William F Regine

Summary

Affiliation: University of Maryland
Country: USA

Publications

  1. pmc Fluorouracil-based chemoradiation with either gemcitabine or fluorouracil chemotherapy after resection of pancreatic adenocarcinoma: 5-year analysis of the U.S. Intergroup/RTOG 9704 phase III trial
    William F Regine
    Department of Radiation Oncology, University of Maryland, Baltimore, MD, USA
    Ann Surg Oncol 18:1319-26. 2011
  2. doi request reprint Fluorouracil vs gemcitabine chemotherapy before and after fluorouracil-based chemoradiation following resection of pancreatic adenocarcinoma: a randomized controlled trial
    William F Regine
    Department of Radiation Oncology, University of Maryland Medical Center, Baltimore 21030, USA
    JAMA 299:1019-26. 2008
  3. ncbi request reprint Recursive partitioning analysis classifications I and II: applicability evaluated in a randomized trial for resected single brain metastases
    William F Regine
    Department of Radiation Medicine, University of Kentucky, Lexington, Kentucky, USA
    Am J Clin Oncol 27:505-9. 2004
  4. ncbi request reprint Adjuvant therapy for pancreatic cancer: current status, future directions
    William F Regine
    Department of Radiation Oncology, University of Maryland Medical Center, Baltimore MD 21201, USA
    Semin Oncol 33:S10-3. 2006
  5. ncbi request reprint Low-dose radiotherapy as a chemopotentiator of gemcitabine in tumors of the pancreas or small bowel: a phase I study exploring a new treatment paradigm
    William F Regine
    Department of Radiation Oncology, University of Maryland, Baltimore, MD, USA
    Int J Radiat Oncol Biol Phys 68:172-7. 2007
  6. ncbi request reprint Long-term results of hyperfractionated radiation and high-dose intraarterial cisplatin for unresectable oropharyngeal carcinoma
    Paul M Spring
    Division of Otolaryngology Head and Neck Surgery, University of Kentucky Chandler Medical Center, Lexington, Kentucky, USA
    Cancer 104:1765-71. 2005
  7. pmc Failure to adhere to protocol specified radiation therapy guidelines was associated with decreased survival in RTOG 9704--a phase III trial of adjuvant chemotherapy and chemoradiotherapy for patients with resected adenocarcinoma of the pancreas
    Ross A Abrams
    Department of Radiation Oncology, Rush University Medical Center, Chicago, IL 60612, USA
    Int J Radiat Oncol Biol Phys 82:809-16. 2012
  8. ncbi request reprint Long-term survival in patients with synchronous, solitary brain metastasis from non-small-cell lung cancer treated with radiosurgery
    Todd W Flannery
    Department of Radiation Oncology, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Int J Radiat Oncol Biol Phys 72:19-23. 2008
  9. ncbi request reprint A phase II study of concomitant hyperfractionated radiation therapy and double dose intra-arterial cisplatin for squamous cell carcinoma of the head and neck
    William F Regine
    University of Kentucky, Department of Radiation Medicine, 800 Rose Street, Lexington, KY 40536 0293, USA
    Technol Cancer Res Treat 1:133-40. 2002
  10. pmc Phase II study of bevacizumab with concurrent capecitabine and radiation followed by maintenance gemcitabine and bevacizumab for locally advanced pancreatic cancer: Radiation Therapy Oncology Group RTOG 0411
    Christopher H Crane
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
    J Clin Oncol 27:4096-102. 2009

Detail Information

Publications60

  1. pmc Fluorouracil-based chemoradiation with either gemcitabine or fluorouracil chemotherapy after resection of pancreatic adenocarcinoma: 5-year analysis of the U.S. Intergroup/RTOG 9704 phase III trial
    William F Regine
    Department of Radiation Oncology, University of Maryland, Baltimore, MD, USA
    Ann Surg Oncol 18:1319-26. 2011
    ..The impact of the addition of gemcitabine to 5-fluorouracil (5-FU) chemoradiation (CRT) on 5-year overall survival (OS) in resected pancreatic adenocarcinoma are presented with updated results of a phase III trial...
