M I Restrepo

Summary

Affiliation: University of Texas Health Science Center
Country: USA

Publications

  1. pmc Clinical evaluation of the role of ceftaroline in the management of community acquired bacterial pneumonia
    Diego J Maselli
    University of Texas Health Science Center, San Antonio, Texas
    Infect Drug Resist 5:43-51. 2012
  2. ncbi request reprint Comparison of the bacterial etiology of early-onset and late-onset ventilator-associated pneumonia in subjects enrolled in 2 large clinical studies
    Marcos I Restrepo
    Division of Pulmonary and Critical Care, University of Texas Health Science Center at San Antonio, TX 77030, USA
    Respir Care 58:1220-5. 2013
  3. pmc Impact of statins and ACE inhibitors on mortality after COPD exacerbations
    Eric M Mortensen
    VERDICT research unit, South Texas Veterans Health Care System, San Antonio, Texas, USA
    Respir Res 10:45. 2009
  4. pmc Impact of prior outpatient antibiotic use on mortality for community acquired pneumonia: a retrospective cohort study
    Eric M Mortensen
    VERDICT research program, Audie L Murphy VA Hospital, 7400 Merton Minter Blvd 11C6, San Antonio, Texas, 78229, USA
    BMC Res Notes 1:120. 2008
  5. pmc A clinical pathway for community-acquired pneumonia: an observational cohort study
    Christopher R Frei
    College of Pharmacy, The University of Texas at Austin, 1 University Station A1900, Austin, TX 78712, USA
    BMC Infect Dis 11:188. 2011
  6. pmc Disparities of care for African-Americans and Caucasians with community-acquired pneumonia: a retrospective cohort study
    Christopher R Frei
    The University of Texas at Austin College of Pharmacy, Austin, TX 78712, USA
    BMC Health Serv Res 10:143. 2010
  7. doi request reprint Severe community-acquired pneumonia
    Marcos I Restrepo
    Division of Pulmonary Critical Care Medicine, South Texas Veterans Health Care System, 7400 Merton Minter Boulevard, San Antonio, TX 78229, USA
    Infect Dis Clin North Am 23:503-20. 2009
  8. doi request reprint Efficacy of intravenous infusion of doripenem
    Marcos I Restrepo
    University of Texas Health Science Center San Antonio and Audie L Murphy Division, VERDICT South Texas Veterans Health Care System, 7400 Merton Minter Blvd, San Antonio, TX 78229, USA
    Clin Infect Dis 49:S17-27. 2009
  9. doi request reprint The role of gram-negative bacteria in healthcare-associated pneumonia
    Marcos I Restrepo
    Division of Pulmonary and Critical Care Medicine at the South Texas Veterans Health Care System, Audie L Murphy Division, San Antonio, Texas 78284, USA
    Semin Respir Crit Care Med 30:61-6. 2009
  10. ncbi request reprint Severe community-acquired pneumonia: current outcomes, epidemiology, etiology, and therapy
    M I Restrepo
    University of Texas Health Science Center at San Antonio 78229 3900, USA
    Curr Opin Infect Dis 14:703-9. 2001

Detail Information

Publications53

  1. pmc Clinical evaluation of the role of ceftaroline in the management of community acquired bacterial pneumonia
    Diego J Maselli
    University of Texas Health Science Center, San Antonio, Texas
    Infect Drug Resist 5:43-51. 2012
    ..In this review, we will evaluate the pharmacological characteristics, safety, antimicrobial properties, and efficacy of ceftaroline and its applications in the treatment of CAP...
  2. ncbi request reprint Comparison of the bacterial etiology of early-onset and late-onset ventilator-associated pneumonia in subjects enrolled in 2 large clinical studies
    Marcos I Restrepo
    Division of Pulmonary and Critical Care, University of Texas Health Science Center at San Antonio, TX 77030, USA
    Respir Care 58:1220-5. 2013
    ..We assessed differences in the bacterial etiology of early-onset versus late-onset VAP...
  3. pmc Impact of statins and ACE inhibitors on mortality after COPD exacerbations
    Eric M Mortensen
    VERDICT research unit, South Texas Veterans Health Care System, San Antonio, Texas, USA
    Respir Res 10:45. 2009
    ..The purpose of our study was to examine the association of prior outpatient use of statins and angiotensin converting enzyme (ACE) inhibitors on mortality for subjects >or= 65 years of age hospitalized with acute COPD exacerbations...
