LINDA M RINAMAN

Summary

Affiliation: University of Pittsburgh
Country: USA

Publications

  1. ncbi request reprint GLP-1 receptor signaling contributes to anorexigenic effect of centrally administered oxytocin in rats
    Linda Rinaman
    Department of Neuroscience, University of Pittsburgh, 446 Crawford Hall, Pittsburgh, PA 15260, USA
    Am J Physiol Regul Integr Comp Physiol 283:R99-106. 2002
  2. pmc Hindbrain noradrenergic A2 neurons: diverse roles in autonomic, endocrine, cognitive, and behavioral functions
    Linda Rinaman
    Dept of Neuroscience, University of Pittsburgh, A210 Langley Hall, Pittsburgh, PA 15260, USA
    Am J Physiol Regul Integr Comp Physiol 300:R222-35. 2011
  3. pmc Ascending projections from the caudal visceral nucleus of the solitary tract to brain regions involved in food intake and energy expenditure
    Linda Rinaman
    Department of Neuroscience, University of Pittsburgh, Pittsburgh, PA 15260, USA
    Brain Res 1350:18-34. 2010
  4. pmc Ondansetron blocks LiCl-induced conditioned place avoidance but not conditioned taste/flavor avoidance in rats
    Linda Rinaman
    Department of Neuroscience, University of Pittsburgh, Pittsburgh, PA 15260, USA
    Physiol Behav 98:381-5. 2009
  5. ncbi request reprint Experimental dissociation of neural circuits underlying conditioned avoidance and hypophagic responses to lithium chloride
    Linda Rinaman
    Department of Neuroscience, Univ of Pittsburgh, A210 Langley Hall, Pittsburgh, PA 15260, USA
    Am J Physiol Regul Integr Comp Physiol 293:R1495-503. 2007
  6. pmc Visceral sensory inputs to the endocrine hypothalamus
    Linda Rinaman
    Department of Neuroscience, University of Pittsburgh, Pittsburgh, PA 15260, USA
    Front Neuroendocrinol 28:50-60. 2007
  7. ncbi request reprint Ontogeny of hypothalamic-hindbrain feeding control circuits
    Linda Rinaman
    Department of Neuroscience, 446 Crawford Hall, University of Pittsburgh, PA 15260, USA
    Dev Psychobiol 48:389-96. 2006
  8. pmc Early life experience shapes the functional organization of stress-responsive visceral circuits
    Linda Rinaman
    Department of Neuroscience, University of Pittsburgh, Pittsburgh, PA, USA
    Physiol Behav 104:632-40. 2011
  9. ncbi request reprint Dehydration anorexia is attenuated in oxytocin-deficient mice
    Linda Rinaman
    University of Pittsburgh, Department of Neuroscience, 446 Crawford Hall, Pittsburgh, PA 15260, USA
    Am J Physiol Regul Integr Comp Physiol 288:R1791-9. 2005
  10. ncbi request reprint Anterograde transneuronal viral tracing of central viscerosensory pathways in rats
    Linda Rinaman
    Department of Neuroscience, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA
    J Neurosci 24:2782-6. 2004

