 65 years of age or older in 2 types of hospital...
  11. doi request reprint Age, revaccination, and tolerance effects on pneumococcal vaccination strategies in the elderly: a cost-effectiveness analysis
    Kenneth J Smith
    University of Pittsburgh, Pittsburgh, PA, USA
    Vaccine 27:3159-64. 2009
    ..Revaccination strategies for the elderly are less cost-effective, particularly when prior vaccination and vaccine tolerance are considered...
  12. pmc Gray's time-varying coefficients model for posttransplant survival of pediatric liver transplant recipients with a diagnosis of cancer
    Yi Ren
    Department of Biostatistics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA
    Comput Math Methods Med 2013:719389. 2013
    ..While the Cox PH model provided reasonable average results in estimating covariate effects on posttransplant survival, the Gray model using piecewise constant penalized splines showed more details of how those effects change over time...
  13. pmc Cost-effectiveness analysis of efforts to reduce risk of type 2 diabetes and cardiovascular disease in southwestern Pennsylvania, 2005-2007
    Kenneth J Smith
    University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    Prev Chronic Dis 7:A109. 2010
    ..We assessed the cost-effectiveness of a community-based, modified Diabetes Prevention Program (DPP) designed to reduce risk factors for type 2 diabetes and cardiovascular disease...
  14. pmc Cost-effectiveness of implementing the chronic care model for diabetes care in a military population
    Shihchen Kuo
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    J Diabetes Sci Technol 5:501-13. 2011
    ..The CCM was implemented at U.S. Air Force Wilford Hall Medical Center through the Diabetes Outreach Clinic (DOC) in 2006, but its cost-effectiveness in this setting is unknown...
  15. pmc Use of dynamic microsimulation to predict disease progression in patients with pneumonia-related sepsis
    Gorkem Saka
    Department of Industrial Engineering, University of Pittsburgh, 3700 Ohara St, 3700 Benedum Hall, Pittsburgh, PA 15261, USA
    Crit Care 11:R65. 2007
    ....
  16. pmc The effect of pulmonary artery catheter use on costs and long-term outcomes of acute lung injury
    Gilles Clermont
    Clinical Research, Investigation, and Systems Modeling of Acute Illness Center, Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
    PLoS ONE 6:e22512. 2011
    ..central venous catheter (CVC). We explored if use of the PAC in ALI is justified by a beneficial cost-effectiveness profile...
  17. pmc Development of a coronary heart disease risk prediction model for type 1 diabetes: the Pittsburgh CHD in Type 1 Diabetes Risk Model
    Janice C Zgibor
    University of Pittsburgh, Department of Epidemiology, Graduate School of Public Health, USA
    Diabetes Res Clin Pract 88:314-21. 2010
    ..To create a coronary heart disease (CHD) risk prediction model specific to type 1 diabetes...
  18. pmc Is survival better at hospitals with higher "end-of-life" treatment intensity?
    Amber E Barnato
    Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA
    Med Care 48:125-32. 2010
    ..Concern regarding wide variations in spending and intensive care unit use for patients at the end of life hinges on the assumption that such treatment offers little or no survival benefit...
  19. ncbi request reprint Cardiovascular disease risk prediction in type 1 diabetes: accounting for the differences
    Kristine Ruppert
    Department of Epidemiology, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA, United States
    Diabetes Res Clin Pract 78:234-7. 2007
    ..005), non-HDLc (p=0.0005), WHR (p=0.003), and estimated glucose disposal rate (p=0.002) were associated. Risk factors not considered by the Framingham risk equation may account for the lack of fit and should be examined further...
  20. doi request reprint Alternative strategies for adult pneumococcal polysaccharide vaccination: a cost-effectiveness analysis
    Kenneth J Smith
    Section of Decision Sciences and Clinical Systems Modeling, School of Medicine, University of Pittsburgh, Pittsburgh, PA, United States
    Vaccine 26:1420-31. 2008
    ..PPV at ages 50/65 may be clinically and, depending on cost-effectiveness criterion used, economically favored over present vaccination recommendations...
