Research Topics
| T A ReponenSummaryAffiliation: University of Cincinnati Country: USA Publications
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Detail Information
Publications
Infant origins of childhood asthma associated with specific moldsTiina Reponen
Department of Environmental Health, University of Cincinnati, Cincinnati, OH 45267 0056, USA
J Allergy Clin Immunol 130:639-644.e5. 2012..The specific cause or causes of asthma development must be identified to prevent this disease...- Characteristics of airborne actinomycete sporesT A Reponen
Aerosol Research and Exposure Assessment Laboratory, Department of Environmental Health, University of Cincinnati, Cincinnati, Ohio, 45267 0056, USA
Appl Environ Microbiol 64:3807-12. 1998..Therefore, alternatives to commonly used cultivation methods need to be developed for the enumeration of actinomycete spores... - Visually observed mold and moldy odor versus quantitatively measured microbial exposure in homesTiina Reponen
University of Cincinnati, Department of Environmental Health, Cincinnati, OH 45267 0056, USA
Sci Total Environ 408:5565-74. 2010..air. Future analysis will indicate which, if any, of the assessment methods is associated with the development of asthma... 
Influence of home characteristics on airborne and dustborne endotoxin and β-D-glucanUmesh Singh
Department of Environmental Health, University of Cincinnati, P O Box 670056, Cincinnati, OH 45267 0056, USA
J Environ Monit 13:3246-53. 2011..Furthermore, even though statistically significant, the correlations between airborne and dustborne contaminants were weak. This indicates that airborne concentrations cannot be reliably predicted based on dustborne concentrations...- High environmental relative moldiness index during infancy as a predictor of asthma at 7 years of ageTiina Reponen
Department of Environmental Health, University of Cincinnati, Cincinnati, Ohio 45267 0056, USA
Ann Allergy Asthma Immunol 107:120-6. 2011..Mold exposures may contribute to the development of asthma, but previous studies have lacked a standardized approach to quantifying exposures... 
Dynamic monitoring of the dust pickup efficiency of vacuum cleanersTiina Reponen
Aerosol Research and Exposure Assessment Laboratory, Department of Environmental Health, University of Cincinnati, P O Box 670056, Cincinnati, OH 45267 0056, USA
AIHA J (Fairfax, Va) 63:689-97. 2002..This suggests that a small aerosol photometer similar to a light-scattering smoke detector would be beneficial in vacuum cleaners used for cleaning surfaces contaminated with leaded dust and biological particles (including allergens)...- Effect of fit testing on the protection offered by n95 filtering facepiece respirators against fine particles in a laboratory settingTiina Reponen
Department of Environmental Health, University of Cincinnati, PO Box 670056, Cincinnati, OH 45267 0056, USA
Ann Occup Hyg 55:264-71. 2011..Particle size ranges were representative of individual viruses and bacteria (aerodynamic diameter d(a) = 0.04-1.3 μm)... - Respiratory protection provided by N95 filtering facepiece respirators against airborne dust and microorganisms in agricultural farmsShu-An Lee
University of Cincinnati, Department of Environmental Health, Cincinnati, Ohio 45267-0056, USA
J Occup Environ Hyg 2:577-85. 2005..The method is a promising tool for further epidemiological and intervention studies in agricultural and other similar occupational and nonoccupational environments... - Personal exposure to airborne dust and microorganisms in agricultural environmentsShu-An Lee
Department of Environmental Health, University of Cincinnati, Cincinnati, Ohio 45267-0056, USA
J Occup Environ Hyg 3:118-30. 2006..Overall, the combined exposure to airborne dust and microorganisms was found to be more severe during harvesting than in animal confinements... - Assessment of fungal contamination in moldy homes: comparison of different methodsR Todd Niemeier
Department of Environmental Health, Center for Health-Related Aerosol Studies, University of Cincinnati, Cincinnati, Ohio 45267-0056, USA
J Occup Environ Hyg 3:262-73. 2006..Because of the small sample size of this study, however, further research is needed to better understand the observed relationships in this study... - Physical collection efficiency of filter materials for bacteria and virusesNancy Clark Burton
Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health 4676 Columbia Parkway, MS R 11, Cincinnati, OH 45226, USA
Ann Occup Hyg 51:143-51. 2007..A 4-h loading did not cause significant change in the physical collection efficiency of the tested filters... - Size distribution of airborne mist and endotoxin-containing particles in metalworking fluid environmentsHongxia Wang
University of Cincinnati, Department of Environmental Health, Cincinnati, Ohio 45267 2263, USA
J Occup Environ Hyg 4:157-65. 2007..The results call for the size-selective measurement of particles and endotoxin for more comprehensive exposure assessment in MWF facilities... - Exposure matrices of endotoxin, (1→3)-β-d-glucan, fungi, and dust mite allergens in flood-affected homes of New OrleansAtin Adhikari
Department of Environmental Health, University of Cincinnati, Cincinnati, OH 45267 0056, USA
Sci Total Environ 408:5489-98. 2010..No conclusive correlations were found between the three environmental monitoring methods. The findings support the use of multiple methods when assessing exposure to microbial contaminants... - Aerosolization of fungi, (1-->3)-beta-D glucan, and endotoxin from flood-affected materials collected in New Orleans homesAtin Adhikari
Center for Health Related Aerosol Studies, Department of Environmental Health, University of Cincinnati, P O Box 670056, 3223 Eden Avenue, Cincinnati, OH 45267 0056, USA
Environ Res 109:215-24. 2009..We believe the findings will be significant during similar disasters in other regions of the world including major coastal floods from tsunamis... - Influence of dog ownership and high endotoxin on wheezing and atopy during infancyPaloma Campo
Department of Internal Medicine, Immunology Division, University of Cincinnati, Cincinnati, OH 45267-0563, USA
J Allergy Clin Immunol 118:1271-8. 2006..CLINICAL IMPLICATIONS: A home environment with many dogs and high levels of endotoxin may be conducive to reduced wheezing in infancy... - Manikin-based performance evaluation of N95 filtering-facepiece respirators challenged with nanoparticlesAnna Balazy
Department of Environmental Health, Center for Health-Related Aerosol Studies, University of Cincinnati, OH 45267-0056, USA
Ann Occup Hyg 50:259-69. 2006..096 m(3)) test chamber and in a large (24.3 m(3)) walk-in chamber were found essentially the same, thus, suggesting that laboratory-based evaluations have a good potential to adequately represent the respirator field performance... - Breast-feeding, aeroallergen sensitization, and environmental exposures during infancy are determinants of childhood allergic rhinitisChristopher D Codispoti
Department of Internal Medicine, Division of Immunology, Allergy and Rheumatology, University of Cincinnati, Cincinnati, Ohio 4267 0563, USA
J Allergy Clin Immunol 125:1054-1060.e1. 2010..Infant predictors of early childhood allergic rhinitis (AR) are poorly understood... - Size-fractionated (1-->3)-beta-D-glucan concentrations aerosolized from different moldy building materialsSung Chul Seo
Center for Health Related Aerosol Studies, Department of Environmental Health, University of Cincinnati, Cincinnati, OH 45267 0056, USA
Sci Total Environ 407:806-14. 2009..Furthermore, the contribution of fragments may vary between species and appears to be higher for S. chartarum than for A. versicolor... - Quantitative PCR analysis of house dust can reveal abnormal mold conditionsTeija Meklin
National Exposure Research Laboratory, US Environmental Protection Agency, Cincinnati, OH 45268, USA
J Environ Monit 6:615-20. 2004..Culturing underestimated the concentrations of these four species by 2 to 3 orders of magnitude compared to QPCR... - Correlation of ambient inhalable bioaerosols with particulate matter and ozone: a two-year studyAtin Adhikari
Department of Environmental Health, University of Cincinnati, Cincinnati, OH 45267-0056, USA
Environ Pollut 140:16-28. 2006..Our study concluded that several types of inhalable airborne fungi and pollen, particulate matter, and ozone could be positively correlated as a result of the atmospheric temperature influence... - Fungal spore source strength tester: laboratory evaluation of a new conceptSatheesh K Sivasubramani
Center for Health-Related Aerosol Studies, Department of Environmental Health, University of Cincinnati, 3223 Eden Ave, P.O. Box 670056, Cincinnati, OH 45267-0056, USA
