D J Reinkensmeyer

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc The Resonating Arm Exerciser: design and pilot testing of a mechanically passive rehabilitation device that mimics robotic active assistance
    Daniel K Zondervan
    Department of Mechanical and Aerospace Engineering, University of California at Irvine, Irvine, USA
    J Neuroeng Rehabil 10:39. 2013
  2. pmc Recent trends in assistive technology for mobility
    Rachel E Cowan
    Department of Neurological Surgery, The Miami Project to Cure Paralysis, University of Miami Miller School of Medicine, 1095 NW 14th Terrace, Miami, FL 33136, USA
    J Neuroeng Rehabil 9:20. 2012
  3. pmc Personalized neuromusculoskeletal modeling to improve treatment of mobility impairments: a perspective from European research sites
    Benjamin J Fregly
    Department of Mechanical and Aerospace Engineering, University of Florida, 231 MAE A Building, PO Box 116250, Gainesville, FL 32611 6250, USA
    J Neuroeng Rehabil 9:18. 2012
  4. pmc A computational model of use-dependent motor recovery following a stroke: optimizing corticospinal activations via reinforcement learning can explain residual capacity and other strength recovery dynamics
    David J Reinkensmeyer
    Department of Anatomy and Neurobiology, University of California at Irvine, USA
    Neural Netw 29:60-9. 2012
  5. pmc Major trends in mobility technology research and development: overview of the results of the NSF-WTEC European study
    David J Reinkensmeyer
    Department of Mechanical and Aerospace Engineering, University of California, Irvine, CA 92697 3875, USA
    J Neuroeng Rehabil 9:22. 2012
  6. pmc Technologies and combination therapies for enhancing movement training for people with a disability
    David J Reinkensmeyer
    Department of Mechanical and Aerospace Engineering, University of California, 4200 Engineering Gateway, Irvine, CA 92697 3875, USA
    J Neuroeng Rehabil 9:17. 2012
  7. pmc Human-robot cooperative movement training: learning a novel sensory motor transformation during walking with robotic assistance-as-needed
    Jeremy L Emken
    Biomedical Engineering Department, University of California at Irvine, Irvine, CA, USA
    J Neuroeng Rehabil 4:8. 2007
  8. pmc Effect of visual distraction and auditory feedback on patient effort during robot-assisted movement training after stroke
    Riccardo Secoli
    Biomechatronic Lab, Department of Mechanical Engineering, University of California, 4200 Engineering Gateway, Irvine, CA 92697 3875, USA
    J Neuroeng Rehabil 8:21. 2011
  9. pmc Review of control strategies for robotic movement training after neurologic injury
    Laura Marchal-Crespo
    Department of Mechanical and Aerospace Engineering, University of California, Irvine, CA, USA
    J Neuroeng Rehabil 6:20. 2009
  10. pmc A robotic wheelchair trainer: design overview and a feasibility study
    Laura Marchal-Crespo
    Mechanical and Aerospace Engineering Department, University of California, Irvine, CA, USA
    J Neuroeng Rehabil 7:40. 2010

Collaborators

Detail Information

Publications54

  1. pmc The Resonating Arm Exerciser: design and pilot testing of a mechanically passive rehabilitation device that mimics robotic active assistance
    Daniel K Zondervan
    Department of Mechanical and Aerospace Engineering, University of California at Irvine, Irvine, USA
    J Neuroeng Rehabil 10:39. 2013
    ..This paper describes the design and pilot testing of a simple, mechanically passive device that provides robot-like assistance for active arm training using the principle of mechanical resonance...
  2. pmc Recent trends in assistive technology for mobility
    Rachel E Cowan
    Department of Neurological Surgery, The Miami Project to Cure Paralysis, University of Miami Miller School of Medicine, 1095 NW 14th Terrace, Miami, FL 33136, USA
    J Neuroeng Rehabil 9:20. 2012
    ..We provide an overview of these improvements in user-technology integration and discuss whether such improvements have the potential to be transformative for people with mobility impairments...
