Research Topics
Species | Adrian RecinosSummaryAffiliation: University of Texas Medical Branch Country: USA Publications
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Detail Information
Publications
Liver gene expression associated with diet and lesion development in atherosclerosis-prone mice: induction of components of alternative complement pathwayAdrian Recinos
Department of Internal Medicine, University of Texas Medical Branch, Galveston, Texas 77555 1060, USA
Physiol Genomics 19:131-42. 2004..These findings suggest that induction of the alternative complement pathway may be an additional mechanism by which a high-fat/Western diet accelerates atherosclerosis...
Angiotensin II induces IL-6 expression and the Jak-STAT3 pathway in aortic adventitia of LDL receptor-deficient miceAdrian Recinos
Department of Medicine, University of Texas Medical Branch, Galveston, TX 77555, USA
Atherosclerosis 194:125-33. 2007..These findings define cytokine profiles in the A-II infusion model and demonstrate that IL-6, produced by activated macrophages and fibroblasts in the adventitia, induces the Jak-STAT3 pathway during early A-II-induced atherosclerosis...
Aortic adventitial fibroblasts participate in angiotensin-induced vascular wall inflammation and remodelingBrian C Tieu
Department of Biochemistry, University of Texas Medical Branch, Galveston, TX 77555 1060, USA
J Vasc Res 48:261-72. 2011..Our objective was to explore the contribution of these cells to angiotensin II (Ang II)-induced aortic inflammation and adventitial expansion...
An adventitial IL-6/MCP1 amplification loop accelerates macrophage-mediated vascular inflammation leading to aortic dissection in miceBrian C Tieu
Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, Texas, USA
J Clin Invest 119:3637-51. 2009....
RhoA mediates angiotensin II-induced phospho-Ser536 nuclear factor kappaB/RelA subunit exchange on the interleukin-6 promoter in VSMCsRuwen Cui
Department of Medicine, University of Texas Medical Branch, Galveston, TX 77555, USA
Circ Res 99:723-30. 2006..Together, these data indicate a novel mechanism for Ang II-induced NF-kappaB activation in VSMCs, mediated by RhoA-induced phospho-Ser536 RelA formation, IL-6 expression, and vascular inflammation...
Vascular inflammation and the renin-angiotensin systemAllan R Brasier
Department of Medicine, The University of Texas Medical Branch, Galveston, 77555 1060, USA
Arterioscler Thromb Vasc Biol 22:1257-66. 2002..Moreover, antagonizing the vascular nuclear factor-kappaB and/or hepatic JAK/STAT pathways may modulate the atherosclerotic process...
Discovery proteomics and nonparametric modeling pipeline in the development of a candidate biomarker panel for dengue hemorrhagic feverAllan R Brasier
Department of Internal Medicine, University of Texas Medical Branch UTMB, Galveston, Texas, USA
Clin Transl Sci 5:8-20. 2012..Although this DHF risk model will need validation in a larger cohort, we conclude that approaches to develop predictive biomarker models for disease outcome will need to incorporate nonparametric modeling approaches...
