Nadia R Roan

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Semen-mediated enhancement of HIV infection is donor-dependent and correlates with the levels of SEVI
    Kyeong Ae Kim
    Institute of Molecular Virology, University Hospital Ulm, 89081 Ulm, Germany
    Retrovirology 7:55. 2010
  2. ncbi request reprint A seminal finding for understanding HIV transmission
    Nadia R Roan
    Gladstone Institute of Virology and Immunology, University of California, San Francisco, 1650 Owens Street, San Francisco, CA 94158, USA
    Cell 131:1044-6. 2007
  3. pmc Aminoquinoline surfen inhibits the action of SEVI (semen-derived enhancer of viral infection)
    Nadia R Roan
    Gladstone Institute of Virology and Immunology, University of California, San Francisco, California 94158, USA
    J Biol Chem 285:1861-9. 2010
  4. pmc Peptides released by physiological cleavage of semen coagulum proteins form amyloids that enhance HIV infection
    Nadia R Roan
    Gladstone Institute of Virology and Immunology, University of California, San Francisco, CA 94158, USA
    Cell Host Microbe 10:541-50. 2011
  5. pmc The cationic properties of SEVI underlie its ability to enhance human immunodeficiency virus infection
    Nadia R Roan
    Gladstone Institute of Virology and Immunology, University of California, P O Box 419100, San Francisco, CA 94141 9100, USA
    J Virol 83:73-80. 2009
  6. pmc Seminal plasma induces global transcriptomic changes associated with cell migration, proliferation and viability in endometrial epithelial cells and stromal fibroblasts
    Joseph C Chen
    Center for Reproductive Sciences, Department of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Francisco, CA, USA
    Hum Reprod 29:1255-70. 2014
  7. doi request reprint Conquering sexually transmitted diseases
    Michael N Starnbach
    Department of Microbiology and Molecular Genetics, Harvard Medical School, 200 Longwood Avenue, Boston, Massachusetts 02115, USA
    Nat Rev Immunol 8:313-7. 2008

Collaborators

  • Frank Kirchhoff
  • Warner Greene
  • Nathalie Arhel
  • Joseph C Chen
  • Kyeong Ae Kim
  • Michael N Starnbach
  • Terhi T Piltonen
  • Simon Chu
  • David W Erikson
  • Brittni A Johnson
  • Juan C Irwin
  • Nargis Kohgadai
  • Fatima Barragan
  • Linda C Giudice
  • Adam Burgener
  • Maral Yolamanova
  • George M Shaw
  • Nathalie Dejucq-Rainsford
  • Onofrio Zirafi
  • Ludger Staendker
  • Wolf Georg Forssmann
  • Jan Munch
  • Beatrice H Hahn

Detail Information

Publications7

  1. pmc Semen-mediated enhancement of HIV infection is donor-dependent and correlates with the levels of SEVI
    Kyeong Ae Kim
    Institute of Molecular Virology, University Hospital Ulm, 89081 Ulm, Germany
    Retrovirology 7:55. 2010
    ..Despite its importance for the global spread of HIV-1, however, the effect of semen on virus infection is controversial...
  2. ncbi request reprint A seminal finding for understanding HIV transmission
    Nadia R Roan
    Gladstone Institute of Virology and Immunology, University of California, San Francisco, 1650 Owens Street, San Francisco, CA 94158, USA
    Cell 131:1044-6. 2007
    ..As a potential explanation for this discrepancy, M√ľnch et al. (2007) now identify and characterize a factor found in human semen that under certain conditions can enhance HIV infectivity by more than 100,000-fold...
  3. pmc Aminoquinoline surfen inhibits the action of SEVI (semen-derived enhancer of viral infection)
    Nadia R Roan
    Gladstone Institute of Virology and Immunology, University of California, San Francisco, California 94158, USA
    J Biol Chem 285:1861-9. 2010
    ..Because SEVI can increase HIV infectivity by several orders of magnitude, supplementing current HIV microbicide candidates with SEVI inhibitors, such as surfen, might greatly increase their potency...
  4. pmc Peptides released by physiological cleavage of semen coagulum proteins form amyloids that enhance HIV infection
    Nadia R Roan
    Gladstone Institute of Virology and Immunology, University of California, San Francisco, CA 94158, USA
    Cell Host Microbe 10:541-50. 2011
    ..Semen thus harbors distinct amyloidogenic peptides derived from different precursor proteins that commonly enhance HIV infection and likely contribute to HIV transmission...
  5. pmc The cationic properties of SEVI underlie its ability to enhance human immunodeficiency virus infection
    Nadia R Roan
    Gladstone Institute of Virology and Immunology, University of California, P O Box 419100, San Francisco, CA 94141 9100, USA
    J Virol 83:73-80. 2009
    ..Combinations of agents that neutrale SEVI action and produce HIV virucidal effects are an attractive future direction for microbicide development...
  6. pmc Seminal plasma induces global transcriptomic changes associated with cell migration, proliferation and viability in endometrial epithelial cells and stromal fibroblasts
    Joseph C Chen
    Center for Reproductive Sciences, Department of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Francisco, CA, USA
    Hum Reprod 29:1255-70. 2014
    ..How does seminal plasma (SP) affect the transcriptome of human primary endometrial epithelial cells (eEC) and stromal fibroblasts (eSF)?..
  7. doi request reprint Conquering sexually transmitted diseases
    Michael N Starnbach
    Department of Microbiology and Molecular Genetics, Harvard Medical School, 200 Longwood Avenue, Boston, Massachusetts 02115, USA
    Nat Rev Immunol 8:313-7. 2008
    ....