Sci Total Environ 329:75-86. 2004..Our data suggest that the FSSST provides very favorable conditions for the spore aerosolization and thus can be used in the field to assess the maximum potential spore release from a fungal source... - Effect of particle size on respiratory protection provided by two types of N95 respirators used in agricultural settingsKyungmin Jacob Cho
Department of Environmental Health, University of Cincinnati, Cincinnati, Ohio 45267, USA
J Occup Environ Hyg 7:622-7. 2010..7 to 10 μm. WPFs for the ER were higher than the FFR for all particle size ranges. WPFs for both respirator types increased with increasing particle size... - Evaluation of bioaerosol exposures during conditioning of biofilter organic media bedsEd Barth
Department of Environmental Health, College of Medicine, University of Cincinnati, OH, USA
Appl Occup Environ Hyg 17:10-4. 2002..4) Protective outer wear, goggles, and gloves should be worn to minimize health risks associated with clothing garments contaminated by microorganisms... - The effect of home characteristics on dust antigen concentrations and loads in homesSeung-Hyun Cho
Department of Environmental Health, University of Cincinnati, Cincinnati, OH 45267-0056, USA
Sci Total Environ 371:31-43. 2006..This study encompassed a wide range of home characteristics and various antigen types. Our findings provide information on home characteristics that can be used for allergen avoidance and in planning future exposure assessment studies... - Aerosolization of particulate (1-->3)-beta-D-glucan from moldy materialsSung Chul Seo
Center for Health Related Aerosol Studies, Department of Environmental Health, University of Cincinnati, Cincinnati, OH 45267 0056, USA
Appl Environ Microbiol 74:585-93. 2008..chartarum particles from building materials. These results provide important background information for design of future laboratory or animal experiments, as well as for interpretation of field measurement data... - Associations between multiple environmental exposures and Glutathione S-Transferase P1 on persistent wheezing in a birth cohortKathy T Schroer
Division of Asthma Research, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229 3039, USA
J Pediatr 154:401-8, 408.e1. 2009.... - Specific fungal exposures, allergic sensitization, and rhinitis in infantsMelissa Osborne
Department of Environmental Health, University of Cincinnati, Cincinnati, OH, USA
Pediatr Allergy Immunol 17:450-7. 2006..05), and Cladosporium and SPT(+) to aeroallergens (p < 0.05). This study indicates that health outcome may vary by fungal genera; some fungal types may have sensitizing effects while others may have a beneficial role... - The effect of filter material on bioaerosol collection of Bacillus subtilis spores used as a Bacillus anthracis simulantNancy Clark Burton
Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, Division of Surveillance, Hazard Evaluations, and Field Studies, 4676 Columbia Parkway, Cincinnati, OH 45226, USA
J Environ Monit 7:475-80. 2005..In summary, the MCE and 1 microm PTFE filters in combination with vortexing and shaker extraction demonstrated the best performance for the filter collection and extraction of BG spores... - Analysis of short-term influences of ambient aeroallergens on pediatric asthma hospital visitsWei Zhong
Department of Environmental Health, University of Cincinnati, PO Box 670056, Ohio 45267 0056, USA
Sci Total Environ 370:330-6. 2006..Their relative risks on asthma hospital visits with respect to a 100 counts/m(3) increase in concentration were in the range of 1.23 to 1.54. The effects in causing the asthma exacerbation were delayed by 3 or 5 days... - Concentration gradient patterns of aerosol particles near interstate highways in the Greater Cincinnati airshedTiina Reponen
Department of Environmental Health, University of Cincinnati, Cincinnati, Ohio, USA
J Environ Monit 5:557-62. 2003..This characterization is crucial especially when the exposure data are to be used in epidemiological studies... - Fungal fragments as indoor air biocontaminantsRafał L Górny
Center for Health Related Aerosol Studies, Department of Environmental Health, University of Cincinnati, Cincinnati, Ohio 45267 0056, USA
