Eric K Richfield

Summary

Affiliation: University of Rochester
Country: USA

Publications

  1. ncbi Selective loss of striatal preprotachykinin neurons in a phenocopy of Huntington's disease
    Eric K Richfield
    Department of Pathology and Laboratory Medicine and Center for Aging and Developmental Biology, University of Rochester School of Medicine and Dentistry, Rochester, New York, USA
    Mov Disord 17:327-32. 2002
  2. ncbi The effect of developmental exposure to the fungicide triadimefon on behavioral sensitization to triadimefon during adulthood
    Ruth Reeves
    Department of Environmental Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    Toxicol Appl Pharmacol 200:54-63. 2004
  3. ncbi A fetal risk factor for Parkinson's disease
    Brian K Barlow
    Department of Pathology and Laboratory Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA
    Dev Neurosci 26:11-23. 2004
  4. ncbi Developmental exposure to the pesticides paraquat and maneb and the Parkinson's disease phenotype
    Mona Thiruchelvam
    Department of Environmental Medicine, University of Rochester School of Medicine and Dentistry, NY 14642, USA
    Neurotoxicology 23:621-33. 2002
  5. ncbi Behavioral sensitization and long-term neurochemical alterations associated with the fungicide triadimefon
    Ruth Reeves
    Department of Environmental Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    Pharmacol Biochem Behav 76:315-26. 2003
  6. ncbi Behavioral and neurochemical effects of wild-type and mutated human alpha-synuclein in transgenic mice
    Eric K Richfield
    Department of Pathology and Lab Medicine, University of Rochester School of Medicine and Dentistry, 601 Elmwood Avenue, Rochester, New York 14642, USA
    Exp Neurol 175:35-48. 2002
  7. ncbi Increased synaptosomal dopamine content and brain concentration of paraquat produced by selective dithiocarbamates
    Brian K Barlow
    Department of Pathology, University of Rochester School of Medicine and Dentistry, 601 Elmwood Avenue, Rochester, NY 14642, USA
    J Neurochem 85:1075-86. 2003
  8. ncbi Age-related irreversible progressive nigrostriatal dopaminergic neurotoxicity in the paraquat and maneb model of the Parkinson's disease phenotype
    Mona Thiruchelvam
    Department of Environmental Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    Eur J Neurosci 18:589-600. 2003
  9. ncbi Reporter gene transfer induces apoptosis in primary cortical neurons
    Eric R Detrait
    Center for Aging and Developmental Biology, Department of Pathology and Laboratory Medicine, University of Rochester, Rochester, New York 14642, USA
    Mol Ther 5:723-30. 2002
  10. ncbi Overexpression of superoxide dismutase or glutathione peroxidase protects against the paraquat + maneb-induced Parkinson disease phenotype
    Mona Thiruchelvam
    Department of Biochemistry, and Environmental and Occupational Health Sciences Institute, University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, 675 Hoes Lane, Piscataway, NJ 08854, USA
    J Biol Chem 280:22530-9. 2005

