April L Risinger

Summary

Affiliation: University of Texas Health Science Center
Country: USA

Publications

  1. ncbi The taccalonolides, novel microtubule stabilizers, and γ-radiation have additive effects on cellular viability
    April L Risinger
    Department of Pharmacology, University of Texas Health Science Center at San Antonio, TX, United States
    Cancer Lett 307:104-11. 2011
  2. ncbi Potent taccalonolides, AF and AJ, inform significant structure-activity relationships and tubulin as the binding site of these microtubule stabilizers
    Jing Li
    Department of Pharmacology, University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229, USA
    J Am Chem Soc 133:19064-7. 2011
  3. ncbi Cellular studies reveal mechanistic differences between taccalonolide A and paclitaxel
    April L Risinger
    Department of Pharmacology, University of Texas Health Science Center, San Antonio, TX, USA
    Cell Cycle 10:2162-71. 2011
  4. ncbi Identification and biological activities of new taccalonolide microtubule stabilizers
    Jiangnan Peng
    Department of Pharmacology, University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229, USA
    J Med Chem 54:6117-24. 2011
  5. ncbi Taccalonolides: Novel microtubule stabilizers with clinical potential
    April L Risinger
    Department of Pharmacology, The University of Texas Health Science Center at San Antonio, 78229, United States
    Cancer Lett 291:14-9. 2010

Detail Information

Publications5

  1. ncbi The taccalonolides, novel microtubule stabilizers, and γ-radiation have additive effects on cellular viability
    April L Risinger
    Department of Pharmacology, University of Texas Health Science Center at San Antonio, TX, United States
    Cancer Lett 307:104-11. 2011
    ..These studies suggest that diverse antimitotic agents, including the taccalonolides, may have utility in chemoradiotherapy...
  2. ncbi Potent taccalonolides, AF and AJ, inform significant structure-activity relationships and tubulin as the binding site of these microtubule stabilizers
    Jing Li
    Department of Pharmacology, University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229, USA
    J Am Chem Soc 133:19064-7. 2011
    ..The potencies of taccalonolides AF and AJ and their direct interaction with tubulin, together with the previous excellent in vivo antitumor activity of this class, reveal the potential of the taccalonolides as new anticancer agents...
  3. ncbi Cellular studies reveal mechanistic differences between taccalonolide A and paclitaxel
    April L Risinger
    Department of Pharmacology, University of Texas Health Science Center, San Antonio, TX, USA
    Cell Cycle 10:2162-71. 2011
    ....
  4. ncbi Identification and biological activities of new taccalonolide microtubule stabilizers
    Jiangnan Peng
    Department of Pharmacology, University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229, USA
    J Med Chem 54:6117-24. 2011
    ..In vivo antitumor evaluations of taccalonolides A, E, and N show that each of these molecules has in vivo antitumor activity...
  5. ncbi Taccalonolides: Novel microtubule stabilizers with clinical potential
    April L Risinger
    Department of Pharmacology, The University of Texas Health Science Center at San Antonio, 78229, United States
    Cancer Lett 291:14-9. 2010
    ..We also discuss the challenges in formulation and supply that will need to be solved before the taccalonolides can become candidates for clinical development...