Ana Recober

Summary

Affiliation: University of Iowa
Country: USA

Publications

  1. ncbi request reprint Olcegepant, a non-peptide CGRP1 antagonist for migraine treatment
    Ana Recober
    Department of Neurology, 2RCP, University of Iowa, Iowa City, IA 52242, USA
    IDrugs 10:566-74. 2007
  2. pmc Calcitonin gene-related peptide: an update on the biology
    Ana Recober
    Departments of Neurology, University of Iowa, Iowa City, Iowa 52242, USA
    Curr Opin Neurol 22:241-6. 2009
  3. pmc Induction of multiple photophobic behaviors in a transgenic mouse sensitized to CGRP
    Ana Recober
    Department of Neurology, University of Iowa, Iowa City, IA 52242, USA
    Neuropharmacology 58:156-65. 2010
  4. pmc Modulation of CGRP-induced light aversion in wild-type mice by a 5-HT(1B/D) agonist
    Eric A Kaiser
    Department of Molecular Physiology and Biophysics, University of Iowa, Iowa City, Iowa 52242, USA
    J Neurosci 32:15439-49. 2012
  5. pmc Light aversion in mice depends on nonimage-forming irradiance detection
    Stewart Thompson
    Department of Ophthalmology and Visual Sciences and The Howard Hughes Medical Institute, University of Iowa, Iowa City, IA 52242, USA
    Behav Neurosci 124:821-7. 2010
  6. pmc Role of calcitonin gene-related peptide in light-aversive behavior: implications for migraine
    Ana Recober
    Department of Neurology, University of Iowa, Iowa City, Iowa 52242, USA
    J Neurosci 29:8798-804. 2009
  7. pmc Calcitonin gene-related peptide: A molecular link between obesity and migraine?
    Ana Recober
    Headache Division Department of Neurology, University of Iowa, IA, USA
    Drug News Perspect 23:112-7. 2010
  8. ncbi request reprint Menstrual migraine
    Ana Recober
    Department of Neurology, Division of Head and Facial Pain, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, 2 RCP, Iowa City, IA 52242, USA
    Curr Neurol Neurosci Rep 5:93-8. 2005

Collaborators

Detail Information

Publications8

  1. ncbi request reprint Olcegepant, a non-peptide CGRP1 antagonist for migraine treatment
    Ana Recober
    Department of Neurology, 2RCP, University of Iowa, Iowa City, IA 52242, USA
    IDrugs 10:566-74. 2007
    ..For a successful marketing of olcegepant, larger clinical trials and the development of an effective oral formulation will be necessary...
  2. pmc Calcitonin gene-related peptide: an update on the biology
    Ana Recober
    Departments of Neurology, University of Iowa, Iowa City, Iowa 52242, USA
    Curr Opin Neurol 22:241-6. 2009
    ..Especial attention was given to those published within the last year...
  3. pmc Induction of multiple photophobic behaviors in a transgenic mouse sensitized to CGRP
    Ana Recober
    Department of Neurology, University of Iowa, Iowa City, IA 52242, USA
    Neuropharmacology 58:156-65. 2010
    ..Our findings confirm the robust CGRP-induced light-aversive phenotype of nestin/hRAMP1 mice, which can be a surrogate of photophobia, and validates its usefulness as a model of migraine and other disorders associated with photophobia...
  4. pmc Modulation of CGRP-induced light aversion in wild-type mice by a 5-HT(1B/D) agonist
    Eric A Kaiser
    Department of Molecular Physiology and Biophysics, University of Iowa, Iowa City, Iowa 52242, USA
    J Neurosci 32:15439-49. 2012
    ..Thus, we demonstrate that activation of endogenous CGRP receptors is sufficient to elicit light aversion in mice, which can be modulated by a drug commonly used to treat migraine...
  5. pmc Light aversion in mice depends on nonimage-forming irradiance detection
    Stewart Thompson
    Department of Ophthalmology and Visual Sciences and The Howard Hughes Medical Institute, University of Iowa, Iowa City, IA 52242, USA
    Behav Neurosci 124:821-7. 2010
    ..Further, the differing effects of disease suggest that negative masking and light aversion are distinct responses with specialized nonimage-forming irradiance detection pathways...
  6. pmc Role of calcitonin gene-related peptide in light-aversive behavior: implications for migraine
    Ana Recober
    Department of Neurology, University of Iowa, Iowa City, Iowa 52242, USA
    J Neurosci 29:8798-804. 2009
    ..Moreover, they validate CGRP hypersensitive mice as a tool for exploring the neurobiology and novel therapies for migraine and other disorders involving photophobia...
  7. pmc Calcitonin gene-related peptide: A molecular link between obesity and migraine?
    Ana Recober
    Headache Division Department of Neurology, University of Iowa, IA, USA
    Drug News Perspect 23:112-7. 2010
    ..Enhanced trigeminal CGRP production in obese susceptible individuals may lower the threshold necessary to trigger migraine attacks, leading to more frequent episodes and eventually to chronic migraine...
  8. ncbi request reprint Menstrual migraine
    Ana Recober
    Department of Neurology, Division of Head and Facial Pain, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, 2 RCP, Iowa City, IA 52242, USA
    Curr Neurol Neurosci Rep 5:93-8. 2005
    ..Some patients do not require prophylaxis when they can abort their attacks effectively, whereas others may benefit from perimenstrual prophylaxis or standard migraine prophylaxis...