Research Topics
| V I ReusSummaryAffiliation: University of California Country: USA Publications
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Detail Information
Publications
Antiglucocorticoid treatments in psychiatryV I Reus
University of California, San Francisco, School of Medicine, Department of Psychiatry 94143 0984, USA
Psychoneuroendocrinology 22:S121-4. 1997..The data thus far suggest that antiglucocorticoid drug treatment may be useful in certain subgroups of depressed patients and may offer a theoretical rationale for alternative drug design...- Antiglucocorticoid drugs in the treatment of depressionV I Reus
Department of Psychiatry, Center on Neurobiology and Behavior, University of California, San Francisco, School of Medicine, 401 Parnassus Avenue, Box F 0984, CA 94143 0984, USA
Expert Opin Investig Drugs 10:1789-96. 2001.... - Mood management and nicotine gum in smoking treatment: a therapeutic contact and placebo-controlled studyS M Hall
Department of Psychology, University of California, San Francisco, USA
J Consult Clin Psychol 64:1003-9. 1996..History-positive smokers may be best treated by interventions providing additional support and contact, independent of therapeutic content... - Double-blind treatment of major depression with dehydroepiandrosteroneO M Wolkowitz
Department of Psychiatry, University of California Medical Center, San Francisco, USA
Am J Psychiatry 156:646-9. 1999..This study was designed to assess possible antidepressant effects of dehydroepiandrosterone (DHEA), an abundant adrenocortical hormone in humans... - Treatment of depression with antiglucocorticoid drugsO M Wolkowitz
Department of Psychiatry, University of California, San Francisco, School of Medicine 94143 0984, USA
Psychosom Med 61:698-711. 1999..The theoretical and empirical rationales for the potential therapeutic use of antiglucocorticoid agents in the treatment of depression are reviewed... - Stress hormone-related psychopathology: pathophysiological and treatment implicationsO M Wolkowitz
Department of Psychiatry, University of California, School of Medicine, San Francisco, USA
World J Biol Psychiatry 2:115-43. 2001..We then review certain clinical manifestations of such hormonal imbalances and discuss pharmacological and behavioural treatment strategies aimed at normalizing hormonal output and lessening psychiatric and physical pathology... 
Resting leukocyte telomerase activity is elevated in major depression and predicts treatment responseO M Wolkowitz
Department of Psychiatry, School of Medicine, University of California, San Francisco UCSF, San Francisco, CA 94143 0984, USA
Mol Psychiatry 17:164-72. 2012..PBMC telomerase activity might reflect a novel aspect of depressive pathophysiology and might represent a novel biomarker of antidepressant responsiveness...
Immunogenicity and smoking-cessation outcomes for a novel nicotine immunotherapeuticD K Hatsukami
Department of Psychiatry, University of Minnesota Tobacco Use Programs, Minneapolis, Minnesota, USA
Clin Pharmacol Ther 89:392-9. 2011..Its further development as a treatment for nicotine dependence is therefore justified...- Movement disorder, memory, psychiatric symptoms and serum DHEA levels in schizophrenic and schizoaffective patientsD S Harris
Department of Psychiatry, Box CPR 0984, University of California, San Francisco Medical Center, 401 Parnassus Ave, San Francisco, CA 94143 0984, USA
World J Biol Psychiatry 2:99-102. 2001.... - Cortisol levels predict cognitive impairment induced by electroconvulsive therapyT C Neylan
Department of Psychiatry, University of California, San Francisco, CA 94121, USA
Biol Psychiatry 50:331-6. 2001.... - Cultural influences on diagnosis and perception of Tourette syndrome in Costa RicaC A Mathews
Department of Psychiatry, University of California at San Francisco, 401 Parnassus Avenue, Box NGL 0984, San Francisco, CA 94143, USA
J Am Acad Child Adolesc Psychiatry 40:456-63. 2001..This study examines the phenomenology and presentation of TS in Costa Rica... - Glucocorticoid medication, memory and steroid psychosis in medical illnessO M Wolkowitz
Department of Psychiatry, University of California Medical Center San Francisco 94143, USA
Ann N Y Acad Sci 823:81-96. 1997.... - DHEA treatment of Alzheimer's disease: a randomized, double-blind, placebo-controlled studyO M Wolkowitz
Department of Psychiatry, Center for Neurobiology and Psychiatry, University of California San Francisco UCSF School of Medicine, USA
Neurology 60:1071-6. 2003..To compare the efficacy and tolerability of dehydroepiandrosterone (DHEA) vs placebo in AD... - Assortative mating in the affective disorders: a systematic review and meta-analysisC A Mathews
