Research Topics
Genomes and GenesSpecies | Soo RheeSummaryAffiliation: University of Colorado Country: USA Publications
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Publications
Early concern and disregard for others as predictors of antisocial behaviorSoo Hyun Rhee
Institute for Behavioral Genetics, University of Colorado, Boulder, CO 80309 0345, USA
J Child Psychol Psychiatry 54:157-66. 2013..The present study tested the hypothesis that both concern for others and active disregard for others in distress in toddlers and young children predict antisocial behavior during middle childhood and adolescence...
Early childhood temperament and the covariation between internalizing and externalizing behavior in school-aged childrenSoo Hyun Rhee
Institute for Behavioral Genetics, University of Colorado, Boulder, Colorado 80309 0447, USA
Twin Res Hum Genet 10:33-44. 2007..A possible limitation of this study is that the covariation between temperament and behavior problems may be due to shared measurement variance, as parent ratings were used to assess both temperament and behavior problems...- The inclusion of measured covariates in the Neale and Kendler model fitting approachSoo Hyun Rhee
Institute for Behavioral Genetics, University of Colorado, Campus Box 447, Boulder, CO 80309, USA
Behav Genet 37:423-32. 2007..An example of 13 models examining the comorbidity between alcohol dependence and illicit drug dependence is presented... - Test of alternative hypotheses explaining the comorbidity between attention-deficit/hyperactivity disorder and conduct disorderSoo Hyun Rhee
Department of Psychology, University of Colorado, Boulder, CO 80309, USA
J Abnorm Child Psychol 36:29-40. 2008..The results suggest that correlated risk factors are a better explanation for the comorbidity between ADHD and CD than a third, independent ADHD+CD subtype... - Comorbidity between alcohol dependence and illicit drug dependence in adolescents with antisocial behavior and matched controlsSoo Hyun Rhee
Institute for Behavioral Genetics, Campus Box 447, University of Colorado, Boulder, CO 80309, USA
Drug Alcohol Depend 84:85-92. 2006..Discrepancies in results may reflect different analytical approaches or differences in the samples. Here, we examine the causes of comorbidity between alcohol dependence and illicit drug dependence in adolescents... - Testing hypotheses regarding the causes of comorbidity: examining the underlying deficits of comorbid disordersSoo Hyun Rhee
Department of Psychology, University of Colorado, Boulder, CO 80309, USA
J Abnorm Psychol 114:346-62. 2005..The ability to distinguish the correct model decreased as the sample size and the correlation between the underlying deficits and the symptom scores decreased, suggesting that the issue of power should be considered carefully... - Etiology of sex differences in the prevalence of ADHD: an examination of inattention and hyperactivity-impulsivitySoo Hyun Rhee
Department of Psychology and Institute for Behavioral Genetics, University of Colorado, Colorado 80309, USA
Am J Med Genet B Neuropsychiatr Genet 127:60-4. 2004..This evidence for the PMT model and against the CV model was found for both inattention and hyperactivity-impulsivity, but became weaker for hyperactivity-impulsivity as symptom severity increased... - The validity of analyses testing the etiology of comorbidity between two disorders: comparisons of disorder prevalences in familiesSoo Hyun Rhee
Department of Psychology, Institute for Behavioral Genetics, Campus Box 447, University of Colorado, Boulder, Colorado 80309, USA
Behav Genet 33:257-69. 2003.... - Genetic and environmental influences on antisocial behavior: a meta-analysis of twin and adoption studiesSoo Hyun Rhee
Department of Psychology, Emory University, USA
Psychol Bull 128:490-529. 2002.... - Genetic and environmental influences on substance initiation, use, and problem use in adolescentsSoo Hyun Rhee
Department of Psychology and the Institute for Behavioral Genetics, University of Colorado at Boulder, 90309, USA
Arch Gen Psychiatry 60:1256-64. 2003..We conducted a sibling/twin/adoption study of substance initiation, use, and problem use, estimating the relative contribution of genetic and environmental influences on these phenotypes in adolescents... - The validity of the Neale and Kendler model-fitting approach in examining the etiology of comorbiditySoo Hyun Rhee
Institute for Behavioral Genetics, University of Colorado, Boulder, Colorado 80309, USA
Behav Genet 34:251-65. 2004..As suggested by Neale and Kendler, the model-fitting approach can be applied to both unselected and selected data and to both twin and family data... - The validity of analyses testing the etiology of comorbidity between two disorders: a review of family studiesSoo Hyun Rhee
Institute for Behavioral Genetics, University of Colorado, Boulder 80309, USA
J Child Psychol Psychiatry 44:612-36. 2003..Unfortunately, the conclusions of family studies using these two methods have been conflicting. In the present study, we examined the validity of family prevalence analyses in testing alternative comorbidity models... - The neuronal nicotinic receptor subunit genes (CHRNA6 and CHRNB3) are associated with subjective responses to tobaccoJoanna S Zeiger
Institute for Behavioral Genetics, University of Colorado, Boulder, CO 80309, USA
Hum Mol Genet 17:724-34. 2008..These results indicate that early subjective response to nicotine may be a valuable endophenotype for genetic studies aimed at uncovering genes contributing to nicotine use and addiction... 