Research Grants

Collaborators

Detail Information

Publications22

  1. ncbi request reprint GLP-1 receptor signaling contributes to anorexigenic effect of centrally administered oxytocin in rats
    Linda Rinaman
    Department of Neuroscience, University of Pittsburgh, 446 Crawford Hall, Pittsburgh, PA 15260, USA
    Am J Physiol Regul Integr Comp Physiol 283:R99-106. 2002
    ..These findings implicate endogenous GLP-1 receptor signaling as an important downstream mediator of anorexia in rats after activation of central OT neural pathways...
  2. pmc Hindbrain noradrenergic A2 neurons: diverse roles in autonomic, endocrine, cognitive, and behavioral functions
    Linda Rinaman
    Dept of Neuroscience, University of Pittsburgh, A210 Langley Hall, Pittsburgh, PA 15260, USA
    Am J Physiol Regul Integr Comp Physiol 300:R222-35. 2011
    ....
  3. pmc Ascending projections from the caudal visceral nucleus of the solitary tract to brain regions involved in food intake and energy expenditure
    Linda Rinaman
    Department of Neuroscience, University of Pittsburgh, Pittsburgh, PA 15260, USA
    Brain Res 1350:18-34. 2010
    ..e., hypophagic) responses to stress...
  4. pmc Ondansetron blocks LiCl-induced conditioned place avoidance but not conditioned taste/flavor avoidance in rats
    Linda Rinaman
    Department of Neuroscience, University of Pittsburgh, Pittsburgh, PA 15260, USA
    Physiol Behav 98:381-5. 2009
    ..These results support the view that CPA is an additional useful tool to reveal the experience of malaise and nausea in rats, whereas CT/FA demonstrated in bottle intake tests is insufficient for this purpose...
  5. ncbi request reprint Experimental dissociation of neural circuits underlying conditioned avoidance and hypophagic responses to lithium chloride
    Linda Rinaman
    Department of Neuroscience, Univ of Pittsburgh, A210 Langley Hall, Pittsburgh, PA 15260, USA
    Am J Physiol Regul Integr Comp Physiol 293:R1495-503. 2007
    ..These findings support the view that distinct central nervous system circuits underlie LiCl-induced inhibition of food intake and conditioned avoidance behavior in rats...
  6. pmc Visceral sensory inputs to the endocrine hypothalamus
    Linda Rinaman
    Department of Neuroscience, University of Pittsburgh, Pittsburgh, PA 15260, USA
    Front Neuroendocrinol 28:50-60. 2007
    ..The postnatal development of these ascending pathways also is considered...
  7. ncbi request reprint Ontogeny of hypothalamic-hindbrain feeding control circuits
    Linda Rinaman
    Department of Neuroscience, 446 Crawford Hall, University of Pittsburgh, PA 15260, USA
    Dev Psychobiol 48:389-96. 2006
    ..Thus, the postnatal emergence of new feeding controls may reflect the emerging access of these controls to DVC neural circuits...
  8. pmc Early life experience shapes the functional organization of stress-responsive visceral circuits
    Linda Rinaman
    Department of Neuroscience, University of Pittsburgh, Pittsburgh, PA, USA
    Physiol Behav 104:632-40. 2011
    ..Early life experience may contribute to meaningful individual differences in emotionality and stress responsiveness by shaping the postnatal developmental trajectory of central visceral circuits...
  9. ncbi request reprint Dehydration anorexia is attenuated in oxytocin-deficient mice
    Linda Rinaman
    University of Pittsburgh, Department of Neuroscience, 446 Crawford Hall, Pittsburgh, PA 15260, USA
    Am J Physiol Regul Integr Comp Physiol 288:R1791-9. 2005
    ..These findings support the view that OT-containing projections from the hypothalamus to the hindbrain are necessary for the full expression of compensatory behavioral and physiological responses to dehydration...
  10. ncbi request reprint Anterograde transneuronal viral tracing of central viscerosensory pathways in rats
    Linda Rinaman
    Department of Neuroscience, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA
    J Neurosci 24:2782-6. 2004
    ..We conclude that transneuronal transport of H129 occurs exclusively in the anterograde direction to reveal CNS regions that receive direct and relayed viscerosensory signals...
  11. ncbi request reprint Postnatal development of hypothalamic inputs to the dorsal vagal complex in rats
    Linda Rinaman
    Department of Neuroscience, University of Pittsburgh, 446 Crawford Hall, Pittsburgh, PA 15260, USA
    Physiol Behav 79:65-70. 2003
    ....
  12. ncbi request reprint Hindbrain noradrenergic lesions attenuate anorexia and alter central cFos expression in rats after gastric viscerosensory stimulation
    Linda Rinaman
    Department of Neuroscience, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA
    J Neurosci 23:10084-92. 2003
    ....
  13. ncbi request reprint The anxiogenic drug yohimbine activates central viscerosensory circuits in rats
    Elizabeth A Myers
    Department of Neuroscience, University of Pittsburgh, PA 15260, USA
    J Comp Neurol 492:426-41. 2005