  2. doi request reprint Fluorouracil vs gemcitabine chemotherapy before and after fluorouracil-based chemoradiation following resection of pancreatic adenocarcinoma: a randomized controlled trial
    William F Regine
    Department of Radiation Oncology, University of Maryland Medical Center, Baltimore 21030, USA
    JAMA 299:1019-26. 2008
    ..Among patients with locally advanced metastatic pancreatic adenocarcinoma, gemcitabine has been shown to improve outcomes compared with fluorouracil...
  3. ncbi request reprint Recursive partitioning analysis classifications I and II: applicability evaluated in a randomized trial for resected single brain metastases
    William F Regine
    Department of Radiation Medicine, University of Kentucky, Lexington, Kentucky, USA
    Am J Clin Oncol 27:505-9. 2004
    ..An analysis of a previously published randomized trial was performed to determine the applicability of these RPA prognostic classes in the setting of resection of single metastases to the brain...
  4. ncbi request reprint Adjuvant therapy for pancreatic cancer: current status, future directions
    William F Regine
    Department of Radiation Oncology, University of Maryland Medical Center, Baltimore MD 21201, USA
    Semin Oncol 33:S10-3. 2006
    ..Just cause for optimism exists, but much work remains to be done. New adjuvant therapies need to be developed and tested, in carefully designed, well-executed, efficient clinical trials...
  5. ncbi request reprint Low-dose radiotherapy as a chemopotentiator of gemcitabine in tumors of the pancreas or small bowel: a phase I study exploring a new treatment paradigm
    William F Regine
    Department of Radiation Oncology, University of Maryland, Baltimore, MD, USA
    Int J Radiat Oncol Biol Phys 68:172-7. 2007
    ..To determine the maximum tolerated dose of upper abdominal low-dose fractionated radiotherapy (<1.0 Gy per fraction) given in combination with, and as a chemopotentiator for, gemcitabine...
  6. ncbi request reprint Long-term results of hyperfractionated radiation and high-dose intraarterial cisplatin for unresectable oropharyngeal carcinoma
    Paul M Spring
    Division of Otolaryngology Head and Neck Surgery, University of Kentucky Chandler Medical Center, Lexington, Kentucky, USA
    Cancer 104:1765-71. 2005
    ....
  7. pmc Failure to adhere to protocol specified radiation therapy guidelines was associated with decreased survival in RTOG 9704--a phase III trial of adjuvant chemotherapy and chemoradiotherapy for patients with resected adenocarcinoma of the pancreas
    Ross A Abrams
    Department of Radiation Oncology, Rush University Medical Center, Chicago, IL 60612, USA
    Int J Radiat Oncol Biol Phys 82:809-16. 2012
    ..5FU-RT treatment was preceded and followed by randomly assigned chemotherapy, either 5-FU or gemcitabine. This analysis explored whether failure to adhere to specified RT guidelines influenced survival and/or toxicity...
  8. ncbi request reprint Long-term survival in patients with synchronous, solitary brain metastasis from non-small-cell lung cancer treated with radiosurgery
    Todd W Flannery
    Department of Radiation Oncology, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Int J Radiat Oncol Biol Phys 72:19-23. 2008
    ..To report the outcome of patients with synchronous, solitary brain metastasis from non-small-cell lung cancer (NSCLC) treated with gamma knife stereotactic radiosurgery (GKSRS)...
  9. ncbi request reprint A phase II study of concomitant hyperfractionated radiation therapy and double dose intra-arterial cisplatin for squamous cell carcinoma of the head and neck
    William F Regine
    University of Kentucky, Department of Radiation Medicine, 800 Rose Street, Lexington, KY 40536 0293, USA
    Technol Cancer Res Treat 1:133-40. 2002
    ..Future investigation of this novel treatment strategy utilizing modern angiographic catheter/microcatherter technology will involve a single dose of IA cisplatin with HFX-RT and dose intensification using neoadjuvant therapy...
  10. pmc Phase II study of bevacizumab with concurrent capecitabine and radiation followed by maintenance gemcitabine and bevacizumab for locally advanced pancreatic cancer: Radiation Therapy Oncology Group RTOG 0411
    Christopher H Crane
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
    J Clin Oncol 27:4096-102. 2009
    ..Secondary end points were toxicity, progression-free survival (PFS), and response rate (RR)...
