Nadia R Roan

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Semen-mediated enhancement of HIV infection is donor-dependent and correlates with the levels of SEVI
    Kyeong Ae Kim
    Institute of Molecular Virology, University Hospital Ulm, 89081 Ulm, Germany
    Retrovirology 7:55. 2010
  2. ncbi request reprint A seminal finding for understanding HIV transmission
    Nadia R Roan
    Gladstone Institute of Virology and Immunology, University of California, San Francisco, 1650 Owens Street, San Francisco, CA 94158, USA
    Cell 131:1044-6. 2007
  3. pmc Aminoquinoline surfen inhibits the action of SEVI (semen-derived enhancer of viral infection)
    Nadia R Roan
    Gladstone Institute of Virology and Immunology, University of California, San Francisco, California 94158, USA
    J Biol Chem 285:1861-9. 2010
  4. pmc Peptides released by physiological cleavage of semen coagulum proteins form amyloids that enhance HIV infection
    Nadia R Roan
    Gladstone Institute of Virology and Immunology, University of California, San Francisco, CA 94158, USA
    Cell Host Microbe 10:541-50. 2011
  5. pmc The cationic properties of SEVI underlie its ability to enhance human immunodeficiency virus infection
    Nadia R Roan
    Gladstone Institute of Virology and Immunology, University of California, P O Box 419100, San Francisco, CA 94141 9100, USA
    J Virol 83:73-80. 2009
  6. doi request reprint Conquering sexually transmitted diseases
    Michael N Starnbach
    Department of Microbiology and Molecular Genetics, Harvard Medical School, 200 Longwood Avenue, Boston, Massachusetts 02115, USA
    Nat Rev Immunol 8:313-7. 2008

Collaborators

  • Frank Kirchhoff
  • Warner Greene
  • Nathalie Arhel
  • Kyeong Ae Kim
  • Michael N Starnbach
  • Onofrio Zirafi
  • Wolf Georg Forssmann
  • Beatrice H Hahn
  • Adam Burgener
  • Maral Yolamanova
  • George M Shaw
  • Nathalie Dejucq-Rainsford
  • Ludger Staendker
  • Jan Munch

Detail Information

Publications6

  1. pmc Semen-mediated enhancement of HIV infection is donor-dependent and correlates with the levels of SEVI
    Kyeong Ae Kim
    Institute of Molecular Virology, University Hospital Ulm, 89081 Ulm, Germany
    Retrovirology 7:55. 2010
    ..Despite its importance for the global spread of HIV-1, however, the effect of semen on virus infection is controversial...
  2. ncbi request reprint A seminal finding for understanding HIV transmission
    Nadia R Roan
    Gladstone Institute of Virology and Immunology, University of California, San Francisco, 1650 Owens Street, San Francisco, CA 94158, USA
    Cell 131:1044-6. 2007
    ..As a potential explanation for this discrepancy, M√ľnch et al. (2007) now identify and characterize a factor found in human semen that under certain conditions can enhance HIV infectivity by more than 100,000-fold...
  3. pmc Aminoquinoline surfen inhibits the action of SEVI (semen-derived enhancer of viral infection)
    Nadia R Roan
    Gladstone Institute of Virology and Immunology, University of California, San Francisco, California 94158, USA
    J Biol Chem 285:1861-9. 2010
    ..Because SEVI can increase HIV infectivity by several orders of magnitude, supplementing current HIV microbicide candidates with SEVI inhibitors, such as surfen, might greatly increase their potency...
  4. pmc Peptides released by physiological cleavage of semen coagulum proteins form amyloids that enhance HIV infection
    Nadia R Roan
    Gladstone Institute of Virology and Immunology, University of California, San Francisco, CA 94158, USA
    Cell Host Microbe 10:541-50. 2011
    ..Semen thus harbors distinct amyloidogenic peptides derived from different precursor proteins that commonly enhance HIV infection and likely contribute to HIV transmission...
  5. pmc The cationic properties of SEVI underlie its ability to enhance human immunodeficiency virus infection
    Nadia R Roan
    Gladstone Institute of Virology and Immunology, University of California, P O Box 419100, San Francisco, CA 94141 9100, USA
    J Virol 83:73-80. 2009
    ..Combinations of agents that neutrale SEVI action and produce HIV virucidal effects are an attractive future direction for microbicide development...
  6. doi request reprint Conquering sexually transmitted diseases
    Michael N Starnbach
    Department of Microbiology and Molecular Genetics, Harvard Medical School, 200 Longwood Avenue, Boston, Massachusetts 02115, USA
    Nat Rev Immunol 8:313-7. 2008
    ....