Research Topics
Genomes and GenesSpecies | Beate R RitzSummaryAffiliation: University of California Country: USA Publications
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Publications
α-Synuclein genetic variants predict faster motor symptom progression in idiopathic Parkinson diseaseBeate Ritz
Department of Epidemiology, University of California Los Angeles, Los Angeles, California, United States of America
PLoS ONE 7:e36199. 2012..SNCA may be a promising target for therapies and may help identify patients who will benefit most from early interventions. This is the first study to link SNCA to motor symptom decline in a longitudinal progression study...
An effective and efficient approach for manually improving geocoded dataDaniel W Goldberg
Department of Computer Science, University of Southern California, Los Angeles, CA, USA
Int J Health Geogr 7:60. 2008..The present work investigates the time and effort required to correct geocodes contained in five health-related datasets that represent examples of data commonly used in Health GIS...
Traffic-related air toxics and preterm birth: a population-based case-control study in Los Angeles County, CaliforniaMichelle Wilhelm
Department of Epidemiology, School of Public Health, University of California, Los Angeles, CA, USA
Environ Health 10:89. 2011..We used three exposure data sources to examine risks of preterm birth in Los Angeles women when exposed to high levels of traffic-related air pollutants--including specific toxics--during pregnancy...
Longitudinal variability of time-location/activity patterns of population at different ages: a longitudinal study in CaliforniaXiangmei Wu
Department of Public Health Sciences, University of California, Davis, CA, USA
Environ Health 10:80. 2011..This study was designed to evaluate longitudinal variations in human time-activity patterns...
Study of Use of Products and Exposure-Related Behaviors (SUPERB): study design, methods, and demographic characteristics of cohortsIrva Hertz-Picciotto
Department of Public Health Sciences, School of Medicine, University of California, Davis, One Shields Avenue, Davis, CA 95616, USA
Environ Health 9:54. 2010....
Statin use and Parkinson's disease in DenmarkBeate Ritz
Department of Epidemiology, UCLA School of Public Health, Los Angeles, California 90095 1772, USA
Mov Disord 25:1210-6. 2010..Yet, further investigations into the contributions of intensity, duration, and lag periods of statin use may still be warranted...
Geographic model and biomarker-derived measures of pesticide exposure and Parkinson's diseaseBeate Ritz
UCLA School of Public Health, Los Angeles, CA 90095 1772, USA
Ann N Y Acad Sci 1076:378-87. 2006..Our environmental GIS-PUR-based approach appears to provide a valid model for assessing residential exposures to agricultural pesticides...
Assessment of environmental exposures from agricultural pesticides in childhood leukaemia studies: challenges and opportunitiesBeate Ritz
Department of Epidemiology, Center for Occupational and Environmental Health, UCLA, School of Public Health, Box 951772, 650 Charles E Young Drive, Los Angeles, CA 90095 1772, USA
Radiat Prot Dosimetry 132:148-55. 2008..Results from exposure validation and simulation studies and exposure measurement error issues are discussed...
Pooled analysis of tobacco use and risk of Parkinson diseaseBeate Ritz
Department of Epidemiology and Environmental Health Sciences, UCLA School of Public Health, 650 Charles Young Smith Dr S, Los Angeles, CA 90095 1772, USA
Arch Neurol 64:990-7. 2007..This comprehensive assessment of the apparent reduced risk of PD associated with smoking may provide important leads for treatment and prevention...
Ambient air pollution and preterm birth in the environment and pregnancy outcomes study at the University of California, Los AngelesBeate Ritz
Department of Epidemiology, School of Public Health, University of California, Los Angeles, CA 90095, USA
Am J Epidemiol 166:1045-52. 2007..These results confirm the importance of reducing exposure misclassification when evaluating the effect of traffic-related pollutants that vary spatially...
Ambient air pollution and adverse birth outcomes: methodologic issues in an emerging fieldBeate Ritz
Department of Epidemiology, School of Public Health, University of California, Los Angeles, CA 90095 1772, USA
Basic Clin Pharmacol Toxicol 102:182-90. 2008..Investigating biological mechanisms (e.g. using ultrasound measurements and biomarkers for hypothesized pathways) is an important remaining issue...
