M A Reynolds

Summary

Affiliation: University of Maryland
Country: USA

Publications

  1. ncbi MDM2+/CDK4+/p53+ oral liposarcoma: case report and review of the literature
    N G Nikitakis
    Oral and Maxi ofacial Pathology, Dental School, University of Maryland, Baltimore 21201 1586, USA
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 92:194-201. 2001
  2. ncbi The role of apoptosis in oral disease: mechanisms; aberrations in neoplastic, autoimmune, infectious, hematologic, and developmental diseases; and therapeutic opportunities
    Nikolaos G Nikitakis
    Department of Diagnostic Sciences and Pathology, University of Maryland, Baltimore 21201, USA
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 97:476-90. 2004
  3. ncbi Targeting the STAT pathway in head and neck cancer: recent advances and future prospects
    N G Nikitakis
    Department of Diagnostic Sciences and Pathology, Dental School, University of Maryland, Baltimore, MD 21201, USA
    Curr Cancer Drug Targets 4:637-51. 2004
  4. ncbi Immunohistochemical expression of cytokeratins 7 and 20 in malignant salivary gland tumors
    Nikolaos G Nikitakis
    Department of Diagnostic Sciences and Pathology, University of Maryland, Baltimore, MD 21201, USA
    Mod Pathol 17:407-15. 2004
  5. ncbi Malignant peripheral primitive neuroectodermal tumor-peripheral neuroepithelioma of the head and neck: a clinicopathologic study of five cases and review of the literature
    Nikolaos G Nikitakis
    Department of Diagnostic Sciences and Pathology, Dental School, University of Maryland, Baltimore, 666 W Baltimore Street, Room 4 C 02, Baltimore, Maryland 21201 1586, USA
    Head Neck 25:488-98. 2003
  6. ncbi MDM2 and CDK4 expression in carcinosarcoma of the esophagus: comparison with squamous cell carcinoma and review of the literature
    Nikolaos G Nikitakis
    Department of Diagnostic Sciences and Pathology, Dental School, University of Maryland, Baltimore, Maryland 21201 1586, USA
    Exp Mol Pathol 73:198-208. 2002
  7. ncbi 15-PGJ2, but not thiazolidinediones, inhibits cell growth, induces apoptosis, and causes downregulation of Stat3 in human oral SCCa cells
    N G Nikitakis
    Department of Diagnostic Sciences and Pathology, University of Maryland, 666 W Baltimore Street, Room 4 C 02, Baltimore, MD 21201, USA
    Br J Cancer 87:1396-403. 2002
  8. ncbi Oral leiomyosarcoma: review of the literature and report of two cases with assessment of the prognostic and diagnostic significance of immunohistochemical and molecular markers
    Nikolaos G Nikitakis
    Department of Oral and Maxillofacial Pathology, Dental School, University of Maryland, Baltimore 666 W Baltimore Street, Room 4 C 02, Baltimore, MD 21201 1586, USA
    Oral Oncol 38:201-8. 2002
  9. ncbi PPARgamma-mediated antineoplastic effect of NSAID sulindac on human oral squamous carcinoma cells
    Nikolaos G Nikitakis
    Department of Diagnostic Sciences and Pathology, University of Maryland, Baltimore, MD 21201 1586, USA
    Int J Cancer 98:817-23. 2002
  10. ncbi The effects of a calorie-reduced diet on periodontal inflammation and disease in a non-human primate model
    Grishondra L Branch-Mays
    Department of Periodontics, University of Maryland Dental School, Baltimore, MD, USA
    J Periodontol 79:1184-91. 2008