  4. pmc Impact of prior outpatient antibiotic use on mortality for community acquired pneumonia: a retrospective cohort study
    Eric M Mortensen
    VERDICT research program, Audie L Murphy VA Hospital, 7400 Merton Minter Blvd 11C6, San Antonio, Texas, 78229, USA
    BMC Res Notes 1:120. 2008
    ..The purpose of this study was to examine whether prior outpatient antibiotic use is associated with increased 30-day mortality, after adjusting for potential confounders, for those subsequently hospitalized with pneumonia...
  5. pmc A clinical pathway for community-acquired pneumonia: an observational cohort study
    Christopher R Frei
    College of Pharmacy, The University of Texas at Austin, 1 University Station A1900, Austin, TX 78712, USA
    BMC Infect Dis 11:188. 2011
    ..We proposed this study to determine the impact of pathway antibiotics on patient survival, hospital length of stay (LOS), and total hospital cost...
  6. pmc Disparities of care for African-Americans and Caucasians with community-acquired pneumonia: a retrospective cohort study
    Christopher R Frei
    The University of Texas at Austin College of Pharmacy, Austin, TX 78712, USA
    BMC Health Serv Res 10:143. 2010
    ..S. hospitals with community-acquired pneumonia (CAP) are more likely than Caucasians to experience prolonged hospital length of stay (LOS), possibly due to either differential treatment decisions or patient characteristics...
  7. doi request reprint Severe community-acquired pneumonia
    Marcos I Restrepo
    Division of Pulmonary Critical Care Medicine, South Texas Veterans Health Care System, 7400 Merton Minter Boulevard, San Antonio, TX 78229, USA
    Infect Dis Clin North Am 23:503-20. 2009
    ..This article reviews epidemiologic, microbiologic, therapeutic, preventive, and outcomes data in patients who have CAP in the ICU...
  8. doi request reprint Efficacy of intravenous infusion of doripenem
    Marcos I Restrepo
    University of Texas Health Science Center San Antonio and Audie L Murphy Division, VERDICT South Texas Veterans Health Care System, 7400 Merton Minter Blvd, San Antonio, TX 78229, USA
    Clin Infect Dis 49:S17-27. 2009
    ..Overall, the clinical data indicate that doripenem has the potential to be an important option in the treatment of NP, including VAP...
  9. doi request reprint The role of gram-negative bacteria in healthcare-associated pneumonia
    Marcos I Restrepo
    Division of Pulmonary and Critical Care Medicine at the South Texas Veterans Health Care System, Audie L Murphy Division, San Antonio, Texas 78284, USA
    Semin Respir Crit Care Med 30:61-6. 2009
    ..We will focus our attention on the potential multidrug-resistant pathogens to suggest a new treatment approach for these patients...
  10. ncbi request reprint Severe community-acquired pneumonia: current outcomes, epidemiology, etiology, and therapy
    M I Restrepo
    University of Texas Health Science Center at San Antonio 78229 3900, USA
    Curr Opin Infect Dis 14:703-9. 2001
    ..A number of recent studies and guidelines addressing these issues have been published, and they will be reviewed in this article...
  11. doi request reprint Impact of macrolide therapy on mortality for patients with severe sepsis due to pneumonia
    M I Restrepo
    Veterans Evidence Based Research Dissemination Implementation Center, Audie L Murphy Veterans Affairs Hospital, San Antonio, TX, USA
    Eur Respir J 33:153-9. 2009
    ..Confirmatory studies are needed to determine whether macrolide therapy may be protective for patients with sepsis...
  12. ncbi request reprint A comparative study of community-acquired pneumonia patients admitted to the ward and the ICU
    Marcos I Restrepo
    VERDICT 11C6, South Texas Veterans Health Care System ALMD, 7400 Merton Minter Blvd, San Antonio, TX 78229, USA
    Chest 133:610-7. 2008
    ..Our aim was to compare the clinical characteristics, etiologies, and outcomes of patients with CAP who were admitted to the ICU with those admitted who were to the ward service...