  3. pmc Personalized neuromusculoskeletal modeling to improve treatment of mobility impairments: a perspective from European research sites
    Benjamin J Fregly
    Department of Mechanical and Aerospace Engineering, University of Florida, 231 MAE A Building, PO Box 116250, Gainesville, FL 32611 6250, USA
    J Neuroeng Rehabil 9:18. 2012
    ..We conclude by summarizing recommendations for future research efforts that would allow personalized neuromusculoskeletal models to make the greatest impact possible on treatment design for mobility impairments...
  4. pmc A computational model of use-dependent motor recovery following a stroke: optimizing corticospinal activations via reinforcement learning can explain residual capacity and other strength recovery dynamics
    David J Reinkensmeyer
    Department of Anatomy and Neurobiology, University of California at Irvine, USA
    Neural Netw 29:60-9. 2012
    ....
  5. pmc Major trends in mobility technology research and development: overview of the results of the NSF-WTEC European study
    David J Reinkensmeyer
    Department of Mechanical and Aerospace Engineering, University of California, Irvine, CA 92697 3875, USA
    J Neuroeng Rehabil 9:22. 2012
    ..This commentary summarizes these trends, which are then described in detail in companion papers appearing in this special issue...
  6. pmc Technologies and combination therapies for enhancing movement training for people with a disability
    David J Reinkensmeyer
    Department of Mechanical and Aerospace Engineering, University of California, 4200 Engineering Gateway, Irvine, CA 92697 3875, USA
    J Neuroeng Rehabil 9:17. 2012
    ..Such combination therapies will likely involve complex interactions with motor training that must be understood in order to achieve the goal of eliminating severe motor impairment...
  7. pmc Human-robot cooperative movement training: learning a novel sensory motor transformation during walking with robotic assistance-as-needed
    Jeremy L Emken
    Biomedical Engineering Department, University of California at Irvine, Irvine, CA, USA
    J Neuroeng Rehabil 4:8. 2007
    ..These attempts are currently not based on computational models of motor learning...
  8. pmc Effect of visual distraction and auditory feedback on patient effort during robot-assisted movement training after stroke
    Riccardo Secoli
    Biomechatronic Lab, Department of Mechanical Engineering, University of California, 4200 Engineering Gateway, Irvine, CA 92697 3875, USA
    J Neuroeng Rehabil 8:21. 2011
    ..To better understand patient slacking, we studied the role of visual distraction and auditory feedback in modulating patient effort during a common robot-assisted tracking task...
  9. pmc Review of control strategies for robotic movement training after neurologic injury
    Laura Marchal-Crespo
    Department of Mechanical and Aerospace Engineering, University of California, Irvine, CA, USA
    J Neuroeng Rehabil 6:20. 2009
    ....
  10. pmc A robotic wheelchair trainer: design overview and a feasibility study
    Laura Marchal-Crespo
    Mechanical and Aerospace Engineering Department, University of California, Irvine, CA, USA
    J Neuroeng Rehabil 7:40. 2010
    ..Experiencing independent mobility is important for children with a severe movement disability, but learning to drive a powered wheelchair can be labor intensive, requiring hand-over-hand assistance from a skilled therapist...
  11. ncbi request reprint Tools for understanding and optimizing robotic gait training
    David J Reinkensmeyer
    Department of Mechanical and Aerospace Engineering, University of California UC Irvine, Irvine, CA 92697 3975, USA
    J Rehabil Res Dev 43:657-70. 2006
    ..Currently, we are developing a pneumatic robot designed to meet these specifications as it assists leg and pelvic motion of people with SCI...
  12. ncbi request reprint Automating arm movement training following severe stroke: functional exercises with quantitative feedback in a gravity-reduced environment
    Robert J Sanchez
    Department of Mechanical and Aerospace Engienering, University of California, Irvine, CA 92697 3975, USA
    IEEE Trans Neural Syst Rehabil Eng 14:378-89. 2006
    ..001). These results demonstrate the feasibility of automating upper-extremity rehabilitation therapy for people with severe stroke using passive gravity assistance, a grip sensor, and simple virtual reality software...
  13. pmc Can robots help the learning of skilled actions?
    David J Reinkensmeyer
    Department of Mechanical and Aerospace Engineering, University of California at Irvine, Irvine, CA 92697 3975, USA
    Exerc Sport Sci Rev 37:43-51. 2009
    ..Recent experiments from our laboratories show how robotic devices can temporarily alter task dynamics in ways that contribute to the motor learning experience, suggesting possible applications in rehabilitation and sports training...
