J D Richter

Summary

Affiliation: University of Massachusetts Medical Center
Country: USA

Publications

  1. pmc Cytoplasmic polyadenylation in development and beyond
    J D Richter
    Department of Molecular Genetics and Microbiology, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
    Microbiol Mol Biol Rev 63:446-56. 1999
  2. ncbi request reprint CPEB phosphorylation and cytoplasmic polyadenylation are catalyzed by the kinase IAK1/Eg2 in maturing mouse oocytes
    R Hodgman
    Department of Molecular Genetics and Microbiology, University of Massachusetts Medical School, Worcester, MA 01605, USA
    Development 128:2815-22. 2001
  3. ncbi request reprint Phosphorylation of CPEB by Eg2 mediates the recruitment of CPSF into an active cytoplasmic polyadenylation complex
    R Mendez
    Department of Molecular Genetics and Microbiology University of Massachusetts Medical School, Worcester, MA 01655, USA
    Mol Cell 6:1253-9. 2000
  4. ncbi request reprint CPEB, maskin, and cyclin B1 mRNA at the mitotic apparatus: implications for local translational control of cell division
    I Groisman
    Department of Molecular Genetics and Microbiology, University of Massachusetts Medical School, Worcester 01655, USA
    Cell 103:435-47. 2000
  5. ncbi request reprint Translational control by CPEB: a means to the end
    R Mendez
    Department of Molecular Genetics and Microbiology, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
    Nat Rev Mol Cell Biol 2:521-9. 2001
  6. ncbi request reprint Germ cell differentiation and synaptonemal complex formation are disrupted in CPEB knockout mice
    J Tay
    Department of Molecular Genetics and Microbiology, University of Massachusetts Medical School, Worcester 01655, USA
    Dev Cell 1:201-13. 2001
  7. ncbi request reprint Phosphorylation of CPE binding factor by Eg2 regulates translation of c-mos mRNA
    R Mendez
    Department of Molecular Genetics and Microbiology, University of Massachusetts Medical Center, Worcester 01655, USA
    Nature 404:302-7. 2000
  8. ncbi request reprint Development. The message is in the translation
    J D Richter
    Department of Molecular Genetics and Microbiology, University of Massachusetts Medical School, Worcester, MA 01605, USA
    Science 293:60-2. 2001
  9. pmc The 36-kilodalton embryonic-type cytoplasmic polyadenylation element-binding protein in Xenopus laevis is ElrA, a member of the ELAV family of RNA-binding proteins
    L Wu
    Department of Molecular Genetics and Microbiology, University of Massachusetts Medical Center, Worcester 01655, USA
    Mol Cell Biol 17:6402-9. 1997
  10. pmc Think globally, translate locally: what mitotic spindles and neuronal synapses have in common
    J D Richter
    Department of Molecular Genetics and Microbiology, University of Massachusetts Medical School, Biotech 4, Room 330, 377 Plantation Street, Worcester, MA 01605, USA
    Proc Natl Acad Sci U S A 98:7069-71. 2001

