Majed A Refaai

Summary

Affiliation: University of Rochester
Country: USA

Publications

  1. doi request reprint The transfusion dilemma--weighing the known and newly proposed risks of blood transfusions against the uncertain benefits
    Majed A Refaai
    Department of Pathology and Laboratory Medicine, University of Rochester Medical Center, Box 608, Rochester, NY 14642, USA
    Best Pract Res Clin Anaesthesiol 27:17-35. 2013
  2. pmc Alterations of platelet function and clot formation kinetics after in vitro exposure to anti-A and -B
    Majed A Refaai
    Department of Pathology and Laboratory Medicine, The James P Wilmot Cancer Center, University of Rochester, Rochester, New York 14642, USA
    Transfusion 53:382-93. 2013
  3. pmc Platelet transfusions: impact on hemostasis, thrombosis, inflammation and clinical outcomes
    Majed A Refaai
    Department of Pathology and Laboratory Medicine, University of Rochester Medical Center, Rochester, NY 14642, USA
    Thromb Res 127:287-91. 2011
  4. pmc An association of ABO non-identical platelet and cryoprecipitate transfusions with altered red cell transfusion needs in surgical patients
    Majed A Refaai
    Department of Pathology and Laboratory Medicine, University of Rochester, Rochester, NY, USA
    Vox Sang 101:55-60. 2011
  5. pmc Providing ABO-identical platelets and cryoprecipitate to (almost) all patients: approach, logistics, and associated decreases in transfusion reaction and red blood cell alloimmunization incidence
    Kelly F Henrichs
    Department of Pathology and Laboratory Medicine, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA
    Transfusion 52:635-40. 2012
  6. pmc Isoprostane and isofuran lipid mediators accumulate in stored red blood cells and influence platelet function in vitro
    Sherry L Spinelli
    Department of Pathology and Laboratory Medicine, University of Rochester School of Medicine and Dentistry, Rochester, New York
    Transfusion 54:1569-79. 2014
  7. pmc An association between decreased cardiopulmonary complications (transfusion-related acute lung injury and transfusion-associated circulatory overload) and implementation of universal leukoreduction of blood transfusions
    Neil Blumberg
    Transfusion Medicine Unit, and the Department of Pathology and Laboratory Medicine, University of Rochester Medical Center, Rochester, New York 14642, USA
    Transfusion 50:2738-44. 2010
  8. ncbi request reprint Transfusion immunomodulation from a clinical perspective: an update
    Majed A Refaai
    Department of Pathology and Laboratory Medicine, University of Rochester Medical Center, 601 Elmwood Avenue, Box 608, Rochester, NY 14642, USA
    Expert Rev Hematol 6:653-63. 2013
  9. pmc Blood transfusions, thrombosis, and mortality in hospitalized patients with cancer
    Alok A Khorana
    James P Wilmot Cancer Center, Department of Medicine, University of Rochester, Rochester, New York, USA
    Arch Intern Med 168:2377-81. 2008
  10. doi request reprint Platelet aggregation responses vary over a period of time in healthy controls
    Majed A Refaai
    Department of Pathology and Laboratory Medicine, University of Rochester Medical Center, Rochester, New York, USA
    Platelets 21:460-3. 2010

