Research Topics
Genomes and GenesSpecies | Jon C RittenbergerSummaryAffiliation: University of Pittsburgh Country: USA Publications
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Publications
Errors of omission in the treatment of prehospital chest pain patientsJon C Rittenberger
University of Pittsburgh Affiliated Residency in Emergency Medicine and the Department of Emergency Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
Prehosp Emerg Care 9:2-7. 2005..They also sought to quantify any time delays in treatment of potential ischemic cardiac chest pain...
Successful outcome utilizing hypothermia after cardiac arrest in pregnancy: a case reportJon C Rittenberger
University of Pittsburgh Department of Emergency Medicine, Pittsburgh, PA, USA
Crit Care Med 36:1354-6. 2008..To date, pregnancy has been considered a contraindication to the use of therapeutic hypothermia after cardiac arrest...
Increasing CPR duration prior to first defibrillation does not improve return of spontaneous circulation or survival in a swine model of prolonged ventricular fibrillationJon C Rittenberger
University of Pittsburgh, Department of Emergency Medicine, Pittsburgh, PA 15213, USA
Resuscitation 79:155-60. 2008..In this porcine model of basic life support, our outcomes were rates of return of spontaneous circulation (ROSC), survival, and coronary perfusion pressure (CPP)...
Outcomes of a hospital-wide plan to improve care of comatose survivors of cardiac arrestJon C Rittenberger
Department of Emergency Medicine, University of Pittsburgh, United States
Resuscitation 79:198-204. 2008..We implemented a series of process interventions designed to increase TH use and improve outcomes in patients successfully resuscitated from out-of-hospital cardiac arrest (OHCA) or in-hospital cardiac arrest (IHCA)...
Association of delay to first intervention with return of spontaneous circulation in a swine model of cardiac arrestJon C Rittenberger
University of Pittsburgh, Department of Emergency Medicine, Pittsburgh, PA 15213, USA
Resuscitation 73:154-60. 2007..We sought to determine the duration of circulatory arrest after which maximal drug treatment and a rescue shock would fail to achieve return of spontaneous circulation (ROSC)...
Association between clinical examination and outcome after cardiac arrestJon C Rittenberger
University of Pittsburgh, Department of Emergency Medicine, Pittsburgh, PA 15261, USA
Resuscitation 81:1128-32. 2010..We measured the association between clinical examination findings at hospital arrival, 24, and 72 h after cardiac arrest in a modern intensive care unit setting...
Inter-rater reliability for witnessed collapse and presence of bystander CPRJon C Rittenberger
Department of Emergency Medicine, University of Pittsburgh, 230 McKee Place, Suite 400, Pittsburgh, PA 15213, USA
Resuscitation 70:410-5. 2006..We sought to determine the inter-rater reliability for different methods of ascertaining and defining witnessed collapse and performance of bystander CPR...
Time to give the first medication during resuscitation in out-of-hospital cardiac arrestJon C Rittenberger
Department of Emergency Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA
Resuscitation 70:201-6. 2006..Then, the mean time and ranges of reported study medication delivery in clinical trials where medication was the experimental intervention was determined...
Association between Cerebral Performance Category, Modified Rankin Scale, and discharge disposition after cardiac arrestJon C Rittenberger
University of Pittsburgh, Department of Emergency Medicine, School of Medicine, PA 15261, United States
Resuscitation 82:1036-40. 2011..Cerebral Performance Category (CPC), Modified Rankin Scale (mRS) and discharge disposition are commonly used to determine outcomes following cardiac arrest. This study tested the association between these outcome measures...
Predictors of ROSC in witnessed aeromedical cardiac arrestsJon C Rittenberger
Department of Emergency Medicine, University of Pittsburgh, Pittsburgh, PA, United States
Resuscitation 76:43-6. 2008..We completed a retrospective analysis of aeromedical patient care records in order to describe the pre-arrest characteristics and the return of spontaneous circulation (ROSC) in this subset of patients...
Effects of pre-arrest and intra-arrest hypothermia on ventricular fibrillation and resuscitationJames J Menegazzi
Department of Emergency Medicine, University of Pittsburgh, School of Medicine, Pittsburgh, PA 15213, USA
Resuscitation 80:126-32. 2009..The electrophysiological mechanisms of hypothermia are not well-understood, nor are the effects of beginning cooling during the resuscitation...
The effect of adenosine A1 receptor antagonism on return of spontaneous circulation and short-term survival in prolonged ventricular fibrillationTimothy J Mader
Department of Emergency Medicine, Baystate Medical Center Tufts University School of Medicine, Boston, Massachusetts, USA
Prehosp Emerg Care 12:352-8. 2008..We have previously shown that ADO A1 receptor (ADOA1R) antagonism hastens the time-dependent decay in VF waveform morphology during the circulatory phase of cardiac arrest...