  14. doi request reprint Slacking by the human motor system: computational models and implications for robotic orthoses
    David J Reinkensmeyer
    Department of Mechanical and Aerospace Engineering and Department of Biomedical Engineering, University of California at Irvine, CA 92617, USA
    Conf Proc IEEE Eng Med Biol Soc 2009:2129-32. 2009
    ..For assistive applications of robotic orthoses, slacking may allow the motor system to learn to take advantage of force amplification provided by an orthosis, with positive consequences for human energy efficiency...
  15. ncbi request reprint Directional control of reaching is preserved following mild/moderate stroke and stochastically constrained following severe stroke
    David J Reinkensmeyer
    Department of Physical Medicine and Rehabilitation, Northwestern University, Chicago, IL 60611, USA
    Exp Brain Res 143:525-30. 2002
    ....
  16. ncbi request reprint A computational model of human-robot load sharing during robot-assisted arm movement training after stroke
    David J Reinkensmeyer
    Department of Mechanical and Aerospace Engineering, University of California at Irvine, CA 92617 3975, USA
    Conf Proc IEEE Eng Med Biol Soc 2007:4019-23. 2007
    ..These results provide insight into the computational mechanisms of human motor adaptation during rehabilitation therapy, and provide a framework for optimizing robot-assisted therapy...
  17. ncbi request reprint Understanding and treating arm movement impairment after chronic brain injury: progress with the ARM guide
    D J Reinkensmeyer
    Department of Mechanical and Aerospace Engineering, Center for Biomedical Engineering, University of California at Irvine, 92697 3975, USA
    J Rehabil Res Dev 37:653-62. 2000
    ..Directions for future research regarding the efficacy and practicality of rehabilitators are discussed...
  18. ncbi request reprint Assessment of active and passive restraint during guided reaching after chronic brain injury
    D J Reinkensmeyer
    Department of Mechanical and Aerospace Engineering, University of California, Irvine, USA
    Ann Biomed Eng 27:805-14. 1999
    ..These results demonstrate the feasibility of mechatronic assessment of the causes of decreased functional movement, and could provide a basis for enhanced treatment planning and monitoring following brain injury...
  19. ncbi request reprint Mechatronic assessment of arm impairment after chronic brain injury
    D J Reinkensmeyer
    Department of Mechanical and Aerospace Engineering, University of California, Irvine 92697 3975, USA
    Technol Health Care 7:431-5. 1999
    ..These results demonstrate the feasibility of objective assessment of functional movement using a mechatronic device, and could provide the basis for improved, individualized treatment planning and monitoring following brain injury...
  20. ncbi request reprint Robotics, motor learning, and neurologic recovery
    David J Reinkensmeyer
    Department of Mechanical and Aerospace Engineering, University of California, Irvine, California 92697 3975, USA
    Annu Rev Biomed Eng 6:497-525. 2004
    ..In addition to providing insight into motor control, robotic paradigms may eventually enhance motor learning and rehabilitation beyond the levels possible with conventional training techniques...
  21. ncbi request reprint Web-based telerehabilitation for the upper extremity after stroke
    David J Reinkensmeyer
    Department of Mechanical and Aerospace Engineering, Center for Biomedical Engineering, University of California, Irvine 92697 3975, USA
    IEEE Trans Neural Syst Rehabil Eng 10:102-8. 2002
    ..Data from home-based usage by a chronic stroke subject are presented that demonstrate the feasibility of using the system to direct a therapy program, mechanically assist in movement, and track improvements in movement ability...
  22. ncbi request reprint Motor adaptation to a small force field superimposed on a large background force
    Jiayin Liu
    Department of Mechanical and Aerospace Engineering, University of California, Irvine, CA 92697 3975, USA
    Exp Brain Res 178:402-14. 2007
    ..Finally, these results suggest that computational models of motor adaptation will likely need to include force-dependent parameters to accurately predict errors...
  23. doi request reprint A randomized controlled trial of gravity-supported, computer-enhanced arm exercise for individuals with severe hemiparesis
    Sarah J Housman
    Sensory Motor Performance Program, Rehabilitation Institute of Chicago, Chicago, Illinois 60660, USA
    Neurorehabil Neural Repair 23:505-14. 2009
    ..The purpose of this study was to compare semiautonomous training with T-WREX and conventional semiautonomous exercises that used a tabletop for gravity support...
