Jacques Robert

Summary

Affiliation: University of Rochester
Country: USA

Publications

  1. pmc Comparative study of tumorigenesis and tumor immunity in invertebrates and nonmammalian vertebrates
    Jacques Robert
    Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, NY 14642, United States jacques
    Dev Comp Immunol 34:915-25. 2010
  2. ncbi Development and characterization of a model system to study amphibian immune responses to iridoviruses
    Jennifer Gantress
    Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, NY 14642, USA
    Virology 311:254-62. 2003
  3. ncbi Involvement of nonclassical MHC class Ib molecules in heat shock protein-mediated anti-tumor responses
    Ana Goyos
    Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, NY 14642, USA
    Eur J Immunol 37:1494-501. 2007
  4. ncbi Localization and differential expression of activation-induced cytidine deaminase in the amphibian Xenopus upon antigen stimulation and during early development
    Shauna Marr
    Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, NY 14642, USA
    J Immunol 179:6783-9. 2007
  5. ncbi Minor histocompatibility antigen-specific MHC-restricted CD8 T cell responses elicited by heat shock proteins
    Jacques Robert
    Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, NY 14642, USA
    J Immunol 168:1697-703. 2002
  6. ncbi Xenopus laevis: a possible vector of Ranavirus infection?
    Jacques Robert
    Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, New York 14642, USA
    J Wildl Dis 43:645-52. 2007
  7. ncbi Phylogenetic conservation of glycoprotein 96 ability to interact with CD91 and facilitate antigen cross-presentation
    Jacques Robert
    Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, NY 14642, USA
    J Immunol 180:3176-82. 2008
  8. pmc Novel nonclassical MHC class Ib genes associated with CD8 T cell development and thymic tumors
    Ana Goyos
    Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, NY 14642, USA
    Mol Immunol 46:1775-86. 2009
  9. pmc Comparative and developmental study of the immune system in Xenopus
    Jacques Robert
    Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, New York, USA
    Dev Dyn 238:1249-70. 2009
  10. pmc The genus Xenopus as a multispecies model for evolutionary and comparative immunobiology of the 21st century
    Jacques Robert
    Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, NY 14642, United States
    Dev Comp Immunol 35:916-23. 2011

Collaborators

  • Nicholas Cohen
  • Gregory D Maniero
  • Yuko Ohta
  • Andrea Bottaro
  • Martin Flajnik
  • Ana Goyos
  • Jennifer Gantress
  • Heidi D Morales
  • Shauna Marr
  • Heidi Morales
  • Sergey Guselnikov
  • Thaminda Ramanayake
  • H Travis Ichikawa
  • Laura Rau
  • Lara Abramowitz
  • Jessica Sowa
  • Jacqueline Gertz
  • Ashley Vogel
  • David A L Simon
  • John G Frelinger
  • Michelle Cooper
  • Edith M Lord
  • Sanjay B Maggirwar
  • Lynn F Sniderhan
  • Asiya S Chida
  • Hristina Nedelkovska
  • Geoffrey S C Dance
  • Pinwei Huang
  • Joseph E Wedekind
  • Jurgen Bachl
  • Andrew T Torelli
  • Shauna H Marr
  • Mark P Sowden
  • Harold C Smith
  • Alma Muharemagic
  • Rebecca Stewart
  • Trudy Horton
  • Alisa Bell
  • John Horton