Association between a quantitative CT scan measure of brain edema and outcome after cardiac arrestRobert B Metter
Department of Emergency Medicine, University of Pittsburgh, Pittsburgh, PA, USA
Resuscitation 82:1180-5. 2011..This study tested whether the gray matter attenuation to white matter attenuation ratio (GWR) was associated with survival and functional recovery...
Increased survival after EMS witnessed cardiac arrest. Observations from the Resuscitation Outcomes Consortium (ROC) Epistry-Cardiac arrestDavid Hostler
University of Pittsburgh, Department of Emergency Medicine, Suite 400A, Pittsburgh, PA 15261, USA
Resuscitation 81:826-30. 2010..We examined EMS witnessed OHCA from the Resuscitation Outcomes Consortium (ROC) to determine the effect of EMS witnessed vs. bystander witnessed and unwitnessed OHCA...
An early, novel illness severity score to predict outcome after cardiac arrestJon C Rittenberger
University of Pittsburgh, Department of Emergency Medicine, PA, USA
Resuscitation 82:1399-404. 2011..We developed an early, novel post-arrest illness severity score to predict survival, good outcome and development of multiple organ failure (MOF) after cardiac arrest...
Effects of an impedance threshold device on hemodynamics and restoration of spontaneous circulation in prolonged porcine ventricular fibrillationJames J Menegazzi
Department of Emergency Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
Prehosp Emerg Care 11:179-85. 2007..An impedance threshold device (ITD) has been designed to enhance circulation during CPR by creating a negative intrathoracic pressure during the relaxation phase of chest compression...
Female sex is not associated with improved rates of ROSC or short term survival following prolonged porcine ventricular fibrillationJoshua C Reynolds
Department of Emergency Medicine University of Pittsburgh, Pittsburgh, PA, USA
Resuscitation 83:1386-90. 2012..We hypothesized that sex predicts return of spontaneous circulation (ROSC) and short-term survival (SURV) in porcine studies of prolonged ventricular fibrillation (VF)...
Identification of adverse events in ground transport emergency medical servicesP Daniel Patterson
Department of Emergency Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA
Am J Med Qual 27:139-46. 2012..Overall physician agreement on presence of an AE per chart was fair (κ = 0.24; 95% CI = 0.19, 0.29). These findings should serve as a basis for refining and implementing an AE evaluation instrument...
Drug administration in animal studies of cardiac arrest does not reflect human clinical experienceJoshua C Reynolds
School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, United States
Resuscitation 74:13-26. 2007..Our previous work has shown the mean time to first drug administration in clinical trials is 19.4min. We hypothesized that the average time to drug administration in large animal experiments occurs earlier than in OOHCA clinical trials...
Mild hypothermia alters midazolam pharmacokinetics in normal healthy volunteersDavid Hostler
Department of Emergency Medicine, Emergency Responder Human Performance Laboratory, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
Drug Metab Dispos 38:781-8. 2010..Future studies in patients who receive lower levels and a longer duration of hypothermia are warranted...
Neurological and functional status following cardiac arrest: method and tool utilityKetki D Raina
University of Pittsburgh, School of Health and Rehabilitation Sciences, Department of Occupational Therapy, 5012 Forbes Tower, Pittsburgh, PA 15260, USA
Resuscitation 79:249-56. 2008..This study examined the relationships among the CPC and measures of global disability and QOL at discharge from the hospital and at 1 month after CA...
Frequency and timing of nonconvulsive status epilepticus in comatose post-cardiac arrest subjects treated with hypothermiaJon C Rittenberger
Department of Emergency Medicine, University of Pittsburgh, Pittsburgh, PA 15261, USA
Neurocrit Care 16:114-22. 2012..However, nonconvulsive status epilepticus (NCSE) may cause persistent coma. The frequency and timing of NCSE after cardiac arrest is unknown...
Regional impact of cardiac arrest center criteria on out-of-hospital transportation practicesChristian Martin-Gill
Department of Emergency Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
Prehosp Emerg Care 15:381-7. 2011..We hypothesized that a majority of patients are already transported to hospitals that meet proposed CAC criteria...
Feasibility of basic emergency medical technicians to perform selected advanced life support interventionsFrancis X Guyette
Department of Emergency Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA
Prehosp Emerg Care 10:518-21. 2006..We sought to evaluate the feasibility of training EMT-B providers to provide additional cardiac resuscitation procedures using the laryngeal mask airway (LMA) and intraosseous (IO) access...
Increased chest compression to ventilation ratio improves delivery of CPRDavid Hostler
University of Pittsburgh, Pittsburgh, United States
Resuscitation 74:446-52. 2007..We evaluated a protocol change from the recommended C:V ratio of 15:2-30:2 during CPR in our municipal emergency medical system...
