Srinevas K Reddy

Summary

Affiliation: University of Pittsburgh
Country: USA

Publications

  1. doi request reprint Underlying steatohepatitis, but not simple hepatic steatosis, increases morbidity after liver resection: a case-control study
    Srinevas K Reddy
    Departments of Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Hepatology 56:2221-30. 2012
  2. doi request reprint Outcomes of curative treatment for hepatocellular cancer in nonalcoholic steatohepatitis versus hepatitis C and alcoholic liver disease
    Srinevas K Reddy
    Departments of Surgery, Hepatology, and Nutrition, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Hepatology 55:1809-19. 2012
  3. doi request reprint Post-operative pharmacologic thromboprophylaxis after major hepatectomy: does peripheral venous thromboembolism prevention outweigh bleeding risks?
    Srinevas K Reddy
    University of Pittsburgh Medical Center, Liver Cancer Center, UPMC Montefiore 7 South, Pittsburgh, PA 15213, USA
    J Gastrointest Surg 15:1602-10. 2011
  4. doi request reprint Major liver resection in elderly patients: a multi-institutional analysis
    Srinevas K Reddy
    Department of Surgery, Duke University Medical Center, Durham, NC, USA
    J Am Coll Surg 212:787-95. 2011
  5. pmc A standard definition of major hepatectomy: resection of four or more liver segments
    Srinevas K Reddy
    University of Pittsburgh Medical Center, Liver Cancer Center, Pittsburgh, PA 15213 2582, USA
    HPB (Oxford) 13:494-502. 2011
  6. doi request reprint Does neoadjuvant chemotherapy reveal disease precluding surgical treatment of initially resectable colorectal cancer liver metastases?
    Srinevas K Reddy
    University of Pittsburgh Medical Center, Liver Cancer Center, UPMC Montefiore, Pittsburgh, Pennsylvania
    J Surg Oncol 105:55-9. 2012
  7. doi request reprint Multiagent chemotherapy for isolated colorectal liver metastases: a single-centered retrospective study
    Srinevas K Reddy
    Department of Surgery, Duke University Medical Center, Box 3247, Durham, NC 27710, USA
    J Gastrointest Surg 13:74-84. 2009
  8. doi request reprint Timing of multimodality therapy for resectable synchronous colorectal liver metastases: a retrospective multi-institutional analysis
    Srinevas K Reddy
    Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA
    Ann Surg Oncol 16:1809-19. 2009
  9. doi request reprint Examining reoperation and readmission after hepatic surgery
    Andrew S Barbas
    Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA
    J Am Coll Surg 216:915-23. 2013
  10. doi request reprint Comparison of outcomes and the use of multimodality therapy in young and elderly people undergoing surgical resection of pancreatic cancer
    Andrew S Barbas
    Department of Surgery, Duke University Medical Center, Durham, North Carolina 27710, USA
    J Am Geriatr Soc 60:344-50. 2012