Dopamine transporter genetic variants and pesticides in Parkinson's diseaseBeate R Ritz
Department of Epidemiology, Center for Occupational and Environmental Health, UCLA School of Public Health, University of California at Los Angeles, Los Angeles, California 90095 1772, USA
Environ Health Perspect 117:964-9. 2009..Research suggests that independent and joint effects of genetic variability in the dopamine transporter (DAT) locus and pesticides may influence Parkinson's disease (PD) risk...
Air pollution and infant death in southern California, 1989-2000Beate Ritz
Department of Epidemiology, School of Public Health, University of California, Los Angeles, PO Box 951772, 650 Charles E Young Dr, Los Angeles, California 90095 1772, USA
Pediatrics 118:493-502. 2006..We evaluated the influence of outdoor air pollution on infant death in the South Coast Air Basin of California, an area characterized by some of the worst air quality in the United States...
Estimated effects of hydrazine exposure on cancer incidence and mortality in aerospace workersBeate Ritz
Department of Epidemiology, School of Public Health, University of California Los Angeles, 90095 1772, USA
Epidemiology 17:154-61. 2006..Animal studies suggest that hydrazine is a lung carcinogen, but human studies have been rare, rather small, and limited to cancer mortality...
L-type calcium channel blockers and Parkinson disease in DenmarkBeate Ritz
Department of Epidemiology, University of California at Los Angeles School of Public Health, Los Angeles, CA, USA
Ann Neurol 67:600-6. 2010....
Environmental toxins and neurodegenerative diseases: a challenge for epidemiologistsBeate Ritz
University of California at Los Angeles, School of Public Health, Box 951772, 650 Charles E. Young Drive, 90095-1772, USA
Epidemiology 17:2-3. 2006
Effects of exposure to external ionizing radiation on cancer mortality in nuclear workers monitored for radiation at Rocketdyne/Atomics InternationalB Ritz
Department of Epidemiology, UCLA School of Public Health 90095 1772, USA
Am J Ind Med 35:21-31. 1999....
The effects of internal radiation exposure on cancer mortality in nuclear workers at Rocketdyne/Atomics InternationalB Ritz
Department of Epidemiology, School of Public Health, University of California Los Angeles, Los Angeles, California 90095 1772, USA
Environ Health Perspect 108:743-51. 2000..However, causal inferences require replication of our results in other populations or confirmation with an extended follow-up of this cohort...
Ambient air pollution and risk of birth defects in Southern CaliforniaBeate Ritz
Department of Epidemiology, School of Public Health, University of California, Los Angeles, Los Angeles, CA 90095 1772, USA
Am J Epidemiol 155:17-25. 2002..Confirmation by further studies is needed...
Can lessons from public health disease surveillance be applied to environmental public health tracking?Beate Ritz
Department of Epidemiology, University of California, Los Angeles, California, USA
Environ Health Perspect 113:243-9. 2005..Key words: environmental health, evaluation, intervention, registries, surveillance...
Follow-up of neck and shoulder pain among sewing machine operators: The Los Angeles garment studyPin Chieh Wang
Department of Epidemiology, School of Public Health, University of California, Los Angeles, California 90095 1772, USA
Am J Ind Med 53:352-60. 2010..The aim of the present study is to explore factors affecting or modifying self-reported neck/shoulder pain in sewing machine operators...
A randomized controlled trial of chair interventions on back and hip pain among sewing machine operators: the los angeles garment studyPin Chieh Wang
Department of Epidemiology, School of Public Health, University of California, Los Angeles, California, USA
J Occup Environ Med 50:255-62. 2008..Determine whether an adjustable chair with a curved or a flat seat pan improved monthly back and hip pain scores in sewing machine operators...
Residential proximity to traffic and adverse birth outcomes in Los Angeles county, California, 1994-1996Michelle Wilhelm
Department of Epidemiology, School of Public Health, UCLA, Los Angeles, California 90095-1772, USA
Environ Health Perspect 111:207-16. 2003..Our previous research and these latest results suggest exposure to traffic-related pollutants may be important...