  24. doi request reprint Do robotic and non-robotic arm movement training drive motor recovery after stroke by a common neural mechanism? Experimental evidence and a computational model
    David J Reinkensmeyer
    Department of Mechanical and Aerospace Engineering, University of California, Irvine, CA 92697, USA
    Conf Proc IEEE Eng Med Biol Soc 2009:2439-41. 2009
    ..Robot-assisted and unassisted training would in theory equally drive this search process...
  25. ncbi request reprint Persistence of motor adaptation during constrained, multi-joint, arm movements
    R A Scheidt
    Department of Biomedical Engineering, Northwestern University, Evanston, IL 60622, USA
    J Neurophysiol 84:853-62. 2000
    ....
  26. ncbi request reprint Robot-assisted hindlimb extension increases the probability of swing initiation during treadmill walking by spinal cord contused rats
    Jeff A Nessler
    Department of Mechanical and Aerospace Engineering, Center for Biomedical Engineering, 4200 Engineering Gateway E3225, University of California, Irvine, CA 92697 3975, USA
    J Neurosci Methods 159:66-77. 2007
    ..These results indicate that a greater amount of stepping activity can be elicited by robot-assisted extension, thereby providing possible benefits to evaluation and training of gait following SCI...
  27. pmc Retraining the injured spinal cord
    V R Edgerton
    Brain Research Institute and Departments of Physiological Science and Neurobiology, University of California, Los Angeles, CA 90095, USA
    J Physiol 533:15-22. 2001
    ..These concepts and observations demonstrate that (a) the spinal cord can interpret complex afferent information and generate the appropriate motor task; and (b) motor ability can be defined to a large degree by training...
  28. ncbi request reprint The rat lumbosacral spinal cord adapts to robotic loading applied during stance
    W K Timoszyk
    Department of Mechanical and Aerospace Engineering and Center for Biomedical Engineering, University of California, Irvine, 92697 3975, California, USA
    J Neurophysiol 88:3108-17. 2002
    ....
  29. ncbi request reprint Control of a pneumatic orthosis for upper extremity stroke rehabilitation
    Eric T Wolbrecht
    Mech and Aerosp Eng Dept, Univ California, Irvine, CA 92697, USA
    Conf Proc IEEE Eng Med Biol Soc 1:2687-93. 2006
    ..Thus, the orthosis is a promising tool for upper extremity rehabilitation after stroke...
  30. ncbi request reprint Impedance control and internal model formation when reaching in a randomly varying dynamical environment
    C D Takahashi
    Department of Mechanical and Aerospace Engineering and Center for Biomedical Engineering, University of California, Irvine 92697-3975, USA
    J Neurophysiol 86:1047-51. 2001
    ....
  31. ncbi request reprint Hemiparetic stroke impairs anticipatory control of arm movement
    Craig D Takahashi
    Department of Mechanical and Aerospace Engineering, University of California, 4200 Engineering Gateway, Irvine, CA 92697 3975, USA
    Exp Brain Res 149:131-40. 2003
    ..Finding ways to fully restore this adaptive ability, or to make use of what adaptive ability remains during rehabilitation, is an important goal for improving functional motor recovery...
  32. ncbi request reprint Dynamic motion planning for the design of robotic gait rehabilitation
    Chia Yu E Wang
    Department of Mechanical and Aerospace Engineering, University of California, Irvine, California 92697, USA
    J Biomech Eng 127:672-9. 2005
    ..The resulting motions can be found at the web site http://ww.eng.uci.edu/-chwang/project/stepper/stepper.html...
  33. ncbi request reprint Robot-assisted movement training for the stroke-impaired arm: Does it matter what the robot does?
    Leonard E Kahn
    Sensory Motor Performance Program, Rehabilitation Institute of Chicago, Chicago, IL, USA
    J Rehabil Res Dev 43:619-30. 2006
    ..We describe the engineering implementation of this "guided-force training" algorithm...