  11. pmc The influence of total nodes examined, number of positive nodes, and lymph node ratio on survival after surgical resection and adjuvant chemoradiation for pancreatic cancer: a secondary analysis of RTOG 9704
    Timothy N Showalter
    Department of Radiation Oncology, Jefferson Medical College, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Int J Radiat Oncol Biol Phys 81:1328-35. 2011
    ....
  12. ncbi request reprint Clinical research in pancreatic cancer: the Radiation Therapy Oncology Group trials
    Christopher G Willett
    Department of Radiation Oncology, Massachusetts General Hospital, Boston, MA 02114, USA
    Int J Radiat Oncol Biol Phys 56:31-7. 2003
    ..This report summarizes current and future Radiation Therapy Oncology Group clinical trials in the treatment of patients with localized pancreatic cancer...
  13. pmc Analysis of local control in patients receiving IMRT for resected pancreatic cancers
    Susannah Yovino
    Marlene and Stewart Greenebaum Cancer Center, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Int J Radiat Oncol Biol Phys 83:916-20. 2012
    ..A concern regarding this technique is the potential for geographic miss and decreased local control. We analyzed patterns of first failure among patients treated with IMRT for resected pancreatic cancer...
  14. doi request reprint Comparative analysis of the post-lumpectomy target volume versus the use of pre-lumpectomy tumor volume for early-stage breast cancer: implications for the future
    Elizabeth M Nichols
    Department of Radiation Oncology, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Int J Radiat Oncol Biol Phys 77:197-202. 2010
    ..Use of PTVs based on the pre-LPC might also result in greater patient eligibility for APBI-3D-CRT...
  15. doi request reprint Audio-visual biofeedback does not improve the reliability of target delineation using maximum intensity projection in 4-dimensional computed tomography radiation therapy planning
    Wei Lu
    Department of Radiation Oncology, University of Maryland School of Medicine, Baltimore, Maryland Electronic address
    Int J Radiat Oncol Biol Phys 88:229-35. 2014
    ....
  16. doi request reprint Dosimetric and geometric evaluation of a novel stereotactic radiotherapy device for breast cancer: the GammaPod™
    Yildirim D Mutaf
    Department of Radiation Oncology, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
    Med Phys 40:041722. 2013
    ..This study presents the first evaluation of dosimetric and geometric characteristics from the initial prototype installed at University of Maryland Radiation Oncology Department...
  17. ncbi request reprint Spatially fractionated GRID radiation treatment of advanced neck disease associated with head and neck cancer
    Jeniffer L Huhn
    University of Kentucky, 800 Rose St N15, Lexington, KY 40536, USA
    Technol Cancer Res Treat 5:607-12. 2006
    ..It may improve pathologic complete response rates in those patients who undergo planned neck dissection, possibly leading to improved survival. In patients with inoperable bulky disease, addition of GRID enhances local-regional control...
  18. ncbi request reprint Stereotatic radiosurgery of 468 brain metastases < or =2 cm: implications for SRS dose and whole brain radiation therapy
    Michael K Shehata
    Department of Radiation Medicine, University of Kentucky, Lexington, KY, USA
    Int J Radiat Oncol Biol Phys 59:87-93. 2004
    ..On the basis of our institutional experience, the goal of this study was to determine the optimal SRS dose and influence of WBRT on local tumor control among 468 < or =2-cm metastases...
  19. doi request reprint High-dose spatially fractionated GRID radiation therapy (SFGRT): a comparison of treatment outcomes with Cerrobend vs. MLC SFGRT
    Geoffrey Neuner
    Department of Radiation Oncology, University of Maryland School of Medicine, Baltimore, MD, USA
    Int J Radiat Oncol Biol Phys 82:1642-9. 2012
    ..The clinical efficacy of our own multileaf collimator (MLC) technique is unknown. We undertook a retrospective analysis to compare clinical response rates attained using these two techniques...
