Research Topics
| Justine M RitchieSummaryAffiliation: University of Iowa Country: USA Publications
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Detail Information
Publications
Organochlorines and risk of prostate cancerJustine M Ritchie
Department of Biostatistics, College of Public Health, University of Iowa, Iowa City, IA 52242, USA
J Occup Environ Med 45:692-702. 2003..This study suggests that long-term, low-dose exposure to specific OCPs and PCBs in the general population may contribute to an increased risk of prostate cancer and supports further investigation in this area...
Does pretreatment seropositivity to human papillomavirus have prognostic significance for head and neck cancers?Elaine M Smith
Department of Epidemiology, College of Public Health, University of Iowa, Iowa City, IA 52242, USA
Cancer Epidemiol Biomarkers Prev 17:2087-96. 2008..Human papillomavirus (HPV) is a risk factor for head and neck cancers (HNC), yet HPV-associated tumors have better prognosis than HPV-negative tumors...- Human papillomavirus in oral exfoliated cells and risk of head and neck cancerElaine M Smith
Department of Epidemiology, College of Public Health, University of Iowa, Iowa City 52242, USA
J Natl Cancer Inst 96:449-55. 2004.... - Comparison of proposed frameworks for grouping polychlorinated biphenyl congener data applied to a case-control pilot study of prostate cancerJustine M Ritchie
Department of Biostatistics, College of Public Health, University of Iowa, Iowa City, IA 52242, USA
Environ Res 98:104-13. 2005..These results suggest that a higher burden of PCBs that are CAR agonists may be positively associated with an increased risk of prostate cancer and they encourage further research in this area... - Human papillomavirus seropositivity and risks of head and neck cancerElaine M Smith
Department of Epidemiology, College of Public Health, University of Iowa, Iowa City, IA 52242, USA
Int J Cancer 120:825-32. 2007..Because of the survival advantage of HPV-related HNC, HPV-16 E6/E7 detection may be useful in therapy targeted for HPV-related tumors... - Prevalence of human papillomavirus in the oral cavity/oropharynx in a large population of children and adolescentsElaine M Smith
Department of Epidemiology, College of Public Health, University of Iowa, Iowa City, IA 52242, USA
Pediatr Infect Dis J 26:836-40. 2007..We evaluated the prevalence of HPV DNA in the oral cavity/oropharynx in a cross section of children aged 2 weeks to 20 years... - Human papillomavirus prevalence and types in newborns and parents: concordance and modes of transmissionElaine M Smith
Department of Epidemiology, College of Public Health, University of Iowa, Iowa City 52242, USA
Sex Transm Dis 31:57-62. 2004..The purpose of this investigation was to determine the risk of vertical and early contact transmission of human papillomavirus (HPV) in newborn infants based on concordance and sequence match to HPV types in parents... - Manganese superoxide dismutase overexpression inhibits the growth of androgen-independent prostate cancer cellsSujatha Venkataraman
Free Radical and Radiation Biology Program -- ESR Facility, University of Iowa, Iowa City, IA 52242-1101, USA
Oncogene 24:77-89. 2005..Therefore, MnSOD not only regulates cell survival but also affects PC-3 cell proliferation by retarding G(1) to S transition. Our results are consistent with MnSOD being a tumor suppressor gene in human prostate cancer... - Age, sexual behavior and human papillomavirus infection in oral cavity and oropharyngeal cancersElaine M Smith
Department of Epidemiology, College of Public Health, University of Iowa, Iowa City, IA 52242, USA
Int J Cancer 108:766-72. 2004..An exfoliated oral cytology test for HPV was a significant predictor of HR types in the cancers, suggesting that an oral rinse may provide an early biomarker of infected tumors... - Alcohol dehydrogenase 3 and risk of squamous cell carcinomas of the head and neckDonghong Wang
Department of Epidemilogy, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA
Cancer Epidemiol Biomarkers Prev 14:626-32. 2005..However, participants with ADH3(1-2) genotype were associated with poorer survival compared with those who had the other two ADH3 genotypes and a higher rate of recurrence than participants with ADH3(1-1) genotype... - Efficacy of beta-lapachone in pancreatic cancer treatment: exploiting the novel, therapeutic target NQO1Matthew Ough
Department of Surgery, University of Iowa College of Medicine, Iowa City, Iowa 52242, USA
Cancer Biol Ther 4:95-102. 2005.... - Metastatic progression of pancreatic cancer: changes in antioxidant enzymes and cell growthAnne Lewis
