William T Regenold

Summary

Affiliation: University of Maryland
Country: USA

Publications

  1. doi request reprint Older adult psychiatric inpatients with non-cognitive disorders should be screened for vitamin B12 deficiency
    C Lachner
    William T Regenold, M D C M, Associate Professor, Director, Division of Geriatric Psychiatry, University of Maryland Medical Center, Department of Psychiatry S12A09, 22 South Greene St Baltimore, MD 21201, P 410 328 6511, Fax 410 328 5584
    J Nutr Health Aging 18:209-12. 2014
  2. doi request reprint Mitochondrial detachment of hexokinase 1 in mood and psychotic disorders: implications for brain energy metabolism and neurotrophic signaling
    W T Regenold
    Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    J Psychiatr Res 46:95-104. 2012
  3. pmc Cerebrospinal fluid evidence of increased extra-mitochondrial glucose metabolism implicates mitochondrial dysfunction in multiple sclerosis disease progression
    William T Regenold
    University of Maryland School of Medicine, Department of Psychiatry, Division of Geriatric Psychiatry, Baltimore, MD 21201, USA
    J Neurol Sci 275:106-12. 2008
  4. pmc Elevated cerebrospinal fluid lactate concentrations in patients with bipolar disorder and schizophrenia: implications for the mitochondrial dysfunction hypothesis
    William T Regenold
    Division of Geriatric Psychiatry, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
    Biol Psychiatry 65:489-94. 2009
  5. ncbi request reprint Myelin staining of deep white matter in the dorsolateral prefrontal cortex in schizophrenia, bipolar disorder, and unipolar major depression
    William T Regenold
    University of Maryland School of Medicine, Department of Psychiatry, Division of Geriatric Psychiatry and the Baltimore Veterans Affairs Medical Center, Baltimore, MD 21201, USA
    Psychiatry Res 151:179-88. 2007
  6. ncbi request reprint Increased prevalence of type 2 diabetes mellitus among psychiatric inpatients with bipolar I affective and schizoaffective disorders independent of psychotropic drug use
    William T Regenold
    University of Maryland Baltimore VAMC Mood Disorders Program, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    J Affect Disord 70:19-26. 2002
  7. pmc Relationship of cerebrospinal fluid glucose metabolites to MRI deep white matter hyperintensities and treatment resistance in bipolar disorder patients
    William T Regenold
    Department of Psychiatry, Division of Geriatric Psychiatry, University of Maryland School of Medicine, Baltimore, MD
    Bipolar Disord 10:753-64. 2008
  8. ncbi request reprint Relationship of white matter hyperintensities to cerebrospinal fluid glucose polyol pathway metabolites-a pilot study in treatment-resistant affective disorder patients
    William T Regenold
    Division of Geriatric Psychiatry, Department of Psychiatry, University of Maryland School of Medicine, and Research Service, VA Maryland Healthcare System, Baltimore, MD 21201, USA
    J Affect Disord 85:341-50. 2005
  9. ncbi request reprint Diffusion-weighted magnetic resonance imaging of white matter in bipolar disorder: a pilot study
    William T Regenold
    Geriatric Division, Department of Psychiatry, University of Maryland School of Medicine, VA Maryland Healthcare System, Baltimore, MD 21201, USA
    Bipolar Disord 8:188-95. 2006
  10. ncbi request reprint Increased plasma concentration of brain-derived neurotrophic factor with electroconvulsive therapy: a pilot study in patients with major depression
    Christopher M Marano
    Department of Psychiatry, University of Maryland School of Medicine, Baltimore, USA
    J Clin Psychiatry 68:512-7. 2007