  20. ncbi request reprint Low-dose fractionated radiation potentiates the effects of Paclitaxel in wild-type and mutant p53 head and neck tumor cell lines
    Swatee Dey
    Department of Radiation Medicine, College of Medicine, University of Kentucky, Lexington, Kentucky 40536, USA
    Clin Cancer Res 9:1557-65. 2003
    ..These findings strongly suggest that LDFRT (at these doses, HRS phenomenon is observed) can be used in combination with Paclitaxel to overcome the antiapoptotic effects of BCL-2 and nuclear factor kappa B...
  21. doi request reprint Preoperative radiation therapy significantly increases patient eligibility for accelerated partial breast irradiation using 3D-conformal radiotherapy
    Elizabeth M Nichols
    Department of Radiation Oncology, University of Maryland, South Greene St, Baltimore, MD, USA
    Am J Clin Oncol 36:232-8. 2013
    ..Administration of APBI-3D-CRT in the preoperative (preop) setting has been shown to decrease the planning target volume. The impact of this decrease on patient eligibility for APBI has not been evaluated in a comparative manner...
  22. doi request reprint Intensity-modulated radiation therapy significantly improves acute gastrointestinal toxicity in pancreatic and ampullary cancers
    Susannah Yovino
    Department of Radiation Oncology, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Int J Radiat Oncol Biol Phys 79:158-62. 2011
    ..Whether these improved dose distributions are associated with decreased toxicity when compared with conventional three-dimensional treatment remains a subject of investigation...
  23. ncbi request reprint The use of gated and 4D CT imaging in planning for stereotactic body radiation therapy
    WARREN D D'SOUZA
    Department of Radiation Oncology, University of Maryland School of Medicine, Baltimore, MD, USA
    Med Dosim 32:92-101. 2007
    ..Our results show that patient-specific target definition using gated or 4D CT scans lead to improved normal tissue sparing...
  24. ncbi request reprint Direct decompressive surgical resection in the treatment of spinal cord compression caused by metastatic cancer: a randomised trial
    Roy A Patchell
    Department of Surgery Neurosurgery, University of Kentucky Medical Center, Lexington, KY 40536, USA
    Lancet 366:643-8. 2005
    ..The standard treatment for spinal cord compression caused by metastatic cancer is corticosteroids and radiotherapy. The role of surgery has not been established. We assessed the efficacy of direct decompressive surgery...
  25. ncbi request reprint Effects of tumor motion in GRID therapy
    Shahid A Naqvi
    Radiation Oncology, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
    Med Phys 35:4435-42. 2008
    ....
  26. ncbi request reprint Oral/pharyngeal squamous carcinoma: treatment strategies
    Daniel E Kenady
    Department of Surgery, University of Kentucky College of Medicine, Markey Cancer Center, Lexington, Kentucky, USA
    J Ky Med Assoc 100:488-94. 2002
    ..In advanced disease neither surgery nor radiation therapy can be used as a primary modality, and often combined treatment is necessary. Chemotherapy has a less well-defined role, but is increasing control rates in advanced tumors...
  27. ncbi request reprint The evolving role of postoperative adjuvant radiation therapy for pancreatic cancer
    Michael C Garofalo
    Department of Radiation Oncology, University of Maryland at Baltimore, 22 South Green Street, Baltimore, MD 21201, USA
    Surg Oncol Clin N Am 13:589-604, viii. 2004
    ..Implications of the recently completed intergroup study are discussed, modern radiation therapy delivery techniques are reviewed, and suggestions for future trials are made...
  28. doi request reprint Factors impacting volumetric white matter changes following whole brain radiation therapy
    Nicholas Szerlip
    Department of Neurosurgery, University of Maryland Medical Center, Baltimore, MD, USA
    J Neurooncol 103:111-9. 2011
    ..This has significant clinical impact by clearly identifying hyperglycemia, steroid-induced hyperglycemia, and other vascular risk factors as targets for intervention to decrease WMC in patients receiving WBRT...
  29. ncbi request reprint A multi-institutional review of radiosurgery alone vs. radiosurgery with whole brain radiotherapy as the initial management of brain metastases
    Penny K Sneed
    Department of Radiation Oncology, University of California San Francisco, 505 Parnassus Avenue, San Francisco, CA 94143 0226, USA
    Int J Radiat Oncol Biol Phys 53:519-26. 2002
    ..Data collected from 10 institutions were reviewed to compare survival probabilities of patients with newly diagnosed brain metastases managed initially with radiosurgery (RS) alone vs. RS + whole brain radiotherapy (WBRT)...