Appl Environ Microbiol 68:3522-31. 2002..This study suggests that future fungal spore investigations in buildings with mold problems should include the quantitation of fungal fragments... - Filter performance of n99 and n95 facepiece respirators against viruses and ultrafine particlesRobert M Eninger
Department of Environmental Health, University of Cincinnati, Cincinnati, OH, USA
Ann Occup Hyg 52:385-96. 2008..5 mum). Filter penetration of the tested biological aerosols did not exceed that of inert NaCl aerosol. The results suggest that inert NaCl aerosols may generally be appropriate for modeling filter penetration of similarly sized virions... - A land-use regression model for estimating microenvironmental diesel exposure given multiple addresses from birth through childhoodPatrick H Ryan
Department of Environmental Health, University of Cincinnati Medical Center, United States
Sci Total Environ 404:139-47. 2008..Findings indicate that using birth addresses to estimate a child's exposure may result in exposure misclassification for some children who spend a significant amount of time at a location with high exposure to DEP... - Assessment of human exposure to airborne fungi in agricultural confinements: personal inhalable sampling versus stationary samplingAtin Adhikari
Center for Health Related Aerosol Studies, Department of Environmental Health, University of Cincinnati, 3223 Eden Avenue, PO Box 670056, Cincinnati, Ohio 45267 0056, USA
Ann Agric Environ Med 11:269-77. 2004..The results indicate that personal exposure of agricultural workers in confinements may be adequately assessed by placing several Button Samplers simultaneously operating in a static stationary mode throughout the work site... - Exposure to traffic-related particles and endotoxin during infancy is associated with wheezing at age 3 yearsPatrick H Ryan
Department of Environmental Health, University of Cincinnati College of Medicine, Cincinnati, OH, USA
Am J Respir Crit Care Med 180:1068-75. 2009..Murine models demonstrate a synergistic production of reactive oxygen species on coexposure to diesel exhaust particles and endotoxin... - Exposure to traffic exhaust and night cough during early childhood: the CCAAPS birth cohortHeidi Sucharew
Department of Environmental Health, University of Cincinnati Medical Center, Cincinnati, OH 45267 0056, USA
Pediatr Allergy Immunol 21:253-9. 2010..73, 95% CI: 0.53, 1.01). No other factors were significant. These results suggest that traffic exhaust exposure may be a risk factor for night cough in young children... - Genetic and environmental risk factors for childhood eczema development and allergic sensitization in the CCAAPS cohortJocelyn M Biagini Myers
Division of Asthma Research, Department of Pediatrics, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229 3039, USA
J Invest Dermatol 130:430-7. 2010..The results also demonstrate a susceptibility effect of the combination of CD14 and IL4Ralpha SNPs with eczema... - Performance of an N95 filtering facepiece particulate respirator and a surgical mask during human breathing: two pathways for particle penetrationSergey A Grinshpun
Center for Health Related Aerosol Studies, Department of Environmental Health, University of Cincinnati, Cincinnati, Ohio 45267 0056, USA
J Occup Environ Hyg 6:593-603. 2009.... - What does respirator certification tell us about filtration of ultrafine particles?Robert M Eninger
Department of Environmental Health, University of Cincinnati, Cincinnati, Ohio
J Occup Environ Hyg 5:286-95. 2008..Possible strategies to assess ultrafine particle penetration in the certification protocol are discussed... - Do N95 respirators provide 95% protection level against airborne viruses, and how adequate are surgical masks?Anna Bałazy
Center for Health Related Aerosol Studies, Department of Environmental Health, University of Cincinnati, Cincinnati, OH, USA
Am J Infect Control 34:51-7. 2006..Filtering face piece respirators are usually tested utilizing nonbiologic particles, whereas their use often aims at reducing exposure to biologic aerosols, including infectious agents such as viruses and bacteria... - A small change in the design of a slit bioaerosol impactor significantly improves its collection characteristicsSergey A Grinshpun
Center for Health Related Aerosol Studies, Department of Environmental Health, University of Cincinnati, Cincinnati, Ohio 45267 0056, USA