Collaborators

Detail Information

Publications14

  1. ncbi Selective loss of striatal preprotachykinin neurons in a phenocopy of Huntington's disease
    Eric K Richfield
    Department of Pathology and Laboratory Medicine and Center for Aging and Developmental Biology, University of Rochester School of Medicine and Dentistry, Rochester, New York, USA
    Mov Disord 17:327-32. 2002
    ..This case demonstrates the existence of one type of striatal lesion that may produce a clinical picture similar to HD, and raises the possibility of a rare hereditary disease that mimics HD...
  2. ncbi The effect of developmental exposure to the fungicide triadimefon on behavioral sensitization to triadimefon during adulthood
    Ruth Reeves
    Department of Environmental Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    Toxicol Appl Pharmacol 200:54-63. 2004
    ..These results indicate for the first time that TDF may be considered an environmental risk factor for developmental dopaminergic neurotoxicity...
  3. ncbi A fetal risk factor for Parkinson's disease
    Brian K Barlow
    Department of Pathology and Laboratory Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA
    Dev Neurosci 26:11-23. 2004
    ..This study implicates a role for developmental neurotoxicant exposure in the induction of neurodegenerative disorders such as PD...
  4. ncbi Developmental exposure to the pesticides paraquat and maneb and the Parkinson's disease phenotype
    Mona Thiruchelvam
    Department of Environmental Medicine, University of Rochester School of Medicine and Dentistry, NY 14642, USA
    Neurotoxicology 23:621-33. 2002
    ....
  5. ncbi Behavioral sensitization and long-term neurochemical alterations associated with the fungicide triadimefon
    Ruth Reeves
    Department of Environmental Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    Pharmacol Biochem Behav 76:315-26. 2003
    ..Thus, TDF exposure may serve as an environmental risk factor for DA system dysfunctions...
  6. ncbi Behavioral and neurochemical effects of wild-type and mutated human alpha-synuclein in transgenic mice
    Eric K Richfield
    Department of Pathology and Lab Medicine, University of Rochester School of Medicine and Dentistry, 601 Elmwood Avenue, Rochester, New York 14642, USA
    Exp Neurol 175:35-48. 2002
    ..Expression of hm2alpha-SYN adversely affects the integrity of dopaminergic terminals and leads to age-related declines in motor coordination and dopaminergic markers...
  7. ncbi Increased synaptosomal dopamine content and brain concentration of paraquat produced by selective dithiocarbamates
    Brian K Barlow
    Department of Pathology, University of Rochester School of Medicine and Dentistry, 601 Elmwood Avenue, Rochester, NY 14642, USA
    J Neurochem 85:1075-86. 2003
    ..These results suggest that selective dithiocarbamates may alter the kinetics of different endogenous and exogenous compounds to enhance their neurotoxicity...
  8. ncbi Age-related irreversible progressive nigrostriatal dopaminergic neurotoxicity in the paraquat and maneb model of the Parkinson's disease phenotype
    Mona Thiruchelvam
    Department of Environmental Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    Eur J Neurosci 18:589-600. 2003
    ..Collectively, these data demonstrate enhanced sensitivity of the ageing nigrostriatal dopamine pathway to these pesticides, particularly paraquat + maneb, resulting in irreversible and progressive neurotoxicity...
  9. ncbi Reporter gene transfer induces apoptosis in primary cortical neurons
    Eric R Detrait
    Center for Aging and Developmental Biology, Department of Pathology and Laboratory Medicine, University of Rochester, Rochester, New York 14642, USA
    Mol Ther 5:723-30. 2002
    ..This work underscores the need for careful design of gene expression constructs. Moreover, in studies where cell injury or toxicity is being evaluated, their use should be carefully considered...
  10. ncbi Overexpression of superoxide dismutase or glutathione peroxidase protects against the paraquat + maneb-induced Parkinson disease phenotype
    Mona Thiruchelvam
    Department of Biochemistry, and Environmental and Occupational Health Sciences Institute, University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, 675 Hoes Lane, Piscataway, NJ 08854, USA
    J Biol Chem 280:22530-9. 2005
    ....
  11. pmc Developmental pesticide models of the Parkinson disease phenotype
    Deborah A Cory-Slechta
    Environmental and Occupational Health Sciences Institute, University of Medicine and Dentistry of New Jersey, Piscataway, NJ 07920, USA
    Environ Health Perspect 113:1263-70. 2005
    ..As such, this hypothesis presents a biologic strategy for identifying potentially significant neurotoxic mixtures for hazard identification in future studies...
  12. ncbi Developmental pesticide exposures and the Parkinson's disease phenotype
    Deborah A Cory-Slechta
    Environmental and Occupational Health Sciences Institute, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, 170 Frelinghuysen Road, Piscataway, NJ 08854, USA
    Birth Defects Res A Clin Mol Teratol 73:136-9. 2005
    ..In addition, they demonstrate the fact that silent neurotoxicity produced by developmental insults can be unmasked by challenges later during life as well as the potential for cumulative neurotoxicity over the life span...
  13. ncbi Zfp36l3, a rodent X chromosome gene encoding a placenta-specific member of the Tristetraprolin family of CCCH tandem zinc finger proteins
    Perry J Blackshear
    Laboratory of Neurobiology, Office of Clinical Research, National Institute of Environmental Health Sciences, North Carolina 27709, USA
    Biol Reprod 73:297-307. 2005
    ..Its presumed role in placental physiology may be unique to rodents or murine rodents, but this role may be subsumed by other family members in nonrodents...
  14. ncbi The gestational environment and Parkinson's disease: evidence for neurodevelopmental origins of a neurodegenerative disorder
    Brian K Barlow
    MD PhD Program, Graduate Program in Neuroscience, UMDNJ RWJMS and Rutgers, USA
    Reprod Toxicol 23:457-70. 2007
    ..Additionally, challenges in studying the neurodevelopmental basis of neurodegeneration experimentally and epidemiologically are presented...