Detail Information

Publications36

  1. doi request reprint Underlying steatohepatitis, but not simple hepatic steatosis, increases morbidity after liver resection: a case-control study
    Srinevas K Reddy
    Departments of Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Hepatology 56:2221-30. 2012
    ..316; 95% confidence interval [95% CI]: 1.267-4.241; P = 0.007) and any hepatic-related (OR, 2.722; 95% CI: 1.201-6.168; P = 0.016) morbidity...
  2. doi request reprint Outcomes of curative treatment for hepatocellular cancer in nonalcoholic steatohepatitis versus hepatitis C and alcoholic liver disease
    Srinevas K Reddy
    Departments of Surgery, Hepatology, and Nutrition, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Hepatology 55:1809-19. 2012
    ..303), NASH patients had longer overall survival (OS) (median not reached versus 52 months; P = 0.009) independent of other clinicopathologic factors and type of curative treatment...
  3. doi request reprint Post-operative pharmacologic thromboprophylaxis after major hepatectomy: does peripheral venous thromboembolism prevention outweigh bleeding risks?
    Srinevas K Reddy
    University of Pittsburgh Medical Center, Liver Cancer Center, UPMC Montefiore 7 South, Pittsburgh, PA 15213, USA
    J Gastrointest Surg 15:1602-10. 2011
    ..The objective of this retrospective study is to evaluate the benefits and risks of post-operative pharmacologic thromboprophylaxis after major hepatectomy at two high volume academic centers...
  4. doi request reprint Major liver resection in elderly patients: a multi-institutional analysis
    Srinevas K Reddy
    Department of Surgery, Duke University Medical Center, Durham, NC, USA
    J Am Coll Surg 212:787-95. 2011
    ..The objective of this study was to assess the influence of age on postoperative outcomes after major hepatectomy among a contemporary cohort from 2 high volume centers...
  5. pmc A standard definition of major hepatectomy: resection of four or more liver segments
    Srinevas K Reddy
    University of Pittsburgh Medical Center, Liver Cancer Center, Pittsburgh, PA 15213 2582, USA
    HPB (Oxford) 13:494-502. 2011
    ..The objective of the present retrospective study is to specify the extent of hepatic resection that should describe a major hepatectomy...
  6. doi request reprint Does neoadjuvant chemotherapy reveal disease precluding surgical treatment of initially resectable colorectal cancer liver metastases?
    Srinevas K Reddy
    University of Pittsburgh Medical Center, Liver Cancer Center, UPMC Montefiore, Pittsburgh, Pennsylvania
    J Surg Oncol 105:55-9. 2012
    ..The objective of this study is to determine whether neoadjuvant chemotherapy reveals occult disease precluding surgical extirpation of initially resectable colorectal cancer liver metastases (CRCLM)...
  7. doi request reprint Multiagent chemotherapy for isolated colorectal liver metastases: a single-centered retrospective study
    Srinevas K Reddy
    Department of Surgery, Duke University Medical Center, Box 3247, Durham, NC 27710, USA
    J Gastrointest Surg 13:74-84. 2009
    ..The objective of this retrospective study was to determine the effect of multiagent chemotherapy on long-term survival after resection of CLM...
  8. doi request reprint Timing of multimodality therapy for resectable synchronous colorectal liver metastases: a retrospective multi-institutional analysis
    Srinevas K Reddy
    Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA
    Ann Surg Oncol 16:1809-19. 2009
    ..However, prospective randomized trials are needed to determine the optimal timing of chemotherapy...
  9. doi request reprint Examining reoperation and readmission after hepatic surgery
    Andrew S Barbas
    Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA
    J Am Coll Surg 216:915-23. 2013
    ..The goal of this investigation was to characterize the incidence, patterns, and risk factors for early reoperation and readmission after hepatectomy...
  10. doi request reprint Comparison of outcomes and the use of multimodality therapy in young and elderly people undergoing surgical resection of pancreatic cancer
    Andrew S Barbas
    Department of Surgery, Duke University Medical Center, Durham, North Carolina 27710, USA
    J Am Geriatr Soc 60:344-50. 2012
    ..To compare outcomes and the use of multimodality therapy in young and elderly people with pancreatic cancer undergoing surgical resection...
  11. doi request reprint Surgery versus intra-arterial therapy for neuroendocrine liver metastasis: a multicenter international analysis
    Skye C Mayo
    Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Ann Surg Oncol 18:3657-65. 2011
    ..We sought to examine the relative efficacy of surgical management versus intra-arterial therapy (IAT) for NELM and determine factors predictive of survival...
  12. pmc Hepatic resection for metastatic gastrointestinal stromal tumors in the tyrosine kinase inhibitor era
    Ryan S Turley
    Department of Surgery, Duke University Medical Center, Durham, NC 27110, USA
