Pamela L Rice

Summary

Affiliation: University of Colorado Health Sciences Center
Country: USA

Publications

  1. ncbi request reprint Sulindac metabolites induce caspase- and proteasome-dependent degradation of beta-catenin protein in human colon cancer cells
    Pamela L Rice
    Department of Medicine, University of Colorado Health Sciences Center, Denver, CO 80262, USA
    Mol Cancer Ther 2:885-92. 2003
  2. ncbi request reprint Inhibition of extracellular-signal regulated kinases 1/2 is required for apoptosis of human colon cancer cells in vitro by sulindac metabolites
    Pamela L Rice
    Veterans Administration Medical Center, Department of Medicine, University of Colorado Health Sciences Center, and University of Colorado Comprehensive Cancer Center, Denver, Colorado 80262, USA
    Cancer Res 64:8148-51. 2004
  3. ncbi request reprint Sulindac independently modulates extracellular signal-regulated kinase 1/2 and cyclic GMP-dependent protein kinase signaling pathways
    Pamela L Rice
    Veterans Affairs Medical Center Denver, CO, USA
    Mol Cancer Ther 5:746-54. 2006
  4. ncbi request reprint Sulindac sulfide inhibits epidermal growth factor-induced phosphorylation of extracellular-regulated kinase 1/2 and Bad in human colon cancer cells
    Pamela L Rice
    Division of Gastroenterology, Department of Medicine, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
    Cancer Res 63:616-20. 2003
  5. pmc Regulation of cytokine-induced prostanoid and nitric oxide synthesis by extracellular signal–regulated kinase 1/2 in lung epithelial cells
    Pamela L Rice
    Veterans Affairs Medical Center, Denver, Colorado, USA
    Exp Lung Res 36:558-71. 2010
  6. doi request reprint Wound healing after trauma may predispose to lung cancer metastasis: review of potential mechanisms
    Nicholas D Walter
    Division of Pulmonary Sciences and Critical Care Medicine, University of Colorado Denver Anschutz Medical Campus, Denver, Colorado, USA
    Am J Respir Cell Mol Biol 44:591-6. 2011

Collaborators

Detail Information

Publications6

  1. ncbi request reprint Sulindac metabolites induce caspase- and proteasome-dependent degradation of beta-catenin protein in human colon cancer cells
    Pamela L Rice
    Department of Medicine, University of Colorado Health Sciences Center, Denver, CO 80262, USA
    Mol Cancer Ther 2:885-92. 2003
    ....
  2. ncbi request reprint Inhibition of extracellular-signal regulated kinases 1/2 is required for apoptosis of human colon cancer cells in vitro by sulindac metabolites
    Pamela L Rice
    Veterans Administration Medical Center, Department of Medicine, University of Colorado Health Sciences Center, and University of Colorado Comprehensive Cancer Center, Denver, Colorado 80262, USA
    Cancer Res 64:8148-51. 2004
    ..These results suggest that inhibition of MEK/ERK signaling is necessary for the induction of apoptosis by sulindac metabolites...
  3. ncbi request reprint Sulindac independently modulates extracellular signal-regulated kinase 1/2 and cyclic GMP-dependent protein kinase signaling pathways
    Pamela L Rice
    Veterans Affairs Medical Center Denver, CO, USA
    Mol Cancer Ther 5:746-54. 2006
    ..Using similar combinatorial approaches in vivo may provide more effective, less toxic chemopreventive and chemotherapeutic strategies. Such therapies could dramatically reduce the incidence and death rate from colorectal cancer...
  4. ncbi request reprint Sulindac sulfide inhibits epidermal growth factor-induced phosphorylation of extracellular-regulated kinase 1/2 and Bad in human colon cancer cells
    Pamela L Rice
    Division of Gastroenterology, Department of Medicine, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
    Cancer Res 63:616-20. 2003
    ..The ability of sulindac to block ERK1/2 signaling by the EGF receptor may account for at least part of its potent growth-inhibitory effects against cancer cells...
  5. pmc Regulation of cytokine-induced prostanoid and nitric oxide synthesis by extracellular signal–regulated kinase 1/2 in lung epithelial cells
    Pamela L Rice
    Veterans Affairs Medical Center, Denver, Colorado, USA
    Exp Lung Res 36:558-71. 2010
    ..Since tumor-derived cells were more sensitive than nontumorigenic cells to the antiproliferative effects of U0126, MEK1/2 inhibition may serve as an attractive chemotherapeutic target...
  6. doi request reprint Wound healing after trauma may predispose to lung cancer metastasis: review of potential mechanisms
    Nicholas D Walter
    Division of Pulmonary Sciences and Critical Care Medicine, University of Colorado Denver Anschutz Medical Campus, Denver, Colorado, USA
    Am J Respir Cell Mol Biol 44:591-6. 2011
    ..Further exploration of post-traumatic inflammatory oncotaxis may elucidate fundamental mechanisms of metastasis and could provide novel strategies to prevent cancer metastasis...