Detail Information

Publications23

  1. pmc Comparative study of tumorigenesis and tumor immunity in invertebrates and nonmammalian vertebrates
    Jacques Robert
    Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, NY 14642, United States jacques
    Dev Comp Immunol 34:915-25. 2010
    ....
  2. ncbi Development and characterization of a model system to study amphibian immune responses to iridoviruses
    Jennifer Gantress
    Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, NY 14642, USA
    Virology 311:254-62. 2003
    ....
  3. ncbi Involvement of nonclassical MHC class Ib molecules in heat shock protein-mediated anti-tumor responses
    Ana Goyos
    Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, NY 14642, USA
    Eur J Immunol 37:1494-501. 2007
    ..This study provides in vitro and in vivo evidence of the evolutionary conservation of class Ib involvement in anti-tumor CD8+ T cell responses...
  4. ncbi Localization and differential expression of activation-induced cytidine deaminase in the amphibian Xenopus upon antigen stimulation and during early development
    Shauna Marr
    Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, NY 14642, USA
    J Immunol 179:6783-9. 2007
    ..This study highlights the conserved involvement of XlAID during Ag-dependent B cell responses in Xenopus but also suggests another role in B cell differentiation earlier in ontogeny...
  5. ncbi Minor histocompatibility antigen-specific MHC-restricted CD8 T cell responses elicited by heat shock proteins
    Jacques Robert
    Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, NY 14642, USA
    J Immunol 168:1697-703. 2002
    ..e., gp96 purified from normal tissue also generates a significant antitumor response); this suggests a prominent contribution of an innate type of response in the absence of MHC class I Ags...
  6. ncbi Xenopus laevis: a possible vector of Ranavirus infection?
    Jacques Robert
    Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, New York 14642, USA
    J Wildl Dis 43:645-52. 2007
    ..These results suggest that FV3 can become quiescent in resistant species such as Xenopus, thereby making these species potential viral reservoirs...
  7. ncbi Phylogenetic conservation of glycoprotein 96 ability to interact with CD91 and facilitate antigen cross-presentation
    Jacques Robert
    Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, NY 14642, USA
    J Immunol 180:3176-82. 2008
    ..The persistence of this biological process for >350 million years that separate mammals and amphibians from a common ancestor strongly supports the proposition that gp96 and CD91 are critically involved in immune surveillance...
  8. pmc Novel nonclassical MHC class Ib genes associated with CD8 T cell development and thymic tumors
    Ana Goyos
    Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, NY 14642, USA
    Mol Immunol 46:1775-86. 2009
    ..These data provide the first evidence of the expression of any class Ib genes in Xenopus larvae, and suggests evolutionary relationships between certain class Ib genes, malignancy and CD8 T cell ontogeny...
  9. pmc Comparative and developmental study of the immune system in Xenopus
    Jacques Robert
    Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, New York, USA
    Dev Dyn 238:1249-70. 2009
    ..laevis and S. tropicalis, as well as the whole Xenopus genus. Developmental Dynamics 238:1249-1270, 2009. (c) 2009 Wiley-Liss, Inc...
  10. pmc The genus Xenopus as a multispecies model for evolutionary and comparative immunobiology of the 21st century
    Jacques Robert
    Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, NY 14642, United States
    Dev Comp Immunol 35:916-23. 2011
    ..We also discuss the rich potential of the species with different degrees of polypoidy resulting from whole genome-wide duplication of the Xenopodinae subfamily as a model to study regulation at the genome level...
  11. pmc Waterborne infectivity of the Ranavirus frog virus 3 in Xenopus laevis
    Jacques Robert
    Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, NY 14642, USA
    Virology 417:410-7. 2011
    ..These data highlight the efficiency of FV3 infectivity by the water route and the ability of FV3 to adapt to its hosts...
  12. pmc Characterization of primary and memory CD8 T-cell responses against ranavirus (FV3) in Xenopus laevis
    Heidi D Morales
    Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, NY 14642, USA
    J Virol 81:2240-8. 2007
    ..These results provide in vivo evidence of protective antigen-dependent CD8+ T-cell proliferation, recognition, and memory in fighting a natural pathogen in Xenopus...
  13. ncbi Evolution of heat shock protein and immunity
    Jacques Robert
    Department of Microbiology and Immunology, University of Rochester Medical Center, Box 672 601, Elmwood Avenue, Rochester, NY 14642, USA
    Dev Comp Immunol 27:449-64. 2003
    ..Data from studies with the frog Xenopus support this proposition...
  14. ncbi Xenopus as an experimental model for studying evolution of hsp--immune system interactions
    Jacques Robert
    Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, NY 14642, USA
    Methods 32:42-53. 2004
    ..Finally, techniques to study modalities of expression of the endoplasmic reticulum resident gp96 at the cell surface of tumor and normal lymphocytes are considered...
  15. ncbi Anti-tumor MHC class Ia-unrestricted CD8 T cell cytotoxicity elicited by the heat shock protein gp96
    Ana Goyos
    Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, NY 14642, USA
    Eur J Immunol 34:2449-58. 2004
    ....
  16. ncbi Adaptive immunity and histopathology in frog virus 3-infected Xenopus
    Jacques Robert
    Department of Microbiology and Immunology, University of Rochester Medical Center, 601 Elmwood Avenue, Rochester, NY 14642, USA
    Virology 332:667-75. 2005
    ....
  17. ncbi CD91 up-regulates upon immune stimulation in Xenopus adult but not larval peritoneal leukocytes
    Shauna Marr
    Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, NY, 14642, USA
    Immunogenetics 56:735-42. 2005
    ..These data are in agreement with a conserved role of CD91 in immunity...
  18. pmc Innate immune responses and permissiveness to ranavirus infection of peritoneal leukocytes in the frog Xenopus laevis
    Heidi D Morales
    Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, NY 14642, USA
    J Virol 84:4912-22. 2010
    ..This suggests that although PLs are actively involved in anti-FV3 immune responses, some of these cells can be permissive and harbor quiescent, asymptomatic FV3...
  19. ncbi Structural phylogenetic analysis of activation-induced deaminase function
    H Travis Ichikawa
    Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    J Immunol 177:355-61. 2006
    ....
  20. ncbi Identification and characterization of Xenopus CD8+ T cells expressing an NK cell-associated molecule
    Laura Rau
    Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, NY 14642, USA
    Eur J Immunol 32:1574-83. 2002
    ..Taken together, these new data suggest that regulation of CD8+ T cell activity involving NK cell-associated molecules is a general and evolutionarily ancient phenomenon...
  21. pmc Bacterial stimulation upregulates the surface expression of the stress protein gp96 on B cells in the frog Xenopus
    Heidi Morales
    Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, NY 14642, USA
    Cell Stress Chaperones 8:265-71. 2003
    ....
  22. pmc Tumorigenesis and anti-tumor immune responses in Xenopus
    Ana Goyos
    Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, NY 14642, USA
    Front Biosci 14:167-76. 2009
    ....
  23. ncbi In vivo study of T-cell responses to skin alloantigens in Xenopus using a novel whole-mount immunohistology method
    Thaminda Ramanayake
    Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, NY 14642, USA
    Transplantation 83:159-66. 2007
    ..The African clawed frog, Xenopus, is a widely used comparative model for studying the immune response to transplantation antigens...