Research Topics
Genomes and Genes
Species | Laure RittieSummaryAffiliation: University of Michigan Country: USA Publications
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Detail Information
Publications
Eccrine sweat glands are major contributors to reepithelialization of human woundsLaure Rittie
Department of Dermatology, University of Michigan, Ann Arbor, Michigan 48109, USA
Am J Pathol 182:163-71. 2013..This novel appreciation of the unique importance of eccrine sweat glands for epidermal repair may be exploited to improve our approaches to understanding and treating human wounds...
Capturing the finer points of gene expression in psoriasis: beaming in on the CCL19/CCR7 axisLaure Rittie
Department of Dermatology, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA
J Invest Dermatol 132:1535-8. 2012..They identify the T-cell activation regulators C-C chemokine ligand 19 and C-C chemokine receptor 7 as potential mediators of immune organization in psoriasis...- Enzymes used in molecular biology: a useful guideLaure Rittie
Department of Dermatology, University of Michigan, Ann Arbor, MI, USA
J Cell Commun Signal 2:25-45. 2008..By pointing out key requirements for each enzymatic activity and clarifying their limitations, we aim at guiding the reader in selecting appropriate enzymatic source and optimal experimental conditions for molecular cloning experiments... - Spatial-temporal modulation of CCN proteins during wound healing in human skin in vivoLaure Rittie
Department of Dermatology, University of Michigan, Medical Science Building I, Rm 6447, 1301 E Catherine, Ann Arbor, MI, 48109, USA
J Cell Commun Signal 5:69-80. 2011.... 
Hedgehog signaling maintains hair follicle stem cell phenotype in young and aged human skinLaure Rittie
Department of Dermatology, University of Michigan, Ann Arbor, MI, USA
Aging Cell 8:738-51. 2009..Together with previously reported knock-out mouse results, these data suggest a role for Hh signaling in maintaining bulge cell phenotype in young and aged human skin...- Amphiregulin carboxy-terminal domain is required for autocrine keratinocyte growthStefan W Stoll
Department of Dermatology, University of Michigan, Ann Arbor, Michigan 48109, USA
J Invest Dermatol 130:2031-40. 2010.... - Metalloproteinase-mediated, context-dependent function of amphiregulin and HB-EGF in human keratinocytes and skinStefan W Stoll
Department of Dermatology, University of Michigan Medical School, Ann Arbor, MI, USA
J Invest Dermatol 130:295-304. 2010..These data show that distinct EGFR ligands stimulate KC behavior in different cellular contexts, and in an MP-dependent fashion... - Differential ErbB1 signaling in squamous cell versus basal cell carcinoma of the skinLaure Rittie
Department of Dermatology, University of Michigan Medical Center, 1500 East Medical Center Drive, Ann Arbor, MI 48109 0932, USA
Am J Pathol 170:2089-99. 2007..Our results suggest that targeting ErbB1 signaling might be of benefit in the treatment of SCC... - Heparin-binding EGF-like growth factor promotes epithelial-mesenchymal transition in human keratinocytesStefan W Stoll
Department of Dermatology, University of Michigan Medical Center, Ann Arbor, Michigan 48109 5675, USA
J Invest Dermatol 132:2148-57. 2012.... - Intraepidermal erbium:YAG laser resurfacing: impact on the dermal matrixJeffrey S Orringer
Department of Dermatology, University of Michigan Medical School, Ann Arbor, Michigan 48109 0314, USA
J Am Acad Dermatol 64:119-28. 2011..Various minimally invasive treatments enhance the skin's appearance. Little is known about the molecular mechanisms whereby treatments working at the epidermal level might alter the dermis... - Molecular analysis of aggressive microdermabrasion in photoaged skinDarius J Karimipour
Department of Dermatology, University of Michigan, 1500 E Medical Center Dr, 1910 Taubman Center, Ann Arbor, MI 48109, USA
Arch Dermatol 145:1114-22. 2009..To investigate dermal remodeling effects of crystal-free microdermabrasion on photodamaged skin... - Enhancing structural support of the dermal microenvironment activates fibroblasts, endothelial cells, and keratinocytes in aged human skin in vivoTaihao Quan
Department of Dermatology, University of Michigan, Ann Arbor, Michigan 48109 5609, USA
J Invest Dermatol 133:658-67. 2013..Thus, fibroblasts in aged human skin retain their capacity for functional activation, which is restored by enhancing structural support of the ECM... - Isolation and culture of skin fibroblastsLaure Rittie
Department of Dermatology, University of Michigan, Ann Arbor, MI, USA
Methods Mol Med 117:83-98. 2005..In this chapter, we describe detailed procedures for establishing and maintaining primary cultures of adult human fibroblasts. We also provide protocols for constructing three-dimensional dermal and skin equivalent culture models... - UV-light-induced signal cascades and skin agingLaure Rittie
Department of Dermatology, University of Michigan, 1150 West Medical Center Drive, R6447 Medical Science I, Ann Arbor, MI 48109 0609, USA
Ageing Res Rev 1:705-20. 2002.... - Induction of collagen by estradiol: difference between sun-protected and photodamaged human skin in vivoLaure Rittie
Department of Dermatology, University of Michigan Medical School, Ann Arbor, MI 48109 0609, USA
Arch Dermatol 144:1129-40. 2008..To evaluate the effectiveness of topical estradiol in stimulating collagen I and III production in naturally aged and photoaged human skin of postmenopausal women and age-matched men... - Decreased collagen production in chronologically aged skin: roles of age-dependent alteration in fibroblast function and defective mechanical stimulationJames Varani
Department of Pathology, The University of Michigan, 1301 Catherine Rd Box 0602, Ann Arbor, MI 48109 USA
Am J Pathol 168:1861-8. 2006..Based on the findings presented here, we conclude that reduced collagen synthesis in chronologically aged skin reflects at least two different underlying mechanisms: cellular fibroblast aging and a lower level of mechanical stimulation... - Retinoid-induced epidermal hyperplasia is mediated by epidermal growth factor receptor activation via specific induction of its ligands heparin-binding EGF and amphiregulin in human skin in vivoLaure Rittie
Department of Dermatology, University of Michigan Medical School, University of Michigan, Ann Arbor, Michigan 48109 0609, USA
J Invest Dermatol 126:732-9. 2006..These data demonstrate the central role of EGFR activation in retinoid-induced epidermal hyperplasia, and suggest that EGFR inhibitors can mitigate retinoid-induced scaling...