Affiliation: University of Michigan
- The chromatin remodelling factor BRG1 is a novel binding partner of the tumor suppressor p16INK4aTherese M Becker
Westmead Institute for Cancer Research, University of Sydney, Westmead Millennium Institute and Westmead Hospital, Australia
Mol Cancer 8:4. 2009..To identify such functions we conducted a yeast-two-hybrid screen for novel p16INK4a binding partners...
- The SWI/SNF complex and cancerD Reisman
Department of Internal Medicine, University of Michigan College of Medicine, Ann Arbor, MI 48109 0686, USA
Oncogene 28:1653-68. 2009....
- The reversible epigenetic silencing of BRM: implications for clinical targeted therapyS Glaros
Department of Internal Medicine, Division of Hematology Oncology, University of Michigan, Ann Arbor, MI, USA
Oncogene 26:7058-66. 2007..Thus, BRG1 and BRM are silenced by different mechanisms, and it may be possible to clinically target and reexpress BRM in a number of tumor types, potentially impacting tumor development...