  30. ncbi request reprint Concurrent infusional gemcitabine and radiation in the treatment of advanced unresectable GI malignancy: a phase I study
    Mohammed Mohiuddin
    Department of Radiation Medicine, University of Kentucky, Lexington 40536 0293, USA
    Cancer J 8:255-62. 2002
    ..A phase I/II study was undertaken to establish the maximum tolerated dose of infusional gemcitabine when combined with radiation therapy in advanced gastrointestinal malignancies and to assess the response to treatment...
  31. ncbi request reprint Neurologic complications of bladder carcinoma: a review of 359 cases
    Thomas S Anderson
    Department of Surgery, Neurosurgery Division, University of Kentucky Medical Center, Lexington, Kentucky 40536, USA
    Cancer 97:2267-72. 2003
    ..In the current study, the authors reviewed a large series of patients to determine the nature and frequency of neurologic complications...
  32. ncbi request reprint A phase I trial of the dual farnesyltransferase and geranylgeranyltransferase inhibitor L-778,123 and radiotherapy for locally advanced pancreatic cancer
    Neil E Martin
    Department of Radiation Oncology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    Clin Cancer Res 10:5447-54. 2004
    ....
  33. ncbi request reprint The radiation oncologist's perspective on stereotactic radiosurgery
    William F Regine
    University of Kentucky, Department of Radiation Medicine, 800 Rose Street, Lexington KY 40536 0293, USA
    Technol Cancer Res Treat 1:43-9. 2002
    ..Details of these studies, along with others, will be reviewed and implications with regards to the complementary role of WBRT in patients undergoing SRS for brain metastases will be discussed...
  34. ncbi request reprint Cancer caregiving and subjective stress: a multi-site, multi-dimensional analysis
    Joseph E Gaugler
    Department of Behavioral Science, College of Medicine, The University of Kentucky, Lexington, KY 40536, USA
    Psychooncology 14:771-85. 2005
    ..The findings offer a number of recommendations for future research and practice focused on informal cancer care...
  35. ncbi request reprint The rationale for adjuvant whole brain radiation therapy with radiosurgery in the treatment of single brain metastases
    Roy A Patchell
    Neurosurgery Division, University of Kentucky Medical Center, 800 Rose Street, Lexington, KY 40536, USA
    Technol Cancer Res Treat 2:111-5. 2003
    ..This paper examines the scientific evidence and the arguments, pro and con, concerning the use of adjuvant WBRT in association with stereotactic radiosurgery or conventional surgery...
  36. ncbi request reprint Feasibility of delivering grid therapy using a multileaf collimator
    Jonathan K Ha
    Radiation Oncology, University of Maryland, Baltimore, Maryland 21201, USA
    Med Phys 33:76-82. 2006
    ..The results clearly showed that MLCs can be used to provide grid treatments with at least as good dosimetric properties as those of the Cerrobend grid blocks, though the former would in general require a longer delivery time...
  37. ncbi request reprint Gamma knife stereotactic radiosurgery for synchronous versus metachronous solitary brain metastases from non-small cell lung cancer
    Todd W Flannery
    Department of Radiation Oncology, University of Maryland School of Medicine, 22 South Greene Street, Baltimore, MD 21201, USA
    Lung Cancer 42:327-33. 2003
    ..This study adds to the growing body of literature that supports the use of SRS in the management of this patient population...
  38. ncbi request reprint Concomitant GRID boost for Gamma Knife radiosurgery
    Lijun Ma
    Department of Radiation Oncology, University of Maryland School of Medicine, Baltimore, Maryland 21210, USA
    Med Phys 32:3419-23. 2005
    ..e., the near region) were decreased for the GRID boost technique. In conclusion, we demonstrated a new technique for Gamma Knife radiosurgery that can escalate the dose to the target while sparing the adjacent normal brain tissue...