Department of Psychiatry, University of California at San Francisco, 94143, USA
Compr Psychiatry 42:257-62. 2001..These results support the previously reported findings, and may have important implications for genetic studies... - Development of major depression after treatment for smoking cessationJ Y Tsoh
Department of Psychiatry, University of California, San Francisco 94143, USA
Am J Psychiatry 157:368-74. 2000..Case studies suggest cigarette abstinence may precipitate a major depressive episode. This study examined the incidence and predictors of major depression in the 12 months after treatment for smoking cessation... - Extended nortriptyline and psychological treatment for cigarette smokingSharon M Hall
University of California San Francisco, 401 Parnassus Ave, Box 0984, San Francisco, CA 94143 0984, USA
Am J Psychiatry 161:2100-7. 2004..Using a chronic disease model of smoking, the authors undertook a study to determine the effects of long-term antidepressant and psychological treatment... - Repeated psychological stress testing in stimulant-dependent patientsDebra S Harris
Drug Dependence Research Center, Langley Porter Psychiatric Institute, Department of Psychiatry, University of California, San Francisco, CA, USA
Prog Neuropsychopharmacol Biol Psychiatry 29:669-77. 2005..Although less convincing because of the heterogeneity of the subjects, they also suggest that HPA axis responsivity is not clearly linked to acute stress-induced stimulant craving or affective response... - Cost-effectiveness of bupropion, nortriptyline, and psychological intervention in smoking cessationSharon M Hall
Department of Psychiatry, University of California, San Francisco, 94143, USA
J Behav Health Serv Res 32:381-92. 2005..Prospective investigations of the cost and cost-effectiveness of psychological and pharmacological intervention, using adequate sample sizes, are warranted... - Association between maternal smoking and increased symptom severity in Tourette's syndromeCarol A Mathews
Department of Psychiatry, University of California San Diego, La Jolla, CA, and the Department of Psychiatry, North Shore University Hospital New York University School of Medicine, Manhasset, NY, USA
Am J Psychiatry 163:1066-73. 2006.... - Older versus younger treatment-seeking smokers: differences in smoking behavior, drug and alcohol use, and psychosocial and physical functioningSharon M Hall
University of California, San Francisco, San Francisco, CA 94143 0984, USA
Nicotine Tob Res 10:463-70. 2008..Implications for the assessment and treatment of older adults are discussed... - Heritability and clinical features of multigenerational families with obsessive-compulsive disorder and hoardingCarol A Mathews
Department of Psychiatry, University of California, San Francisco, San Francisco, California 94143 0984, USA
Am J Med Genet B Neuropsychiatr Genet 144:174-82. 2007..39 for hoarding. We found reasonable power to detect regions of interest (lod = 2) for OCD in these families, but will need to expand our family collection to have adequate power to detect regions of interest for hoarding... - Varenicline: new treatment with efficacy in smoking cessationVictor I Reus
Department of Psychiatry, University of California School of Medicine, San Francisco, California 94143 0984, USA
Drugs Today (Barc) 43:65-75. 2007..Its targeted mechanism of action, superior efficacy and excellent tolerability make varenicline a welcome and useful addition to the therapeutic options for smoking cessation... - Belief about drug assignment and abstinence in treatment of cigarette smoking using nortriptylineSharon M Hall
University of California, San Francisco, San Francisco, CA 94143 0984, USA
Nicotine Tob Res 9:467-71. 2007.... - Influences of mood, depression history, and treatment modality on outcomes in smoking cessationAmie L Haas
Department of Psychiatry, University of California, San Francisco, CA 94304, USA
J Consult Clin Psychol 72:563-70. 2004..The study replicated results reported by R. A. Brown et al. (2001) and expanded upon them by evaluating the differential contribution of poor mood on cessation outcomes relative to MDD history... - Altering cortisol level does not change the pleasurable effects of methamphetamine in humansDebra S Harris
Drug Dependence Research Center, Langley Porter Psychiatric Institute, Department of Psychiatry, University of California, San Francisco, CA 94143 0984, USA