Collaborators

Detail Information

Publications36

  1. ncbi MDM2+/CDK4+/p53+ oral liposarcoma: case report and review of the literature
    N G Nikitakis
    Oral and Maxi ofacial Pathology, Dental School, University of Maryland, Baltimore 21201 1586, USA
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 92:194-201. 2001
    ..Possible implications of molecular and cytogenetic analysis for unraveling the pathogenesis and determining the prognosis of liposarcoma are discussed...
  2. ncbi The role of apoptosis in oral disease: mechanisms; aberrations in neoplastic, autoimmune, infectious, hematologic, and developmental diseases; and therapeutic opportunities
    Nikolaos G Nikitakis
    Department of Diagnostic Sciences and Pathology, University of Maryland, Baltimore 21201, USA
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 97:476-90. 2004
    ....
  3. ncbi Targeting the STAT pathway in head and neck cancer: recent advances and future prospects
    N G Nikitakis
    Department of Diagnostic Sciences and Pathology, Dental School, University of Maryland, Baltimore, MD 21201, USA
    Curr Cancer Drug Targets 4:637-51. 2004
    ....
  4. ncbi Immunohistochemical expression of cytokeratins 7 and 20 in malignant salivary gland tumors
    Nikolaos G Nikitakis
    Department of Diagnostic Sciences and Pathology, University of Maryland, Baltimore, MD 21201, USA
    Mod Pathol 17:407-15. 2004
    ....
  5. ncbi Malignant peripheral primitive neuroectodermal tumor-peripheral neuroepithelioma of the head and neck: a clinicopathologic study of five cases and review of the literature
    Nikolaos G Nikitakis
    Department of Diagnostic Sciences and Pathology, Dental School, University of Maryland, Baltimore, 666 W Baltimore Street, Room 4 C 02, Baltimore, Maryland 21201 1586, USA
    Head Neck 25:488-98. 2003
    ..Here, we focus on one particular member of the PNET family, the malignant peripheral PNET (pPNET) or peripheral neuroepithelioma of head and neck...
  6. ncbi MDM2 and CDK4 expression in carcinosarcoma of the esophagus: comparison with squamous cell carcinoma and review of the literature
    Nikolaos G Nikitakis
    Department of Diagnostic Sciences and Pathology, Dental School, University of Maryland, Baltimore, Maryland 21201 1586, USA
    Exp Mol Pathol 73:198-208. 2002
    ..These differences in the MDM2 and CDK4 immunohistochemical profile between carcinosarcomas and carcinomas of the esophagus may assist in their differential diagnosis...
  7. ncbi 15-PGJ2, but not thiazolidinediones, inhibits cell growth, induces apoptosis, and causes downregulation of Stat3 in human oral SCCa cells
    N G Nikitakis
    Department of Diagnostic Sciences and Pathology, University of Maryland, 666 W Baltimore Street, Room 4 C 02, Baltimore, MD 21201, USA
    Br J Cancer 87:1396-403. 2002
    ....
  8. ncbi Oral leiomyosarcoma: review of the literature and report of two cases with assessment of the prognostic and diagnostic significance of immunohistochemical and molecular markers
    Nikolaos G Nikitakis
    Department of Oral and Maxillofacial Pathology, Dental School, University of Maryland, Baltimore 666 W Baltimore Street, Room 4 C 02, Baltimore, MD 21201 1586, USA
    Oral Oncol 38:201-8. 2002
    ..The literature, pertinent to oral leiomyosarcoma and to molecular analysis of smooth muscle tumors, is reviewed...
  9. ncbi PPARgamma-mediated antineoplastic effect of NSAID sulindac on human oral squamous carcinoma cells
    Nikolaos G Nikitakis
    Department of Diagnostic Sciences and Pathology, University of Maryland, Baltimore, MD 21201 1586, USA
    Int J Cancer 98:817-23. 2002
    ..We suggest that upregulation of PPARgamma expression and activation may be, at least partially, responsible for sulindac's antiproliferative effect...
  10. ncbi The effects of a calorie-reduced diet on periodontal inflammation and disease in a non-human primate model
    Grishondra L Branch-Mays
    Department of Periodontics, University of Maryland Dental School, Baltimore, MD, USA
    J Periodontol 79:1184-91. 2008
    ..The purpose of this study was to evaluate the clinical effects of a long-term calorie-restriction (CR) diet on periodontitis in an animal model of periodontitis...
  11. ncbi Factors influencing the outcome of regenerative therapy in mandibular Class II furcations: Part I
    Gerald M Bowers
    University of Maryland Dental School, Department of Periodontics, Baltimore, MD 21201, USA
    J Periodontol 74:1255-68. 2003
    ..Also, 15 out of 22 (68%) of all residual defects were reduced to Class I and only seven (8%) failed to improve, demonstrating that successful clinical resolution of advanced defects remains an attainable goal...
  12. ncbi A retrospective case series comparing the use of demineralized freeze-dried bone allograft and freeze-dried bone allograft combined with enamel matrix derivative for the treatment of advanced osseous lesions
    Paul S Rosen
