Research Topics
| David RichardsonSummaryAffiliation: University of North Carolina Country: USA Publications
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Publications
Random effects regression models for trends in standardised mortality ratiosDavid B Richardson
Department of Epidemiology, School of Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
Occup Environ Med 70:133-9. 2013..However, because the distribution of people with respect to age usually changes as calendar time advances, comparisons of SMRs across calendar periods can produce misleading results...
The effect of rate denominator source on US fatal occupational injury rate estimatesDavid Richardson
Department of Epidemiology, School of Public Health, University of North Carolina, Chapel Hill, North Carolina 27599 8050, USA
Am J Ind Med 46:261-70. 2004..The Decennial Census of Population provides an alternative source for rate denominator information. We investigate the comparability of fatal injury rates derived using these two sources of rate denominator information...- Time-related aspects of the healthy worker survivor effectDavid Richardson
Department of Epidemiology, School of Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
Ann Epidemiol 14:633-9. 2004..We use simulations and an empirical example to demonstrate that time-since-termination can be a confounding factor in analyses of occupational-exposure-mortality associations... 
The impact of exposure categorisation for grouped analyses of cohort dataD B Richardson
Department of Epidemiology, School of Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 8050, USA
Occup Environ Med 61:930-5. 2004..In order to estimate a dose-response trend, a researcher must decide how to categorise exposures and how to assign scores to exposure groups...- An incidence density sampling program for nested case-control analysesD B Richardson
Department of Epidemiology, School of Public Health, University of North Carolina, Chapel Hill, NC 27599 8050, USA
Occup Environ Med 61:e59. 2004..In order to obtain unbiased estimates of relative risk, controls should be selected by incidence density sampling, which involves matching each case to a sample of those who are at risk at the time of case occurrence... - Adult hemoglobin levels at birth and risk of sudden infant death syndromeDavid B Richardson
Department of Epidemiology, School of Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 8050, USA
Arch Pediatr Adolesc Med 158:366-71. 2004..Delayed or faulty transition to the production of adult hemoglobin might play a role in the etiology of sudden infant death syndrome (SIDS)... 
Ionizing radiation and chronic lymphocytic leukemiaDavid B Richardson
Department of Epidemiology, School of Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 8050, USA
Environ Health Perspect 113:1-5. 2005..Our findings in this review suggest that there is not a persuasive basis for the conclusion that CLL is a nonradiogenic form of cancer...- Power calculations for survival analyses via Monte Carlo estimationDavid B Richardson
Department of Epidemiology, School of Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 8050, USA
Am J Ind Med 44:532-9. 2003..These conditions are not easily accommodated by available software or published formulas for power calculation... - Investigating time patterns of variation in radiation cancer associationsD B Richardson
Department of Epidemiology, School of Public Health, University of North Carolina, Chapel Hill, NC 27599 8050, USA
Occup Environ Med 62:551-8. 2005..The authors present several simple models that may be used to evaluate the influence of time since exposure or age at exposure on cancer incidence or mortality in an occupational cohort... - Effects of exposure measurement error when an exposure variable is constrained by a lower limitDavid B Richardson
Department of Epidemiology, School of Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 8050, USA
Am J Epidemiol 157:355-63. 2003.... - Fatal occupational injury rates in southern and non-southern States, by race and Hispanic ethnicityDavid B Richardson
Department of Epidemiology, School of Public Health, CB No 8050, Bank of America Plaza, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 8050, USA
Am J Public Health 94:1756-61. 2004..We investigated fatal occupational injury rates in the United States by race and Hispanic ethnicity during the period 1990-1996... - Increased lung cancer mortality among chrysotile asbestos textile workers is more strongly associated with exposure to long thin fibresDana Loomis
Department of Epidemiology, College of Public Health, 984395 University of Nebraska Medical Center, Omaha, NE 68198, USA