Emergency neurological life support: resuscitation following cardiac arrestJon C Rittenberger
Department of Emergency Medicine, University of Pittsburgh, Pittsburgh, PA, USA
Neurocrit Care 17:S21-8. 2012....
Feasibility of laryngeal mask airway use by prehospital personnel in simulated pediatric respiratory arrestFrancis X Guyette
Department of Emergency Medicine, The University of Pittsburgh, Pittsburgh, PA 15213, USA
Prehosp Emerg Care 11:245-9. 2007..Although the LMA has been used successfully for pediatric resuscitation in the hospital setting, there is no data describing its use in the prehospital setting...
Hypothermia after cardiac arrest does not alter serum inflammatory markersClifton W Callaway
Department of Emergency Medicine, University of Pittsburgh, Pittsburgh, PA, USA
Crit Care Med 36:2607-12. 2008..This study tested whether therapeutic hypothermia altered levels of inflammatory markers in serum...
Work of CPR during two different compression to ventilation ratios with real-time feedbackAmy E Betz
Department of Emergency Medicine, University of Pittsburgh, Pittsburgh, PA 15213, United States
Resuscitation 79:278-82. 2008..The effect of the additional exertion required to deliver more chest compressions may present a considerable physical burden on the provider...
Coronary angiography predicts improved outcome following cardiac arrest: propensity-adjusted analysisJoshua C Reynolds
Department of Emergency Medicine, University of Maryland, Baltimore, Maryland, USA
J Intensive Care Med 24:179-86. 2009..Determine if clinical parameters of resuscitated patients predict coronary angiography (CATH) performance and if receiving CATH after cardiac arrest is associated with outcome...
Receiving hospital characteristics associated with survival after out-of-hospital cardiac arrestClifton W Callaway
Department of Emergency Medicine, University of Pittsburgh, Pittsburgh, PA, USA
Resuscitation 81:524-9. 2010..This study examined whether survival to hospital discharge was related to receiving hospital characteristics, including bed number, capability of performing cardiac catheterization and hospital volume of OOHCA cases...
Effect of crew size on objective measures of resuscitation for out-of-hospital cardiac arrestChristian Martin-Gill
Department of Emergency Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
Prehosp Emerg Care 14:229-34. 2010..Increased numbers of providers may improve the performance of cardiopulmonary resuscitation (CPR), but this has not been studied as part of a comprehensive resuscitation scenario...
Near-infrared spectroscopy in post-cardiac arrest patients undergoing therapeutic hypothermiaBrian Suffoletto
Department of Emergency Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States
Resuscitation 83:986-90. 2012..To investigate the relationship between tissue oxygen saturation during a vascular occlusion test with systemic hemodynamics, central and peripheral skin temperature in patients resuscitated from cardiac arrest...
Comparison of public safety provider injury ratesJoe Suyama
Department of Emergency Medicine, Emergency Responder Human Performance Laboratory, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
Prehosp Emerg Care 13:451-5. 2009..Objective. To determine the types and severity of injuries encountered by public safety personnel during routine work conditions within a single urban population...
In-flight automated external defibrillator use and consultation patternsAaron Michael Brown
University of Pittsburgh Affiliated Residency in Emergency Medicine, Pittsburgh, Pennsylvania 15216, USA
Prehosp Emerg Care 14:235-9. 2010..Limited information exists about the in-flight use and outcomes associated with automated external defibrillators (AEDs) on commercial airlines...
Therapeutic hypothermia after cardiac arrestJessica L Erb
University of Pittsburgh Medical Center Presbyterian Shadyside Hospital, PA, USA
Am J Nurs 112:38-44; quiz 46,45. 2012....
The development and implementation of cardiac arrest centersMichael W Donnino
Department of Emergency Medicine, Beth Israel Deaconess Medical Center, One Deaconess Road, WCC2, Boston, MA 02215, United States
Resuscitation 82:974-8. 2011..This paper may assist other potential clinical sites that are considering or actively developing cardiac arrest centers of their own...
Quality of BLS decreases with increasing resuscitation complexityJon C Rittenberger
University of Pittsburgh Affiliated Residency in Emergency Medicine, Pittsburgh, PA, USA
Resuscitation 68:365-9. 2006..Further decrements might occur when ALS skills enter into resuscitation. These results suggest a need to automate and/or prompt the performance of BLS to optimize resuscitation...
Toxicology laboratory analysis and human exposure to p-chloroanilineAnthony F Pizon
Department of Emergency Medicine, University of Pittsburgh Medical Center, Pennsylvania, USA
Clin Toxicol (Phila) 47:132-6. 2009..An in-vitro study evaluating the metabolism of p-chloroaniline in human hepatocytes was undertaken to evaluate the metabolic fate more closely...