    Department of Periodontics, Baltimore College of Dental Surgery, University of Maryland, Baltimore, USA
    J Periodontol 73:942-9. 2002
    ..Larger prospective controlled clinical trials are needed to determine if differences exist in the relative efficacy of DFDBA versus FDBA in combination with EMD...
  13. ncbi Regeneration of periodontal tissue: bone replacement grafts
    Mark A Reynolds
    Department of Periodontics, Dental School, University of Maryland, 650 West Baltimore Street, Baltimore, MD 21201, USA
    Dent Clin North Am 54:55-71. 2010
    ..Emphasis is placed on the clinical and biologic goals of periodontal regeneration as well as evidence-based treatment outcomes...
  14. ncbi Calcium sulfate-carboxymethylcellulose bone graft binder: Histologic and morphometric evaluation in a critical size defect
    Mark A Reynolds
    Department of Periodontics, University of Maryland, Dental School, Baltimore, Maryland, USA
    J Biomed Mater Res B Appl Biomater 83:451-8. 2007
    ..Thus, CMC was found to improve the handling characteristics of CS and, when used in conjunction with DBM, supported comparable levels bone formation and patterns of binder/scaffold resorption as CS and DBM in a calvarial defect model...
  15. ncbi Non-steroidal anti-inflammatory drug (NSAID)-derived poly(anhydride-esters) in bone and periodontal regeneration
    Mark A Reynolds
    Department of Periodontics, University of Maryland Dental School, Baltimore, MD 21201, USA
    Curr Drug Deliv 4:233-9. 2007
    ....
  16. ncbi Predictability of clinical outcomes following regenerative therapy in intrabony defects
    Mary Elizabeth Aichelmann-Reidy
    Department of Periodontics, Dental School, University of Maryland, 650 West Baltimore Street, Baltimore, MD 21201, USA
    J Periodontol 79:387-93. 2008
    ..For comparative purposes, a similar analysis was performed evaluating the consistency of clinical outcomes with other (non-DBM) bone replacement graft (BRG) materials relative to OFD alone...
  17. ncbi Effects of caloric restriction on inflammatory periodontal disease
    Mark A Reynolds
    Department of Periodontics, University of Maryland, Dental School, Baltimore, Maryland, USA
    Nutrition 25:88-97. 2009
    ..The purpose of this study was to examine the effects of long-term CR on naturally occurring chronic inflammatory periodontal disease in a nonhuman primate model...
  18. ncbi Estrogen suppression induces papillary gingival overgrowth in pregnant baboons
    Mark A Reynolds
    Department of Periodontics, University of Maryland, Dental School, Baltimore, MD 21201, USA
    J Periodontol 75:693-701. 2004
    ..Currently, few experimental animal models similar to humans are available to examine regulatory pathways involving sex steroids and the periodontium...
  19. ncbi Clinical evaluation of calcium sulfate in combination with demineralized freeze-dried bone allograft for the treatment of human intraosseous defects
    Mary E Aichelmann-Reidy
    Department of Periodontics, University of Maryland, Baltimore, MD 21201, USA
    J Periodontol 75:340-7. 2004
    ....
  20. ncbi The efficacy of bone replacement grafts in the treatment of periodontal osseous defects. A systematic review
    Mark A Reynolds
    Department of Periodontics, Baltimore College of Dental Surgery, University of Maryland, Baltimore, Maryland, USA
    Ann Periodontol 8:227-65. 2003
    ....
  21. ncbi Evidence for up-regulated central nociceptive processing in patients with masticatory myofascial pain
    Eleni Sarlani
    Department of Biomedical Sciences, Research Center for Neuroendocrine Influences on Pain, Brotman Facial Pain Center, University of Maryland, Baltimore, MD 21201, USA
    J Orofac Pain 18:41-55. 2004
    ..The aim of this study was to test this theory by assessing differences, between myalgic TMD patients and pain-free controls, in temporal summation of mechanically evoked pain and aftersensations following repetitive noxious stimulation...
  22. ncbi Recurrent idiopathic gingival enlargement in an olive baboon (Papio anubis)
    Krishnan Kolappaswamy
    Program of Comparative Medicine, Department of Pathology, University of Maryland, Baltimore, Maryland, USA
    J Am Assoc Lab Anim Sci 49:860-2. 2010
    ..Clinical and histopathologic findings confirmed a diagnosis of idiopathic gingival enlargement...
  23. ncbi Sex differences in temporal summation of pain and aftersensations following repetitive noxious mechanical stimulation
    Eleni Sarlani
    University of Maryland Dental School, Baltimore, MD, USA
    Pain 109:115-23. 2004
    ....
  24. ncbi Histopathologic findings in bone from edentulous alveolar ridges: a role in osteonecrosis of the jaws?
    James D Kassolis
    Department of Periodontics, University of Maryland, Dental School, Baltimore, MD, USA
    Bone 47:127-30. 2010
    ..Regions of necrotic bone and subclinical infection may contribute to the development of untoward clinical events, such BONJ and early implant failure...
