Research Topics
Species | J S RhodesSummaryAffiliation: University of Illinois Country: USA Publications
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Publications
Mouse inbred strain differences in ethanol drinking to intoxicationJ S Rhodes
Department of Psychology, University of Illinois at Urbana Champaign, Champaign, IL, USA
Genes Brain Behav 6:1-18. 2007..We discuss applications of the model for finding genes that predispose pharmacologically significant drinking in mice...
Acute effects of naltrexone and GBR 12909 on ethanol drinking-in-the-dark in C57BL/6J miceN K Kamdar
Department of Psychology, Beckman Institute, Urbana, IL 61801, USA
Psychopharmacology (Berl) 192:207-17. 2007..The test consists of replacing the water with 20% ethanol in the home cage for 2 or 4 h early during the dark phase of the light/dark cycle...
Acute locomotor responses to cocaine in adolescents vs. adults from four divergent inbred mouse strainsJ A Zombeck
Department of Psychology, The Beckman Institute, University of Illinois at Urbana Champaign, Urbana, IL 61801, USA
Genes Brain Behav 9:892-8. 2010..Future comparative studies could discover biological differences between strains that explain age differences in cocaine sensitivity...
Induction of c-Fos, Zif268, and Arc from acute bouts of voluntary wheel running in new and pre-existing adult mouse hippocampal granule neuronsP J Clark
Department of Psychology, The Beckman Institute, 405 N Mathews Avenue, University of Illinois at Urbana Champaign, Urbana, IL 61801, USA
Neuroscience 184:16-27. 2011..The results suggest that robust movements, like running, are necessary to stimulate IEG expression and neurogenesis. Moreover, results suggest new neurons from running may be processing information about running behavior itself...
Patterns of neural activity associated with differential acute locomotor stimulation to cocaine and methamphetamine in adolescent versus adult male C57BL/6J miceJ A Zombeck
Department of Psychology, The Beckman Institute, University of Illinois at Urbana Champaign, Urbana, IL 61801, USA
Neuroscience 165:1087-99. 2010..Future research will identify the molecular and cellular events that are responsible for the differential psychostimulant-induced patterns of brain activation and behavior observed in adolescent versus adult mice...
Evaluation of a pharmacokinetic hypothesis for reduced locomotor stimulation from methamphetamine and cocaine in adolescent versus adult male C57BL/6J miceJonathan A Zombeck
Department of Psychology, The Beckman Institute, University of Illinois at Urbana Champaign, 405 N Mathews Ave, Urbana, IL 61801, USA
Psychopharmacology (Berl) 201:589-99. 2009..Adolescent mice display reduced locomotor stimulation to cocaine and amphetamine compared to adults, but the mechanisms are not known...
Aerobic exercise is the critical variable in an enriched environment that increases hippocampal neurogenesis and water maze learning in male C57BL/6J miceM L Mustroph
Neuroscience Program, The Beckman Institute for Advanced Science and Technology, 405 North Mathews Avenue, University of Illinois at Urbana Champaign, Urbana, IL 61801, USA
Neuroscience 219:62-71. 2012....
Genetic influences on exercise-induced adult hippocampal neurogenesis across 12 divergent mouse strainsP J Clark
Department of Psychology, University of Illinois, Beckman Institute, Urbana, IL 61801, USA
Genes Brain Behav 10:345-53. 2011..exercise-induced neurogenesis. Genetic contributions to exercise-induced hippocampal neurogenesis suggest that it may be possible to identify genes and pathways associated with enhanced neuroplastic responses to exercise...
Intact neurogenesis is required for benefits of exercise on spatial memory but not motor performance or contextual fear conditioning in C57BL/6J miceP J Clark
Department of Psychology, The Beckman Institute, University of Illinois at Urbana Champaign, Urbana, IL 61801, USA
Neuroscience 155:1048-58. 2008..Results support the hypothesis that intact exercise-induced hippocampal neurogenesis is required for improved spatial memory, but not motor performance or contextual fear in C57BL/6J mice...
