Research Topics
Species | Kaaren K ReichardSummaryAffiliation: University of New Mexico Country: USA Publications
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Publications
Pediatric B-lymphoblastic leukemia with RUNX1 amplification: clinicopathologic study of eight casesKaaren K Reichard
Department of Pathology, University of New Mexico, Health Sciences Center, Albuquerque, NM, USA
Mod Pathol 24:1606-11. 2011..Long-term follow-up in larger cohorts including minimal residual disease correlation is required...
ALK-positive diffuse large B-cell lymphoma: report of four cases and review of the literatureKaaren K Reichard
Department of Pathology, University of New Mexico, Albuquerque, NM 87131, USA
Mod Pathol 20:310-9. 2007..After CHOP and radiotherapy, two stage I patients were free of disease at 58 and 36 months, whereas a stage IV patient was dead of disease at 22 months...
CD10 expression in peripheral T-cell lymphomas complicated by a proliferation of large B-cellsKaaren K Reichard
Department of Pathology, Stanford University Medical Center, Stanford, CA, USA
Mod Pathol 19:337-43. 2006..57 (Fisher's exact test). As these entities appear to be biologically distinct and may portend different overall survivals, CD10 expression may serve as an additional discriminating criterion...
Acute myeloid leukemia of donor origin after allogeneic bone marrow transplantation for precursor T-cell acute lymphoblastic leukemia: case report and review of the literatureKaaren K Reichard
Department of Pathology, University of New Mexico, Albuquerque, 87131, USA
Am J Hematol 81:178-85. 2006..Donor-cell leukemia (DCL) after allogeneic BMT is a rare, yet well-documented, event. Our report presents clinicopathologic information about a case of DCL and a review of the recent literature...
Automated analysis of fluorescence in situ hybridization on fixed, paraffin-embedded whole tissue sections in B-cell lymphomaKaaren K Reichard
Department of Pathology, University of New Mexico, Albuquerque, 87131, USA
Mod Pathol 19:1027-33. 2006..Based on these results, automated analysis of fluorescence in situ hybridization on fixed tissues is accurate and valuable in the evaluation of B-cell lymphoma, and may provide pertinent diagnostic and prognostic information...
Clonal cytogenetic abnormalities in the plasma cell variant of Castleman diseaseKaaren K Reichard
Department of Pathology, University of New Mexico, Albuquerque, USA
Cancer Genet 204:323-7. 2011..Because the pathogenesis of PC-CD is not thought to typically involve the proliferation of these cell types, this is a new and unexpected finding and may provide pathogenetic insight...
Most morphologic features in chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) do not reliably predict underlying FISH genetics or immunoglobulin heavy chain variable region somatic mutational statusChristine F Garcia
Department of Pathology, University of Pittsburgh, Pittsburgh, PA, USA
Appl Immunohistochem Mol Morphol 18:119-27. 2010..In conclusion, morphologic features in SLL are not a reliable predictor of underlying genetic status. Thus, we propose a practical, cost-effective approach to the work-up of these cases, which should be driven by clinical necessity...
A double-positive CD4+CD8+ T-cell population is commonly found in nodular lymphocyte predominant Hodgkin lymphomaAliyah Rahemtullah
Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
Am J Clin Pathol 126:805-14. 2006..This population may be a clue to the diagnosis of NLPHL, particularly in cases with limited tissue...
Translocations involving MUM1 are rare in diffuse large B-cell lymphomaKristin E Hunt
Department of Pathology, University of New Mexico, Albuquerque, NM 87102, USA
Appl Immunohistochem Mol Morphol 18:109-12. 2010..We conclude that genetic abnormalities involving MUM1 are rare in DLBCL and that a mechanism of deregulation of the MUM1 protein other than by a translocation event is involved in the majority of non-GC cases...