Collaborators

Detail Information

Publications10

  1. doi request reprint The transfusion dilemma--weighing the known and newly proposed risks of blood transfusions against the uncertain benefits
    Majed A Refaai
    Department of Pathology and Laboratory Medicine, University of Rochester Medical Center, Box 608, Rochester, NY 14642, USA
    Best Pract Res Clin Anaesthesiol 27:17-35. 2013
    ..One long-standing primary concern has been bacterial and viral contamination but recently other risks have been identified, mostly related to recipient immunomodulation and storage lesion-related changes...
  2. pmc Alterations of platelet function and clot formation kinetics after in vitro exposure to anti-A and -B
    Majed A Refaai
    Department of Pathology and Laboratory Medicine, The James P Wilmot Cancer Center, University of Rochester, Rochester, New York 14642, USA
    Transfusion 53:382-93. 2013
    ..We present here in vitro modeling data on the functional effects of exposure of PLTs to ABO antibodies...
  3. pmc Platelet transfusions: impact on hemostasis, thrombosis, inflammation and clinical outcomes
    Majed A Refaai
    Department of Pathology and Laboratory Medicine, University of Rochester Medical Center, Rochester, NY 14642, USA
    Thromb Res 127:287-91. 2011
    ..In this review, we will briefly highlight the importance of platelet transfusion, its role in inflammatory and thrombotic transfusion reactions, and visit the most recent findings on sCD40L...
  4. pmc An association of ABO non-identical platelet and cryoprecipitate transfusions with altered red cell transfusion needs in surgical patients
    Majed A Refaai
    Department of Pathology and Laboratory Medicine, University of Rochester, Rochester, NY, USA
    Vox Sang 101:55-60. 2011
    ..Transfusion of ABO non-identical plasma, platelets and cryoprecipitate is routine practice even though adverse effects can occur...
  5. pmc Providing ABO-identical platelets and cryoprecipitate to (almost) all patients: approach, logistics, and associated decreases in transfusion reaction and red blood cell alloimmunization incidence
    Kelly F Henrichs
    Department of Pathology and Laboratory Medicine, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA
    Transfusion 52:635-40. 2012
    ..In April 2005, we implemented a policy of transfusing only ABO-identical components whenever feasible, regardless of outdating or logistic considerations...
  6. pmc Isoprostane and isofuran lipid mediators accumulate in stored red blood cells and influence platelet function in vitro
    Sherry L Spinelli
    Department of Pathology and Laboratory Medicine, University of Rochester School of Medicine and Dentistry, Rochester, New York
    Transfusion 54:1569-79. 2014
    ..This study investigated RBC-derived F2 -IsoPs and IsoFs during storage and their influence on human platelets (PLTs)...
  7. pmc An association between decreased cardiopulmonary complications (transfusion-related acute lung injury and transfusion-associated circulatory overload) and implementation of universal leukoreduction of blood transfusions
    Neil Blumberg
    Transfusion Medicine Unit, and the Department of Pathology and Laboratory Medicine, University of Rochester Medical Center, Rochester, New York 14642, USA
    Transfusion 50:2738-44. 2010
    ..Cardiopulmonary adverse events after transfusion include transfusion-related acute lung injury (TRALI) and transfusion-associated circulatory overload (TACO), which are potentially lethal and incompletely understood...
  8. ncbi request reprint Transfusion immunomodulation from a clinical perspective: an update
    Majed A Refaai
    Department of Pathology and Laboratory Medicine, University of Rochester Medical Center, 601 Elmwood Avenue, Box 608, Rochester, NY 14642, USA
    Expert Rev Hematol 6:653-63. 2013
    ..Most important is adopting more conservative transfusion practices. Leukoreduction (proven) and plasma depletion (proposed) are other methods to significantly reduce transfusion immunomodulation and its clinical sequela...
  9. pmc Blood transfusions, thrombosis, and mortality in hospitalized patients with cancer
    Alok A Khorana
    James P Wilmot Cancer Center, Department of Medicine, University of Rochester, Rochester, New York, USA
    Arch Intern Med 168:2377-81. 2008
    ..Anemia is frequent in patients with cancer, but there are concerns regarding treatment with erythropoiesis-stimulating agents. Blood transfusions are commonly used as an alternative, but with little data regarding outcomes...
  10. doi request reprint Platelet aggregation responses vary over a period of time in healthy controls
    Majed A Refaai
    Department of Pathology and Laboratory Medicine, University of Rochester Medical Center, Rochester, New York, USA
    Platelets 21:460-3. 2010
    ..Therefore, a repeat study at a later date to demonstrate a reproducible abnormality would be prudent before labeling a patient's platelets abnormal...