  39. ncbi request reprint The impact of TNF-alpha induction on therapeutic efficacy following high dose spatially fractionated (GRID) radiation
    Sabapathi Sathishkumar
    University of Kentucky, Department of Radiation Medicine, 800 Rose Street, Lexington, KY 40536 0293, USA
    Technol Cancer Res Treat 1:141-7. 2002
    ..Complete tumor response strongly correlated with the induction of TNF-alpha levels in the serum...
  40. doi request reprint Increasing national mastectomy rates for the treatment of early stage breast cancer
    Usama Mahmood
    Department of Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA
    Ann Surg Oncol 20:1436-43. 2013
    ..To study national trends in the mastectomy rate for treatment of early stage breast cancer...
  41. doi request reprint Investigation of motion sickness and inertial stability on a moving couch for intra-fraction motion compensation
    WARREN D D'SOUZA
    Department of Radiation Oncology, University of Maryland School of Medicine, Baltimore, MD, 21201, USA
    Acta Oncol 48:1198-203. 2009
    ..Our results show that patients do not suffer motion sickness or external surface instability on a moving couch...
  42. ncbi request reprint Long-term outcomes of Gamma Knife radiosurgery for classic trigeminal neuralgia: implications of treatment and critical review of the literature. Clinical article
    Anil A Dhople
    Department of Radiation Oncology, University of Maryland School of Medicine, 22 South Greene Street, Baltimore, Maryland 21201, USA
    J Neurosurg 111:351-8. 2009
    ..The authors report their long-term experience with the use of GKS in a previously reported cohort of patients with TN that has now been followed since 1996...
  43. ncbi request reprint Risk of symptomatic brain tumor recurrence and neurologic deficit after radiosurgery alone in patients with newly diagnosed brain metastases: results and implications
    William F Regine
    Department of Radiation Medicine, University of Kentucky, Lexington, KY 40536 0084, USA
    Int J Radiat Oncol Biol Phys 52:333-8. 2002
    ....
  44. ncbi request reprint Factors predicting local tumor control after gamma knife stereotactic radiosurgery for benign intracranial meningiomas
    Steven J DiBiase
    Department of Radiation Oncology, Cooper University Hospital, Camden, NJ 08103, USA
    Int J Radiat Oncol Biol Phys 60:1515-9. 2004
    ..To determine the long-term outcomes and prognostic factors in benign intracranial meningiomas treated with gamma knife stereotactic radiosurgery (GK-SRS)...
  45. ncbi request reprint Stereotactic radiosurgery for meningiomas
    Lawrence S Chin
    Department of Neurosurgery, University of Maryland School of Medicine, Baltimore, Maryland, USA
    Neurosurg Focus 14:e6. 2003
    ..Radiosurgery is an excellent treatment for asymptomatic, small- to moderate-sized meningiomas. It is also ideal for patients with incompletely resected meningiomas, recurrent meningiomas, and risk factors precluding conventional surgery...
  46. ncbi request reprint Spinal cord and peripheral nerve injury: current management and investigations
    William H St Clair
    Department of Radiation Medicine, University of Kentucky, Lexington, KY, USA
    Semin Radiat Oncol 13:322-32. 2003
    ..This review presents current management and investigations associated with these modality-related injuries...
  47. ncbi request reprint Gamma knife surgery for trigeminal neuralgia: outcome, imaging, and brainstem correlates
    Alice V Cheuk
    University of Maryland School of Medicine, Baltimore, MD, USA
    Int J Radiat Oncol Biol Phys 60:537-41. 2004
    ....
  48. ncbi request reprint Interval pathologic assessments in patients treated with concurrent hyperfractionated radiation and intraarterial cisplatin (HYPERRADPLAT)
    Joseph Valentino
    Division of Otolaryngology, University of Kentucky, Chandler Medical Center, Veterans Administration Hospital, Lexington, Kentucky 40536 0293, USA
    Head Neck 24:539-44. 2002
    ..These assumptions regarding head and neck cancer in patients treated with concurrent hyperfractionated radiation therapy and intraarterial supradose cisplatin (HYPERRADPLAT) have never been evaluated...
  49. ncbi request reprint Feasibility of neurocognitive outcome evaluations in patients with brain metastases in a multi-institutional cooperative group setting: results of Radiation Therapy Oncology Group trial BR-0018
    William F Regine
    Department of Radiation Oncology, University of Maryland Medical System, Baltimore, MD 21201, USA
    Int J Radiat Oncol Biol Phys 58:1346-52. 2004
    ....