  34. doi request reprint Comparison of error-amplification and haptic-guidance training techniques for learning of a timing-based motor task by healthy individuals
    Marie Hélène Milot
    Department of Mechanical and Aerospace Engineering, University of California, Irvine, 4200 Engineering Gateway, Irvine, CA 92697, USA
    Exp Brain Res 201:119-31. 2010
    ..These results suggest that both techniques help enhanced performance of a timing task, but learning is optimized if training subjects with the appropriate technique based on their baseline skill level...
  35. pmc The effect of haptic guidance, aging, and initial skill level on motor learning of a steering task
    Laura Marchal-Crespo
    Department of Mechanical and Aerospace Engineering, Henry Samueli School of Engineering, 4200 Engineering Gateway Building, Irvine, CA 92697 3975, USA
    Exp Brain Res 201:209-20. 2010
    ..This study demonstrates that training with haptic guidance can benefit long-term retention of a driving skill for young and for some old drivers. Training with haptic guidance is more useful for people with less initial skill...
  36. ncbi request reprint Robot-enhanced motor learning: accelerating internal model formation during locomotion by transient dynamic amplification
    Jeremy L Emken
    Biomedical Engineering Department, University of California Irvine, Irvine, CA 92697, USA
    IEEE Trans Neural Syst Rehabil Eng 13:33-9. 2005
    ..These results support an approach to movement training devices that amplify rather than reduce movement errors, and provide a computational framework for both implementing the approach and understanding its limitations...
  37. doi request reprint Haptic guidance can enhance motor learning of a steering task
    Laura Marchal Crespo
    Department of Mechanical and Aerospace Engineering, University of California Irvine, CA 92697, USA
    J Mot Behav 40:545-56. 2008
    ..However, this difference quickly dissipated with more practice. We conclude that haptic guidance can benefit short-term learning of a steering-type task while also limiting performance errors during training...
  38. ncbi request reprint Spinal cord-transected mice learn to step in response to quipazine treatment and robotic training
    Andy J Fong
    Biomedical Engineering Interdepartmental Program, University of California, Los Angeles, California 90095, USA
    J Neurosci 25:11738-47. 2005
    ..When administered intermittently during an extended period of robotic training, quipazine revealed training-induced stepping improvements that were masked in the absence of the pharmacological treatment...
  39. doi request reprint Feasibility of manual teach-and-replay and continuous impedance shaping for robotic locomotor training following spinal cord injury
    Jeremy L Emken
    Biomedical Engineering Department, University of California, Irvine, CA 92797, USA
    IEEE Trans Biomed Eng 55:322-34. 2008
    ..The result was that the subjects stepped with greater variability, while still maintaining a physiologic gait pattern. These results are further steps toward tailoring robotic gait training to the needs of individual patients...
  40. ncbi request reprint Quantification of therapists' manual assistance on the leg during treadmill gait training with partial body-weight support after spinal cord injury
    Jose A Galvez
    Department of Mechanical and Aerospace Engineering, University of California, Irvine, CA, USA
    Conf Proc IEEE Eng Med Biol Soc 2007:4028-32. 2007
    ..These results provide insight into therapist-assisted gait training, which may be useful for optimizing robotic gait-training devices...
  41. ncbi request reprint Robotic gait analysis of bipedal treadmill stepping by spinal contused rats: characterization of intrinsic recovery and comparison with BBB
    Jeff A Nessler
    Department of Mechanical and Aerospace Engineering, University of California, Irvine, California 92697 3975, USA
    J Neurotrauma 23:882-96. 2006
    ..Thus, by measuring only a few weight-supported steps with motion capture, a sensitive, valid measure of locomotor recovery following contusion injury can be obtained across a broad range of impairment levels...
  42. ncbi request reprint Modeling reaching impairment after stroke using a population vector model of movement control that incorporates neural firing-rate variability
    David J Reinkensmeyer
    Department of Mechanical and Aerospace Engineering and Center for Biomedical Engineering, University of California at Irvine, Irvine, CA 92697, USA
    Neural Comput 15:2619-42. 2003
    ....
  43. ncbi request reprint Hindlimb loading determines stepping quantity and quality following spinal cord transection
    Wojciech K Timoszyk
    Department of Mechanical and Aerospace Engineering, 4200 Engineering Gateway EG3225, University of California, Irvine, CA 92697 3975, USA
    Brain Res 1050:180-9. 2005
    ..Finally, load-bearing failure point can be a quantitative measure of locomotor recovery following spinal cord injury, especially for severely impaired animals that cannot step unassisted...