  21. ncbi request reprint Cost-effectiveness of alternative outpatient pelvic inflammatory disease treatment strategies
    Kenneth J Smith
    Section of Decision Sciences and Clinical Systems Modeling, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
    Sex Transm Dis 34:960-6. 2007
    ..Effectiveness differences between outpatient pelvic inflammatory disease (PID) treatment regimens are uncertain, but significant differences in cost exist...
  22. pmc Factors associated with osteoporosis screening and recommendations for osteoporosis screening in older adults
    Smita Nayak
    School of Medicine, Department of Medicine, Division of General Internal Medicine, Section of Decision Sciences and Clinical Systems Modeling, University of Pittsburgh, Pittsburgh, PA 15213, USA
    J Gen Intern Med 24:585-91. 2009
    ..Osteoporosis screening rates are low, and it is unclear which patient factors are associated with screening and physician recommendations for screening...
  23. ncbi request reprint Increasing the efficiency of Monte Carlo cohort simulations with variance reduction techniques
    Steven M Shechter
    Department of Industrial Engineering, University of Pittsburgh, USA
    Med Decis Making 26:550-3. 2006
    ..However, most MC cohort simulations are well suited to the implementation of these techniques. The authors discuss the cost of implementation versus the benefit of reduced replications...
  24. ncbi request reprint Cost-effectiveness of low-molecular-weight heparin for treatment of pulmonary embolism
    Drahomir Aujesky
    Division of General Internal Medicine, Department of Medicine, University of Pittsburgh, PA, USA
    Chest 128:1601-10. 2005
    ..Low-molecular-weight heparin (LMWH) appears to be safe and effective for treating pulmonary embolism (PE), but its cost-effectiveness has not been assessed...
  25. pmc Cost-effectiveness of different screening strategies for osteoporosis in postmenopausal women
    Smita Nayak
    University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    Ann Intern Med 155:751-61. 2011
    ..The best strategies to screen postmenopausal women for osteoporosis are not clear...
  26. pmc Inflammatory markers at hospital discharge predict subsequent mortality after pneumonia and sepsis
    Sachin Yende
    The Clinical Research, Investigation, and Systems Modeling of Acute Illness CRISMA Laboratory, Department of Critical Care Medicine, Graduate School of Pubic Health, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
    Am J Respir Crit Care Med 177:1242-7. 2008
    ..Survivors of hospitalization for community-acquired pneumonia (CAP) are at increased risk of cardiovascular events, repeat infections, and death in the following months but the cause is unknown...
  27. ncbi request reprint Time from sexually transmitted infection acquisition to pelvic inflammatory disease development: influence on the cost-effectiveness of different screening intervals
    Kenneth J Smith
    School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Value Health 10:358-66. 2007
    ..Nevertheless, the time from STI acquisition to PID development, possibly an important factor to consider in screening interval choice, is unknown and its influence on the effectiveness and cost-effectiveness of screening is unclear...
  28. pmc Impact of generic alendronate cost on the cost-effectiveness of osteoporosis screening and treatment
    Smita Nayak
    Section of Decision Sciences and Clinical Systems Modeling, Division of General Internal Medicine, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America
    PLoS ONE 7:e32879. 2012
    ..The objective of this study was to investigate the impact of alendronate cost on the cost-effectiveness of osteoporosis screening and treatment in postmenopausal women...
  29. ncbi request reprint Hospitalization for pelvic inflammatory disease: a cost-effectiveness analysis
    Kenneth J Smith
    Section of Decision Sciences and Clinical Systems Modeling, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
    Sex Transm Dis 34:108-12. 2007
    ..Nulliparous women are frequently hospitalized for treatment of pelvic inflammatory disease (PID)...
