Research Topics
| J G RegensteinerSummaryAffiliation: University of Colorado Health Sciences Center Country: USA Publications
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Detail Information
Publications
Abnormal oxygen uptake kinetic responses in women with type II diabetes mellitusJ G Regensteiner
Section of Vascular Medicine, Department of Medicine, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
J Appl Physiol 85:310-7. 1998..The findings may reflect impaired cardiac responses to exercise, although an additional defect in skeletal muscle oxygen diffusion or mitochondrial oxygen utilization is also possible...- Type 2 diabetes mellitus and cardiovascular exercise performanceJudith G Regensteiner
Department of Medicine, Program for Women's Health Research, Section of Vascular Medicine, Divisions of Internal Medicine and Cardiology, University of Colorado Health Sciences Center, Denver, CO 80262, USA
Rev Endocr Metab Disord 5:269-76. 2004 - Oral L-arginine and vitamins E and C improve endothelial function in women with type 2 diabetesJudith G Regensteiner
Department of Medicine, Division of Internal Medicine, University of Colorado Health Sciences Center, Denver, CO 80262, USA
Vasc Med 8:169-75. 2003..No significant changes in the responses of controls from pre to post vitamin administration were observed. We concluded that administration of two types of oral agents improved measures of endothelial function in people with T2DM... - Rosiglitazone improves exercise capacity in individuals with type 2 diabetesJudith G Regensteiner
Division of Internal Medicine, Center for Women s Health Research, Box B 180, University of Colorado Health Sciences Center, 4200 E 9th Ave, Denver, CO 80262, USA
Diabetes Care 28:2877-83. 2005..We hypothesized that administration of a thiazolidinedione (TZD) agent would improve exercise capacity in type 2 diabetes... - Established and evolving medical therapies for claudication in patients with peripheral arterial diseaseJudith G Regensteiner
Section of Vascular Medicine, Divisions of General Internal Medicine and Cardiology, University of Colorado Health Sciences Center, Box B 180, 4200 E 9th Avenue, Denver, CO 80262, USA
Nat Clin Pract Cardiovasc Med 3:604-10. 2006..The aim of this article is to discuss the current medical treatments being developed for use in patients with claudication resulting from peripheral arterial disease... - Exercise rehabilitation for the patient with intermittent claudication: a highly effective yet underutilized treatmentJudith G Regensteiner
Section of Vascular Medicine, Divisions of Internal Medicine and Cardiology, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
Curr Drug Targets Cardiovasc Haematol Disord 4:233-9. 2004..All therapies which are used to treat claudication should incorporate measures of functional status and quality of life in addition to treadmill walking in order to ascertain the benefit of a given treatment for patients with PAD... - Effect of cilostazol on treadmill walking, community-based walking ability, and health-related quality of life in patients with intermittent claudication due to peripheral arterial disease: meta-analysis of six randomized controlled trialsJudith G Regensteiner
Department of Medicine, Division of Internal Medicine and Cardiology, The University of Colorado Health Sciences Center, Denver 80262, USA
J Am Geriatr Soc 50:1939-46. 2002.... - Treatment of peripheral arterial diseaseJudith G Regensteiner
Divisions of Internal Medicine and Cardiology, University of Colorado Health Sciences Center, Denver, Colorado, USA
Clin Cornerstone 4:26-40. 2002..Although many therapies for claudication have been thoroughly investigated, research continues on new treatments. In contrast, more prospective, randomized trials are needed to evaluate various therapies for treating patients with PAD... 
Cardiac dysfunction during exercise in uncomplicated type 2 diabetesJudith G Regensteiner
Division of General Internal Medicine, Department of Medicine, School of Medicine, University of Colorado Denver, Aurora, CO 80045, USA
Med Sci Sports Exerc 41:977-84. 2009..We hypothesized that exercise would be associated with impaired cardiac function and hemodynamics in recently diagnosed T2DM, even in the absence of clinically evident cardiovascular complications...