  44. ncbi request reprint Effect of muscle fatigue on internal model formation and retention during reaching with the arm
    Craig D Takahashi
    Dept of Mechanical and Aerospace Engineering, 4200 Engineering Gateway, Univ of California, Irvine, CA 92697 3975, USA
    J Appl Physiol 100:695-706. 2006
    ..Recovery from fatigue apparently affects recall because the motor system represents internal models as a mapping between effort and movement and relies on practice to recalibrate this mapping...
  45. ncbi request reprint Neuromotor noise limits motor performance, but not motor adaptation, in children
    Craig D Takahashi
    Department of Mechanical and Aerospace Engineering and Center for Biomedical Engineering, University of California, Irvine 92697 3975, USA
    J Neurophysiol 90:703-11. 2003
    ....
  46. ncbi request reprint Motor adaptation as a greedy optimization of error and effort
    Jeremy L Emken
    Mechanical and Aerospace Engineering Department, University of California, Irvine, California 92697 3975, USA
    J Neurophysiol 97:3997-4006. 2007
    ..We found however that the equation adequately captured the pattern of errors and thus conclude that motor adaptation to a force field can be approximated as an optimization of effort and error for a range of experimental conditions...
  47. ncbi request reprint Alterations in reaching after stroke and their relation to movement direction and impairment severity
    Derek G Kamper
    Sensory Motor Performance Program, Rehabilitation Institute of Chicago, Chicago, IL 60611, USA
    Arch Phys Med Rehabil 83:702-7. 2002
    ....
  48. ncbi request reprint Robotic assistance for upper extremity training after stroke
    David J Reinkensmeyer
    Department of Mechanical and Aerospace Engineering, University of California at Irvine, CA, USA
    Stud Health Technol Inform 145:25-39. 2009
    ..Future advances in the field will likely be driven by scientific studies focused on defining the behavioral factors that influence motor plasticity...
  49. ncbi request reprint Locomotor ability in spinal rats is dependent on the amount of activity imposed on the hindlimbs during treadmill training
    John Cha
    Department of Biological Science, California State University, Los Angeles, California 90032 8162, USA
    J Neurotrauma 24:1000-12. 2007
    ....
  50. ncbi request reprint A robot and control algorithm that can synchronously assist in naturalistic motion during body-weight-supported gait training following neurologic injury
    Daisuke Aoyagi
    Los Amigos Research and Education Institute, Downey, CA 90242, USA
    IEEE Trans Neural Syst Rehabil Eng 15:387-400. 2007
    ....
  51. ncbi request reprint A robotic device for studying rodent locomotion after spinal cord injury
    Jeff A Nessler
    Rehabilitation Institute of Chicago, IL 60610, USA
    IEEE Trans Neural Syst Rehabil Eng 13:497-506. 2005
    ..This paper provides a detailed description of the device design and a characterization of its robotic performance capabilities...
  52. ncbi request reprint Use of robotics in assessing the adaptive capacity of the rat lumbar spinal cord
    Ray D de Leon
    Department of Kinesiology and Nutritional Science, California State University, Los Angeles, CA 90032 8162, USA
    Prog Brain Res 137:141-9. 2002
    ....
  53. ncbi request reprint Using robotics to teach the spinal cord to walk
    Ray D de Leon
    Department of Kinesiology and Nutritional Science, California State University, 5151 State University Drive, Los Angeles, CA 90032, USA
    Brain Res Brain Res Rev 40:267-73. 2002
    ..These results suggest that critical elements for successful training of hindlimb stepping in spinal cord injured rats can be implemented rigorously and evaluated using the rat stepper...
  54. doi request reprint Optimizing compliant, model-based robotic assistance to promote neurorehabilitation
    Eric T Wolbrecht
    Mechanical Engineering Department, University of Idaho, Moscow, ID 83844, USA
    IEEE Trans Neural Syst Rehabil Eng 16:286-97. 2008
    ..The experiments also demonstrate how including the "assist-as-needed" modification in the controller increases participation from the motor system...