Neuropsychopharmacology 28:1677-84. 2003..Metyrapone was associated with significant premature ventricular complexes in two subjects during methamphetamine administration and may not be safe for those who use methamphetamine... - Chronic pregnenolone effects in normal humans: attenuation of benzodiazepine-induced sedationSharon E Meieran
University of California, San Francisco School of Medicine, San Francisco, CA, USA
Psychoneuroendocrinology 29:486-500. 2004..Further larger-scale studies, utilizing a broader range of doses and experimental conditions, are warranted... - Behavioral implications of lowering cholesterol levels: a double-blind pilot studyTom Ormiston
Santa Clara Valley Medical Center, San Jose, CA 95128, USA
Psychosomatics 44:412-4. 2003..This pilot study, although limited in size, raises the possibility that cholesterol-lowering drugs are associated with mild, time-limited increases in impulsivity and with mild, time-delayed improvements in depression ratings... - Neurotransmitters, neurosteroids and neurotrophins: new models of the pathophysiology and treatment of depressionOwen M Wolkowitz
World J Biol Psychiatry 4:98-102. 2003 - Comorbidity of bipolar disorder and substance abuse in Costa Rica: pedigree- and population-based studiesMichael A Escamilla
Department of Psychiatry, 7792, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78229-3900, USA
J Affect Disord 71:71-83. 2002..Although SA/SD may be a risk factor for precipitating BPI in those at risk, in this population comorbid BPI subjects do not have a different onset or course of BPI in comparison to BPI patients without comorbidity... - Double-blind antiglucocorticoid treatment in schizophrenia and schizoaffective disorder: a pilot studyElysa J Marco
University of California, Langley Porter Psychiatric Institute, San Francisco, USA
World J Biol Psychiatry 3:156-61. 2002..Further studies with larger sample sizes, more extensive endocrine assessments and longer duration of drug administration seem warranted... - Psychological intervention and antidepressant treatment in smoking cessationSharon M Hall
Department of Psychiatry, University of California, San Francisco, 94143 0984, USA
Arch Gen Psychiatry 59:930-6. 2002..This study compared both drugs with placebo. It also examined the efficacy of these 2 drugs and placebo with and without psychological intervention... - Genetic studies of neuropsychiatric disorders in Costa Rica: a model for the use of isolated populationsCarol A Mathews
Department of Psychiatry, University of California, San Diego, La Jolla, CA 92093 0810, USA
Psychiatr Genet 14:13-23. 2004..In this paper we highlight the studies currently being conducted by our groups in the Central Valley of Costa Rica to illustrate the potential advantages of this population for genetic studies... - Genomewide linkage disequilibrium mapping of severe bipolar disorder in a population isolateRoel A Ophoff
Neurogenetics Laboratory, University of California, San Francisco, CA, USA
Am J Hum Genet 71:565-74. 2002..This region could be important for severe psychiatric disorders, rather than for a specific phenotype... - A comparative study of obsessive-compulsive disorder in Costa Rica and the United StatesDenise A Chavira
Department of Psychiatry, University of California San Diego, San Diego, California 92037, USA
Depress Anxiety 25:609-19. 2008..However some features of OCD, such as impairment, may be culturally influenced, leading to differences in prevalence rates and treatment utilization... - Benzodiazepines in schizophrenia: prefrontal cortex atrophy predicts clinical response to alprazolam augmentationWilliam W Seeley
Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, USA
World J Biol Psychiatry 3:221-4. 2002..Mechanistic considerations and suggestions for future research are discussed... - Tic symptom profiles in subjects with Tourette Syndrome from two genetically isolated populationsCarol A Mathews
Department of Psychiatry, University of California, San Diego, La Jolla, California 92093 0810, USA
Biol Psychiatry 61:292-300. 2007..Tourette Syndrome (TS) has a complex etiology and wide variability in phenotypic expression. Identifying underlying symptom patterns may be useful for etiological and outcome studies of TS... - Genetic mapping using haplotype and model-free linkage analysis supports previous evidence for a locus predisposing to severe bipolar disorder at 5q31-33Kyung Sue Hong
Center for Neurobehavioral Genetics, University of California Los Angeles, Los Angeles, California 90095-1761, USA
Am J Med Genet B Neuropsychiatr Genet 125:83-6. 2004..These results support the suggestion that a locus at 5q31-33, together with a previously reported locus at 18q22-23, may provide the major genetic risk for BP-I in this family...