Occup Environ Med 69:564-8. 2012..Animal data and physical models suggest that the carcinogenicity of asbestos fibres is related to their size and shape... - Lung cancer mortality in North Carolina and South Carolina chrysotile asbestos textile workersLeslie Elliott
Department of Epidemiology, College of Public Health, University of Nebraska Medical Center, Omaha, Nebraska, USA
Occup Environ Med 69:385-90. 2012..The authors conducted pooled analyses of the cohorts and investigated the exposure-disease relationship using uniform cohort inclusion criteria and statistical methods... - Illustrating bias due to conditioning on a colliderStephen R Cole
Department of Epidemiology, UNC Gillings School of Global Public Health, Chapel Hill, NC, USA
Int J Epidemiol 39:417-20. 2010..In both examples, conditioning on the common effect imparts an association between two otherwise independent variables; we call this selection bias... - Occupational injuries among aides and nurses in acute careR L Rodríguez-Acosta
Department of Epidemiology, School of Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
Am J Ind Med 52:953-64. 2009..Our objective was to assess risk of work-related injuries in an acute care setting while contrasting injuries of aides and nurses... - Detecting disease outbreaks using local spatiotemporal methodsYingqi Zhao
Department of Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA
Biometrics 67:1508-17. 2011.... - Plutonium-related work and cause-specific mortality at the United States Department of Energy Hanford SiteSteve Wing
Department of Epidemiology, School of Public Health, University of North Carolina, Chapel Hill, North Carolina 27599 7400, USA
Am J Ind Med 45:153-64. 2004..Health effects of working with plutonium remain unclear. Plutonium workers at the United States Department of Energy (US-DOE) Hanford Site in Washington State, USA were evaluated for increased risks of cancer and non-cancer mortality... - Dose reconstruction for an occupational cohort at the Savannah River nuclear facility: evaluation of a hybrid methodGhassan Hamra
Department of Environmental Sciences and Engineering, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 7400, USA
Radiat Prot Dosimetry 131:188-97. 2008..The collective estimated tritium dose was 4319 mSv compared with the total known tritium dose of 17 382 mSv. The correlation (R2) of estimated tritium dose with known tritium dose was 0.68... - Ionizing radiation and leukemia mortality among Japanese Atomic Bomb Survivors, 1950-2000David Richardson
Department of Epidemiology, School of Public Health, University of North Carolina, Chapel Hill, NC 27599, USA
Radiat Res 172:368-82. 2009..005 Gy was 0.34, suggesting that the effect of the atomic bombings on leukemia mortality has persisted in this cohort for more than five decades... - Discrete time hazards models for occupational and environmental cohort analysesD B Richardson
Department of Epidemiology, School of Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA
Occup Environ Med 67:67-71. 2010..To discuss the use of discrete time hazards models for the analysis of occupational and environmental cohort data... - Methods for investigating age differences in the effects of prolonged exposuresD B Richardson
Department of Epidemiology, School of Public Health, University of North Carolina at Chapel Hill 27599 8050, USA
Am J Ind Med 33:123-30. 1998..These methods are illustrated with occupational cohort data for employees of Oak Ridge National Laboratory. The methods presented in this paper should facilitate examination of the effects of aging on sensitivity to prolonged exposures... - The impact on relative risk estimates of inconsistencies between ICD-9 and ICD-10D B Richardson
Department of Epidemiology, School of Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
Occup Environ Med 63:734-40. 2006..The ratio of these relative risks is referred to as the coefficient of bias... - Poisson regression analysis of ungrouped dataD Loomis
Department of Epidemiology, University of North Carolina, Chapel Hill, NC 27599 7435, USA
Occup Environ Med 62:325-9. 2005..It is typically implemented as a grouped method of data analysis in which all exposure and covariate information is categorised and person-time and events are tabulated... - Greater sensitivity to ionizing radiation at older age: follow-up of workers at Oak Ridge National Laboratory through 1990D B Richardson
Department of Epidemiology, School of Public Health, University of North Carolina at Chapel Hill 27599 8050, USA
Int J Epidemiol 28:428-36. 1999..Since biological changes occur as adults age, a potentially important question in these investigations is whether sensitivity to the carcinogenic effects of ionizing radiation changes with age at exposure... - Age at exposure to ionising radiation and cancer mortality among Hanford workers: follow up through 1994S Wing