Parkinson's disease and residential exposure to maneb and paraquat from agricultural applications in the central valley of CaliforniaSadie Costello
Department of Environmental Health Sciences, University of California, Berkeley, 94720 7360, USA
Am J Epidemiol 169:919-26. 2009..17, 95% CI: 1.15, 15.16) in 1974-1989. This study provides evidence that exposure to a combination of maneb and paraquat increases PD risk, particularly in younger subjects and/or when exposure occurs at younger ages...
Self-reported pain and physical signs for musculoskeletal disorders in the upper body region among Los Angeles garment workersPin Chieh Wang
Department of Epidemiology, School of Public Health, University of California, Los Angeles, CA 90095 1772, USA
Work 34:79-87. 2009..Also, in order to evaluate the success of an intervention, screening, or surveillance program for work related MSDs, it is important to define clearly which outcome measure best to employ...
Historical pesticide exposure in California using pesticide use reports and land-use surveys: an assessment of misclassification error and biasRudolph P Rull
Department of Epidemiology, School of Public Health, University of California-Los Angeles, Los Angeles, California 90095-1772, USA
Environ Health Perspect 111:1582-9. 2003..These results underscore the importance of increasing the spatiotemporal resolution of pesticide exposure models to minimize misclassification...
Local variations in CO and particulate air pollution and adverse birth outcomes in Los Angeles County, California, USAMichelle Wilhelm
Department of Epidemiology, School of Public Health, University of California, Los Angeles, CA 90095, USA
Environ Health Perspect 113:1212-21. 2005..In addition, they confirm our suspicions about having to address local heterogeneity for these pollutants in Los Angeles...
Association between local traffic-generated air pollution and preeclampsia and preterm delivery in the south coast air basin of CaliforniaJun Wu
Program in Public Health, College of Health Sciences, University of California, Irvine, California 92697 7555, USA
Environ Health Perspect 117:1773-9. 2009..Increasing evidence suggests that air pollution adversely affects pregnancy outcomes. Yet few studies have examined how local traffic-generated emissions affect preeclampsia in addition to preterm birth...
Paraoxonase 1, agricultural organophosphate exposure, and Parkinson diseaseAngelika D Manthripragada
Department of Epidemiology, UCLA School of Public Health, Los Angeles, CA 90095, USA
Epidemiology 21:87-94. 2010..Susceptibility to pesticides may be modified by genetic variants of xenobiotic enzymes, such as paraoxonase, that play a role in metabolizing some organophosphates...
Predicting traffic-related air pollution in Los Angeles using a distance decay regression selection strategyJason G Su
Division of Environmental Health Sciences, School of Public Health, University of California, Berkeley, USA
Environ Res 109:657-70. 2009..g., > 5000 m from expressway) and high background concentrations in certain geographic areas. This paper represents the first attempt to model traffic-related air pollutants at a fine scale within such a complex and large urban region...
Adjustment for response bias via two-phase analysis: an applicationKatherine J Hoggatt
Department of Epidemiology, University of Michigan, Ann Arbor, MI 48109, USA
Epidemiology 20:872-9. 2009..We use data from a study of air pollution and birth outcomes to illustrate how a 2-phase analysis can yield less biased and more precise results...
Paternal support and preterm birth, and the moderation of effects of chronic stress: a study in Los Angeles county mothersJo Kay C Ghosh
Department of Epidemiology, University of California, Los Angeles, 650 Charles E Young Dr South, CHS 71 254, Los Angeles, CA 90095 1772, USA
Arch Womens Ment Health 13:327-38. 2010..15 [95%CI 0.92, 5.03]), but women with greater support had no increased risk with moderate-to-high chronic stress (OR 1.13 [95%CI 0.94, 1.35]). Paternal support may moderate the effects of chronic stress on the risk of preterm delivery...
Exposure to polycyclic aromatic hydrocarbons and missed abortion in early pregnancy in a Chinese populationJun Wu
Program in Public Health and Department of Epidemiology, College of Health Sciences, University of California, Irvine, California, USA
Sci Total Environ 408:2312-8. 2010..High PAH exposure has been associated with low birth weight, intrauterine growth restriction, and preterm birth, but little is known about its impact on adverse outcomes in early pregnancy such as in-utero fetal death...