Research Grants

  1. Mood Disorders & Diabetes: Common Disease Mechanisms
    WILLIAM REGENOLD; Fiscal Year: 2005

Collaborators

Detail Information

Publications16

  1. doi request reprint Older adult psychiatric inpatients with non-cognitive disorders should be screened for vitamin B12 deficiency
    C Lachner
    William T Regenold, M D C M, Associate Professor, Director, Division of Geriatric Psychiatry, University of Maryland Medical Center, Department of Psychiatry S12A09, 22 South Greene St Baltimore, MD 21201, P 410 328 6511, Fax 410 328 5584
    J Nutr Health Aging 18:209-12. 2014
    ....
  2. doi request reprint Mitochondrial detachment of hexokinase 1 in mood and psychotic disorders: implications for brain energy metabolism and neurotrophic signaling
    W T Regenold
    Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    J Psychiatr Res 46:95-104. 2012
    ..We propose that HK1 mitochondrial detachment could be linked to these disorders through impaired energy metabolism, increased vulnerability to oxidative stress, and impaired brain growth and development...
  3. pmc Cerebrospinal fluid evidence of increased extra-mitochondrial glucose metabolism implicates mitochondrial dysfunction in multiple sclerosis disease progression
    William T Regenold
    University of Maryland School of Medicine, Department of Psychiatry, Division of Geriatric Psychiatry, Baltimore, MD 21201, USA
    J Neurol Sci 275:106-12. 2008
    ..CSF metabolic profiling may be useful in clarifying the role of mitochondrial pathology in progression and in targeting and monitoring therapies for disease progression that aim to preserve or boost mitochondrial glucose metabolism...
  4. pmc Elevated cerebrospinal fluid lactate concentrations in patients with bipolar disorder and schizophrenia: implications for the mitochondrial dysfunction hypothesis
    William T Regenold
    Division of Geriatric Psychiatry, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
    Biol Psychiatry 65:489-94. 2009
    ..We tested the hypothesis that patients with bipolar disorder and schizophrenia would, on average, have elevated CSF lactate concentrations compared with healthy control subjects...
  5. ncbi request reprint Myelin staining of deep white matter in the dorsolateral prefrontal cortex in schizophrenia, bipolar disorder, and unipolar major depression
    William T Regenold
    University of Maryland School of Medicine, Department of Psychiatry, Division of Geriatric Psychiatry and the Baltimore Veterans Affairs Medical Center, Baltimore, MD 21201, USA
    Psychiatry Res 151:179-88. 2007
    ..Our findings are consistent with postmortem and neuroimaging studies of affective disorders that indicate an increased prevalence of deep white matter lesions in unipolar and bipolar affective disorders...
  6. ncbi request reprint Increased prevalence of type 2 diabetes mellitus among psychiatric inpatients with bipolar I affective and schizoaffective disorders independent of psychotropic drug use
    William T Regenold
    University of Maryland Baltimore VAMC Mood Disorders Program, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    J Affect Disord 70:19-26. 2002
    ..This study aimed to clarify this relationship...
  7. pmc Relationship of cerebrospinal fluid glucose metabolites to MRI deep white matter hyperintensities and treatment resistance in bipolar disorder patients
    William T Regenold
    Department of Psychiatry, Division of Geriatric Psychiatry, University of Maryland School of Medicine, Baltimore, MD
    Bipolar Disord 10:753-64. 2008
    ..This study investigated whether brain glucose metabolism by the polyol pathway--a pathway linked to nervous tissue disease in diabetes--is related to deep WMH volume and treatment resistance in BD patients...
  8. ncbi request reprint Relationship of white matter hyperintensities to cerebrospinal fluid glucose polyol pathway metabolites-a pilot study in treatment-resistant affective disorder patients
    William T Regenold
    Division of Geriatric Psychiatry, Department of Psychiatry, University of Maryland School of Medicine, and Research Service, VA Maryland Healthcare System, Baltimore, MD 21201, USA
    J Affect Disord 85:341-50. 2005
    ....
  9. ncbi request reprint Diffusion-weighted magnetic resonance imaging of white matter in bipolar disorder: a pilot study
    William T Regenold
    Geriatric Division, Department of Psychiatry, University of Maryland School of Medicine, VA Maryland Healthcare System, Baltimore, MD 21201, USA
    Bipolar Disord 8:188-95. 2006
    ....
  10. ncbi request reprint Increased plasma concentration of brain-derived neurotrophic factor with electroconvulsive therapy: a pilot study in patients with major depression
    Christopher M Marano
    Department of Psychiatry, University of Maryland School of Medicine, Baltimore, USA
    J Clin Psychiatry 68:512-7. 2007
    ..To investigate a neurotrophic effect in humans, we examined whether plasma concentration of brain-derived neurotrophic factor (BDNF) increases in patients receiving ECT for major depression...
  11. doi request reprint The neuropsychiatry of vitamin B12 deficiency in elderly patients
    Christian Lachner
    Department of Psychiatry, Division of Geriatric Psychiatry, University of Maryland School of Medicine, MD, USA
    J Neuropsychiatry Clin Neurosci 24:5-15. 2012
    ..This clinical review focuses on important aspects of the recognition and treatment of vitamin B12 deficiency and neuropsychiatric manifestations of this preventable illness in elderly patients...
  12. pmc Pollen-specific immunoglobulin E positivity is associated with worsening of depression scores in bipolar disorder patients during high pollen season
    Partam Manalai
    Mood and Anxiety Program, Department of Psychiatry, University of Maryland at Baltimore, Baltimore, MD, USA
    Bipolar Disord 14:90-8. 2012
    ..In the current study, we examined a hypothesized relationship between allergen-specific immunoglobulin E (IgE) status and changes in allergy symptoms with worsening in depression scores...
  13. ncbi request reprint The association between decreasing length of stay and readmission rate on a psychogeriatric unit
    Oscar Heeren
    Department of Psychiatry, University of Maryland, Baltimore, MD 21201, USA
    Psychiatr Serv 53:76-9. 2002
    ..This study investigated whether there was an association between decreasing length of stay and readmission rate on a psychogeriatric unit...
  14. ncbi request reprint Lithium and increased cortical gray matter-more tissue or more water?
    William T Regenold
    Biol Psychiatry 63:e17; author reply e19. 2008
  15. ncbi request reprint Inositol deficiency diet and lithium effects
    Alona Shaldubina
    Stanley Research Center, Ministry of Health, Beer Sheba Mental Health Center, Beer Sheva, Israel
    Bipolar Disord 8:152-9. 2006
    ..However, inositol is also present in the diet. Restriction of dietary inositol could theoretically enhance the effects of Li...
  16. ncbi request reprint Lithium and increased hippocampal volume-more tissue or more water?
    William T Regenold
    Neuropsychopharmacology 33:1773-4; author reply 1775. 2008

Research Grants1

  1. Mood Disorders & Diabetes: Common Disease Mechanisms
    WILLIAM REGENOLD; Fiscal Year: 2005
    ..S. Such treatments could have the potential not only to provide symptom relief but also to repair and prevent the brain disease contributing to treatment resistance. ..