  13. pmc Late admission to the ICU in patients with community-acquired pneumonia is associated with higher mortality
    Marcos I Restrepo
    Veterans Evidence Based Research Dissemination and Implementation Center, South Texas Veterans Health Care System, San Antonio, TX 78229, USA
    Chest 137:552-7. 2010
    ..Our objective was to examine the association of time to ICU admission and 30-day mortality in patients with severe CAP...
  14. doi request reprint Common medications that increase the risk for developing community-acquired pneumonia
    Marcos I Restrepo
    VERDICT, South Texas Veterans Healthcare System ALMD, 7400 Merton Minter Boulevard, San Antonio, Texas 78229, USA
    Curr Opin Infect Dis 23:145-51. 2010
    ..In addition, we review the data regarding the use of gastric-acid suppressants including histamine-2 receptor antagonists and proton pump inhibitors and the increased incidence of CAP...
  15. doi request reprint Antimicrobial resistance in Hispanic patients hospitalized in San Antonio, TX with community-acquired pneumonia
    Marcos I Restrepo
    Veterans Evidence based Research, Dissemination, and Implementation Center VERDICT, San Antonio, TX 78229, USA
    Hosp Pract (1995) 38:108-13. 2010
    ....
  16. doi request reprint [Influenza A (H1N1). Experience in the United States]
    Marcos I Restrepo
    South Texas Veterans Health Care System, Audie L Murphy Division, Departmento de Medicina, University of Texas Health Science Center, San Antonio, Texas, USA
    Arch Bronconeumol 46:13-8. 2010
    ..Therefore, the present review aims to examine the North American experience of the influenza A (H1N1) epidemic, focussing chronologically on the epidemiology of the virus, high risk groups, diagnosis, vaccination and management...
  17. doi request reprint Health economics of use fluoroquinolones to treat patients with community-acquired pneumonia
    Marcos I Restrepo
    Department of Medicine, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA
    Am J Med 123:S39-46. 2010
    ..In this review, we focus on the empiric antibiotic choices and associated costs of treatment for hospitalized patients with CAP, focusing on the use of fluoroquinolone therapy as recommended by the CAP guidelines...
  18. doi request reprint Economic burden of ventilator-associated pneumonia based on total resource utilization
    Marcos I Restrepo
    Veterans Evidence Based Research Dissemination Implementation Center, South Texas Veterans Health Care System, University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229 4404, USA
    Infect Control Hosp Epidemiol 31:509-15. 2010
    ..To characterize the current economic burden of ventilator-associated pneumonia (VAP) and to determine which services increase the cost of VAP in North American hospitals...
  19. ncbi request reprint COPD is associated with increased mortality in patients with community-acquired pneumonia
    M I Restrepo
    The Veterans Evidence based Research, Dissemination, and Implementation CenTer, Audie L Murphy Veterans Hospital, San Antonio, TX 78284, USA
    Eur Respir J 28:346-51. 2006
    ..Chronic obstructive pulmonary disease should be evaluated for inclusion in community-acquired pneumonia prediction instruments...
  20. doi request reprint Guideline-concordant antibiotic use and survival among patients with community-acquired pneumonia admitted to the intensive care unit
    Christopher R Frei
    University of Texas at Austin, College of Pharmacy, Austin, Texas, USA
    Clin Ther 32:293-9. 2010
    ..This study evaluated the survival benefit of US community-acquired pneumonia (CAP) practice guidelines in the intensive care unit (ICU) setting...
  21. ncbi request reprint Monotherapy versus combination antibiotic therapy for patients with bacteremic Streptococcus pneumoniae community-acquired pneumonia
    R Chokshi
    Department of Medicine, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78284, USA
    Eur J Clin Microbiol Infect Dis 26:447-51. 2007
    ..Randomized controlled trials are needed to determine what is the optimal empiric antimicrobial regime for patients with community-acquired pneumonia...
  22. doi request reprint Guideline-concordant therapy and outcomes in healthcare-associated pneumonia
    R T Attridge
    Feik School of Pharmacy, University of the Incarnate Word, School of Medicine, University of Texas Health Science Center at San Antonio, TX 78229 3900, USA
    Eur Respir J 38:878-87. 2011
    ..12, 95% CI 1.82-2.48) in the propensity score analysis. In nonsevere HCAP patients, GC-HCAP therapy is not associated with improved survival compared with GC-CAP therapy...