Common genetic and environmental influences on major depressive disorder and conduct disorderAnjali Subbarao
Department of Psychology, University of Colorado, Boulder, CO, USA
J Abnorm Child Psychol 36:433-44. 2008..Our results suggest that some genetic factors will increase an individual's vulnerability to both MDD and CD in adolescence...- Examining the heritability of a laboratory-based smoking endophenotype: initial results from an experimental twin studyLara A Ray
Department of Psychology and Institute for Behavioral Genetics, University of Colorado, Boulder, Colorado, United States of America
Twin Res Hum Genet 10:546-53. 2007..To the best of our knowledge, this is the first study to examine the genetic basis of a laboratory smoking endophenotype, in this case tension reduction after smoking. Implications for genetic association studies are discussed... - Analyzing comorbidityBruce F Pennington
Department of Psychology, University of Denver, Denver, CO 80208, USA
Adv Child Dev Behav 33:263-304. 2005 - The CHRNA5/A3/B4 gene cluster variability as an important determinant of early alcohol and tobacco initiation in young adultsIsabel R Schlaepfer
Institute for Behavioral Genetics, Department of Integrative Physiology, University of Colorado, Boulder, CO 80309, USA
Biol Psychiatry 63:1039-46. 2008..Significant results were then replicated in a separate adult population-representative sample... - Case-control and within-family tests for an association between conduct disorder and DAT1R Jay Schulz-Heik
Institute for Behavioral Genetics, Department of Psychology, University of Colorado, Boulder 80309, USA
Psychiatr Genet 18:17-24. 2008..Evidence suggests that a variable number tandem repeat polymorphism of the dopamine transporter (DAT1) gene may be associated with externalizing behavior in children... - Association of candidate genes with antisocial drug dependence in adolescentsRobin P Corley
Institute for Behavioral Genetics, University of Colorado, 447 UCB, Boulder, CO 80309, USA
Drug Alcohol Depend 96:90-8. 2008..The custom-designed SNP chip served as an effective and flexible platform for rapid interrogation of a large number of plausible candidate genes... - Perceived peer delinquency and the genetic predisposition for substance dependence vulnerabilityTanya M M Button
Institute for Behavioral Genetics, Campus Box 447, University of Colorado, Boulder, CO 80309, United States
Drug Alcohol Depend 100:1-8. 2009..The magnitudes of both shared and non-shared environmental influences were negligible among those who perceived their peers to be least delinquent and were greater among those with higher levels of perceived peers' delinquency... - The relation between sluggish cognitive tempo and DSM-IV ADHDChristie A Hartman
Institute for Behavioral Genetics and Department of Psychology, University of Colorado at Boulder, Boulder, Colorado 80309 0447, USA
J Abnorm Child Psychol 32:491-503. 2004..These results suggest that SCT is an internally consistent construct that is significantly associated with DSM-IV inattention... - Investigation of genetically mediated child effects on maltreatmentR Jay Schulz-Heik
Department of Psychology, University of Colorado, Boulder, CO, USA
Behav Genet 39:265-76. 2009.... - The association between cannabinoid receptor 1 gene (CNR1) and cannabis dependence symptoms in adolescents and young adultsChristie A Hartman
School of Medicine, University of Colorado at Denver, PO Box 6508, Mail Stop F478, Aurora, CO 80045, USA
Drug Alcohol Depend 104:11-6. 2009..This study examined the genetic association between variation in the cannabinoid receptor 1 (CNR1) gene and cannabis dependence symptoms... - The association between conduct problems and maltreatment: testing genetic and environmental mediationR Jay Schulz-Heik
Department of Psychology, University of Colorado, UCB 345, Boulder, CO 80309, USA
Behav Genet 40:338-48. 2010..Results were more consistent with the hypothesis that parents respond to children's genetically-influenced conduct problems by maltreating them than the hypothesis that maltreatment causes conduct problems... - Subjective effects to marijuana associated with marijuana use in community and clinical subjectsJoanna S Zeiger
Institute for Behavioral Genetics, University of Colorado, 447 UCB, Boulder, CO 80309, United States