    Cancer 118:3571-8. 2012
    ..The objective of this study was to determine whether combination therapy for hepatic GIST metastases is associated with improved overall survival compared with reported outcomes from surgery or TKI therapy alone...
  13. ncbi request reprint Simultaneous diaphragm and liver resection: a propensity-matched analysis of postoperative morbidity
    George Z Li
    School of Medicine, Duke University Medical Center, Durham, NC 27710, USA
    J Am Coll Surg 216:402-11. 2013
    ....
  14. ncbi request reprint Incidence of benign disease in patients that underwent resection for presumed pancreatic cancer diagnosed by endoscopic ultrasonography (EUS) and fine-needle aspiration (FNA)
    Sebastian G de la Fuente
    Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA
    J Gastrointest Surg 14:1139-42. 2010
    ..In this study, we investigated the incidence of benign disease in patients that underwent resection for presumed pancreatic cancer diagnosed by EUS and EUS-guided FNA...
  15. doi request reprint Impact of simultaneous diaphragm resection during hepatectomy for treatment of metastatic colorectal cancer
    George Z Li
    School of Medicine, Duke University Medical Center, Durham, NC 27710, USA
    J Gastrointest Surg 16:1508-15. 2012
    ..The purpose of this study is to determine whether diaphragm resection during partial hepatectomy for metastatic colorectal cancer influences short-term perioperative outcomes and overall survival...
  16. doi request reprint Liver transplantation for glycogen storage disease type Ia
    Srinevas K Reddy
    Department of Surgery, Duke University Medical Center, Durham, NC, USA
    J Hepatol 51:483-90. 2009
    ..The objective of this retrospective study is to assess outcomes after liver transplantation (LT) for GSD Ia where the principal indication for transplantation was prevention of HCC...
  17. doi request reprint Robotic versus laparoscopic hepatectomy: a matched comparison
    Allan Tsung
    Division of Hepatobiliary and Pancreatic Surgery and Division of Surgical Oncology, Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh Division of General and Oncologic Surgery, Department of Surgery, University of Maryland Medical Center, Baltimore, MD
    Ann Surg 259:549-55. 2014
    ..To perform a matched comparison of surgical and postsurgical outcomes between our robotic and laparoscopic hepatic resection experience...
  18. ncbi request reprint Simultaneous resections of colorectal cancer and synchronous liver metastases: a multi-institutional analysis
    Srinevas K Reddy
    Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA
    Ann Surg Oncol 14:3481-91. 2007
    ..This multi-institutional retrospective study compared postoperative outcomes after simultaneous and staged colorectal and hepatic resections...
  19. ncbi request reprint Extended hepatic resection for gallbladder cancer
    Srinevas K Reddy
    Division of General Surgery, Department of Surgery, Duke University Medical Center, Box 3247, Durham, NC 27710, USA
    Am J Surg 194:355-61. 2007
    ....
  20. ncbi request reprint RNA aptamer-targeted inhibition of NF-kappa B suppresses non-small cell lung cancer resistance to doxorubicin
    Jing Mi
    Department of Surgery, Duke University Medical Center, Durham, North Carolina, USA
    Mol Ther 16:66-73. 2008
    ..These studies provide important insights into the mechanisms of Dox-induced chemoresistance, and they demonstrate a novel, effective, and clinically practical strategy for interfering with these processes...
  21. doi request reprint Hepatic parenchymal transection with vascular staplers: a comparative analysis with the crush-clamp technique
    Srinevas K Reddy
    Department of Surgery, Duke University Medical Center, Durham, NC, USA
    Am J Surg 196:760-7. 2008
    ..This retrospective study compares the safety and efficacy of hepatic parenchymal transection using vascular staplers (VS) and the crush-clamp (CC) technique...
  22. doi request reprint Indeterminate pulmonary nodules represent lung metastases in a significant portion of patients undergoing liver resection for malignancy
    Stephanie Downs-Canner
    Division of Hepatobiliary and Pancreatic Surgery, UPMC Liver Cancer Center, Montefiore Hospital, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    J Gastrointest Surg 16:2256-9. 2012
    ..The objective of this study is to determine how often IPN detected on imaging before surgery for hepatic malignancies represent lung metastases...
  23. ncbi request reprint Neuroendocrine liver metastases
    Srinevas K Reddy
    Department of Surgery, Duke University Medical Center, Box 3247, Durham, NC 27710, USA
    Surg Clin North Am 90:853-61. 2010
    ....
  24. ncbi request reprint Addition of bevacizumab to irinotecan- and oxaliplatin-based preoperative chemotherapy regimens does not increase morbidity after resection of colorectal liver metastases
    Srinevas K Reddy
    Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA
    J Am Coll Surg 206:96-106. 2008