The impact of peripheral arterial disease on health-related quality of life in the Peripheral Arterial Disease Awareness, Risk, and Treatment: New Resources for Survival (PARTNERS) ProgramJudith G Regensteiner
Department of Medicine, University of Colorado School of Medicine, Denver, CO 80262, USA
Vasc Med 13:15-24. 2008....- Effects of exercise training on oxygen uptake kinetic responses in women with type 2 diabetesS L Brandenburg
Department of Medicine, University of Colorado Health Sciences Center, Denver 80262, USA
Diabetes Care 22:1640-6. 1999.... - Current medical therapies for patients with peripheral arterial disease: a critical reviewJudith G Regensteiner
Section of Vascular Medicine, Division of Internal Medicine, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
Am J Med 112:49-57. 2002.... - Insulin resistance in adolescents with type 2 diabetes is associated with impaired exercise capacityKristen J Nadeau
Division of Pediatric Endocrinology, The Children s Hospital, University of Colorado Denver School of Medicine, Aurora, Colorado 80045, USA
J Clin Endocrinol Metab 94:3687-95. 2009..Cardiopulmonary fitness, a marker of morbidity and mortality, is abnormal in adults with T2D, yet the mechanisms are incompletely understood... - Risk assessment in the patient with established peripheral arterial diseaseScott Haugen
Divisions of Cardiology and General Internal Medicine, Department of Medicine, University of Colorado School of Medicine, Denver, CO, USA
Vasc Med 12:343-50. 2007..Defining which patients are in the highest category of risk may direct health care providers to emphasize secondary preventive measures, and facilitate patient adherence to recommended medical therapies and smoking cessation... - Exercise training for claudicationKerry J Stewart
Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, USA
N Engl J Med 347:1941-51. 2002 - Minor depression and health status among US adults with diabetes mellitusMarianne McCollum
University of Colorado at Denver and Health Sciences Center, School of Pharmacy, Denver, CO 80262, USA
Am J Manag Care 13:65-72. 2007..To determine whether diabetes mellitus (DM) with minor depression is associated with poorer levels of mental and physical functioning compared with DM without depression... - Effect of niacin ER/lovastatin on claudication symptoms in patients with peripheral artery diseaseWilliam R Hiatt
Section of Vascular Medicine, Division of Geriatrics, University of Colorado Denver School of Medicine, Denver, CO 80203, USA
Vasc Med 15:171-9. 2010..6% on low niacin-statin (p = 0.096). Flushing as the most common event leading to discontinuation and treatment was associated with increases in liver enzymes, fasting blood glucose concentration and a decrease in platelet count... - The effect of inhibition of acyl coenzyme A-cholesterol acyltransferase (ACAT) on exercise performance in patients with peripheral arterial diseaseWilliam R Hiatt
Section of Vascular Medicine, University of Colorado Health Sciences Center, 4200 E 9th Ave, Denver, CO 80262, USA
Vasc Med 9:271-7. 2004.... - Diabetes and advanced glycoxidation end productsAmy G Huebschmann
Division of General Internal Medicine, Department of Medicine, University of Colorado Denver and Health Sciences Center, Mailstop F-729, Aurora, CO 80045, USA
Diabetes Care 29:1420-32. 2006 - Increased levels of apoptosis in gastrocnemius skeletal muscle in patients with peripheral arterial diseaseRobert G Mitchell
Division of Cardiology, Department of Medicine, Durham VA and Duke University Medical Center, Durham, NC 27710, USA
Vasc Med 12:285-90. 2007..53% +/- 0.96; p < 0.001). In conclusion, PAD is associated with increased levels of apoptosis in the peripheral skeletal muscle. Further study is required to ascertain whether apoptosis plays a role in decreased functional capacity... - Impaired fibrinolysis in premenopausal women and age-matched men with Type 2 diabetes mellitus: a pilot studySuzanne L Brandenburg
Department of Medicine, Division of General Internal Medicine, University of Colorado Health Sciences Center, Denver 80262, USA
J Investig Med 50:110-5. 2002..This pilot study compared fibrinolytic measures in premenopausal women and men with DM with those of healthy age-matched control women and men to help determine whether fibrinolysis is abnormal in women with DM... - Peripheral arterial disease rehabilitation: a reviewRita A Falcone
Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA
J Cardiopulm Rehabil 23:170-5. 2003 - Functional outcome in a contemporary series of major lower extremity amputationsMark R Nehler
University of Colorado Health Sciences Center, Department of Surgery, Vascular Surgery Section, Denver, CO 80262, USA
J Vasc Surg 38:7-14. 2003..We undertook this study to document the functional natural history of patients undergoing major amputation in an academic vascular surgery and rehabilitation medicine practice... - Functional outcomes and quality of life in peripheral arterial disease: current statusMark R Nehler
Section of Vascular Surgery, Department of Surgery, University of Colorado Health Sciences Center, Denver, CO 80262 0312, USA
Vasc Med 8:115-26. 2003.... - Cardiovascular risk in women with type 2 diabetesSuzanne L Brandenburg
Division of General Internal Medicine, Department of Medicine, University of Colorado Health Sciences Center, Box B 180, 4200 East 9th Avenue, Denver, CO 80262, USA
Med Clin North Am 87:955-69. 2003.... - Skeletal muscle deoxygenation after the onset of moderate exercise suggests slowed microvascular blood flow kinetics in type 2 diabetesTimothy A Bauer
Division of Cardiology, University of Colorado at Denver and Health Sciences Center, Denver, Colorado, USA
Diabetes Care 30:2880-5. 2007.... - Lack of relationship between gait parameters and physical function in peripheral arterial diseaseSusan A Scherer
Regis University, University of Colorado Denver, Denver, CO 80221, USA