  50. pmc Optimal adjuvant therapy for resected pancreatic cancer: chemotherapy or chemoradiotherapy?
    Michael C Garofalo
    Department of Radiation Oncology, University of Maryland School of Medicine, Baltimore, MD
    Gastrointest Cancer Res 1:182-7. 2007
    ..It is suggested that (1) patients do benefit from adjuvant therapy, and (2) optimal adjuvant therapy should include gemcitabine-based chemoradiotherapy for select patient subgroups...
  51. doi request reprint ACR Appropriateness Criteria on resectable rectal cancer: expert panel on radiation oncology--rectal/anal cancer
    W Warren Suh
    Department of Radiation Oncology, Dana Farber Cancer Institute Brigham and Women s Hospital, Boston, MA 02459, USA
    Int J Radiat Oncol Biol Phys 70:1427-30. 2008
    ..A summary of the major randomized clinical trials spanning the past several decades is provided...
  52. doi request reprint Utilization of intensity-modulated radiation therapy and image-guided radiation therapy in pancreatic cancer: is it beneficial?
    Adam S Reese
    Department of Radiation Oncology, University of Maryland Medical Center, Baltimore, Md Electronic address
    Semin Radiat Oncol 24:132-9. 2014
    ..Here, we review published data and provide essential recommendations on the utilization of IMRT and IGRT for the management of patients with pancreatic cancer. ..
  53. doi request reprint Complete resolution of laryngeal amyloidosis with radiation treatment
    Geoffrey A Neuner
    Department of Radiation Oncology, University of Maryland Medical Center, Baltimore, Maryland, USA
    Head Neck 34:748-52. 2012
    ..Localized amyloidosis of the larynx is a rare entity of unclear etiology. Surgical debulking is the primary treatment modality but often is not curative...
  54. ncbi request reprint Radiation therapy alone for spinal cord compression: time to improve upon a relatively ineffective status quo
    Young Kwok
    J Clin Oncol 23:3308-10. 2005
  55. pmc On statistical reanalysis, the EORTC trial is a positive trial for adjuvant chemoradiation in pancreatic cancer
    Michael C Garofalo
    Ann Surg 244:332-3; author reply 333. 2006
  56. ncbi request reprint Radiosurgery plus whole-brain radiation therapy for brain metastases
    Roy A Patchell
    JAMA 296:2089-90; author reply 2090-1. 2006
  57. ncbi request reprint Low-dose fractionated radiation as a chemopotentiator of neoadjuvant paclitaxel and carboplatin for locally advanced squamous cell carcinoma of the head and neck: results of a new treatment paradigm
    Susanne M Arnold
    Department of Medicine, University of Kentucky Markey Cancer Center, Lexington 40536, USA
    Int J Radiat Oncol Biol Phys 58:1411-7. 2004
    ..On the basis of the demonstrated synergy between chemotherapy and low-dose fractionated RT, a novel neoadjuvant therapy was designed using low-dose fractionated RT as a chemopotentiator for locally advanced SCCHN...
  58. ncbi request reprint Brain injury: current management and investigations
    Andrew E Sloan
    Karmanos Cancer Institute, Wayne State University, Detroit, MI, USA
    Semin Radiat Oncol 13:309-21. 2003
    ..This review presents current management and investigations associated with these modality-related injuries...
  59. ncbi request reprint A phase I trial of continuously infused intratumoral bleomycin for the treatment of recurrent glioblastoma multiforme
    Roy A Patchell
    Department of Neurology, University of Kentucky Medical Center, Lexington 40536, USA
    J Neurooncol 60:37-42. 2002
    ..Neurologic toxicity occurred only at doses above 16 U/wk. We conclude that continuously infused IT bleomycin is well tolerated; the MTD (and recommended dose for a phase II efficacy trial) of IT bleomycin is 16 U/wk...
  60. ncbi request reprint Comments about the prospective randomized trial by Aoyama et al
    Roy A Patchell
    Surg Neurol 66:459-60. 2006