Research Topics
Species | A RichardsonSummaryAffiliation: University of Chicago Country: USA Publications
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Detail Information
Publications
HLA and mate choice in humansC Ober
Center for Medical Genetics, Department of Obstetrics and Gynecology, The University of Chicago, IL 60637, USA
Am J Hum Genet 61:497-504. 1997..018). These results are consistent with the conclusion that Hutterite mate choice is influenced by HLA haplotypes, with an avoidance of spouses with haplotypes that are the same as one's own...
A second-generation genomewide screen for asthma-susceptibility alleles in a founder populationC Ober
Department of Human Genetics, The University of Chicago, Chicago, IL, 60637, USA
Am J Hum Genet 67:1154-62. 2000....
Contributing factors to the pathobiology. The genetics of asthmaC Ober
Department of Human Genetics, University of Chicago, Illinois, USA
Clin Chest Med 21:245-61. 2000....
Variation in the interleukin 4-receptor alpha gene confers susceptibility to asthma and atopy in ethnically diverse populationsC Ober
Department of Human Genetics, University of Chicago, Chicago, IL 60636, USA
Am J Hum Genet 66:517-26. 2000..Overall, these data suggest that the IL4RA gene is an atopy- and asthma-susceptibility locus but that variation outside the coding region of the gene influences susceptibility...
Inbreeding effects on fertility in humans: evidence for reproductive compensationC Ober
Departments of Human Genetics and Obstetrics and Gynecology, The University of Chicago, IL 60637, USA
Am J Hum Genet 64:225-31. 1999..This recent reproductive strategy would facilitate the maintenance of recessive alleles and contribute to an overall decline in fertility in the population...
Genome-wide search for asthma susceptibility loci in a founder population. The Collaborative Study on the Genetics of AsthmaC Ober
Department of Human Genetics, University of Chicago, 924 East 57th Street, Chicago, IL 60637, USA
Hum Mol Genet 7:1393-8. 1998....
HLA-G1 protein expression is not essential for fetal survivalC Ober
Center for Medical Genetics, Department of Obstetrics and Gynecology, The University of Chicago, IL 60637, USA
Placenta 19:127-32. 1998..These data indicate that expression of HLA-G1 protein is not essential for fetal survival...
HLA-G polymorphisms: neutral evolution or novel function?C Ober
Department of Obstetrics and Gynecology, University of Chicago, IL 60637, USA
J Reprod Immunol 36:1-21. 1997..In this paper we review some of the novel features of HLA-G, with particular reference to polymorphic variants in the gene, and discuss the implications of these features for the potential function and evolutionary history of HLA-G...
Nucleotide diversity of the TNF gene region in an African villageA Richardson
Wellcome Trust Centre for Human Genetics, Oxford University, UK
Genes Immun 2:343-8. 2001..007). We conclude that, at the TNF locus, the nucleotide diversity found within a single African village is similar to the global value for human autosomal genes sampled across different continents...
Association of accelerated erosive rheumatoid arthritis with a polymorphism that alters NF-kappaB binding to the TNF promoter regionI A Udalova
Rheumatology (Oxford) 41:830-1. 2002
Molecular cloning, expression and characterization of the human serine/threonine kinase Akt-3S Masure
Department of Biotechnology, Janssen Research Foundation, Beerse, Belgium
Eur J Biochem 265:353-60. 1999..These observations suggest that Akt-3 is a promising target for the discovery of novel chemotherapeutic agents which do not interfere with insulin signalling...
No association between interferon-gamma receptor-1 gene polymorphism and pulmonary tuberculosis in a Gambian population sampleA A Awomoyi
MRC Laboratories, Fajara, The Gambia
Thorax 59:291-4. 2004..The role of genetic variation in IFNGR1 in susceptibility to common mycobacterial diseases such as pulmonary TB in outbred populations has not previously been investigated...
The role of inflammatory bowel disease susceptibility loci in multiple sclerosis and systemic lupus erythematosusP L De Jager
Center for Neurologic Diseases, Department of Neurology, Harvard Medical School and Brigham and Women s Hospital, MA, USA
Genes Immun 7:327-34. 2006..Our data, therefore, suggest that both the CARD15 gene and the IBD5 locus may have a role as general susceptibility loci for certain common, genetically complex inflammatory diseases...