Estimated effects of solvents and mineral oils on cancer incidence and mortality in a cohort of aerospace workersYingxu Zhao
Department of Epidemiology, School of Public Health, UCLA, Los Angeles, California, USA
Am J Ind Med 48:249-58. 2005..These results and the increases we observed for TCE and kidney cancers are consistent with findings of previous studies...
Traffic and outdoor air pollution levels near residences and poorly controlled asthma in adultsYing Ying Meng
UCLA Center for Health Policy Research, Los Angeles, California 90024, USA
Ann Allergy Asthma Immunol 98:455-63. 2007..Air pollution may exacerbate asthma...
Nested case-control study of occupational physical activity and prostate cancer among workers using a job exposure matrixAnusha Krishnadasan
Department of Epidemiology, School of Public Health, University of California Los Angeles, CA, USA
Cancer Causes Control 19:107-14. 2008....
Statin use and the risk of Parkinson diseaseAngelika D Wahner
Department of Epidemiology, UCLA School of Public Health, 650 Charles E Young Drive, Los Angeles, CA 90095 1772, USA
Neurology 70:1418-22. 2008..To investigate associations between statin (3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor) use and Parkinson disease (PD)...
Outdoor air pollution and uncontrolled asthma in the San Joaquin Valley, CaliforniaYing Ying Meng
UCLA Center for Health Policy Research, Los Angeles, California, USA
J Epidemiol Community Health 64:142-7. 2010..Using California Health Interview Survey data, the authors examined associations between air pollution and asthma morbidity in this region...
Nested case-control study of occupational chemical exposures and prostate cancer in aerospace and radiation workersAnusha Krishnadasan
Department of Epidemiology, School of Public Health, University of California, Los Angeles, CA, USA
Am J Ind Med 50:383-90. 2007..Previous studies examining associations suffered from limitations including the reliance on mortality data and inadequate exposure assessment...
Preterm birth: the interaction of traffic-related air pollution with economic hardship in Los Angeles neighborhoodsNinez A Ponce
Department of Health Services, School of Public Health, University of California at Los Angeles, CA 90095 1772, USA
Am J Epidemiol 162:140-8. 2005....
Validation of self-reported proximity to agricultural crops in a case-control study of neural tube defectsRudolph P Rull
Center for Health Policy Research, University of California, Los Angeles, CA 90024, USA
J Expo Sci Environ Epidemiol 16:147-55. 2006..These results suggest differential reporting between case and control mothers as well as an influence from maternal demographic characteristics on reporting accuracy...
Outdoor air pollution, family and neighborhood environment, and asthma in LA FANS childrenMichelle Wilhelm
Department of Epidemiology, School of Public Health, UCLA, Los Angeles, CA 90095 1772, USA
Health Place 15:25-36. 2009..Pollutant levels were not correlated with neighborhood support. Even after adjustment for social environment characteristics, LA FANS children living in high O(3), PM(10), and CO areas appeared to have worse asthma morbidity...
Are frequent asthma symptoms among low-income individuals related to heavy traffic near homes, vulnerabilities, or both?Ying Ying Meng
UCLA Center for Health Policy Research, Los Angeles, CA 90024, USA
Ann Epidemiol 18:343-50. 2008..To investigate whether frequent asthma symptoms (daily/weekly symptoms) can be attributed to traffic-related exposures, poverty, and/or vulnerabilities...
Glutathione S-transferase mu, omega, pi, and theta class variants and smoking in Parkinson's diseaseAngelika D Wahner
Department of Epidemiology, UCLA School of Public Health, Los Angeles, CA 90095 1772, USA
Neurosci Lett 413:274-8. 2007..54, 95% CI: 0.32-0.90). Results were similar when combining all races. These findings and the paucity of similar studies suggest a need for further inquiry into the association between GSTs, smoking, and PD risk...
Environmental public health tracking of childhood asthma using California health interview survey, traffic, and outdoor air pollution dataMichelle Wilhelm
Department of Epidemiology and Center for Occupational and Environmental Health, School of Public Health, University of California, Los Angeles, California, USA
Environ Health Perspect 116:1254-60. 2008..Despite extensive evidence that air pollution affects childhood asthma, state-level and national-level tracking of asthma outcomes in relation to air pollution is limited...