  30. ncbi request reprint Procuring organ donors as a health investment: how much should we be willing to spend?
    John Mendeloff
    Graduate School of Public Health, Department of Health Policy and Management, University of Pittsburgh, Pittsburgh, PA 15260, USA
    Transplantation 78:1704-10. 2004
    ..Our objective was not only to see whether organ procurement is a "good" health investment, but also to clarify how much it is worth spending to obtain additional donors...
  31. ncbi request reprint Oral anticoagulation strategies after a first idiopathic venous thromboembolic event
    Drahomir Aujesky
    Division of General Internal Medicine, Department of Medicine, University of Pittsburgh, Pennsylvania, USA
    Am J Med 118:625-35. 2005
    ..We used decision analysis to evaluate clinical and economic outcomes of different anticoagulation strategies with warfarin...
  32. pmc Osteoporosis screening preferences of older adults
    Smita Nayak
    Department of Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA
    J Clin Densitom 12:279-86. 2009
    ..Many older individuals would prefer the "best" test for osteoporosis screening, and may be willing to travel or pay more to obtain a better test...
  33. ncbi request reprint Differences in access to liver transplantation: disease severity, waiting time, and transplantation center volume
    Jawad Ahmad
    Veterans Affairs Pittsburgh Healthcare System and University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    Ann Intern Med 146:707-13. 2007
    ..Allocation based on MELD scores should ensure that sicker patients receive transplants first regardless of transplantation center volume...
  34. ncbi request reprint Sequential medication strategies for postherpetic neuralgia: a cost-effectiveness analysis
    Kenneth J Smith
    Section of Decision Sciences and Clinical Systems Modeling, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    J Pain 8:396-404. 2007
    ..Our analysis supports the suggested treatment algorithm, with cost-effectiveness ratios within acceptable ranges for medications given sequentially, based on literature-based estimates of effectiveness and tolerability...
  35. ncbi request reprint Teaching medical decision modeling: a qualitative description of student errors and curriculum responses
    Kenneth J Smith
    Section of Decision Sciences and Clinical Systems Modeling, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    Med Decis Making 26:583-8. 2006
    ..Novice medical decision modelers are prone to errors. The purpose of this article is to describe the common errors committed by decision modeling students and the changes made to a structured decision modeling project course in response...
  36. ncbi request reprint Cost-effectiveness of newer treatment strategies for influenza
    Kenneth J Smith
    Section of Decision Sciences and Clinical Systems Modeling, Division of General Internal Medicine, and the Center for Research on Health Care, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    Am J Med 113:300-7. 2002
    ..Recent advances in the diagnosis and treatment of influenza, such as rapid testing and neuraminidase inhibitor therapy, are available, but their place in clinical practice and their cost-effectiveness have not been determined...
  37. doi request reprint Accuracy and reproducibility of blood clot burden quantification with pulmonary CT angiography
    Alessandro Furlan
    Department of Radiology, University of Pittsburgh Medical Center, PA 15213, USA
    AJR Am J Roentgenol 196:516-23. 2011
    ..The purpose of our study was to assess the accuracy and reproducibility of clot burden quantification with pulmonary CT angiography (CTA)...
  38. ncbi request reprint Preference-based quality of life measurement in patients with cervical spondylotic myelopathy
    Joseph T King
    Section of Neurosurgery, Surgical Service Line, Veterans Affairs Pittsburgh Healthcare System, Pittsburgh, PA, USA
    Spine (Phila Pa 1976) 29:1271-80. 2004
    ..Prospective cross-sectional observational cohort study...
  39. ncbi request reprint Cost-effectiveness of inhaled nitric oxide in the treatment of neonatal respiratory failure in the United States
    Derek C Angus
    Clinical Research, Investigation, and Systems Modeling of Acute Illness CRISMA Laboratory, Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
    Pediatrics 112:1351-60. 2003
    ..Our objective was to estimate the cost-effectiveness ratio of iNO in this population...