    ....
  14. ncbi request reprint Trimethylthiazoline supports conditioned flavor avoidance and activates viscerosensory, hypothalamic, and limbic circuits in rats
    Elizabeth A Myers
    Department of Neuroscience, University of Pittsburgh, 446 Crawford Hall, Pittsburgh, PA 15260, USA
    Am J Physiol Regul Integr Comp Physiol 288:R1716-26. 2005
    ..Thus the ability of TMT to support conditioned avoidance behavior is correlated with significant odor-induced recruitment of hypothalamic CRH neurons and brain stem viscerosensory inputs to the CeA...
  15. ncbi request reprint Noradrenergic inputs to the bed nucleus of the stria terminalis and paraventricular nucleus of the hypothalamus underlie hypothalamic-pituitary-adrenal axis but not hypophagic or conditioned avoidance responses to systemic yohimbine
    Layla Banihashemi
    Department of Neuroscience, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA
    J Neurosci 26:11442-53. 2006
    ..Conversely, NA-mediated activation of BNST and PVNmp neurons is unnecessary for YO to inhibit food intake or support CFA, evidence for the sufficiency of other intact neural pathways in mediating those effects...
  16. ncbi request reprint Viscerosensory activation of noradrenergic inputs to the amygdala in rats
    Elizabeth A Myers
    Department of Neuroscience, University of Pittsburgh, 446 Crawford Hall, 15260, Pittsburgh, PA, USA
    Physiol Behav 77:723-9. 2002
    ..These findings suggest that vagal afferent stimulation may modify amygdalar processes of emotional learning via direct noradrenergic/adrenergic projections from the caudal medulla to the CeA...
  17. ncbi request reprint Progressive postnatal increases in Fos immunoreactivity in the forebrain and brain stem of rats after viscerosensory stimulation with lithium chloride
    Thomas J Koehnle
    Department of Neuroscience, University of Pittsburgh, Pittsburgh, PA 15260, USA
    Am J Physiol Regul Integr Comp Physiol 292:R1212-23. 2007
    ..These results indicate that central LiCl-sensitive interoceptive circuits in rats are not fully functional at birth, and show age-dependent increases in neural Fos responses to viscerosensory stimulation with LiCl...
  18. ncbi request reprint Enhanced corticosterone concentrations and attenuated Fos expression in the medial amygdala of female oxytocin knockout mice exposed to psychogenic stress
    Rose C Mantella
    Department of Pharmaceutical Sciences, University of Pittsburgh, 904 Salk Hall, Pittsburgh, PA 15261, USA
    Am J Physiol Regul Integr Comp Physiol 287:R1494-504. 2004
    ..Our findings indicate heightened stress-induced corticosterone release in female OT knockout mice. Therefore, the results suggest that OT pathways play a role in attenuating the HPA axis response to psychogenic stress in female mice...
  19. ncbi request reprint Cholecystokinin and D-fenfluramine inhibit food intake in oxytocin-deficient mice
    Rose C Mantella
    Dept of Pharmaceutical Sciences, Univ of Pittsburgh, 904 Salk Hall, Pittsburgh, PA 15261, USA
    Am J Physiol Regul Integr Comp Physiol 285:R1037-45. 2003
    ..We conclude that OT signaling pathways are unnecessary for the anorexigenic effects of systemically administered CCK and d-fenfluramine in C57BL/6 mice...
  20. pmc A potential gastrointestinal link between enhanced postnatal maternal care and reduced anxiety-like behavior in adolescent rats
    Brittany C Weber
    Department of Neuroscience, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA
    Behav Neurosci 123:1178-84. 2009
    ....
  21. ncbi request reprint Early experience modifies the postnatal assembly of autonomic emotional motor circuits in rats
    J Patrick Card
    Department of Neuroscience, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA
    J Neurosci 25:9102-11. 2005
    ..These findings support the view that environmental events during early postnatal life can influence the formation of neural circuits that provide limbic and cortical control over autonomic emotional motor output...
  22. ncbi request reprint Enhanced initial and sustained intake of sucrose solution in mice with an oxytocin gene deletion
    Janet A Amico
    Department of Medicine, Univ of Pittsburgh, Pittsburgh, PA 15261, USA
    Am J Physiol Regul Integr Comp Physiol 289:R1798-806. 2005
    ..Thus central OT pathways may normally participate in limiting initial intake of novel ingesta and may also participate in limiting intake of sweet, highly palatable familiar ingesta...

Research Grants13

  1. Early Life Experience Shapes Visceral Circuits
    LINDA M RINAMAN; Fiscal Year: 2010
    ....
  2. Central Viscerosensory Circuits-Structure and Function
    Linda Rinaman; Fiscal Year: 2007
    ..abstract_text> ..
  3. Central Viscerosensory Circuits - Structure and Function
    LINDA M RINAMAN; Fiscal Year: 2010
    ..Experimental outcomes could lead to the development of new therapeutic options for treating stress-related emotional pathologies. ..