University of Iowa College of Medicine, Iowa City, 52242, USA
Clin Exp Metastasis 22:523-32. 2005..Metastatic disease is associated with changes in the content and activity of antioxidant enzymes with an associated change in growth characteristics depending on the O(2) concentrations... - Head and neck cancer associated with herpes simplex virus 1 and 2 and other risk factorsTina M Parker
Department of Epidemiology, College of Public Health, University of Iowa, Iowa City, IA 52242, USA
Oral Oncol 42:288-96. 2006..7) or HSV-2 (not estimable). These findings suggest that seropositivity to HSV-1 and HSV-2, although not independent risk factors for HNC, may modify the risk of HNC associated with exposure to tobacco, alcohol, or HPV-HR... - Overexpression of manganese or copper-zinc superoxide dismutase inhibits breast cancer growthChristine J Weydert
Free Radical and Radiation Biology Program, Department of Radiation Oncology, Roy J and Lucille A Carver College of Medicine, The University of Iowa, Iowa City, IA 52242, USA
Free Radic Biol Med 41:226-37. 2006..The first direct comparison of MnSOD to CuZnSOD overexpression indicated that CuZnSOD and MnSOD were similarly effective at suppressing cancer cell growth... - Suppression of the malignant phenotype in human pancreatic cancer cells by the overexpression of manganese superoxide dismutaseChristine Weydert
Department of Radiation Oncology, University of Iowa College of Medicine, Iowa City, Iowa 52242, USA
Mol Cancer Ther 2:361-9. 2003..These results suggest that MnSOD may be a tumor suppressor gene in human pancreatic cancer. Delivery of the MnSOD gene may prove beneficial for suppression of pancreatic cancer growth... - Gonorrhea and chlamydia infection among women visiting family planning clinics: racial variation in prevalence and predictorsLisa A Einwalter
University of Iowa, College of Public Health, Iowa City, IA, USA
Perspect Sex Reprod Health 37:135-40. 2005..Because of the potential impact of these infections on women's reproductive health, it is important to determine whether different factors are predictive of infection in women of different races... - Inhibition of cell growth by overexpression of manganese superoxide dismutase (MnSOD) in human pancreatic carcinomaMatthew Ough
University of Iowa College of Medicine, Iowa City, IA, USA
Free Radic Res 38:1223-33. 2004..These results suggest that MnSOD may be a tumor suppressor gene in human pancreatic cancer... - The pattern of clinical breast cancer metastasis correlates with a single nucleotide polymorphism in the C1qA component of complementEmilian Racila
Holden Comprehensive Cancer Center at the University of Iowa, 5216MERF, University of Iowa, Iowa, IA 52242, USA
Immunogenetics 58:1-8. 2006.... - The relationship of molecular markers of p53 function and angiogenesis to prognosis of stage I epithelial ovarian cancerMichael J Goodheart
Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Iowa Hospital and Clinics, Iowa City, Iowa, USA
Clin Cancer Res 11:3733-42. 2005..Multiple angiogenic factors may influence tumor progression and metastasis. Several are modified by the p53 gene. We sought to identify molecular markers for high-risk stage I epithelial ovarian cancers... - Stress-related mediators stimulate vascular endothelial growth factor secretion by two ovarian cancer cell linesSusan K Lutgendorf
Department of Psychology, University of Iowa, Iowa City, Iowa 52242, USA
Clin Cancer Res 9:4514-21. 2003..The goal of this study was to examine possible mechanisms underlying these relationships... - Physician specialty is significantly associated with hormone replacement therapy useBarcey T Levy
Department of Family Medicine, College of Medicine, University of Iowa, Iowa City, Iowa 52242, USA
Obstet Gynecol 101:114-22. 2003..To compare the characteristics of postmenopausal women seen by gynecologists versus family physicians and to determine factors associated with current hormone replacement therapy (HRT) use... - Human papillomavirus infection as a prognostic factor in carcinomas of the oral cavity and oropharynxJustine M Ritchie
Department of Biostatistics, College of Public Health, University of Iowa, Iowa City, IA 52242, USA
Int J Cancer 104:336-44. 2003..HPV status was identified as an independent prognostic factor in oral and oropharyngeal cancers. This result appeared to be gender-specific, suggesting the need for further study of the interaction between HPV and gender on survival... - Response assessment of aggressive non-Hodgkin's lymphoma by integrated International Workshop Criteria and fluorine-18-fluorodeoxyglucose positron emission tomographyMalik E Juweid