  23. ncbi request reprint Impact of statins and angiotensin-converting enzyme inhibitors on mortality of subjects hospitalised with pneumonia
    E M Mortensen
    VERDICT, ALMD UTHSCSA, Ambulatory Care 11C6, 7400 Merton Minter Boulevard, San Antonio, TX 78229, USA
    Eur Respir J 31:611-7. 2008
    ..Randomised controlled trials are needed to examine whether the use of these medications in patients hospitalised with community-acquired pneumonia may be beneficial...
  24. ncbi request reprint Medical resource utilization among community-acquired pneumonia patients initially treated with levofloxacin 750 mg daily versus ceftriaxone 1000 mg plus azithromycin 500 mg daily: a US-based study
    C R Frei
    University of Texas at Austin, Austin, TX, USA
    Curr Med Res Opin 25:859-68. 2009
    ....
  25. doi request reprint Inhaled corticosteroid use is associated with lower mortality for subjects with COPD and hospitalised with pneumonia
    R Malo de Molina
    Veterans Evidence based Research, Disseminations and Implementation Center VERDICT South Texas Veterans Health Care System, San Antonio, TX 78229, USA
    Eur Respir J 36:751-7. 2010
    ..76, 95% CI 0.70-0.83), and 90 days (OR 0.80, 95% CI 0.75-0.86). Outpatient therapy with ICS was associated with a significantly lower 30- and 90-day mortality in hospitalised COPD patients with pneumonia...
  26. ncbi request reprint Antimicrobial treatment of community-acquired pneumonia
    Marcos I Restrepo
    Division of Pulmonary and Critical Care Medicine, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78229 3900, USA
    Clin Chest Med 26:65-73. 2005
    ..Early clinical suspicion and prompt empiric antimicrobial therapies are mandatory in patients with CAP. This article provides a review of recent studies and guidelines addressing antimicrobial therapy for hospitalized patients with CAP...
  27. ncbi request reprint Incidence of Clostridium difficile-associated diarrhea before and after autologous peripheral blood stem cell transplantation for lymphoma and multiple myeloma
    J I Arango
    Department of Medicine, Division of Hematology, University of Texas Health Science Center, San Antonio, TX 78229 3900, USA
    Bone Marrow Transplant 37:517-21. 2006
    ..Patients treated with paclitaxel as part of the mobilization regimen had a lower incidence of CDAD than patients who received hematopoietic growth factor only (P = 0.01)...
  28. ncbi request reprint Community-Acquired Pneumonia Recovery in the Elderly (CAPRIE): efficacy and safety of moxifloxacin therapy versus that of levofloxacin therapy
    Antonio Anzueto
    Department of Medicine, University of Texas Health Science Center, San Antonio, TX, USA
    Clin Infect Dis 42:73-81. 2006
    ..This study aimed to determine the efficacy and safety of moxifloxacin versus that of levofloxacin for the treatment of CAP in hospitalized elderly patients (age, > or = 65 years)...
  29. ncbi request reprint Impact of a lung transplantation donor-management protocol on lung donation and recipient outcomes
    Luis F Angel
    Division of Pulmonary and Critical Care Medicine, Division of Cardiothoracic Surgery, Center for Epidemiology and Biostatistics, University of Texas Health Science Center at San Antonio, TX 78229
    Am J Respir Crit Care Med 174:710-6. 2006
    ..One of the limitations associated with lung transplantation is the lack of available organs...
  30. ncbi request reprint Antibiotic therapy and 48-hour mortality for patients with pneumonia
    Eric M Mortensen
    Veterans Evidence Based Research Dissemination and Implementation Center, South Texas Veterans Health Care System, San Antonio, Tex 78284, USA
    Am J Med 119:859-64. 2006
    ..Our aim was to determine whether the use of guideline-concordant antibiotic therapy is associated with decreased mortality within the first 48 hours after admission for patients with pneumonia...
