Majed A Refaai
Affiliation: University of Rochester
- The transfusion dilemma - weighing the known and newly proposed risks of blood transfusions against the uncertain benefitsMajed A Refaai
Department of Pathology and Laboratory Medicine, University of Rochester Medical Center, Box 608, Rochester, NY 14642, USA
Best Pract Res Clin Anaesthesiol 27:17-35. 2013..One long-standing primary concern has been bacterial and viral contamination but recently other risks have been identified, mostly related to recipient immunomodulation and storage lesion-related changes...
- Alterations of platelet function and clot formation kinetics after in vitro exposure to anti-A and -BMajed A Refaai
Department of Pathology and Laboratory Medicine, The James P Wilmot Cancer Center, University of Rochester, Rochester, New York 14642, USA
Transfusion 53:382-93. 2013..We present here in vitro modeling data on the functional effects of exposure of PLTs to ABO antibodies...
- Platelet transfusions: impact on hemostasis, thrombosis, inflammation and clinical outcomesMajed A Refaai
Department of Pathology and Laboratory Medicine, University of Rochester Medical Center, Rochester, NY 14642, USA
Thromb Res 127:287-91. 2011..In this review, we will briefly highlight the importance of platelet transfusion, its role in inflammatory and thrombotic transfusion reactions, and visit the most recent findings on sCD40L...
- An association of ABO non-identical platelet and cryoprecipitate transfusions with altered red cell transfusion needs in surgical patientsMajed A Refaai
Department of Pathology and Laboratory Medicine, University of Rochester, Rochester, NY, USA
Vox Sang 101:55-60. 2011..Transfusion of ABO non-identical plasma, platelets and cryoprecipitate is routine practice even though adverse effects can occur...
- Providing ABO-identical platelets and cryoprecipitate to (almost) all patients: approach, logistics, and associated decreases in transfusion reaction and red blood cell alloimmunization incidenceKelly F Henrichs
Department of Pathology and Laboratory Medicine, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA
Transfusion 52:635-40. 2012..In April 2005, we implemented a policy of transfusing only ABO-identical components whenever feasible, regardless of outdating or logistic considerations...
- An association between decreased cardiopulmonary complications (transfusion-related acute lung injury and transfusion-associated circulatory overload) and implementation of universal leukoreduction of blood transfusionsNeil Blumberg
Transfusion Medicine Unit, and the Department of Pathology and Laboratory Medicine, University of Rochester Medical Center, Rochester, New York 14642, USA
Transfusion 50:2738-44. 2010..Cardiopulmonary adverse events after transfusion include transfusion-related acute lung injury (TRALI) and transfusion-associated circulatory overload (TACO), which are potentially lethal and incompletely understood...
- Platelet aggregation responses vary over a period of time in healthy controlsMajed A Refaai
Department of Pathology and Laboratory Medicine, University of Rochester Medical Center, Rochester, New York, USA
Platelets 21:460-3. 2010..Therefore, a repeat study at a later date to demonstrate a reproducible abnormality would be prudent before labeling a patient's platelets abnormal...
- Blood transfusions, thrombosis, and mortality in hospitalized patients with cancerAlok A Khorana
James P Wilmot Cancer Center, Department of Medicine, University of Rochester, Rochester, New York, USA
Arch Intern Med 168:2377-81. 2008..Anemia is frequent in patients with cancer, but there are concerns regarding treatment with erythropoiesis-stimulating agents. Blood transfusions are commonly used as an alternative, but with little data regarding outcomes...