Robert A Rissman

Summary

Affiliation: University of California
Country: USA

Publications

  1. doi request reprint Longitudinal plasma amyloid beta as a biomarker of Alzheimer's disease
    Robert A Rissman
    Alzheimer s Disease Cooperative Study, Department of Neurosciences, UCSD School of Medicine, La Jolla, CA 92037 0624, USA
    J Neural Transm 119:843-50. 2012
  2. pmc Corticotropin-releasing factor receptor-dependent effects of repeated stress on tau phosphorylation, solubility, and aggregation
    Robert A Rissman
    Department of Neurosciences, University of California at San Diego, La Jolla, CA 92093 0624, USA
    Proc Natl Acad Sci U S A 109:6277-82. 2012
  3. pmc Stress-induced tau phosphorylation: functional neuroplasticity or neuronal vulnerability?
    Robert A Rissman
    Department of Neurosciences, University of California, San Diego, La Jolla, CA 92037 0624, USA
    J Alzheimers Dis 18:453-7. 2009
  4. pmc Implications for treatment: GABAA receptors in aging, Down syndrome and Alzheimer's disease
    Robert A Rissman
    Department of Neurosciences, University of California, San Diego, La Jolla, California 92093 0624, USA
    J Neurochem 117:613-22. 2011
  5. pmc Lipopolysaccharide-induced tau phosphorylation and kinase activity--modulation, but not mediation, by corticotropin-releasing factor receptors
    Allyson D Roe
    Department of Neurosciences, University of California, San Diego School of Medicine, La Jolla, CA, USA
    Eur J Neurosci 34:448-56. 2011
  6. ncbi request reprint Corticotropin-releasing factor receptors differentially regulate stress-induced tau phosphorylation
    Robert A Rissman
    Laboratory of Neuronal Structure and Function, The Salk Institute for Biological Studies and Foundation for Medical Research, La Jolla, California 92037, USA
    J Neurosci 27:6552-62. 2007
  7. ncbi request reprint The role of caspase cleavage of tau in Alzheimer disease neuropathology
    Carl W Cotman
    Institute for Brain Aging and Dementia, University of California, Irvine, 92697, USA
    J Neuropathol Exp Neurol 64:104-12. 2005
  8. doi request reprint Cortical and subcortical cerebrovascular resistance index in mild cognitive impairment and Alzheimer's disease
    Daniel A Nation
    Veterans Affairs San Diego Healthcare System, San Diego, CA 92161, USA
    J Alzheimers Dis 36:689-98. 2013
  9. pmc Detection and quantification of 8-hydroxy-2'-deoxyguanosine in Alzheimer's transgenic mouse urine using capillary electrophoresis
    Cheng Zhang
    Department of Neurosciences, UCSD School of Medicine, La Jolla, CA 92093, USA
    Electrophoresis 34:2268-74. 2013
  10. doi request reprint Interaction of age and APOE genotype on cerebral blood flow at rest
    Christina E Wierenga
    Research Service, Veterans Affairs San Diego Healthcare System, San Diego, CA, USA
    J Alzheimers Dis 34:921-35. 2013