Department of Radiology, Holden Comprehensive Cancer Center, University of Iowa, Iowa City, IA 52242, USA
J Clin Oncol 23:4652-61. 2005.... - Treatment of pancreatic cancer cells with dicumarol induces cytotoxicity and oxidative stressAnne Lewis
Department of Surgery, Radiation Oncology and Holden Comprehensive Cancer Center, and University of Iowa College of Medicine, Iowa City, Iowa, USA
Clin Cancer Res 10:4550-8. 2004..CONCLUSIONS: Inhibition of NQO(1) with dicumarol induces cell killing and oxidative stress in pancreatic cancer cells and speculate that dicumarol may prove to be useful in pancreatic cancer therapeutics... - Preoperative serum vascular endothelial growth factor levels: significance in ovarian cancerBrian C Cooper
Division of Gynecologic Oncology, Departments of Obstetrics and Gynecology, Holden Comprehensive Cancer Center, University of Iowa Hospitals and Clinics, Iowa City, Iowa 52242, USA
Clin Cancer Res 8:3193-7. 2002..004) were significant. CONCLUSIONS: Preoperative VEGF levels may be useful in differentiating benign adnexal masses from malignancy. Preoperative VEGF levels >380 pg/ml are an independent risk factor for death because of disease... - Prevalence and persistence of human papillomavirus in postmenopausal age womenElaine M Smith
Department of Epidemiology, College of Public Health, University of Iowa, 200 Hawkins Drive, C21P GH, Iowa City, IA 52242, USA
Cancer Detect Prev 27:472-80. 2003..1-3.1). These findings suggest that a significant percentage of older women are infected with HPV. This may put them at increased risk of genital cancers with longer use of HRTs. Additional studies are needed... - Inhibition of oral cancer cell growth by adenovirusMnSOD plus BCNU treatmentChristine J Darby Weydert
Free Radical and Radiation Biology Program, Department of Radiation Oncology, Roy J. and Lucille A. Carver College of Medicine and Holden Comprehensive Cancer Center, The University of Iowa, Iowa City, IA 52242, USA
Free Radic Biol Med 34:316-29. 2003..Tumor volume could be decreased further by giving multiple doses of AdMnSOD or inhibiting catalase activity with AT. These results suggest that, by using these combination therapies, a significant decrease in tumor mass can be achieved... - Neutropenia and febrile neutropenia in patients with Hodgkin's lymphoma treated with doxorubicin (Adriamycin), bleomycin, vinblastine and dacarbazine (ABVD) chemotherapyVikram K Chand
Department of Internal Medicine, University of Iowa, IA 52242, USA
Leuk Lymphoma 47:657-63. 2006..It may be possible to maintain dose intensity in the face of uncomplicated neutropenia during ABVD therapy... - Overexpression of manganese superoxide dismutase promotes the survival of prostate cancer cells exposed to hyperthermiaSujatha Venkataraman
Department of Radiation Oncology, Free Radical and Radiation Biology Program, EMRB 68, The University of Iowa, Iowa City, IA 52242 1101, USA
Free Radic Res 38:1119-32. 2004.... 
Case-control study of vulvar vestibulitis risk associated with genital infectionsElaine M Smith
Department of Epidemiology, College of Public Health, University of Iowa, Iowa City, IA 52242, USA
Infect Dis Obstet Gynecol 10:193-202. 2002..To evaluate the risk of vulvar vestibulitis syndrome (VVS) associated with genital infections in a case-control study...- Redox regulation of pancreatic cancer cell growth: role of glutathione peroxidase in the suppression of the malignant phenotypeJingru Liu
Department of Radiation Oncology, University of Iowa College of Medicine, Iowa City, IA 52242, USA
Hum Gene Ther 15:239-50. 2004..GPx may be a tumor suppressor gene in pancreatic cancer. Delivery of the GPx gene alone or in combination with the MnSOD gene may prove beneficial for treatment of pancreatic cancer... - Local control of parameningeal rhabdomyosarcoma: outcomes in non-complete responders to chemoradiationArnold C Paulino
Department of Radiation Oncology, University of Iowa College of Medicine, Iowa City, Iowa, USA
Med Pediatr Oncol 41:118-22. 2003..To determine whether there is a role for surgery in Group III and IV patients with residual parameningeal rhabdomyosarcoma (PM-RMS) after radiotherapy (RT)... - Preoperative CA 125 levels: an independent prognostic factor for epithelial ovarian cancerBrian C Cooper
Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, The University of Iowa Hospitals and Clinics, Iowa City 52242, USA
Obstet Gynecol 100:59-64. 2002..CONCLUSION:Preoperative CA 125 is an independent risk factor for death due to disease in ovarian cancer, but not a reliable predictor of optimal cytoreduction...