Drug Alcohol Depend 109:161-6. 2010..e. subjective effects). We have examined subjective effects in adolescent, young adult community, and clinical populations to determine how patterns of use may be predicted by an individual's subjective experiences with the drug... - The etiology of stability and change in religious values and religious attendanceTanya M M Button
Institute for Behavioral Genetics, University of Colorado at Boulder, 1480 30th Street, Boulder, CO 80309 0447, USA
Behav Genet 41:201-10. 2011.... - Bivariate analysis of disordered eating characteristics in adolescence and young adulthoodMelissa A Munn
Department of Psychology and Neuroscience, University of Colorado, Boulder, Colorado, USA
Int J Eat Disord 43:751-61. 2010..We examined the etiology of two disordered eating characteristics... - Delinquent peer affiliation and conduct problems: A twin studyTanya M M Button
Institute for Behavioral Genetics, University of Colorado, Boulder, CO 80309, USA
J Abnorm Psychol 116:554-64. 2007..The magnitude of the genetic variance of conduct problems was contextually dependent on levels of delinquent peer affiliation and was greater at higher levels of delinquent peer affiliation... - Genetic and environmental vulnerabilities underlying adolescent substance use and problem use: general or specific?Susan E Young
Institute for Behavioral Genetics, University of Colorado, 447 UCB, Boulder, CO 80303, USA
Behav Genet 36:603-15. 2006..Our results suggest that tobacco, alcohol, and marijuana problem use are mediated by common genetic influences, but shared environmental influences may be more substance-specific for problem use... - Genetic and environmental influences on conduct disorder: symptom, domain and full-scale analysesHeather L Gelhorn
Institute for Behavioral Genetics, University of Colorado, Boulder, CO 80309 0447, USA
J Child Psychol Psychiatry 46:580-91. 2005.... - A genome-wide search for quantitative trait Loci that influence antisocial drug dependence in adolescenceMichael C Stallings
Institute for Behavioral Genetics and Department of Molecular, Cellular, and Developmental Biology, University of Colorado, Boulder, 80309 0444, USA
Arch Gen Psychiatry 62:1042-51. 2005..Previously we reported 2 chromosomal regions (3q24-3q25 and 9q34) likely to contain genes that influence substance dependence vulnerability (DV) in adolescence... - Genetic and environmental contributions to common psychopathologies of childhood and adolescence: a study of twins and their siblingsMarissa A Ehringer
Institute for Behavioral Genetics, University of Colorado at Boulder, 80309, USA
J Abnorm Child Psychol 34:1-17. 2006..We found evidence for both genetic and non-shared environmental influences for all disorders. Shared environmental influences also seem to be important for MDD and lifetime GAD... - The moderating effects of religiosity on the genetic and environmental determinants of smoking initiationDavid S Timberlake
Institute for Behavioral Genetics, University of Colorado, Boulder, CO 80309 0447, USA
Nicotine Tob Res 8:123-33. 2006..Although all three measures of religiosity were associated with lower rates of smoking initiation, only self-rated religiousness moderated genetic influences on the liability for smoking... - Examination of the causes of covariation between conduct disorder symptoms and vulnerability to drug dependenceTanya M M Button
Institute for Behavioral Genetics, University of Colorado, Boulder, Colorado 80309 0447, USA
Twin Res Hum Genet 9:38-45. 2006..Therefore, there appears to be pleiotropic genetic influence on CD symptoms and dependence vulnerability... - Common and specific genetic influences on aggressive and nonaggressive conduct disorder domainsHeather Gelhorn
Institute for Behavioral Genetics, University of Colorado, Boulder, 80309, USA
J Am Acad Child Adolesc Psychiatry 45:570-7. 2006..To explore the genetic and environmental influences on DSM-IV conduct disorder (CD) aggressive and nonaggressive subscales, taking into account age and sex differences... - The role of conduct disorder in explaining the comorbidity between alcohol and illicit drug dependence in adolescenceTanya M M Button
Institute for Behavioral Genetics, Campus Box 447, University of Colorado, Boulder, CO 80309, USA
