WILLIAM RICKE

Summary

Affiliation: University of Rochester
Country: USA

Publications

  1. ncbi request reprint Steroid hormones and carcinogenesis of the prostate: the role of estrogens
    William A Ricke
    Department of Urology, James P Wilmot Cancer Center, University of Rochester Medical Center, Rochester, NY 14642, USA
    Differentiation 75:871-82. 2007
  2. ncbi request reprint Prostatic hormonal carcinogenesis is mediated by in situ estrogen production and estrogen receptor alpha signaling
    William A Ricke
    Department of Urology, James P Wilmot Cancer Center, University of Rochester Medical Center, Rochester, New York 14642, USA
    FASEB J 22:1512-20. 2008
  3. pmc Increased prostate cell proliferation and loss of cell differentiation in mice lacking prostate epithelial androgen receptor
    Chun Te Wu
    George Whipple Laboratory for Cancer Research, Departments of Pathology and Urology, University of Rochester, Rochester, NY 14620, USA
    Proc Natl Acad Sci U S A 104:12679-84. 2007
  4. pmc Androgen receptor is a tumor suppressor and proliferator in prostate cancer
    Yuanjie Niu
    George Whipple Lab for Cancer Research, Department of Pathology, University of Rochester Medical Center, Rochester, NY 14620, USA
    Proc Natl Acad Sci U S A 105:12182-7. 2008
  5. ncbi request reprint Steroid hormones stimulate human prostate cancer progression and metastasis
    William A Ricke
    Department of Anatomy, University of California, San Francisco, CA 94143, USA
    Int J Cancer 118:2123-31. 2006
  6. ncbi request reprint Role of the stromal microenvironment in carcinogenesis of the prostate
    Gerald R Cunha
    Department of Anatomy, University of California, San Francisco, CA 94143, USA
    Int J Cancer 107:1-10. 2003
  7. pmc Liquiritigenin is a plant-derived highly selective estrogen receptor beta agonist
    Jennifer E Mersereau
    Department of Obstetrics, Gynecology and Reproductive Sciences and Center for Reproductive Sciences, Cellular and Molecular Pharmacology, University of California, San Francisco, CA, United States
    Mol Cell Endocrinol 283:49-57. 2008

Collaborators

Detail Information

Publications7

  1. ncbi request reprint Steroid hormones and carcinogenesis of the prostate: the role of estrogens
    William A Ricke
    Department of Urology, James P Wilmot Cancer Center, University of Rochester Medical Center, Rochester, NY 14642, USA
    Differentiation 75:871-82. 2007
    ..Answers to these questions will further our understanding of the mechanisms of estrogen/ER signaling and will serve as a basis for chemopreventive and/or chemotherapeutic strategies for prostate cancer...
  2. ncbi request reprint Prostatic hormonal carcinogenesis is mediated by in situ estrogen production and estrogen receptor alpha signaling
    William A Ricke
    Department of Urology, James P Wilmot Cancer Center, University of Rochester Medical Center, Rochester, New York 14642, USA
    FASEB J 22:1512-20. 2008
    ..This mouse model provides a means to examine genetic gain and loss of function and determine the efficacy of therapeutics on prostatic carcinogenesis...
  3. pmc Increased prostate cell proliferation and loss of cell differentiation in mice lacking prostate epithelial androgen receptor
    Chun Te Wu
    George Whipple Laboratory for Cancer Research, Departments of Pathology and Urology, University of Rochester, Rochester, NY 14620, USA
    Proc Natl Acad Sci U S A 104:12679-84. 2007
    ..These data support the hypothesis that epithelial AR controls prostate growth by suppressing epithelial proliferation in the mature gland...
  4. pmc Androgen receptor is a tumor suppressor and proliferator in prostate cancer
    Yuanjie Niu
    George Whipple Lab for Cancer Research, Department of Pathology, University of Rochester Medical Center, Rochester, NY 14620, USA
    Proc Natl Acad Sci U S A 105:12182-7. 2008
    ..Collectively, our understanding of these opposing roles of prostatic AR may revolutionize the way we combat prostate cancer, and allow the development of new and better therapies by targeting only the proliferative role of AR...
  5. ncbi request reprint Steroid hormones stimulate human prostate cancer progression and metastasis
    William A Ricke
    Department of Anatomy, University of California, San Francisco, CA 94143, USA
    Int J Cancer 118:2123-31. 2006
    ..Use of mUGM in this system will allow future studies to utilize the power of mouse genetics to identify paracrine factors involved in human prostatic carcinogenesis...
  6. ncbi request reprint Role of the stromal microenvironment in carcinogenesis of the prostate
    Gerald R Cunha
    Department of Anatomy, University of California, San Francisco, CA 94143, USA
    Int J Cancer 107:1-10. 2003
    ..Thus, the stromal microenvironment is a critical determinant of benign versus malignant growth...
  7. pmc Liquiritigenin is a plant-derived highly selective estrogen receptor beta agonist
    Jennifer E Mersereau
    Department of Obstetrics, Gynecology and Reproductive Sciences and Center for Reproductive Sciences, Cellular and Molecular Pharmacology, University of California, San Francisco, CA, United States
    Mol Cell Endocrinol 283:49-57. 2008
    ..In a mouse xenograph model, liquiritigenin did not stimulate uterine size or tumorigenesis of MCF-7 breast cancer cells. Our results demonstrate that some plants contain highly selective estrogens for ERbeta...

Research Grants4

  1. Stromal androgen receptors mediated human prostate Cancer progression
    WILLIAM RICKE; Fiscal Year: 2007
    ..These experiments will provide key insight into the prevention of human PRCA and lead to a better understanding of the mechanisms of androgen action in human prostate carcinogenesis. ..
  2. Stromal androgen receptors mediated human prostate Cancer progression
    WILLIAM RICKE; Fiscal Year: 2009
    ..These experiments will provide key insight into the prevention of human PRCA and lead to a better understanding of the mechanisms of androgen action in human prostate carcinogenesis. ..