J Vasc Surg 44:782-8. 2006..The aims were to evaluate usual and maximal walking speed and gait parameters (step length, cadence and toe out angle) in subjects with PAD-IC and control subjects with similar baseline activity levels... - Physical activity in prevention and management of obesity and type-2 diabetesJames O Hill
Center for Human Nutrition, University of Colorado School of Medicine, Denver, CO, USA
Nestle Nutr Workshop Ser Clin Perform Programme 11:183-91; discussion 191-6. 2006..However, we still face an enormous challenge in getting people to achieve sustainable increases in physical activity. A promising strategy is to get people walking more, starting small and increasing gradually over time... - Novel actions of thiazolidinediones on vascular function and exercise capacityJane E B Reusch
Denver Veterans Affairs Medical Center, Denver, Colorado 80220, USA
Am J Med 115:69S-74S. 2003..Preliminary data suggest that TZDs improve measures of cardiac function and exercise capacity, and investigators are assessing the impact of treatment with rosiglitazone on exercise capacity in an ongoing clinical trial... - Propionyl-L-carnitine improves exercise performance and functional status in patients with claudicationW R Hiatt
Department of Medicine, Section of Vascular Medicine, Divisions of Geriatrics and Cardiology, University of Colorado Health Sciences Center, Denver 80203, USA
Am J Med 110:616-22. 2001..CONCLUSIONS: Propionyl-L-carnitine safely improved treadmill exercise performance and enhanced functional status in patients with claudication... - Design of the Del-1 for therapeutic angiogenesis trial (DELTA-1), a phase II multicenter, double-blind, placebo-controlled trial of VLTS-589 in subjects with intermittent claudication secondary to peripheral arterial diseaseSanjay Rajagopalan
Section of Vascular Medicine, Zena and Michael A Wiener Cardiovascular Institute, Mount Sinai School of Medicine, Box 1030, One Gustave Levy Place, New York, NY 10029, USA
Hum Gene Ther 15:619-24. 2004.... - Women with type 2 diabetes perceive harder effort during exercise than nondiabetic womenAmy G Huebschmann
Division of General Internal Medicine, University of Colorado Denver School of Medicine, Aurora, CO 80045, USA
Appl Physiol Nutr Metab 34:851-7. 2009..Harder perceived effort during exercise may be a barrier to physical activity for those with T2D... - Insulin resistance in adolescents with type 1 diabetes and its relationship to cardiovascular functionKristen J Nadeau
AssistantUniversity of Colorado Health Sciences Center, The Children s Hospital, Department of Pediatric Endocrinology B265, 13123 East 16th Avenue, Aurora, Colorado 80045, USA
J Clin Endocrinol Metab 95:513-21. 2010..The phenotype of IR in T1D youth was unique, suggesting a pathophysiology that is different from T2D, yet may adversely affect long-term cardiovascular outcomes... - Attendance and graduation patterns in a group-model health maintenance organization alternative cardiac rehabilitation programAndria M Ratchford
University of Colorado Health Sciences Center, Denver, USA
J Cardiopulm Rehabil 24:150-6. 2004..This study evaluated the participation rates for the program and the predictors of attendance and graduation... - Extension of type 2 diabetes genome-wide association scan results in the diabetes prevention programAllan F Moore
Center for Human Genetic Research, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA
Diabetes 57:2503-10. 2008.... - The Claudication: Exercise Vs. Endoluminal Revascularization (CLEVER) study: rationale and methodsTimothy P Murphy
Rhode Island Hospital Vascular Disease Research Center and Brown Medical School Department of Diagnostic Imaging, Providence, RI 02903, USA
J Vasc Surg 47:1356-63. 2008.... - Physical activity in individuals at risk for diabetes: Diabetes Prevention ProgramAndrea M Kriska
Diabetes Prevention Program Research Group, George Washington University, Rockville, MD 20852, USA
Med Sci Sports Exerc 38:826-32. 2006..This provided the opportunity to examine the relationship between the three activity measures and to compare activity levels of the DPP sample with that of a national sample with IGT... - Dietary intake in the diabetes prevention program cohort: baseline and 1-year post randomizationElizabeth J Mayer-Davis
The Diabetes Prevention Program Coordinating Center, George Washington University Biostatistics Center, Rockville, MD 20852, USA
Ann Epidemiol 14:763-72. 2004..To describe usual dietary intake assessment at baseline and 1-year post-randomization in the ethnically diverse Diabetes Prevention Program cohort... - A patient-derived perspective of health-related quality of life with peripheral arterial diseaseDiane Treat-Jacobson
University of Minnesota, USA
J Nurs Scholarsh 34:55-60. 2002..To evaluate the effects of peripheral artery disease (PAD) on health-related quality of life (HRQoL) from the patient's perspective to establish a foundation for systematic PAD-specific HRQoL assessment in this population... - Achieving weight and activity goals among diabetes prevention program lifestyle participantsRena R Wing
Prevention Program Coordinating Center, The Biostatistics Center, George Washington University, 6110 Executive Boulevard, Suite 750, Rockville, MD 20852, USA
Obes Res 12:1426-34. 2004..This paper examines demographic, psychosocial, and behavioral factors related to achieving weight loss and physical activity goals in the DPP lifestyle participants... - Evaluating effects of method of administration on Walking Impairment QuestionnaireKarin S Coyne
MEDTAP International, 7101 Wisconsin Avenue, Suite 600, Bethesda, MD 20814, USA
J Vasc Surg 38:296-304. 2003..Currently this questionnaire is validated for interviewer administration only. Since this can be burdensome in a large clinical trial, we examined the effects of alternative methods of administration on patient responses on the WIQ...