Drug Alcohol Depend 87:46-53. 2007..This paper describes the result of an investigation of the extent to which comorbid alcohol and illicit drug dependence in adolescents are explained by etiological factors in common with conduct disorder... - A genome-wide search for quantitative trait loci influencing substance dependence vulnerability in adolescenceMichael C Stallings
Institute for Behavioral Genetics, University of Colorado, Campus Box 447, Boulder, CO 80309 0447, USA
Drug Alcohol Depend 70:295-307. 2003..2. Multipoint mapping corroborated two locations and provided preliminary evidence for linkage to regions on chromosome 3q24-25 (near markers D3S1279 and D3S1614) and chromosome 9q34 (near markers D9S1826 and D9S1838)... - Association of the neuronal nicotinic receptor beta2 subunit gene (CHRNB2) with subjective responses to alcohol and nicotineMarissa A Ehringer
Institute for Behavioral Genetics, University of Colorado, Boulder, Colorado 80309, USA
Am J Med Genet B Neuropsychiatr Genet 144:596-604. 2007..This study provides the first evidence for association between the CHRNB2 gene and nicotine- and alcohol-related phenotypes, and suggests that polymorphisms in CHRNB2 may be important in mediating early responses to nicotine and alcohol... - The human protein kinase C gamma gene (PRKCG) as a susceptibility locus for behavioral disinhibitionIsabel R Schlaepfer
Institute for Behavioral Genetics, University of Colorado, Boulder, USA, and Department of Integrative Physiology, University of Colorado, Boulder, CO 80309, USA
Addict Biol 12:200-9. 2007..This study provides the first exploration of the PRKCG gene and its association with behavioral disinhibition and warrants further study in other larger population samples... - Item response theory analysis of DSM-IV cannabis abuse and dependence criteria in adolescentsChristie A Hartman
School of Medicine at the University of Colorado Health Sciences Center, 4200 East 9th Avenue, Denver, CO 80262, USA
J Am Acad Child Adolesc Psychiatry 47:165-73. 2008..different levels of severity of substance involvement, to what degree do each of the 11 abuse and dependence criteria assess adolescent cannabis problems, and do the DSM-IV items function similarly across different adolescent populations?.. - College attendance and its effect on drinking behaviors in a longitudinal study of adolescentsDavid S Timberlake
Institute for Behavioral Genetics, University of Colorado, Boulder, Colorado, USA
Alcohol Clin Exp Res 31:1020-30. 2007..We first tested for changes in alcohol consumption in adolescents who did and did not subsequently attend college, and then tested for variation of the genetic and environmental determinants of drinking in these 2 groups... - Cannabis receptor haplotype associated with fewer cannabis dependence symptoms in adolescentsChristian J Hopfer
Department of Psychiatry, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
Am J Med Genet B Neuropsychiatr Genet 141:895-901. 2006..Our findings provide evidence suggesting that a common CNR1 haplotype is associated with developing fewer cannabis dependence symptoms among adolescents who have experimented with cannabis... - A genome-wide scan for loci influencing adolescent cannabis dependence symptoms: evidence for linkage on chromosomes 3 and 9Christian J Hopfer
Division of Substance Dependence, University of Colorado School of Medicine, 4200 East Ninth Avenue, Denver, CO 80262, USA
Drug Alcohol Depend 89:34-41. 2007..Genetic risk factors account for part of the variation in the development of cannabis dependence symptoms; however, no linkage studies have been performed for cannabis dependence symptoms. This study aimed to identify such loci... - Comorbidity of depression with levels of smoking: an exploration of the shared familial risk hypothesisEric O Johnson
Department of Psychiatry, Henry Ford Health Sciences Center, Detroit, MI 48202, USA
Nicotine Tob Res 6:1029-38. 2004..The conflicting findings of the studies that have examined the relationship between smoking and depression may be attributable to differences in definition of the disorders and the methods used to analyze them...
Research Grants
- Causes of Comorbidity:Substance Use Disorder, ADHD & CDSoo Rhee; Fiscal Year: 2005....
- Testing a Developmental Model of Conduct ProblemsSoo Rhee; Fiscal Year: 2007....
- Testing a Developmental Model of Conduct ProblemsSoo Rhee; Fiscal Year: 2009....
- Testing a Developmental Model of Conduct ProblemsSOO H RHEE; Fiscal Year: 2010....