Richardson B. Epigenetically Altered T Cells Contribute to Lupus Flares. Cells. 2019;8: pubmed publisher
..Transcriptional analyses of this subset reveal proteins uniquely expressed by this subset, which may serve as therapeutic to deplete these cells, treating lupus flares. ..
Richardson B. DNA methylation and autoimmune disease. Clin Immunol. 2003;109:72-9 pubmed
..T cells from patients with active lupus have evidence for most if not all of the same methylation abnormalities, suggesting that abnormal DNA methylation plays a role in idiopathic human lupus as well. ..
Richardson B, Sawalha A, Ray D, Yung R. Murine models of lupus induced by hypomethylated T cells (DNA hypomethylation and lupusâ€¦). Methods Mol Biol. 2012;900:169-80 pubmed publisher
..This chapter describes the protocols for inducing autoreactivity in murine T cells in vitro and for inducing autoimmunity in vivo using an adoptive transfer approach or transgenic animal models. ..