Silvia Resta-Lenert

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi request reprint Probiotics and commensals reverse TNF-alpha- and IFN-gamma-induced dysfunction in human intestinal epithelial cells
    Silvia Resta-Lenert
    Department of Medicine, University of California, San Diego, School of Medicine, San Diego, California, USA
    Gastroenterology 130:731-46. 2006
  2. ncbi request reprint Inhibition of epithelial chloride secretion by butyrate: role of reduced adenylyl cyclase expression and activity
    S Resta-Lenert
    Department of Medicine, University of California, San Diego, School of Medicine, San Diego, California 92103, USA
    Am J Physiol Cell Physiol 281:C1837-49. 2001
  3. ncbi request reprint Enteroinvasive bacteria alter barrier and transport properties of human intestinal epithelium: role of iNOS and COX-2
    Silvia Resta-Lenert
    Department of Medicine, and Biomedical Sciences Ph D Program, University of California, San Diego, School of Medicine, San Diego, California, USA
    Gastroenterology 122:1070-87. 2002
  4. pmc Live probiotics protect intestinal epithelial cells from the effects of infection with enteroinvasive Escherichia coli (EIEC)
    S Resta-Lenert
    Department of Medicine, School of Medicine, University of California San Diego, UCSD Medical Center 8414, 200 West Arbor Drive, San Diego, CA 92103, USA
    Gut 52:988-97. 2003
  5. ncbi request reprint Epithelial dysfunction associated with the development of colitis in conventionally housed mdr1a-/- mice
    Silvia Resta-Lenert
    Division of Gastroenterology, Department of Medicine, University of California, School of Medicine, San Diego, CA 92103, USA
    Am J Physiol Gastrointest Liver Physiol 289:G153-62. 2005
  6. pmc Muc17 protects intestinal epithelial cells from enteroinvasive E. coli infection by promoting epithelial barrier integrity
    Silvia Resta-Lenert
    Department of Medicine, University of California San Diego, USA
    Am J Physiol Gastrointest Liver Physiol 300:G1144-55. 2011

Research Grants

  1. Commensals and Probiotics: Role in Intestinal Physiology
    Silvia Resta Lenert; Fiscal Year: 2007

Collaborators

Detail Information

Publications6

  1. ncbi request reprint Probiotics and commensals reverse TNF-alpha- and IFN-gamma-induced dysfunction in human intestinal epithelial cells
    Silvia Resta-Lenert
    Department of Medicine, University of California, San Diego, School of Medicine, San Diego, California, USA
    Gastroenterology 130:731-46. 2006
    ..We hypothesized that probiotics and/or commensals may also reverse epithelial damage produced by cytokines...
  2. ncbi request reprint Inhibition of epithelial chloride secretion by butyrate: role of reduced adenylyl cyclase expression and activity
    S Resta-Lenert
    Department of Medicine, University of California, San Diego, School of Medicine, San Diego, California 92103, USA
    Am J Physiol Cell Physiol 281:C1837-49. 2001
    ..However, these effects may not all be equally important in determining Cl(-) secretion in response to physiologically relevant secretagogues...
  3. ncbi request reprint Enteroinvasive bacteria alter barrier and transport properties of human intestinal epithelium: role of iNOS and COX-2
    Silvia Resta-Lenert
    Department of Medicine, and Biomedical Sciences Ph D Program, University of California, San Diego, School of Medicine, San Diego, California, USA
    Gastroenterology 122:1070-87. 2002
    ....
  4. pmc Live probiotics protect intestinal epithelial cells from the effects of infection with enteroinvasive Escherichia coli (EIEC)
    S Resta-Lenert
    Department of Medicine, School of Medicine, University of California San Diego, UCSD Medical Center 8414, 200 West Arbor Drive, San Diego, CA 92103, USA
    Gut 52:988-97. 2003
    ..The colonic epithelium maintains a life long reciprocally beneficial interaction with the colonic microbiota. Disruption is associated with mucosal injury...
  5. ncbi request reprint Epithelial dysfunction associated with the development of colitis in conventionally housed mdr1a-/- mice
    Silvia Resta-Lenert
    Division of Gastroenterology, Department of Medicine, University of California, School of Medicine, San Diego, CA 92103, USA
    Am J Physiol Gastrointest Liver Physiol 289:G153-62. 2005
    ..Our data support the hypothesis that alterations in the intestinal barrier alone, in the absence of immune dysfunction, may rapidly lead to colitis in the setting of a normal colonic flora...
  6. pmc Muc17 protects intestinal epithelial cells from enteroinvasive E. coli infection by promoting epithelial barrier integrity
    Silvia Resta-Lenert
    Department of Medicine, University of California San Diego, USA
    Am J Physiol Gastrointest Liver Physiol 300:G1144-55. 2011
    ..In conclusion, these data suggest that both native and exogenous MUC17 play a role in attachment and invasion of EIEC in colonic cell lines and in maintaining epithelial barrier function...

Research Grants2

  1. Commensals and Probiotics: Role in Intestinal Physiology
    Silvia Resta Lenert; Fiscal Year: 2007
    ....