Department of Epidemiology, School of Public Health, University of North Carolina, Chapel Hill, NC 27599 7400, USA
Occup Environ Med 62:465-72. 2005..Studies of workers at the plutonium production factory in Hanford, WA have led to conflicting conclusions about the role of age at exposure as a modifier of associations between ionising radiation and cancer... - Radiation and mortality of workers at Oak Ridge National Laboratory: positive associations for doses received at older agesD B Richardson
Department of Epidemiology, School of Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 8050, USA
Environ Health Perspect 107:649-56. 1999..These findings suggest increases in cancer mortality associated with low-level external exposure to ionizing radiation and potentially greater sensitivity to the carcinogenic effects of ionizing radiation with older ages at exposure... - Deindustrialisation and the long term decline in fatal occupational injuriesD Loomis
Department of Epidemiology, School of Public Health, University of North Carolina, Chapel Hill, NC 27599 7435, USA
Occup Environ Med 61:616-21. 2004..To examine the extent to which deindustrialisation accounts for long term trends in occupational injury risk in the United States... - Cancer risk from low-level ionizing radiation: the role of age at exposureD B Richardson
Department of Epidemiology, School of Public Health, University of North Carolina, Chapel Hill 27599-8050, USA
Occup Med 16:191-218. 2001..Further attention to modifying factors in radiation-cancer associations, such as age at exposure, may help to protect workers and the public by improving our understanding of sensitivity variation within populations... - Physical assault among nursing staff employed in acute careR L Rodríguez-Acosta
Department of Epidemiology, School of Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
Work 35:191-200. 2010..63, 95% CI: 1.51-8.71) units. Interventions targeting Psychiatry, Neurology, and Rehabilitation units, and younger and newly hired staff are warranted. More detailed data are needed to develop targeted interventions... - Integrating informative priors from experimental research with Bayesian methods: an example from radiation epidemiologyGhassan Hamra
Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 7435, USA
Epidemiology 24:90-5. 2013..We present a method to help bridge the gap between animal and cellular studies and epidemiologic research by specification of an order-constrained prior. We illustrate this approach using an example from radiation epidemiology... - Relation between malodor, ambient hydrogen sulfide, and health in a community bordering a landfillChristopher D Heaney
Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, CB 7435, Chapel Hill, NC 27599 7435, USA
Environ Res 111:847-52. 2011..Municipal solid waste landfills are sources of air pollution that may affect the health and quality of life of neighboring communities... - RNABC: forward kinematics to reduce all-atom steric clashes in RNA backboneXueyi Wang
Department of Computer Science, UNC Chapel Hill, Chapel Hill, NC 27599 3175, USA
J Math Biol 56:253-78. 2008..Thus, even for these worst cases, nearly half the time RNABC suggested corrections suitable to initiate further crystallographic refinement. The program is available from http://kinemage.biochem.duke.edu ... - Fatal occupational injuries among self-employed workers in North CarolinaMaria C Mirabelli
Department of Epidemiology, School of Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599-7435, USA
Am J Ind Med 44:182-90. 2003.... - Heat-related fatalities in North CarolinaMaria C Mirabelli
University of North Carolina at Chapel Hill, School of Public Health, Department of Epidemiology, CB 8050, Chapel Hill, NC 27599 8050, USA
Am J Public Health 95:635-7. 2005..Of the occupational heat-related fatalities (n=40), 45% occurred among farm laborers, many of whom died unnoticed and without medical attention... - Use of multiple cause of death data in cancer mortality analysesDavid B Richardson
Department of Epidemiology, School of Public Health, University of North Carolina, Chapel Hill, North Carolina 27599 7435, USA
Am J Ind Med 49:683-9. 2006..In a cancer mortality study, the decision of whether to define a study outcome via underlying cause of death (UCD) or via multiple cause of death (MCD) information may impact relative risk (RR) estimates and associated confidence intervals... - Lung cancer mortality among workers at a nuclear materials fabrication plantDavid B Richardson