J Environ Monit 9:855-61. 2007..Data from a demonstration field study, conducted with the two samplers in environments containing a variety of fungal species, supported the laboratory findings... - Laboratory and field evaluation of a new personal sampling system for assessing the protection provided by the N95 filtering facepiece respirators against particlesShu-An Lee
Department of Environmental Health, University of Cincinnati, P.O. Box 670056, Cincinnati, OH 45267-0056, USA
Ann Occup Hyg 49:245-57. 2005..In future studies, it would be beneficial if the laboratory data could be integrated with the field database... - Environmental risk factors of rhinitis in early infancyJocelyn M Biagini
Department of Environmental Health, University of Cincinnati, and Division of Allergy and Immunology, Department of Pediatrics, Cincinati Children s Hospital Medical Center, OH 45267 0056, USA
Pediatr Allergy Immunol 17:278-84. 2006..This study suggests that ETS exposure, rather than visible mold, is associated with rhinitis and allergic rhinitis in infants. The analysis also suggests that mold may be a stronger risk factor for URI that ETS... - Assessment of electrical charge on airborne microorganisms by a new bioaerosol sampling methodShu An Lee
Center for Health Related Aerosol Studies, Department of Environmental Health, University of Cincinnati, Cincinnati, Ohio, USA
J Occup Environ Hyg 1:127-38. 2004..This adds a signature to the sampled microorganisms that may assist in their identification or differentiation, for example, in an anti-bioterrorism network... - Control of aerosol contaminants in indoor air: combining the particle concentration reduction with microbial inactivationSergey A Grinshpun
Center for Health Related Aerosol Studies, Department of Environmental Health, University of Cincinnati, 3223 Eden Avenue, PO Box 670056, Cincinnati, Ohio 45267 0056, USA
Environ Sci Technol 41:606-12. 2007..subtilis spores were inactivated in 10 min, and about 90% or greater after 30 min. The biological and chemical mechanisms that led to the inactivation of stress-resistant airborne viruses and bacterial spores were reviewed... - Estimating sampling frequency in pollen exposure assessment over timeJunxiang Luo
Department of Environmental Health, Division of Epidemiology and Biostatistics, University of Cincinnati, Ohio, USA
J Environ Monit 8:955-62. 2006.... - Evaluation and optimization of an urban PM2.5 monitoring networkDainius Martuzevicius
Center for Health-Related Aerosol Studies, University of Cincinnati, Cincinnati, OH, USA
J Environ Monit 7:67-77. 2005..5) mass monitors should be increased to better represent spatial and temporal variations of the markers of local air pollution sources... - Release of Streptomyces albus propagules from contaminated surfacesRafał L Górny
Department of Environmental Health, Center for Health Related Aerosol Studies, University of Cincinnati, Cincinnati, OH 45267 0056, USA
Environ Res 91:45-53. 2003..Measurement of the number of S. albus fragments in the vicinity of a contaminated area, as an alternative to conventional air or surface sampling, appears to be a promising approach for quantitative exposure assessment... - Effect of gaseous chlorine dioxide on indoor microbial contaminantsNancy Clark Burton
Division of Surveillance, Hazard Evaluations, and Field Studies, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, Cincinnati, OH 45226, USA
J Air Waste Manag Assoc 58:647-56. 2008..The laboratory study supported these results and showed a nonsignificant increase in the concentration of (1 --> 3)-beta-D-glucan after ClO2 treatment... - Mold damage in homes and wheezing in infantsSeung-Hyun Cho
Department of Environmental Health, University of Cincinnati, Cincinnati, Ohio 45267-0056, USA
Ann Allergy Asthma Immunol 97:539-45. 2006..CONCLUSIONS: Visible mold was shown to be a significant risk factor for recurrent wheezing in infants at high risk of developing atopic disorders, whereas HDM exposure did not significantly increase the risk... - Mold exposure during infancy as a predictor of potential asthma developmentYulia Y Iossifova
Department of Environmental Health, University of Cincinnati, Cincinnati, Ohio 45267 0056, USA
