M T Reding

Summary

Affiliation: University of Minnesota
Country: USA

Publications

  1. pmc Barriers to effective diagnosis and management of a bleeding patient with undiagnosed bleeding disorder across multiple specialties: results of a quantitative case-based survey
    Mark T Reding
    Center for Bleeding and Clotting Disorders, University of Minnesota Medical Center, Minneapolis, MN
    J Multidiscip Healthc 5:277-87. 2012
  2. ncbi request reprint Human CD4+ T-cell epitope repertoire on the C2 domain of coagulation factor VIII
    M T Reding
    Department of Biochemistry, University of Minnesota, Minneapolis, MN 55455, USA
    J Thromb Haemost 1:1777-84. 2003
  3. ncbi request reprint Epitope repertoire of human CD4(+) T cells on the A3 domain of coagulation factor VIII
    M T Reding
    Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, 420 Delaware Street SE, MMC 480, Minneapolis, MN 55455, USA
    J Thromb Haemost 2:1385-94. 2004
  4. ncbi request reprint Immunological aspects of inhibitor development
    M T Reding
    Division of Hematology, Oncology and Transplantation, Hemophilia and Thrombosis Center, University of Minnesota, Minneapolis, MN, USA
    Haemophilia 12:30-5; discussion 35-6. 2006
  5. ncbi request reprint CD4+ T cells specific for factor VIII as a target for specific suppression of inhibitor production
    M T Reding
    Department of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota, Minneapolis-St. Paul, USA
    Adv Exp Med Biol 489:119-34. 2001
  6. ncbi request reprint Successful liver transplantation in a patient with severe haemophilia A and a high-titre factor VIII inhibitor
    A A Ashrani
    Department of Medicine, University of Minnesota Medical School, Minneapolis, MN, USA
    Haemophilia 10:735-7. 2004
  7. doi request reprint Randomized, controlled, parallel-group trial of routine prophylaxis vs. on-demand treatment with sucrose-formulated recombinant factor VIII in adults with severe hemophilia A (SPINART)
    M J Manco-Johnson
    Department of Pediatrics, Hemophilia and Thrombosis Center, University of Colorado, Aurora, CO 80045, USA
    J Thromb Haemost 11:1119-27. 2013
  8. ncbi request reprint Thrombotic stroke associated with the use of porcine factor VIII in a patient with acquired haemophilia
    A A Ashrani
    Division of Hematology, Oncology and Transplantation, Department of Medicine, University of Minnesota Medical School, Minneapolis 55455, USA
    Haemophilia 8:56-8. 2002
  9. ncbi request reprint Inhibitor treatment in haemophilias A and B: summary statement for the 2006 international consensus conference
    E Berntorp
    Department of Coagulation Disorders, Malmo University Hospital, Malmo, Sweden
    Haemophilia 12:1-7. 2006

Detail Information

Publications9

  1. pmc Barriers to effective diagnosis and management of a bleeding patient with undiagnosed bleeding disorder across multiple specialties: results of a quantitative case-based survey
    Mark T Reding
    Center for Bleeding and Clotting Disorders, University of Minnesota Medical Center, Minneapolis, MN
    J Multidiscip Healthc 5:277-87. 2012
    ..Acquired hemophilia is a potentially life-threatening cause of unexplained acute bleeding manifested by an abnormal activated partial thromboplastin time (aPTT) that does not correct with 1:1 mixing with normal plasma...
  2. ncbi request reprint Human CD4+ T-cell epitope repertoire on the C2 domain of coagulation factor VIII
    M T Reding
    Department of Biochemistry, University of Minnesota, Minneapolis, MN 55455, USA
    J Thromb Haemost 1:1777-84. 2003
    ..Although similar, there appear to be important differences in the CD4+ epitope repertoires of congenital and acquired hemophilia patients...
  3. ncbi request reprint Epitope repertoire of human CD4(+) T cells on the A3 domain of coagulation factor VIII
    M T Reding
    Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, 420 Delaware Street SE, MMC 480, Minneapolis, MN 55455, USA
    J Thromb Haemost 2:1385-94. 2004
    ..In contrast, CD4(+) T cells sensitized to sequences 1691-1710 and 1941-60, which are recognized by healthy subjects and hemophilia A patients without inhibitors, might curb inhibitor synthesis...
  4. ncbi request reprint Immunological aspects of inhibitor development
    M T Reding
    Division of Hematology, Oncology and Transplantation, Hemophilia and Thrombosis Center, University of Minnesota, Minneapolis, MN, USA
    Haemophilia 12:30-5; discussion 35-6. 2006
    ....
  5. ncbi request reprint CD4+ T cells specific for factor VIII as a target for specific suppression of inhibitor production
    M T Reding
    Department of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota, Minneapolis-St. Paul, USA
    Adv Exp Med Biol 489:119-34. 2001
    ....
  6. ncbi request reprint Successful liver transplantation in a patient with severe haemophilia A and a high-titre factor VIII inhibitor
    A A Ashrani
    Department of Medicine, University of Minnesota Medical School, Minneapolis, MN, USA
    Haemophilia 10:735-7. 2004
    ..This case illustrates the technical feasibility of OLT in some patients with high-titre inhibitors to FVIII, and suggests that immune tolerance may be induced by endogenously produced FVIII from the transplanted organ...
  7. doi request reprint Randomized, controlled, parallel-group trial of routine prophylaxis vs. on-demand treatment with sucrose-formulated recombinant factor VIII in adults with severe hemophilia A (SPINART)
    M J Manco-Johnson
    Department of Pediatrics, Hemophilia and Thrombosis Center, University of Colorado, Aurora, CO 80045, USA
    J Thromb Haemost 11:1119-27. 2013
    ..The benefits of routine prophylaxis vs. on-demand treatment with factor VIII products have not been evaluated in controlled clinical trials in older patients with hemophilia A...
  8. ncbi request reprint Thrombotic stroke associated with the use of porcine factor VIII in a patient with acquired haemophilia
    A A Ashrani
    Division of Hematology, Oncology and Transplantation, Department of Medicine, University of Minnesota Medical School, Minneapolis 55455, USA
    Haemophilia 8:56-8. 2002
    ..We speculate that platelet activation induced by pFVIII may have contributed to thrombosis and suggest that pFVIII be used with caution in elderly patients with pre-existing cardiovascular risk factors...
  9. ncbi request reprint Inhibitor treatment in haemophilias A and B: summary statement for the 2006 international consensus conference
    E Berntorp
    Department of Coagulation Disorders, Malmo University Hospital, Malmo, Sweden
    Haemophilia 12:1-7. 2006
    ..Finally, conference participants urged their colleagues to participate in the currently ongoing international trials of ITI...