Detail Information

Publications12

  1. doi request reprint Longitudinal plasma amyloid beta as a biomarker of Alzheimer's disease
    Robert A Rissman
    Alzheimer s Disease Cooperative Study, Department of Neurosciences, UCSD School of Medicine, La Jolla, CA 92037 0624, USA
    J Neural Transm 119:843-50. 2012
    ..In this review, we discuss recent data on plasma β-amyloid (Aβ) and examine the issues that have arisen in establishing it as a reliable biomarker of AD...
  2. pmc Corticotropin-releasing factor receptor-dependent effects of repeated stress on tau phosphorylation, solubility, and aggregation
    Robert A Rissman
    Department of Neurosciences, University of California at San Diego, La Jolla, CA 92093 0624, USA
    Proc Natl Acad Sci U S A 109:6277-82. 2012
    ....
  3. pmc Stress-induced tau phosphorylation: functional neuroplasticity or neuronal vulnerability?
    Robert A Rissman
    Department of Neurosciences, University of California, San Diego, La Jolla, CA 92037 0624, USA
    J Alzheimers Dis 18:453-7. 2009
    ..In this review, the question of whether stress-induced tau-P can be used as a model for examining the relationship between functional neuroplasticity and neuronal vulnerability will be discussed...
  4. pmc Implications for treatment: GABAA receptors in aging, Down syndrome and Alzheimer's disease
    Robert A Rissman
    Department of Neurosciences, University of California, San Diego, La Jolla, California 92093 0624, USA
    J Neurochem 117:613-22. 2011
    ..When developing AD therapeutics that modulate GABA it is important to consider how E/I balance impacts AD pathogenesis and the relationship between seizure activity and cognitive decline...
  5. pmc Lipopolysaccharide-induced tau phosphorylation and kinase activity--modulation, but not mediation, by corticotropin-releasing factor receptors
    Allyson D Roe
    Department of Neurosciences, University of California, San Diego School of Medicine, La Jolla, CA, USA
    Eur J Neurosci 34:448-56. 2011
    ..CRFR mediation of stress-induced hippocampal tau-P may be limited to emotional stressors...
  6. ncbi request reprint Corticotropin-releasing factor receptors differentially regulate stress-induced tau phosphorylation
    Robert A Rissman
    Laboratory of Neuronal Structure and Function, The Salk Institute for Biological Studies and Foundation for Medical Research, La Jolla, California 92037, USA
    J Neurosci 27:6552-62. 2007
    ....
  7. ncbi request reprint The role of caspase cleavage of tau in Alzheimer disease neuropathology
    Carl W Cotman
    Institute for Brain Aging and Dementia, University of California, Irvine, 92697, USA
    J Neuropathol Exp Neurol 64:104-12. 2005
    ..In addition, a model is presented whereby caspase cleavage of tau provides a mechanistic link between the development of amyloid and tangle pathologies...
  8. doi request reprint Cortical and subcortical cerebrovascular resistance index in mild cognitive impairment and Alzheimer's disease
    Daniel A Nation
    Veterans Affairs San Diego Healthcare System, San Diego, CA 92161, USA
    J Alzheimers Dis 36:689-98. 2013
    ..OBJECTIVe: To compare probable AD patients to mild cognitive impairment (MCI) and normal control (NC) participants on CVRi, the ratio of mean arterial pressure to rCBF...
  9. pmc Detection and quantification of 8-hydroxy-2'-deoxyguanosine in Alzheimer's transgenic mouse urine using capillary electrophoresis
    Cheng Zhang
    Department of Neurosciences, UCSD School of Medicine, La Jolla, CA 92093, USA
    Electrophoresis 34:2268-74. 2013
    ..Collectively, our results indicate that this methodology offers great advantages, such as high separation efficiency, good selectivity, low limit of detection, simplicity and low cost of analysis. ..
  10. doi request reprint Interaction of age and APOE genotype on cerebral blood flow at rest
    Christina E Wierenga
    Research Service, Veterans Affairs San Diego Healthcare System, San Diego, CA, USA
    J Alzheimers Dis 34:921-35. 2013
    ..Findings may partially support suggestions that the gene exerts antagonistic pleiotropic effects...
  11. ncbi request reprint GABA(A) receptors in aging and Alzheimer's disease
    Robert A Rissman
    Laboratory of Neuronal Structure and Function, The Salk Institute for Biological Studies, La Jolla, California, USA
    J Neurochem 103:1285-92. 2007
    ..It is therefore crucial to understand the subunit composition of individual GABA(A) receptors in the diseased brain when developing therapeutics that act at these receptors...
  12. pmc Caspase-cleavage of tau is an early event in Alzheimer disease tangle pathology
    Robert A Rissman
    Institute for Brain Aging and Dementia, University of California, Irvine 92697, USA
    J Clin Invest 114:121-30. 2004
    ..These results suggest that therapeutics aimed at inhibiting tau caspase-cleavage may prove beneficial not only in preventing NFT formation, but also in slowing cognitive decline...