Peter W Reddien

Summary

Affiliation: University of Utah
Country: USA

Publications

  1. ncbi The engulfment process of programmed cell death in caenorhabditis elegans
    Peter W Reddien
    Dept of Neurobiology and Anatomy, University of Utah School of Medicine, Salt Lake City, Utah 84132, USA
    Annu Rev Cell Dev Biol 20:193-221. 2004
  2. ncbi Fundamentals of planarian regeneration
    Peter W Reddien
    University of Utah School of Medicine, Department of Neurobiology and Anatomy, Salt Lake City, UT 84132 3401, USA
    Annu Rev Cell Dev Biol 20:725-57. 2004
  3. ncbi SMEDWI-2 is a PIWI-like protein that regulates planarian stem cells
    Peter W Reddien
    Howard Hughes Medical Institute, Department of Neurobiology and Anatomy, University of Utah School of Medicine, Salt Lake City, UT 84132, USA
    Science 310:1327-30. 2005
  4. ncbi Identification of genes needed for regeneration, stem cell function, and tissue homeostasis by systematic gene perturbation in planaria
    Peter W Reddien
    Department of Neurobiology and Anatomy, University of Utah School of Medicine, Salt Lake City, 84132, USA
    Dev Cell 8:635-49. 2005
  5. ncbi Ingestion of bacterially expressed double-stranded RNA inhibits gene expression in planarians
    Phillip A Newmark
    Department of Cell and Structural Biology, University of Illinois at Urbana Champaign, B107 Chemical Life Sciences Laboratory, 601 South Goodwin Avenue, Urbana, IL 61801, USA
    Proc Natl Acad Sci U S A 100:11861-5. 2003
  6. ncbi DPL-1 DP, LIN-35 Rb and EFL-1 E2F act with the MCD-1 zinc-finger protein to promote programmed cell death in Caenorhabditis elegans
    Peter W Reddien
    Department of Biology, Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA
    Genetics 175:1719-33. 2007
  7. ncbi BMP signaling regulates the dorsal planarian midline and is needed for asymmetric regeneration
    Peter W Reddien
    MIT Biology, Whitehead Institute, 9 Cambridge Center, Cambridge, MA 02138, USA
    Development 134:4043-51. 2007
  8. ncbi Smed-betacatenin-1 is required for anteroposterior blastema polarity in planarian regeneration
    Christian P Petersen
    Whitehead Institute for Biomedical Research, 9 Cambridge Center, Cambridge, MA 02142, USA
    Science 319:327-30. 2008

Detail Information

Publications8

  1. ncbi The engulfment process of programmed cell death in caenorhabditis elegans
    Peter W Reddien
    Dept of Neurobiology and Anatomy, University of Utah School of Medicine, Salt Lake City, Utah 84132, USA
    Annu Rev Cell Dev Biol 20:193-221. 2004
    ..The known mechanisms for cell-corpse engulfment leave much to be discovered concerning this fundamental aspect of metazoan biology...
  2. ncbi Fundamentals of planarian regeneration
    Peter W Reddien
    University of Utah School of Medicine, Department of Neurobiology and Anatomy, Salt Lake City, UT 84132 3401, USA
    Annu Rev Cell Dev Biol 20:725-57. 2004
    ....
  3. ncbi SMEDWI-2 is a PIWI-like protein that regulates planarian stem cells
    Peter W Reddien
    Howard Hughes Medical Institute, Department of Neurobiology and Anatomy, University of Utah School of Medicine, Salt Lake City, UT 84132, USA
    Science 310:1327-30. 2005
    ..We suggest that SMEDWI-2 functions within dividing neoblasts to support the generation of cells that promote regeneration and homeostasis...
  4. ncbi Identification of genes needed for regeneration, stem cell function, and tissue homeostasis by systematic gene perturbation in planaria
    Peter W Reddien
    Department of Neurobiology and Anatomy, University of Utah School of Medicine, Salt Lake City, 84132, USA
    Dev Cell 8:635-49. 2005
    ....
  5. ncbi Ingestion of bacterially expressed double-stranded RNA inhibits gene expression in planarians
    Phillip A Newmark
    Department of Cell and Structural Biology, University of Illinois at Urbana Champaign, B107 Chemical Life Sciences Laboratory, 601 South Goodwin Avenue, Urbana, IL 61801, USA
    Proc Natl Acad Sci U S A 100:11861-5. 2003
    ..These results pave the way for large-scale screens for genes involved in regenerative processes...
  6. ncbi DPL-1 DP, LIN-35 Rb and EFL-1 E2F act with the MCD-1 zinc-finger protein to promote programmed cell death in Caenorhabditis elegans
    Peter W Reddien
    Department of Biology, Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA
    Genetics 175:1719-33. 2007
    ..We propose that the DPL-1 DP, MCD-1 zinc finger, EFL-1 E2F, LIN-35 Rb, LIN-37 Mip40, and LIN-52 dLin52 proteins act together in transcriptional regulation to promote programmed cell death...
  7. ncbi BMP signaling regulates the dorsal planarian midline and is needed for asymmetric regeneration
    Peter W Reddien
    MIT Biology, Whitehead Institute, 9 Cambridge Center, Cambridge, MA 02138, USA
    Development 134:4043-51. 2007
    ..We suggest injured animals that lack left-right symmetry reset their midline through modulation of BMP activity as an early and necessary event in regeneration...
  8. ncbi Smed-betacatenin-1 is required for anteroposterior blastema polarity in planarian regeneration
    Christian P Petersen
    Whitehead Institute for Biomedical Research, 9 Cambridge Center, Cambridge, MA 02142, USA
    Science 319:327-30. 2008
    ..Our data suggest that beta-catenin specifies the posterior character of the anteroposterior axis throughout the Bilateria and specifies regeneration polarity in planarians...