Department of Epidemiology, School of Public Health, University of North Carolina, Chapel Hill, North Carolina 27599 7435, USA
Am J Ind Med 49:102-11. 2006.... - Evaluation of external radiation dosimetry records at the Savannah River Site, 1951-1989David B Richardson
Department of Epidemiology, School of Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
J Expo Sci Environ Epidemiol 17:13-24. 2007..7 person-Sv. The consistency of dosimetry practices at SRS and the completeness of historical dosimetry records are supportive of their use in epidemiologic research... - Analyses of case-control data for additional outcomesDavid B Richardson
Department of Epidemiology, School of Public Health, University of North Carolina, Chapel Hill, NC 27599 7435, USA
Epidemiology 18:441-5. 2007..Weighted logistic regression methods are readily implemented using available statistical packages... - Childhood leukemia in the vicinity of the Geesthacht nuclear establishments near Hamburg, GermanyWolfgang Hoffmann
Institute for Community Medicine, Section Epidemiology of Health Care and Community Health, Ernst Moritz Arndt University of Greifswald, Greifswald, Germany
Environ Health Perspect 115:947-52. 2007..Since then, several new cases have been reported. Recently a possible accidental release of radionuclides in 1986 was hypothesized... - Leukemia mortality among workers at the Savannah River SiteDavid B Richardson
Department of Epidemiology, School of Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
Am J Epidemiol 166:1015-22. 2007..The temporal patterns of association appear consistent with those in studies of populations exposed at higher dose rates... - Temporal patterns of association between cigarette smoking and leukemia riskDavid B Richardson
Department of Epidemiology, School of Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
Cancer Causes Control 19:43-50. 2008..To evaluate variation in smoking-related leukemia risk with time-since-exposure... - Mortality among workers at the Savannah River SiteDavid B Richardson
Department of Epidemiology, School of Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA
Am J Ind Med 50:881-91. 2007..We therefore compared the observed deaths among workers to expectations based upon death rates for referent populations... - Occupational risk factors for non-Hodgkin's lymphoma: a population-based case-control study in Northern GermanyDavid B Richardson
Department of Epidemiology, School of Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA
Am J Ind Med 51:258-68. 2008..To identify occupational factors associated with non-Hodgkin's lymphoma (NHL)... - Temporal variation in the association between benzene and leukemia mortalityDavid B Richardson
Department of Epidemiology, School of Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA
Environ Health Perspect 116:370-4. 2008..Benzene is a human carcinogen. Exposure to benzene occurs in occupational and environmental settings... - Re: solid cancer incidence in atomic bomb survivors exposed in utero or as young childrenDavid B Richardson
J Natl Cancer Inst 100:1482-3. 2008
Research Grants
- Cohort analysis methods for occupational cancer studiesDavid B Richardson; Fiscal Year: 2010....
- Long-term Effects of Occupational Radiation ExposuresDavid Richardson; Fiscal Year: 2009....
- Cohort analysis methods for occupational cancer studiesDavid Richardson; Fiscal Year: 2009..The proposal addresses the NORA priority area on cancer research methods. The results of the proposed research will further improve the analytic methods used in occupational cancer studies. ..
- Mechanistic models in occupational cancer epidemiologyDavid Richardson; Fiscal Year: 2007..The expectation is that use of knowledge about biological processes of carcinogenesis will improve the ability to identify and understand the effects of occupational carcinogens. ..
- Cohort analysis methods for occupational cancer studiesDavid Richardson; Fiscal Year: 2007..The proposal addresses the NORA priority area on cancer research methods. The results of the proposed research will further improve the analytic methods used in occupational cancer studies. ..
- Chrysotile: New Exposure Indices and Cancer EpidemiologyDavid Richardson; Fiscal Year: 2006..abstract_text> ..
- Susceptibility and occupational radiation risksDavid Richardson; Fiscal Year: 2004..In this way, the proposed work will substantially strengthen the available epidemiological information about low level radiation effects in USDOE cohorts. ..
- Time-Factors in Exposure Effects Among Uranium WorkersDavid Richardson; Fiscal Year: 2003....
- Long-term Effects of Occupational Radiation ExposuresDavid B Richardson; Fiscal Year: 2010....