Adult hippocampal neurogenesis and c-Fos induction during escalation of voluntary wheel running in C57BL/6J micePeter J Clark
Department of Psychology, The Beckman Institute, University of Illinois at Urbana Champaign, 405 N Mathews Ave, Urbana, IL 61801, USA
Behav Brain Res 213:246-52. 2010..We conclude that sustained running maintains a stable rate of neurogenesis above sedentary via activity-dependent increases in differentiation and survival, not proliferation, of progenitor cells in the C57BL/6J model...
Neuroanatomical specificity of conditioned responses to cocaine versus food in miceJonathan A Zombeck
Department of Psychology, The Beckman Institute, 405 N Mathews Ave, University of Illinois at Urbana Champaign, Urbana, IL 61801, USA
Physiol Behav 93:637-50. 2008..One difference between drugs and natural reinforcers may be lack of feedback from the periphery for drugs which may circumvent control from the hypothalamus in the development of reinforcement circuits...
Functional analysis of neurovascular adaptations to exercise in the dentate gyrus of young adult mice associated with cognitive gainPeter J Clark
Department of Psychology, The Beckman Institute, University of Illinois at Urbana Champaign, Urbana, IL 61801, USA
Hippocampus 19:937-50. 2009....
A similar pattern of neuronal Fos activation in 10 brain regions following exposure to reward- or aversion-associated contextual cues in miceZachary V Johnson
Department of Psychology, The Beckman Institute, 405 N Mathews Avenue, Urbana, IL 61801, USA
Physiol Behav 99:412-8. 2010..Future studies are needed to comprehensively establish neuroanatomical specificity in conditioned responses to drugs as compared to other reinforcers...
Acute effects of acamprosate and MPEP on ethanol Drinking-in-the-Dark in male C57BL/6J miceTripta Gupta
Department of Psychology, The Beckman Institute, University of Illinois at Urbana Champaign, Urbana, Illinois 61801, USA
Alcohol Clin Exp Res 32:1992-8. 2008..In DID, mice are offered intermittent, limited access to ethanol over a series of days during the dark phase that results in rapid drinking to intoxication in predisposed genotypes...
Hybrid C57BL/6J x FVB/NJ mice drink more alcohol than do C57BL/6J miceYuri A Blednov
Waggoner Center for Alcohol and Addictions Research, University of Texas, Austin, TX 78712 0159, USA
Alcohol Clin Exp Res 29:1949-58. 2005..No strain has been found to consume more ethanol than B6. In one of our laboratories (Texas), we noted a markedly greater intake of ethanol in an F1 hybrid of B6 and FVB/NJ (FVB) mice...
Evaluation of a simple model of ethanol drinking to intoxication in C57BL/6J miceJustin S Rhodes
Portland Alcohol Research Center, Department of Behavioral Neuroscience, Oregon Health and Science University, and VA Medical Center, Portland, Oregon 97239, USA
Physiol Behav 84:53-63. 2005..We discuss advantages of the model for high-throughput screening assays where the goal is to find other genotypes of mice that drink excessively, or to screen drugs for their efficacy in blocking excessive drinking...
Gene expression induced by drugs of abuseJustin S Rhodes
VA Medical Center, Portland, OR 97239, USA
Curr Opin Pharmacol 5:26-33. 2005..g. stress, altered body temperature or energy metabolism)...
Opioid-mediated pain sensitivity in mice bred for high voluntary wheel runningGuo Li
Department of Zoology, University of Wisconsin-Madison, Madison, WI 53706, USA
Physiol Behav 83:515-24. 2004..p.) decreased wheel running equally in High-Runner and C mice. Further studies will be required to determine whether other types of pain sensitivity have also failed to evolve in association with increased voluntary wheel running...
Patterns of brain activity associated with variation in voluntary wheel-running behaviorJustin S Rhodes
Department of Zoology, University of Wisconsin-Madison, 53706, USA
Behav Neurosci 117:1243-56. 2003..Results implicate specific brain regions in motivation to run and others in control of the intensity of the locomotor behavior itself...
