Gregory A Reed
Affiliation: University of Kansas Medical Center
- Design, recruitment, and retention of African-American smokers in a pharmacokinetic studyBabalola Faseru
Department of Preventive Medicine and Public Health, University of Kansas Medical Center, Kansas City, KS, USA
BMC Med Res Methodol 10:6. 2010..The purpose of this article is to describe the study design and discuss strategies used to recruit and retain African-American smokers in a pharmacokinetic study...
- A phase I study of indole-3-carbinol in women: tolerability and effectsGregory A Reed
Department of Medicine, University of Kansas Medical Center, 3901 Rainbow Boulevard, Kansas City, KS 66160, USA
Cancer Epidemiol Biomarkers Prev 14:1953-60. 2005..If the ratio of hydroxylated estrone metabolites is a biomarker for chemoprevention, as suggested, then 400 mg I3C daily will elicit a maximal protective effect...
- Single-dose and multiple-dose administration of indole-3-carbinol to women: pharmacokinetics based on 3,3'-diindolylmethaneGregory A Reed
Department of Internal Medicien, University of Kansas Medical Center, MS 1018, 3901 Rainbow Boulevard, Kansas City, KS 66160, USA
Cancer Epidemiol Biomarkers Prev 15:2477-81. 2006..Possible reasons for this disparity between apparent t1/2 of DIM and the high predose values are discussed...
- Single-dose pharmacokinetics and tolerability of absorption-enhanced 3,3'-diindolylmethane in healthy subjectsGregory A Reed
Departments of Pharmacology, Toxicology, and Therapeutics, University of Kansas Medical Center, 3901 Rainbow Boulevard, Kansas City, KS 66160, USA
Cancer Epidemiol Biomarkers Prev 17:2619-24. 2008..We conclude that BR-DIM is well tolerated at single doses of up to 200 mg, and that increasing the dose to 300 mg did not result in an increase in C(max)...
- Dopamine receptor alterations in female rats with diet-induced decreased brain docosahexaenoic acid (DHA): interactions with reproductive statusPaul F Davis
Department of Pharmacology, Toxicology, and Therapeutics, University of Kansas Medical Center Kansas City, Kansas, USA
Nutr Neurosci 13:161-9. 2010..These receptor alterations are similar to those found in several rodent models of depression, and are consistent with the proposed hypodopaminergic basis for anhedonia and motivational deficits in depression...
- Decreased brain docosahexaenoic acid content produces neurobiological effects associated with depression: Interactions with reproductive status in female ratsBeth Levant
Department of Pharmacology, Toxicology, and Therapeutics, University of Kansas Medical Center, Kansas City, KS 66160, USA
Psychoneuroendocrinology 33:1279-92. 2008..Furthermore, the data are consistent with findings in depressed humans, and thus support a role for DHA as a factor in the etiologies of depressive illnesses, particularly postpartum depression...
- Probe Drugs for Botanical-Drug InteractionsGregory Reed; Fiscal Year: 2007..In addition, not all people are affected to the same extent. This project wjll test a procedure to better understand and predict the effects of Saint John's wort on prescription drugs in people. ..