Comparative analysis of light chain expression in germinal center cells and mantle cells of reactive lymphoid tissues. A four-color flow cytometric studyKaaren K Reichard
Department of Pathology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75930-9072, USA
Am J Clin Pathol 119:130-6. 2003..LCRs of GCCs and MCs may differ substantially in reactive lymphoid tissues. These subsets may form distinct clusters and skews in their LCRs and should not be misinterpreted as evidence of occult lymphoma...
t(9;22)(q34;q11.2) is a recurrent constitutional non-Robertsonian translocation and a rare cytogenetic mimic of chronic myeloid leukemiaDavid R Czuchlewski
Department of Pathology, University of New Mexico, Albuquerque, NM, USA
Cancer Genet 204:572-6. 2011..Our case underscores the necessity of complete clinical and laboratory correlation to avoid misdiagnosis of myeloid malignancy in the setting of rare constitutional cytogenetic abnormalities...
CD163: a specific immunohistochemical marker for acute myeloid leukemia with monocytic differentiationChristine Garcia
Department of Pathology, University of New Mexico, Albuquerque, NM 87131, USA
Appl Immunohistochem Mol Morphol 16:417-21. 2008..These findings demonstrate that CD163 is helpful for the evaluation of a monocytic component in AML. When positive, correlation and evaluation for an associated recurring cytogenetic abnormality is warranted...
CD4(+) CD56(+) lineage-negative malignancies are rare tumors of plasmacytoid dendritic cellsKaaren K Reichard
Department of Pathology, University of New Mexico, 2325 Camino de Salud, Albuquerque, NM 87112, USA
Am J Surg Pathol 29:1274-83. 2005..Furthermore, these rare neoplasms can be readily diagnosed using recently developed immunoperoxidase techniques...
Fluorescence in situ hybridization testing for -5/5q, -7/7q, +8, and del(20q) in primary myelodysplastic syndrome correlates with conventional cytogenetics in the setting of an adequate studyClovis W Pitchford
Department of Pathology, University of New Mexico Health Sciences Center, Albuquerque, NM, USA
Am J Clin Pathol 133:260-4. 2010..FISH for MDS abnormalities (-5/5q, -7/7q, +8, and del(20q)) correlates with an adequate karyotypic result without increased sensitivity. Consequently, we recommend that FISH not be performed in MDS cases with an adequate karyotype...
Immunophenotypic analysis of myeloperoxidase-negative leukemia cutis and blastic plasmacytoid dendritic cell neoplasmDanielle M P Cronin
Department of Pathology, Stanford University, Stanford, CA 94305, USA
Am J Clin Pathol 137:367-76. 2012..It is interesting that CD33 was not helpful; it stained 18 (78%) cases of LC and 11 cases (92%) of BPDCN. Our results indicate that a panel that includes CD4, CD56, CD123, and Tcl-1 can appropriately distinguish between these 2 entities...
Diffuse large B-cell lymphomaKristin E Hunt
University of New Mexico, Department of Pathology, Albuquerque, NM 87131, USA
Arch Pathol Lab Med 132:118-24. 2008..This short review covers the current clinical, morphologic, immunophenotypic, genetic, gene expression profiling, and prognostic (studies before and after the addition of rituximab) features of de novo diffuse large B-cell lymphoma...
Risk for leukemia in infants without Down syndrome who have transient myeloproliferative disorderThomas Cushing
Department of Pediatrics, Division of Genetics and Metabolism, Stanford University Medical Center, Stanford, California, USA
J Pediatr 148:687-9. 2006..We recommend that nondysmorphic infants with TMD undergo chromosome analysis for trisomy 21 and testing for GATA1 mutations to aid surveillance for leukemic transformation...
Novel markers of normal and neoplastic human plasmacytoid dendritic cellsTeresa Marafioti
Leukaemia Research Fund Immunodiagnostics Unit, Nuffield Department of Clinical Laboratory Sciences, John Radcliffe Hospital, Oxford, UK
Blood 111:3778-92. 2008....