Inflammatory cytokine gene polymorphisms and increased risk of Parkinson diseaseAngelika D Wahner
Department of Epidemiology, UCLA School of Public Health, University of California, Los Angeles, CA 90095 1772, USA
Arch Neurol 64:836-40. 2007....
Nonsteroidal anti-inflammatory drugs may protect against Parkinson diseaseAngelika D Wahner
Department of Epidemiology, UCLA School of Public Health, Box 951772, 650 Charles E Young Drive, Los Angeles, CA 90095 1772, USA
Neurology 69:1836-42. 2007....
Replication of GWAS associations for GAK and MAPT in Parkinson's diseaseShannon L Rhodes
Department of Epidemiology, UCLA School of Public Health, Los Angeles, CA 90095 1772, USA
Ann Hum Genet 75:195-200. 2011..14) did not replicate in our study population. While MAPT has been considered a PD candidate gene and has been observed in association with PD in other GWAS, GAK is a new candidate for investigation in future studies...
Control selection and pesticide exposure assessment via GIS in prostate cancer studiesJennifer C Marusek
University of California Los Angeles, 90095-1772, USA
Am J Prev Med 30:S109-16. 2006..The use of randomly sampled controls from Medicare and residential parcels listings independent of subject response seems to result in the opportunity for relatively unbiased estimates of pesticide exposures...
Clinical characteristics in early Parkinson's disease in a central California population-based studyGail A Kang
Department of Neurology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095-1772, USA
Mov Disord 20:1133-42. 2005....
A randomized controlled trial evaluating the effects of new task chairs on shoulder and neck pain among sewing machine operators: the Los Angeles garment studyDavid M Rempel
Division of Occupational and Environmental Medicine, Department of Medicine, University of California, San Francisco, CA, USA
Spine (Phila Pa 1976) 32:931-8. 2007..This is a 4-month randomized controlled trial to evaluate the effect of chair design on neck/shoulder pain among sewing machine operators...
Estimated effects of disinfection by-products on preterm birth in a population served by a single water utilityChad Lewis
Environmental Science and Engineering Program, Department of Environmental Health Sciences, School of Public Health, University of California, Los Angeles, California, USA
Environ Health Perspect 115:290-5. 2007..We evaluated the association between drinking-water disinfection by-products and preterm births using improved exposure assessment and more appropriate analysis methods than used in prior studies...
Well-water consumption and Parkinson's disease in rural CaliforniaNicole M Gatto
Department of Epidemiology, University of California Los Angeles, Los Angeles, California 90095 1772, USA
Environ Health Perspect 117:1912-8. 2009..Investigators have hypothesized that consuming pesticide-contaminated well water plays a role in Parkinson's disease (PD), and several previous epidemiologic studies support this hypothesis...
Genetics of iron regulation and the possible role of iron in Parkinson's diseaseShannon L Rhodes
Medical Genetics Institute, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
Neurobiol Dis 32:183-95. 2008....
Research Grants
- Registry Study of Parkinson's Disease in DenmarkBeate Ritz; Fiscal Year: 2009..The proposed research cannot be performed in the US due to a lack of population PD registries that would provide access to such a large number of cases and valid methods for control recruitment from the general population. ..
- Registry Study of Parkinson's Disease in DenmarkBeate Ritz; Fiscal Year: 2007..The proposed research cannot be performed in the US due to a lack of population PD registries that would provide access to such a large number of cases and valid methods for control recruitment from the general population. ..
- Air Pollution and Adverse Birth OutcomesBeate Ritz; Fiscal Year: 2004..abstract_text> ..
- Ergonomic Interventions for Garment WorkBeate Ritz; Fiscal Year: 2004..This study will provide employers, employees and public agencies with evidence of the effectiveness of ergonomic interventions in order to guide health and safety policy. ..
- PARKINSON'S DISEASES SUSCEPTIBILITY GENES AND PESTICIDESBeate Ritz; Fiscal Year: 2004..abstract_text> ..
- Registry Study of Parkinsons Disease in DenmarkBeate R Ritz; Fiscal Year: 2010..The proposed research cannot be performed in the US due to a lack of population PD registries that would provide access to such a large number of cases and valid methods for control recruitment from the general population. ..