Ann Allergy Asthma Immunol 102:131-7. 2009..Exposure to mold has been associated with exacerbation of asthma symptoms in children... - Evaluation of bioaerosol components, generation factors, and airborne transport associated with lime treatment of contaminated sedimentEdwin F Barth
National Risk Management Research Laboratory, Office of Research and Development, U S Environmental Protection Agency, Cincinnati, OH 45268, USA
J Air Waste Manag Assoc 59:540-52. 2009..Quantitative scaling analysis and whether the system represents actual environmental conditions were not studied... - Effect of electrical charges and fields on injury and viability of airborne bacteriaGediminas Mainelis
Aerosol Research and Exposure Assessment Laboratory, Department of Environmental Health, University of Cincinnati, Cincinnati, Ohio, USA
Biotechnol Bioeng 79:229-41. 2002..The findings from this study can also be used in the development of new bioaerosol sampling methods based on electrostatic principles... - Relative moldiness index as predictor of childhood respiratory illnessStephen J Vesper
US Environmental Protection Agency, Cincinnati, OH, USA
J Expo Sci Environ Epidemiol 17:88-94. 2007..27). Conversely, a method developed and validated in this paper, using the RMI index fit to a logistic function, can be used to predict the occurrence of illness in homes and allows stake-holders the choice among various levels of risk... - Rapid counting of liquid-borne microorganisms by light scattering spectrometryGediminas Mainelis
Department of Environmental Sciences, Rutgers, The State University of New Jersey, New Brunswick, NJ, USA
Ann Agric Environ Med 12:141-8. 2005..The observed difference in counting efficiency may serve as a basis for differentiating biological from non-biological particles in liquid samples... - Effect of building frame and moisture damage on microbiological indoor air quality in school buildingsTeija Meklin
National Public Health Institute, Department of Environmental Health, P O Box 95, FIN 70701 Kuopio, Finland
AIHA J (Fairfax, Va) 64:108-16. 2003..In addition, the presence of Oidiodendron as well as elevated concentrations of Cladosporium and actinobacteria were associated with moisture damage in concrete schools... - Mold and endotoxin levels in the aftermath of Hurricane Katrina: a pilot project of homes in New Orleans undergoing renovationGinger L Chew
Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, New York 10034 4206, USA
Environ Health Perspect 114:1883-9. 2006..After Hurricane Katrina, many New Orleans homes remained flooded for weeks, promoting heavy microbial growth... - Working Group report 4: exposure assessment for biological agentsPeter S Thorne
College of Public Health, University of Iowa, Iowa City, IA 55242 5000, USA
Am J Ind Med 46:419-22. 2004..Endotoxin exposure assessment using the Limulus amebocyte lysate method is a high priority for harmonization because of its importance as a pulmonary inflammatory agent in many occupational settings... - A role for environmental engineering and science in preventing bioaerosol-related diseaseJordan Peccia
Yale University, USA
Environ Sci Technol 42:4631-7. 2008 - Comparison of mold concentrations quantified by MSQPCR in indoor and outdoor air sampled simultaneouslyTeija Meklin
National Public Health Institute, Finland
Sci Total Environ 382:130-4. 2007..5). These results suggest that interpretation of the meaning of short-term (<48 h) mold measurements in indoor and outdoor air samples must be made with caution... - Respiratory performance offered by N95 respirators and surgical masks: human subject evaluation with NaCl aerosol representing bacterial and viral particle size rangeShu An Lee
Department of Environmental Engineering and Science, Feng Chia University, Taichung, Taiwan, Republic of China
Ann Occup Hyg 52:177-85. 2008..This study aimed at determining the protection factors (PFs) provided by N95 filtering facepiece respirators and surgical masks against particles representing bacterial and viral size ranges (aerodynamic size: 0.04-1.3 mum)... - Personal exposures and microenvironmental concentrations of particles and bioaerosolsMika Toivola
National Public Health Institute, Division of Environmental Health, Kuopio, Finland
J Environ Monit 4:166-74. 2002..Our results indicate that personal exposure measurements of bioaerosols in indoor environments are feasible and supplement the information obtained by stationary samplers...