    ..The objective of this retrospective study was to determine if addition of bevacizumab to iri/oxal preoperative chemotherapy increases morbidity after hepatic resection...
  25. ncbi request reprint Liver-directed surgery for metastatic squamous cell carcinoma to the liver: results of a multi-center analysis
    Timothy M Pawlik
    Department of Surgery, Johns Hopkins School of Medicine, Baltimore, MD, USA
    Ann Surg Oncol 14:2807-16. 2007
    ..The role of hepatic resection for metastatic squamous cell carcinoma (SCC) remains unknown. The current study evaluates the role of hepatic resection in patients with metastatic SCC to the liver...
  26. ncbi request reprint Resection of hepatocellular adenoma in patients with glycogen storage disease type Ia
    Srinevas K Reddy
    Department of Surgery, Duke University Medical Center, Box 3247, Durham, NC 27710, USA
    J Hepatol 47:658-63. 2007
    ..The objective of this retrospective study is to assess the safety and effectiveness of HCA resection in GSD Ia patients...
  27. doi request reprint Laparoscopic liver resection
    Srinevas K Reddy
    Department of Surgery, UPMC Liver Cancer Center, Starzl Transplant Institute, University of Pittsburgh, 3459 Fifth Avenue, UPMC Montefiore 7 South, Pittsburgh, PA 15213, USA
    World J Surg 35:1478-86. 2011
    ....
  28. doi request reprint Surgical management of hepatic neuroendocrine tumor metastasis: results from an international multi-institutional analysis
    Skye C Mayo
    Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Ann Surg Oncol 17:3129-36. 2010
    ..We sought to define the efficacy of the surgical management of NELM in a large multicenter international cohort of patients...
  29. pmc Prevalence of nonalcoholic steatohepatitis among patients with resectable intrahepatic cholangiocarcinoma
    Srinevas K Reddy
    Department of Surgery, University of Maryland School of Medicine, Baltimore, MD, USA
    J Gastrointest Surg 17:748-55. 2013
    ..The objective of this report was to determine the prevalence of underlying nonalcoholic steatohepatitis in resectable intrahepatic cholangiocarcinoma...
  30. doi request reprint Venous thromboembolism after hepatic resection: analysis of 5,706 patients
    Ryan S Turley
    Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA
    J Gastrointest Surg 16:1705-14. 2012
    ..The objective of our analysis was to identify perioperative predictors of postoperative VTE in patients undergoing resection...
  31. ncbi request reprint Resection of noncolorectal nonneuroendocrine liver metastases: a comparative analysis
    Srinevas K Reddy
    Department of Surgery, Duke University Medical Center, Durham, NC 27713, USA
    J Am Coll Surg 204:372-82. 2007
    ..Although established for metastatic colorectal (CR) and neuroendocrine (NE) malignancies, the role of partial hepatectomy in management of metastases from other primaries (NCRNE) is not well-defined...
  32. doi request reprint Synchronous colorectal liver metastases: is it time to reconsider traditional paradigms of management?
    Srinevas K Reddy
    Department of Surgery, Duke University Medical Center, Durham, NC, USA
    Ann Surg Oncol 16:2395-410. 2009
    ..This review describes the rationale for this treatment approach and the recent developments suggesting that this management paradigm should be reconsidered...
  33. doi request reprint Defining criteria for selective operative management of pancreatic cystic lesions: does size really matter?
    Eugene P Ceppa
    Department of Surgery, Duke University Medical Center, P O Box 3247, Durham, NC 27710, USA
    J Gastrointest Surg 14:236-44. 2010
    ..The objective of this study was to evaluate risk factors for malignancy in a large series of patients undergoing resection of suspected pancreatic cystic neoplasms...
  34. doi request reprint Surgical management of gallbladder cancer
    Srinevas K Reddy
    Department of Surgery, Duke University Medical Center, Box 3247, Durham, NC 27710, USA
    Surg Oncol Clin N Am 18:307-24, ix. 2009
    ..Large retrospective and underpowered prospective studies have suggested benefit to adjuvant chemotherapy or radiotherapy; however, these results need to be confirmed with large prospective randomized trials...
  35. ncbi request reprint Extended resection for pancreatic adenocarcinoma
    Srinevas K Reddy
    Duke University Medical Center, Box 3247, Durham, North Carolina 27710, USA
    Oncologist 12:654-63. 2007
    ..The disappointing experience with extended resections underscores the need for better adjuvant systemic strategies and the interdisciplinary care of patients with pancreatic adenocarcinoma...
  36. ncbi request reprint NF-kappaB inhibition by an adenovirus expressed aptamer sensitizes TNFalpha-induced apoptosis
    Jing Mi
    Department of Surgery, Duke University Medical Center, Box 2633, MSRB Building, Durham, NC 27710, USA
    Biochem Biophys Res Commun 359:475-80. 2007
    ..RNA aptamer inhibition of NF-kappaB offers exciting opportunities for sensitizing inflammatory and tumor cells to TNFalpha-induced apoptosis...