  40. ncbi request reprint Causal system modeling in chronic disease epidemiology: a proposal
    Roberta B Ness
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA
    Ann Epidemiol 17:564-8. 2007
    ..In all of these ways, they have the capability to advance the science of epidemiology...
  41. ncbi request reprint Simulation and critical care modeling
    Jennifer E Kreke
    Department of Industrial Engineering, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Curr Opin Crit Care 10:395-8. 2004
    ..Standard modeling techniques such as decision trees and statistical modeling have difficulty in capturing these interactions as the complexity of the problem increases...
  42. pmc The Effect of Race, Sex, and Insurance Status on Time-to-Listing Decisions for Liver Transplantation
    Cindy L Bryce
    Division of General Internal Medicine, Department of Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA
    J Transplant 2010:467976. 2010
    ..The early time period from diagnosis to listing for liver transplantation reveals unwanted variation related to demographics that jeopardizes overall fairness of organ allocation and needs to be further explored...
  43. ncbi request reprint Survival after liver transplantation in the United States: a disease-specific analysis of the UNOS database
    Mark S Roberts
    Section of Decision Sciences and Clinical Systems Modeling, Division of General Medicine, University of Pittsburgh School of Medicine, Center for Research on Health Care, Pittsburgh, PA 15213, USA
    Liver Transpl 10:886-97. 2004
    ..However, a significant portion of the difference in survival between diseases arises from differences in clinical characteristics at the time of transplantation...
  44. ncbi request reprint Deficiencies of cardiovascular risk prediction models for type 1 diabetes
    Janice C Zgibor
    Department of Epidemiology, University of Pittsburgh Graduate School of Public Health, USA
    Diabetes Care 29:1860-5. 2006
    ..Therefore, our objective was to examine the accuracy of Framingham and UKPDS models for predicting coronary heart disease (CHD) in a type 1 diabetic cohort...
  45. ncbi request reprint Expectations of groups versus pairs of attendings and residents about phone communications and bedside evaluation of hospitalized patients
    Gary Tabas
    Division of General Internal Medicine, Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15232, USA
    Teach Learn Med 17:217-27. 2005
    ..Residents covering attendings' patients must decide when to call the attending and when to evaluate patients at the bedside for new clinical events. Conflicts arise when residents and attendings disagree about these decisions...
  46. pmc Virtual epidemic in a virtual city: simulating the spread of influenza in a US metropolitan area
    Bruce Y Lee
    Section of Decision Sciences and Clinical Systems Modeling, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Transl Res 151:275-87. 2008
    ..Our simulation may serve as a virtual laboratory to better understand the way different factors and interventions affect the spread of influenza...
  47. ncbi request reprint Long-term HIV/AIDS survival estimation in the highly active antiretroviral therapy era
    Joseph T King
    Section of Neurosurgery, Surgical Service Line, VA Pittsburgh Healthcare System, Pittsburgh, Pennsylvania, USA
    Med Decis Making 23:9-20. 2003
    ..The authors construct a computer simulation model based on observational data to estimate long-term survival in a cohort of HIV/AIDS patients undergoing treatment with HAART...
  48. ncbi request reprint Health utility ratings for a spectrum of alcohol-related health states
    Kevin L Kraemer
    Center for Research on Health Care, Division of General Internal Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    Med Care 43:541-50. 2005
    ..Preference-based utility ratings for health conditions are important components of cost-utility analyses and population burden of disease estimates. However, utility ratings for alcohol problems have not been determined...
  49. ncbi request reprint Quality of life assessment with the medical outcomes study short form-36 among patients with cervical spondylotic myelopathy
    Joseph T King
    Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    Neurosurgery 52:113-20; discussion 121. 2003
    ..We used Medical Outcomes Study Short Form-36 (SF-36), a generic quality of life outcome-assessment instrument, to assess the quality of life among patients with CSM...