Research Topics
Species | M T RedingSummaryAffiliation: University of Minnesota Country: USA Publications
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Publications
Human CD4+ T-cell epitope repertoire on the C2 domain of coagulation factor VIIIM T Reding
Department of Biochemistry, University of Minnesota, Minneapolis, MN 55455, USA
J Thromb Haemost 1:1777-84. 2003..Although similar, there appear to be important differences in the CD4+ epitope repertoires of congenital and acquired hemophilia patients...
Epitope repertoire of human CD4(+) T cells on the A3 domain of coagulation factor VIIIM T Reding
Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, 420 Delaware Street SE, MMC 480, Minneapolis, MN 55455, USA
J Thromb Haemost 2:1385-94. 2004..In contrast, CD4(+) T cells sensitized to sequences 1691-1710 and 1941-60, which are recognized by healthy subjects and hemophilia A patients without inhibitors, might curb inhibitor synthesis...
Immunological aspects of inhibitor developmentM T Reding
Division of Hematology, Oncology and Transplantation, Hemophilia and Thrombosis Center, University of Minnesota, Minneapolis, MN, USA
Haemophilia 12:30-5; discussion 35-6. 2006....
CD4+ T cells specific for factor VIII as a target for specific suppression of inhibitor productionM T Reding
Department of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota, Minneapolis-St. Paul, USA
Adv Exp Med Biol 489:119-34. 2001....
Successful liver transplantation in a patient with severe haemophilia A and a high-titre factor VIII inhibitorA A Ashrani
Department of Medicine, University of Minnesota Medical School, Minneapolis, MN, USA
Haemophilia 10:735-7. 2004..This case illustrates the technical feasibility of OLT in some patients with high-titre inhibitors to FVIII, and suggests that immune tolerance may be induced by endogenously produced FVIII from the transplanted organ...
Thrombotic stroke associated with the use of porcine factor VIII in a patient with acquired haemophiliaA A Ashrani
Division of Hematology, Oncology and Transplantation, Department of Medicine, University of Minnesota Medical School, Minneapolis 55455, USA
Haemophilia 8:56-8. 2002..We speculate that platelet activation induced by pFVIII may have contributed to thrombosis and suggest that pFVIII be used with caution in elderly patients with pre-existing cardiovascular risk factors...
Inhibitor treatment in haemophilias A and B: summary statement for the 2006 international consensus conferenceE Berntorp
Department of Coagulation Disorders, Malmo University Hospital, Malmo, Sweden
Haemophilia 12:1-7. 2006..Finally, conference participants urged their colleagues to participate in the currently ongoing international trials of ITI...