  25. ncbi Immunohistochemical expression of angiogenesis-related markers in oral squamous cell carcinomas with multiple metastatic lymph nodes
    Nikolaos G Nikitakis
    Dept of Diagnostic Sciences and Pathology, Dental School, University of Maryland, 666 W Baltimore St, Room 4-C-02, Baltimore, MD 21201-1586, USA
    Am J Clin Pathol 119:574-86. 2003
    ....
  26. ncbi Association of periodontitis and metabolic syndrome in the Baltimore Longitudinal Study of Aging
    Mark J Nesbitt
    Longitudinal Studies Section, Clinical Research Branch, National Institute on Aging, Baltimore, MD, USA
    Aging Clin Exp Res 22:238-42. 2010
    ..This study examines the association of periodontitis with MetS with and without consideration of systemic inflammatory status...
  27. ncbi Allogeneic bone onlay grafts for alveolar ridge augmentation: a systematic review
    Jonathan Waasdorp
    Department of Periodontics, University of Maryland, Dental School, Baltimore, Maryland 21201, USA
    Int J Oral Maxillofac Implants 25:525-31. 2010
    ..This systematic review examines the published findings on the clinical effectiveness and predictability of allogeneic bone blocks for the correction of alveolar ridge deformities to support dental implant placement in humans...
  28. ncbi Formation of mucogingival defects associated with intraoral and perioral piercing: case reports
    John K Brooks
    Department of Diagnostic Sciences and Pathology, Dental School, University of Maryland, Baltimore 21201 1586, USA
    J Am Dent Assoc 134:837-43. 2003
    ..They also present a literature review of other adverse dental and medical consequences attributed to oral piercing...
  29. ncbi Surgical salvage for local and regional recurrence in oral cancer
    Robert A Ord
    Department of Oral and Maxillofacial Surgery, University of Maryland, Greenbaum Cancer Center, Baltimore, MD 21201-1754, USA
    J Oral Maxillofac Surg 64:1409-14. 2006
    ..Salvage was best achieved with surgery or surgery + adjuvant therapy, and patients recurring within 6 months had a worse survival. Patients with locoregional recurrence or treated with RT +/- chemotherapy alone have negligible survival...
  30. ncbi The segmental osteotomy in the management of malposed implants: a case report and literature review
    James D Kassolis
    Department of Periodontics, University of Maryland, Dental School, Baltimore, MD, USA
    J Periodontol 74:529-36. 2003
    ..CONCLUSION: The segmental osteotomy may provide an alternative treatment to the removal of severely malposed implants or their compromised prosthetic restoration...
  31. ncbi Biomarkers predictive of lymph node metastases in oral squamous cell carcinoma
    Marcio Ajudarte Lopes
    Oral Diagnosis, Faculty of Odontology of Piracicaba, UNICAMP, Sao Paulo, Brazil
    J Oral Maxillofac Surg 60:142-7; discussion 147-8. 2002
    ..The aim of this study was to attempt to define a trend for predictive histopathologic and/or molecular biomarkers in the development of nodal metastasis by analyzing 2 clinically extreme groups...
  32. ncbi The era of biologics and reparative medicine: a pivotal clinical trial of platelet-derived growth factor for periodontal regeneration
    Mark A Reynolds
    J Periodontol 76:2330-2. 2005
  33. ncbi Evaluation of the adjunctive benefits of platelet-rich plasma in subantral sinus augmentation
    James D Kassolis
    Department of Periodontics, University of Maryland Dental School, Timonium, MD, USA
    J Craniofac Surg 16:280-7. 2005
    ..Future research is needed to determine the clinical significance and the cost- and risk-benefit considerations of the approach...
  34. ncbi Carcinosarcoma of the maxilla in a squirrel monkey (Saimiri sciureus)
    Niki M Moutsopoulos
    Department of Periodontics, University of Maryland Dental School, 666 W Baltimore St, Baltimore, Maryland 21201, USA
    Comp Med 54:333-6. 2004
    ..The histolopathologic findings, the pattern of metastasis, and the clinical progression closely resembled those of carcinosarcoma involving salivary glands in humans...
  35. ncbi Molecular markers for prostate cancer
    Mark A Reynolds
    Gen Probe Incorporated, 10210 Genetic Center Drive, San Diego, CA 92121, USA
    Cancer Lett 249:5-13. 2007
    ..The goal of current research is to apply genomic assays to noninvasive specimens such as blood and urine. Progress in this area is the subject of this review...
  36. ncbi Minocycline-associated intra-oral soft-tissue pigmentation: clinicopathologic correlations and review
    Vincent N LaPorta
    Department of Periodontics, Dental School, University of Maryland, 666 W. Baltimore Street, Baltimore, MD 21201, USA
    J Clin Periodontol 32:119-22. 2005
    ..A brief review of the literature is presented to help understand this uncommon finding that should be included in the differential diagnosis of spontaneous discoloration of intra-oral soft tissues...