Collaborators

Detail Information

Publications13

  1. pmc Cytoplasmic polyadenylation in development and beyond
    J D Richter
    Department of Molecular Genetics and Microbiology, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
    Microbiol Mol Biol Rev 63:446-56. 1999
    ..Finally, there may be multiple mechanisms by which polyadenylation promotes translation. Important questions yet to be answered in the field of cytoplasmic polyadenylation are addressed...
  2. ncbi request reprint CPEB phosphorylation and cytoplasmic polyadenylation are catalyzed by the kinase IAK1/Eg2 in maturing mouse oocytes
    R Hodgman
    Department of Molecular Genetics and Microbiology, University of Massachusetts Medical School, Worcester, MA 01605, USA
    Development 128:2815-22. 2001
    ..These data indicate that cytoplasmic polyadenylation in mouse oocytes is mediated by IAK1/Eg2-catalyzed phosphorylation of CPEB...
  3. ncbi request reprint Phosphorylation of CPEB by Eg2 mediates the recruitment of CPSF into an active cytoplasmic polyadenylation complex
    R Mendez
    Department of Molecular Genetics and Microbiology University of Massachusetts Medical School, Worcester, MA 01655, USA
    Mol Cell 6:1253-9. 2000
    ..These results demonstrate that the molecular function of Eg2-phosphorylated CPEB is to recruit CPSF into an active cytoplasmic polyadenylation complex...
  4. ncbi request reprint CPEB, maskin, and cyclin B1 mRNA at the mitotic apparatus: implications for local translational control of cell division
    I Groisman
    Department of Molecular Genetics and Microbiology, University of Massachusetts Medical School, Worcester 01655, USA
    Cell 103:435-47. 2000
    ..These data suggest that CPEB-regulated mRNA translation is important for the integrity of the mitotic apparatus and for cell division...
  5. ncbi request reprint Translational control by CPEB: a means to the end
    R Mendez
    Department of Molecular Genetics and Microbiology, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
    Nat Rev Mol Cell Biol 2:521-9. 2001
    ..What are the features and functions of this multifaceted protein?..
  6. ncbi request reprint Germ cell differentiation and synaptonemal complex formation are disrupted in CPEB knockout mice
    J Tay
    Department of Molecular Genetics and Microbiology, University of Massachusetts Medical School, Worcester 01655, USA
    Dev Cell 1:201-13. 2001
    ..Synaptonemal complexes were not detected in these animals. CPEB therefore controls germ cell differentiation by regulating the formation of the synaptonemal complex...
  7. ncbi request reprint Phosphorylation of CPE binding factor by Eg2 regulates translation of c-mos mRNA
    R Mendez
    Department of Molecular Genetics and Microbiology, University of Massachusetts Medical Center, Worcester 01655, USA
    Nature 404:302-7. 2000
    ..In addition, we show that this selective, early phosphorylation of CPEB is catalysed by Eg2, a member of the Aurora family of serine/threonine protein kinases...
  8. ncbi request reprint Development. The message is in the translation
    J D Richter
    Department of Molecular Genetics and Microbiology, University of Massachusetts Medical School, Worcester, MA 01605, USA
    Science 293:60-2. 2001
  9. pmc The 36-kilodalton embryonic-type cytoplasmic polyadenylation element-binding protein in Xenopus laevis is ElrA, a member of the ELAV family of RNA-binding proteins
    L Wu
    Department of Molecular Genetics and Microbiology, University of Massachusetts Medical Center, Worcester 01655, USA
    Mol Cell Biol 17:6402-9. 1997
    ..The possible functions of ElrA in gastrulation are discussed...
  10. pmc Think globally, translate locally: what mitotic spindles and neuronal synapses have in common
    J D Richter
    Department of Molecular Genetics and Microbiology, University of Massachusetts Medical School, Biotech 4, Room 330, 377 Plantation Street, Worcester, MA 01605, USA
    Proc Natl Acad Sci U S A 98:7069-71. 2001
    ..Therefore, CPEB-controlled local translation may influence such seemingly disparate processes as the cell cycle and synaptic plasticity...
  11. ncbi request reprint Maskin is a CPEB-associated factor that transiently interacts with elF-4E
    B Stebbins-Boaz
    Department of Molecular Genetics and Microbiology, University of Massachusetts Medical School, Worcester 01655, USA
    Mol Cell 4:1017-27. 1999
    ..The dissolution of this complex may result in the binding of elF-4E to elF-4G and the translational activation of CPE-containing mRNAs...
  12. ncbi request reprint Translational control in vertebrate development
    C H de Moor
    Department of Molecular Genetics and Microbiology, University of Massachusetts Medical School, Worcester 01655, USA
    Int Rev Cytol 203:567-608. 2001
    ..This review discusses examples of translational control and their relevance for developmental regulation...
  13. ncbi request reprint CPEB-mediated cytoplasmic polyadenylation and the regulation of experience-dependent translation of alpha-CaMKII mRNA at synapses
    L Wu
    Department of Molecular Genetics and Microbiology, University of Massachusetts Medical School, Worcester 01655, USA
    Neuron 21:1129-39. 1998
    ..In the intact brain, visual experience induces alpha-CaMKII mRNA polyadenylation and translation, suggesting that this process likely occurs at synapses...