  31. pmc The impact of prior outpatient ACE inhibitor use on 30-day mortality for patients hospitalized with community-acquired pneumonia
    Eric M Mortensen
    VERDICT Research Center, Audie L Murphy VA Hospital, San Antonio, Texas, USA
    BMC Pulm Med 5:12. 2005
    ..We examined the effect of prior outpatient use of ACE inhibitors on mortality for patients hospitalized with community-acquired pneumonia...
  32. doi request reprint Postoperative complications in the seriously mentally ill: a systematic review of the literature
    Laurel A Copeland
    Veterans Affairs HSRD South Texas Veterans Health Care System VERDICT, San Antonio, TX 78229 4404, USA
    Ann Surg 248:31-8. 2008
    ..To determine the knowledge base on clinical outcomes of surgery among persons diagnosed with serious mental illness...
  33. pmc The effect of prior statin use on 30-day mortality for patients hospitalized with community-acquired pneumonia
    Eric M Mortensen
    VERDICT Research Center, Audie L Murphy VA Hospital, San Antonio, Texas, USA
    Respir Res 6:82. 2005
    ..We examined the effect of prior outpatient use of statins on mortality for patients hospitalized with community-acquired pneumonia...
  34. ncbi request reprint Association of hydrophilic versus lipophilic angiotensin-converting enzyme inhibitor use on pneumonia-related mortality
    Eric M Mortensen
    VERDICT Research Center, South Texas Veterans Health Care System, San Antonio, Texas 78284, USA
    Am J Med Sci 336:462-6. 2008
    ..Our aim was to examine the associations of prior outpatient use of lipophilic and hydrophilic ACE inhibitors on mortality for patients hospitalized with community-acquired pneumonia...
  35. ncbi request reprint Pulmonary disease among inpatient decedents: Impact of schizophrenia
    Laurel A Copeland
    South Texas Veterans Health Care System VERDICT HSR and D, 7400 Merton Minter 11c6, San Antonio, Texas 78229 4404, United States
    Prog Neuropsychopharmacol Biol Psychiatry 31:720-6. 2007
    ..Determine the risk associated with schizophrenia for common pulmonary illness (pneumonia and chronic obstructive pulmonary disorder (COPD)) during the last year of life...
  36. ncbi request reprint Impact of previous statin and angiotensin II receptor blocker use on mortality in patients hospitalized with sepsis
    Eric M Mortensen
    VERDICT Research Center, South Texas Veterans Health Care System, San Antonio, Texas 78284, USA
    Pharmacotherapy 27:1619-26. 2007
    ..To examine the effect of previous outpatient use of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors (statins) and/or angiotensin II receptor blockers (ARBs) on 30-day mortality in patients hospitalized with sepsis...
  37. pmc Diagnosis of pulmonary malignancy after hospitalization for pneumonia
    Eric M Mortensen
    VERDICT Research Program and South Texas Veterans Health Care System, Audie L Murphy Division, San Antonio, TX, USA
    Am J Med 123:66-71. 2010
    ..Our aims were to assess the frequency of the diagnosis of pulmonary malignancy, and to identify risk factors for pulmonary malignancy following hospitalization for pneumonia...
  38. pmc Association of hypoglycemia with mortality for subjects hospitalized with pneumonia
    Eric M Mortensen
    VERDICT research program, Medicine Service, Audie L Murphy Division South Texas Veterans Health Care System, University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229, USA
    Am J Med Sci 339:239-43. 2010
    ..The purpose of this study was to examine whether hypoglycemia (<70 mg/dL) is associated with increased 30-day mortality, after adjusting for potential confounders, for adults hospitalized with pneumonia...
  39. pmc Activity of daptomycin against recent North American isolates of Streptococcus pneumoniae
    M I Restrepo
    Department of Medicine, University of Texas Health Science Center, San Antonio, Texas 78229, USA
    Antimicrob Agents Chemother 47:2974-7. 2003
    ..Daptomycin zone diameters varied little on the same media...
  40. doi request reprint Antifungal prophylaxis with voriconazole or itraconazole in lung transplant recipients: hepatotoxicity and effectiveness
    J Cadena
    Division of Infectious Diseases, Department of Medicine, The University of Texas Health Science Center at San Antonio UTHSCSA, TX, USA
    Am J Transplant 9:2085-91. 2009
    ..Voriconazole prophylaxis after lung transplantation was associated with a higher incidence of hepatotoxicity and similar clinical effectiveness when compared to itraconazole...
  41. ncbi request reprint Performance of a hybrid central venous catheter utilized for both peripheral blood stem cell harvest and transplant support of patients undergoing autologous peripheral blood stem cell transplantation
    A Restrepo
    Department of Medicine, University of Texas Health Science Center, San Antonio, USA
    Bone Marrow Transplant 30:389-95. 2002
    ....
  42. doi request reprint Fibrin ring granulomas in Rickettsia typhi infection
    Marcos I Restrepo
    Veterans Evidence Research Dissemination and Implementation Center VERDICT, South Texas Veterans Health Care System, San Antonio, TX 78229, USA
    Diagn Microbiol Infect Dis 66:322-5. 2010
    ..The patient was given doxycycline, and the fever resolved within 48 h. We propose that fibrin ring granulomas also occur in murine typhus...
  43. ncbi request reprint Reply to Bodi et al
    Eric M Mortensen
    Clin Infect Dis 42:1345. 2006
  44. ncbi request reprint When to switch therapy in patients with severe community-acquired pneumonia
    Eric M Mortensen
    Ann Intern Med 148:625; author reply 625-6. 2008
  45. ncbi request reprint Etiology of community-acquired pneumonia in hospitalized patients in chile: the increasing prevalence of respiratory viruses among classic pathogens
    Alejandro Diaz
    Departamento de Enfermedades Respiratorias, Pontificia Universidad Catolica de Chile, Santiago, Chile
    Chest 131:779-87. 2007
    ..The aim of this study was to determine the microbial etiology of CAP in adults and to identify the risk factors for various specific pathogens...
  46. pmc Statins and outcomes in patients with pneumonia: not only healthy user bias
    Eric M Mortensen
    BMJ 333:1123-4. 2006
  47. ncbi request reprint Steroid infusion for severe pneumonia: not so fast
    Marcos I Restrepo
    Am J Respir Crit Care Med 172:781; author reply 782-3. 2005
  48. ncbi request reprint The role of new therapies for severe community-acquired pneumonia
    Marcos I Restrepo
    Division of Pulmonary and Crit Care Med, South Texas Veterans Healthcare System, Audie L Murphy Division, University of Texas Health Science Center at San Antonio 78229, USA
    Curr Opin Infect Dis 19:557-64. 2006
    ....
  49. ncbi request reprint Impact of guideline-concordant empiric antibiotic therapy in community-acquired pneumonia
    Christopher R Frei
    University of Texas at Austin College of Pharmacy, Austin, Tex, USA
    Am J Med 119:865-71. 2006
    ..We evaluated the impact of guideline-concordant empiric antibiotic therapy on time to clinical stability, time to switch therapy, length of hospital stay, and mortality among patients with community-acquired pneumonia...
  50. ncbi request reprint Prognosis factors and outcome of community-acquired pneumonia needing mechanical ventilation
    Eva Tejerina
    Intensive Care Unit, Hospital Universitario de Getafe, 28905 Getafe, Madrid, Spain
    J Crit Care 20:230-8. 2005
    ....
  51. ncbi request reprint Incidence, risk factors, and outcome of ventilator-associated pneumonia
    Eva Tejerina
    Intensive Care Unit, Hospital Universitario de Getafe, 28905 Getafe, Madrid, Spain
    J Crit Care 21:56-65. 2006
    ..The purpose of this study is to determine the incidence, risk factors, and outcome of ventilator-associated pneumonia (VAP)...
  52. doi request reprint Evaluation of ICU admission criteria and diagnostic methods for patients with severe community-acquired pneumonia: current practice survey
    Marcos I Restrepo
    Chest 133:828-9. 2008
  53. doi request reprint Silver-coated endotracheal tubes and incidence of ventilator-associated pneumonia: the NASCENT randomized trial
    Marin H Kollef
    Washington University School of Medicine, 660 S Euclid Ave, St Louis, MO 63110, USA
    JAMA 300:805-13. 2008
    ..Ventilator-associated pneumonia (VAP) causes substantial morbidity. A silver-coated endotracheal tube has been designed to reduce VAP incidence by preventing bacterial colonization and biofilm formation...